Clinical trials
Paroxysmal Atrial Fibrillation clinical trials
Below are recruiting paroxysmal atrial fibrillation clinical trials, each written for real people, not researchers. We’re tracking 183 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07626411RecruitingPhase 3
Blood Thinner Study for Irregular Heartbeat
This study tests a new blood thinner to prevent strokes and blood clots in people with atrial fibrillation (a common heart rhythm problem). You may qualify if you have atrial fibrillation and at least one risk factor for stroke, or if you've never taken a blood thinner before.
Dothan, AlabamaAges 18 years+ - NCT07324772Recruiting
Exercise program to improve symptoms in atrial fibrillation and heart failure
This study tests if starting a supervised exercise program can help older adults with both atrial fibrillation and a type of heart failure called HFpEF feel better and have a better quality of life. You'll be asked to join exercise sessions and have regular check-ins to see how you're doing.
Chicago, IllinoisAges 60–99 - NCT06938412Recruiting
Exercise and Fitbit for Afib patients
This study tests whether using a Fitbit activity tracker and a supportive exercise program helps people with AFib become more active. It may help you feel better and manage your heart rhythm.
New York, New YorkAges 18 years+ - NCT07621003Recruiting
PULSed Field Ablation for New-Onset Atrial Fibrillation
This study tests a newer ablation technique using pulsed electrical energy to treat atrial fibrillation (an irregular heartbeat). You may qualify if you were recently diagnosed with AF and haven't had ablation before.
Bad OeynhausenAges 18 years+ - NCT07772518Recruiting
Comparing two guidance methods for pulsed field ablation in atrial fibrillation
This trial compares two ways of guiding a procedure to treat atrial fibrillation (an irregular heartbeat). One uses special sound waves to see inside the heart, and the other uses electrical mapping. Both are used with the FARAPULSE system to deliver a type of energy called pulsed fields to fixed areas of the heart.
ZagrebAges 18 years+ - NCT07116525Recruiting
Study of heart mapping for abnormal rhythms
This trial tests a special catheter to map abnormal heart rhythms like ventricular tachycardia or atrial fibrillation. It may help patients who need a procedure to find and treat the source of these fast or irregular heartbeats.
BrugesAges 18 years+ - NCT07575269Recruiting
New ablation treatment for irregular heartbeat
This trial tests a new tool called FARAFLEX that uses pulsed electrical energy to treat atrial fibrillation (an irregular heart rhythm). The goal is to see if this method can safely stop AF symptoms in people whose medications haven't worked.
Jonesboro, ArkansasAges 18 years+ - NCT05204212Recruiting
Heart procedure to close an atrial clot risk pouch in kidney failure
This trial tests a heart procedure that closes a part of the heart called the left atrial appendage to help prevent stroke in people with an irregular heartbeat (atrial fibrillation) and very advanced kidney disease. It’s mainly for patients who can take the needed blood-thinner medicines and who do not already have a clot in that pouch.
Lübeck, Schleswig-HolsteinAges 18 years+ - NCT07734194Recruiting
Studying a new sedation combo for afib treatment
This trial tests a mild sedation method using remimazolam and fentanyl during a procedure called pulsed-field ablation for atrial fibrillation (afib). It aims to find a safe and effective way to keep you comfortable without deep sedation.
PragueAges 18 years+ - NCT07728539Recruiting
Comparing a faster ablation method for atrial fibrillation
This study compares a newer, faster type of ablation (high-power short-duration) with the standard approach for treating atrial fibrillation. The goal is to see which method is safer and more effective at restoring a normal heart rhythm.
MoscowAges 18–70 - NCT03642509Recruiting
Compare a heart procedure to blood-thinner pills for stroke prevention
This trial studies whether closing off part of the heart (the left atrial appendage) can prevent stroke as well as long-term newer blood-thinner pills. It may help people with atrial fibrillation who recently had a stroke or a warning stroke (TIA).
Aarhus, Central JutlandAges 18 years+ - NCT03912324Recruiting
CT-guided heart imaging to guide treatment for atrial fibrillation
This trial studies whether using a special CT scan map of the heart muscle thickness can help doctors choose the best strategy during a cryoballoon procedure for paroxysmal atrial fibrillation. It may help improve effectiveness by tailoring treatment instead of using a standard approach.
SeoulAges 20–80 - NCT04529785Recruiting
Tested added ethanol vein treatment during repeat atrial fibrillation ablation
This trial compares two ways to help stop atrial fibrillation during a repeat procedure: standard vein isolation only versus standard isolation plus an added medicine (ethanol) into the vein of Marshall. It aims to see whether the added step improves results when atrial fibrillation returns after a previous successful treatment.
