Clinical trials
Paroxysmal AF clinical trials
Below are recruiting paroxysmal af clinical trials, each written for real people, not researchers. We’re tracking 22 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06647485Recruiting
Pulsed Field Ablation for Paroxysmal Atrial Fibrillation
This trial studies a new procedure called pulsed field ablation to treat brief episodes of atrial fibrillation (AFib). The goal is to see if it can help reset the heart's natural electrical system and reduce symptoms.
Aalst, BelgiumAges 18–70 - NCT07487714Enrolling by invitationPhase 4
Comparing amiodarone doses for paroxysmal AF
This study compares three different daily doses of the heart rhythm medication amiodarone to find the most effective one for preventing episodes of paroxysmal atrial fibrillation. Participants will take one of three doses (100, 200, or 400 mg) for up to 12 months, and the study will monitor how well each dose controls the irregular heartbeat.
TomskAges 18–80 - NCT07523620Recruiting
Heart rhythm procedure with left atrial appendage closure
This trial tests a procedure that closes off a small pouch in the heart (left atrial appendage) while also treating irregular heartbeat (atrial fibrillation) with a catheter ablation procedure. The goal is to reduce your stroke risk and treat your symptoms without needing blood thinners long-term.
Brussels, B CAP RAges 18 years+ - NCT07792239RecruitingPhase 2
Study of budiodarone for atrial fibrillation
This study tests a new medicine, budiodarone, to help control atrial fibrillation (an irregular heartbeat) in people who haven't been helped by other treatments. It may reduce the time spent in AF and improve symptoms.
GdyniaAges 18–80 - NCT06784466Recruiting
New ablation procedure for atrial fibrillation
This study is testing a new type of ablation procedure for atrial fibrillation (an irregular heart rhythm). It uses special energy to create scar tissue in the heart to block faulty electrical signals. If you have AF that isn’t controlled by medication, you may qualify.
Birmingham, AlabamaAges 18–80 - NCT07439016Recruiting
LA function after pulse field ablation for paroxysmal AF
This trial tests how pulse field ablation (a treatment that uses short electrical pulses to correct irregular heartbeats) affects the left atrium's function in people with paroxysmal atrial fibrillation (AFib that comes and goes). It may help if you have paroxysmal AFib and are in normal rhythm at the start of the procedure.
PragueAges 18 years+ - NCT06801392Recruiting
Pulsed-field ablation for non-paroxysmal atrial fibrillation
This trial tests a new way to treat non-paroxysmal atrial fibrillation (AF) using a focused type of ablation (pulsed-field energy) on specific areas of the heart. It aims to see if targeting the left atrial wall and mitral isthmus can improve outcomes for people who have not had this procedure before.
PragueAges 18 years+ - NCT07298473Recruiting
Redo ablation for recurrent atrial fibrillation with Sphere-9 catheter
This trial tests a new catheter and system for people who have had one previous ablation for atrial fibrillation but still have symptoms. It aims to see if a repeat procedure can safely and effectively treat recurrent episodes.
Birmingham, AlabamaAges 18 years+ - NCT07181590Recruiting
Balloon-based ablation for atrial fibrillation: post-approval study
This trial tests a balloon catheter that uses pulsed field energy to treat atrial fibrillation (AF) in people who have tried medication without success. It aims to see how well it works in real-world use.
LinzAges 18 years+ - NCT06510556Recruiting
Testing a new mapping and ablation system for AFib
This study tests a new device (FARAFLEX) that uses pulsed field energy to treat atrial fibrillation (AFib). You may qualify if you have persistent or paroxysmal AFib symptoms and have not had a prior ablation.
BrusselsAges 18 years+ - NCT06249347Recruiting
New ablation approach for persistent atrial fibrillation with stroke risk
This trial tests a new type of catheter ablation (using heat to create scar lines in the heart) for people with persistent atrial fibrillation who have a higher risk of stroke or bleeding. It aims to see if this approach can help prevent strokes and reduce the need for long-term blood thinners.
