Clinical trials · Michigan
Parkinson’s disease clinical trials in Michigan
We’re tracking 21 recruiting parkinson’s disease studies with a site in Michigan — including Phase 1, Phase 1/Phase 2, Phase 2, Phase 2/Phase 3, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in Michigan
- NCT06679374RecruitingPhase 2
Can varenicline help reduce falls in Parkinson disease?
This phase 2 trial tests a medicine called varenicline (brand name Chantix) to see if it can reduce falls in people with Parkinson disease who also have a specific brain change (loss of a chemical called acetylcholine in the back of the brain) and mild cognitive problems. The study will help determine if this medicine is safe and effective for this group.
Ann Arbor, MichiganAges 45 years+ - NCT06680830RecruitingPhase 2
Testing NEU-411 for early Parkinson's with LRRK2 gene change
This trial tests an experimental drug called NEU-411 for people with early Parkinson's disease who have a specific genetic change (LRRK2). It aims to see if the drug can slow the disease progression.
Farmington Hills, MichiganAges 40–80 - NCT07154511RecruitingPhase 1/Phase 2
Tributyrin for Parkinson's with memory problems
This trial tests a supplement called tributyrin to see if it can help with thinking and memory problems in people with Parkinson's disease. You may be able to join if you have both Parkinson's and mild cognitive impairment or dementia.
Ann Arbor, MichiganAges 45 years+ - NCT07422675RecruitingPhase 1
Study of a new treatment for Parkinson's with motor fluctuations
This study tests a new single-dose treatment for Parkinson's disease to see if it can help reduce 'off' time—when medication wears off and symptoms return. It is for people who experience motor fluctuations and are already on a stable medication routine.
Farmington Hills, MichiganAges 40–80 - NCT06976268RecruitingPhase 2/Phase 3
Testing BHV-8000 for early Parkinson's disease
This study tests a new once-daily pill called BHV-8000 in people who were recently diagnosed with early Parkinson's disease and are not yet on medication. The goal is to see if it can slow the progression of symptoms and improve quality of life.
Farmington Hills, MichiganAges 40–80 - NCT07543861RecruitingPhase 1
Standing Balance Training Study for Parkinson's Disease
This study tests a new way to help people with Parkinson's disease improve their balance and standing ability through guided exercises in a lab setting. Researchers want to see if this approach can safely help reduce balance problems and fall risk.
Ann Arbor, MichiganAges 50 years+ - NCT07005180RecruitingPhase 2
Carbon monoxide gas for Parkinson's disease
This trial tests if a low dose of carbon monoxide (HBI-002) is safe and helpful for people with Parkinson's disease. It requires specific health criteria and stable Parkinson's medication.
Farmington Hills, MichiganAges 40–80 - NCT06944522RecruitingPhase 3
Cell therapy for Parkinson's symptoms
This study tests a new cell therapy called bemdaneprocel to see if it can reduce Parkinson's symptoms and “off” time. The treatment involves transplanting special cells into the brain to help replace lost dopamine-producing cells.
Ann Arbor, MichiganAges 45–75 - NCT06765668RecruitingPhase 4
Study of CREXONT for Parkinson's with wearing-off episodes
This study tests how well CREXONT, an extended-release form of carbidopa-levodopa, controls symptoms in people with Parkinson's who experience predictable 'off' periods when their regular medication wears off. The goal is to see if it can reduce the daily hours of poor mobility.
Farmington Hills, MichiganAges 18 years+ - NCT06809400RecruitingPhase 1
Study of LY4006896 in healthy people and those with Parkinson's
This study tests an injectable antibody called LY4006896, first in healthy volunteers and then in people with Parkinson's disease. It aims to see if the drug is safe and how it works in the body.
Farmington Hills, MichiganAges 30–85 - NCT07599696Recruiting
Speech Amplification Devices for Parkinson Disease
This research study tests special amplification devices designed to help people with Parkinson disease or related conditions speak more clearly. The goal is to improve how well others can understand your speech.
East Lansing, MichiganAges 50 years+ - NCT07174310RecruitingPhase 3
Prasinezumab for early Parkinson's disease
This study tests a new medication called prasinezumab, given through a vein (IV), to see if it can slow the progression of early-stage Parkinson's disease. It is for people who are on only one Parkinson's medication and have not yet developed motor complications.