Bruges, Please SelectAges 18 years+ - NCT04606693Recruiting
Screening for sleep apnea before heart rhythm ablation
This study looks at whether checking for sleep apnea (breathing pauses during sleep) and treating it helps people prepare for atrial fibrillation ablation. It may help by improving outcomes for patients with atrial fibrillation who keep having episodes despite medication.
Madrid, MadridAges 18 years+ - NCT04696081Recruiting
Atrial fibrillation treatment in people with active cancer
This trial studies atrial fibrillation (an irregular heartbeat) in adults who have active cancer. It looks at people whose atrial fibrillation started after their cancer diagnosis or returned after cancer diagnosis.
Caen, NormandyAges 18 years+ - NCT04715425Recruiting
Surgery vs catheter procedure for persistent atrial fibrillation
This trial compares two ways to treat persistent atrial fibrillation: a minimally invasive surgery approach versus a catheter ablation. It may help people find the most effective option to reduce ongoing abnormal heart rhythm and avoid repeat procedures.
AmsterdamAges 18–80 - NCT04823299Recruiting
Atrial fibrillation ablation using two different energy types
This trial tests whether one ablation approach works better than another for paroxysmal (intermittent) atrial fibrillation by targeting the heart’s “triggers” and “substrate” (where the rhythm problem is). If you qualify, you’ll be randomly assigned to one of two ablation energy methods during a pulmonary vein isolation procedure.
Ottawa, OntarioAges 18 years+ - NCT07523620Recruiting
Heart rhythm procedure with left atrial appendage closure
This trial tests a procedure that closes off a small pouch in the heart (left atrial appendage) while also treating irregular heartbeat (atrial fibrillation) with a catheter ablation procedure. The goal is to reduce your stroke risk and treat your symptoms without needing blood thinners long-term.
Brussels, B CAP RAges 18 years+ - NCT05021601Recruiting
Ablation method comparison for rheumatic valve and ongoing AF
This study compares two heart procedures—targeting one or both upper heart chambers versus only the left upper chamber—to treat people with ongoing atrial fibrillation caused by rheumatic mitral valve disease. It aims to see which approach works better and is safer for restoring normal rhythm.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05115214Recruiting
Device test for treating irregular heartbeat with AF ablation
This trial studies a heart procedure using the Affera SpherePVI system to treat paroxysmal (comes and goes) or persistent atrial fibrillation. It’s for people who still have symptoms despite at least one anti-arrhythmia medicine, and who are good candidates for catheter ablation.
PragueAges 18–75 - NCT05144503Recruiting
Test of a new catheter procedure for irregular heart rhythm
This study checks how safe and effective a special catheter procedure (SpherePVI) is for treating paroxysmal (comes and goes) or persistent atrial fibrillation. You may be considered if your atrial fibrillation keeps returning and you’ve already tried at least one medication but it didn’t work or you couldn’t tolerate it.
VilniusAges 18–75 - NCT05266144Recruiting
Catheter ablation for non-valvular atrial fibrillation
This trial studies catheter ablation, a procedure that targets heart rhythm triggers, for people with atrial fibrillation (an irregular heartbeat). It may help improve rhythm control, but you must meet specific heart and testing requirements and avoid certain conditions.
Beijing, Beijing MunicipalityAges 18–80 - NCT05371405Recruiting
Using computer learning to improve care for atrial fibrillation patients
This study uses machine learning (computer pattern-finding) to better understand atrial fibrillation and guide care around the time of an ablation procedure. It may help refine how doctors treat certain AF patients based on their heart patterns.
Stanford, CaliforniaAges 22–80 - NCT05549752RecruitingPhase 3
Flecainide vs amiodarone to treat fast heart rhythm in ER
This trial compares two medicines—flecainide and amiodarone—to help restore normal rhythm during an emergency visit for paroxysmal atrial fibrillation (a-fib). It’s aimed at people who also have coronary artery disease but no ongoing (residual) heart ischemia, and who have enough heart pumping strength.
AthensAges 18–85
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Paroxysmal Atrial Fibrillation trials by city
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Paroxysmal Atrial Fibrillation trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for paroxysmal atrial fibrillation?
- Yes. Clin2 currently lists 183 recruiting paroxysmal atrial fibrillation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a paroxysmal atrial fibrillation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a paroxysmal atrial fibrillation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.