Wenzhou, ZhejiangAges 18 years+ - NCT06199180Recruiting
Comparing two ablation methods for repeat atrial fibrillation treatment
This trial tests a newer type of energy (pulsed field ablation) against the standard heat-based method (radiofrequency) for people who have already had one ablation and now have atrial fibrillation again. The goal is to see which works better for keeping your heart in a normal rhythm.
GroningenAges 18–80 - NCT06828939Recruiting
Balloon treatment for atrial fibrillation
This trial tests a new balloon device that uses gentle energy pulses to treat atrial fibrillation (AF), a type of irregular heartbeat. It may help people whose AF has not improved with medication.
Prague, Czech RepublicAges 18–75 - NCT06754176Recruiting
Alcohol and AFib: Avoiding vs. Allowing Drinking
This study tests whether avoiding alcohol completely for two weeks helps people with AFib have fewer episodes, compared to allowing regulated drinking. You will be randomly assigned to one of the two groups.
San Francisco, CaliforniaAges 21 years+ - NCT06099730Recruiting
Pulsed field ablation for atrial fibrillation
This trial tests a new method called pulsed field ablation to treat atrial fibrillation (AF), a type of irregular heartbeat. It aims to safely stop AF episodes by targeting specific areas in the heart, and may help people with paroxysmal (coming and going) or persistent AF who haven't had this procedure before.
Jonesboro, ArkansasAges 18–80 - NCT07324772Recruiting
Exercise program to improve symptoms in atrial fibrillation and heart failure
This study tests if starting a supervised exercise program can help older adults with both atrial fibrillation and a type of heart failure called HFpEF feel better and have a better quality of life. You'll be asked to join exercise sessions and have regular check-ins to see how you're doing.
Chicago, IllinoisAges 60–99 - NCT07321964Recruiting
Digital yoga for quality of life with atrial fibrillation
This trial tests if a digital yoga program can improve quality of life, blood pressure, and heart rate in people with atrial fibrillation. It offers a convenient way to practice yoga from home using a smartphone or tablet.
HerlevAges Any age - NCT07095959Recruiting
Ethanol vein infusion plus pulsed field ablation for paroxysmal AF
This study compares two treatments for paroxysmal atrial fibrillation (AF that comes and goes): using pulsed electric field ablation alone versus combining it with ethanol infusion into a specific vein. The goal is to see which approach works better for first-time ablation patients.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06960252Recruiting
Cycle length mapping for long-term atrial fibrillation
This study tests a new mapping technique to find chaotic electrical signals in the heart during persistent atrial fibrillation. It may help doctors better target treatment for people whose atrial fibrillation does not stop with medication.
Taipei, Outside USAges 20 years+ - NCT04606693Recruiting
Screening for sleep apnea before heart rhythm ablation
This study looks at whether checking for sleep apnea (breathing pauses during sleep) and treating it helps people prepare for atrial fibrillation ablation. It may help by improving outcomes for patients with atrial fibrillation who keep having episodes despite medication.
Madrid, MadridAges 18 years+ - NCT07734194Recruiting
Studying a new sedation combo for afib treatment
This trial tests a mild sedation method using remimazolam and fentanyl during a procedure called pulsed-field ablation for atrial fibrillation (afib). It aims to find a safe and effective way to keep you comfortable without deep sedation.
PragueAges 18 years+ - NCT07482020RecruitingPhase 2
SGLT2 inhibitor for atrial fibrillation, high blood pressure, and high blood sugar
This study tests whether a medication called an SGLT2 inhibitor (a type of diabetes drug) can improve the function of the upper left heart chamber in people who have paroxysmal atrial fibrillation, high blood pressure, and abnormal blood sugar levels. If you qualify, the trial may help your heart work better and reduce your risk of stroke.
Shanghai, Shanghai MunicipalityAges 18–80
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Common questions
- Are there clinical trials for paroxysmal af?
- Yes. Clin2 currently lists 22 recruiting paroxysmal af studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a paroxysmal af trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a paroxysmal af trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.