Farmington Hills, MichiganAges 50–85 - NCT06285643RecruitingPhase 2
Gene therapy for moderate Parkinson's disease
This trial tests a gene therapy (AAV2-GDNF) to see if it can slow or improve symptoms of Parkinson's disease. It is for people who have had moderate Parkinson's for 4 to 10 years and still respond to levodopa therapy.
East Lansing, MichiganAges 45–75 - NCT07432958RecruitingPhase 2
Study of AP-472 with levodopa for Parkinson's motor fluctuations
This trial tests an experimental drug called AP-472, taken alongside your regular Parkinson's medications, to see if it can reduce the amount of "OFF" time you experience each day when symptoms return between doses of levodopa.
Ann Arbor, MichiganAges 30–80 - NCT07330258Recruiting
Observing Parkinson's over time in people still having movement symptoms
This study follows people with Parkinson's disease who still have movement symptoms despite taking medication. It aims to understand how the disease changes over time, which could help improve future treatments.
Ann Arbor, MichiganAges 45–75 - NCT01989013Enrolling by invitation
CranioSacral therapy for people with Parkinson’s disease
This study looks at whether a hands-on therapy called CranioSacral Integrated Therapy can improve symptoms in people with Parkinson’s disease. If you have Parkinson’s, the goal is to see whether this treatment changes how you feel or function.
Ann Arbor, MichiganAges 18 years+ - NCT04373317RecruitingPhase 4
Comparing two medicines for hallucinations in Parkinson's disease
This study compares two drugs, pimavanserin and quetiapine, to see which works better for hallucinations or delusions caused by Parkinson's disease. The goal is to help patients manage these symptoms more effectively.
Ann Arbor, MichiganAges 40 years+ - NCT04477785Recruiting
Study to track Parkinson’s signs using imaging, spinal fluid, and genes
This study is building a large, detailed group of people—some with Parkinson’s and some at higher risk—to understand early changes over time. It uses brain imaging (DaTscan SPECT), sometimes spinal fluid tests (lumbar puncture), and genetic information to help researchers better measure disease and develop future treatments.
Ann Arbor, MichiganAges 30 years+ - NCT01799915Recruiting
Study of causes and progression of synuclein-related nerve conditions
This study follows people over time to better understand “synucleinopathies,” which are conditions that affect the nervous system as it develops and progresses. You may be asked to return for visits and report symptoms, especially those that happen when you stand up.
Ann Arbor, MichiganAges 18 years+ - NCT07642908Recruiting
Brain imaging study of Parkinson's disease with LRRK2 gene mutations
This research study uses advanced MRI brain imaging to understand how a specific gene mutation (LRRK2) affects certain brain chemicals in people with Parkinson's disease. The goal is to learn more about how this genetic form of Parkinson's works, which could help develop better treatments.
Ann Arbor, MichiganAges 45 years+ - NCT07284784RecruitingPhase 2/Phase 3
Buntanetap for Parkinson's disease study
This trial tests an investigational drug called buntanetap in people with Parkinson's disease. It aims to see if the drug can improve symptoms. There are two groups: those who've taken buntanetap before (Cohort 1) and those with a deep brain stimulator (DBS) implant for at least a year (Cohort 2).
Farmington Hills, MichiganAges 40–85
Parkinson’s disease trials by city in Michigan
Where these studies are running in Michigan
Institutions with a site for the recruiting parkinson’s disease studies listed above.
- Quest Research Institute · 10 studies
- University of Michigan · 8 studies
- Michigan State University · 2 studies
- Naturalmed therapy
- Site-015
- University of Michigan Health System (UMHS) - C.S. Mott Children's Hospital - Hematology Oncology Clinic
- VA Ann Arbor Healthcare System
What taking part in a parkinson’s disease study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Parkinson’s disease trials in other states
Common questions
- Are there parkinson’s disease clinical trials in Michigan?
- Yes. We're currently tracking 21 recruiting parkinson’s disease studies with a site in Michigan, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a parkinson’s disease study in Michigan?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Michigan to take part?
- Not necessarily. These studies have a site in Michigan, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a parkinson’s disease trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New parkinson’s disease studies open in Michigan regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.