Clinical trials
Participation clinical trials
Below are recruiting participation clinical trials, each written for real people, not researchers. We’re tracking 2,283 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07749768RecruitingPhase 1
Oral drug for ulcerative colitis safety study
This study tests an investigational oral drug for ulcerative colitis. It is an early-stage trial to check safety and how the drug is processed by the body in both healthy volunteers and patients with active ulcerative colitis.
Miami, FloridaAges 18–55 - NCT07758101RecruitingPhase 1
Study of a new medicine for ulcerative colitis
This trial tests a new medicine to see if it's safe for people with moderate to severe ulcerative colitis. It also tests the medicine in healthy volunteers to check for side effects. If you have ulcerative colitis, this might offer a new treatment option.
Hangzhou, ZhejiangAges 18–55 - NCT07753993RecruitingPhase 3
Study of elecoglipron for chronic kidney disease
This trial tests an investigational medicine called elecoglipron for people with chronic kidney disease. It aims to see if it can improve kidney health compared to a placebo (inactive pill) and may be an option for those already on standard blood pressure and kidney protective medications.
Huntsville, AlabamaAges 18 years+ - NCT07750158RecruitingPhase 3
Zanzalintinib for colorectal cancer with residual tumor dna
This trial is testing a new drug (zanzalintinib) alone or with pembrolizumab to see if it can stop cancer from coming back in people with colorectal cancer who have no visible cancer on scans but still have tumor DNA in their blood.
Council Bluffs, IowaAges 18 years+ - NCT07755410RecruitingPhase 2
Investigational ADHD treatment for adults
This study tests an investigational medication for adults with attention deficit hyperactivity disorder (ADHD). It aims to see if this new drug helps reduce ADHD symptoms compared to a placebo.
Little Rock, ArkansasAges 18–65 - NCT07752407RecruitingPhase 3
Heartburn relief study for people with non-erosive GERD
This study tests a new medicine called vonoprazan to see if it can reduce episodes of heartburn in people who have GERD but no damage to their esophagus. It compares the medicine to a placebo (a pill with no active ingredient) over 24 weeks.
Mentor, OhioAges 18 years+ - NCT07748403RecruitingPhase 1/Phase 2
Gene therapy for Wilson disease
This trial is testing an experimental gene therapy called PM577 that aims to fix the faulty gene causing Wilson disease. It might offer a new treatment option that could reduce or replace the need for daily medications.
New Haven, ConnecticutAges 12 years+ - NCT07743671RecruitingPhase 3
Engasertib for frequent nosebleeds from HHT
This trial tests an experimental pill, engasertib, to reduce frequent nosebleeds in adults with a rare blood vessel condition called hereditary hemorrhagic telangiectasia (HHT). Participation may help if you have moderate to severe nosebleeds and need iron or blood transfusions.
Chicago, IllinoisAges 18 years+ - NCT07743463RecruitingPhase 3
Daily pill for weight loss in adults with excess weight or weight-related health issues
This study tests a once-daily pill called ASC30 to help adults with obesity or overweight who also have conditions like high blood pressure, sleep apnea, or heart disease lose weight. The pill may work by affecting appetite and blood sugar, and the study aims to see how effective and safe it is.
Birmingham, AlabamaAges 18 years+ - NCT07742735RecruitingPhase 3
Study of apraglutide for short bowel syndrome with intestinal failure
This study tests a new medicine called apraglutide, given as a shot, to see if it can help adults with short bowel syndrome and intestinal failure reduce their need for intravenous nutrition (parenteral support). The study compares apraglutide to a placebo (a shot with no medicine) to check if it is safe and effective.
Los Angeles, CaliforniaAges 18 years+ - NCT07746817RecruitingPhase 1
Study of a new drug for eczema
This study tests a new drug called BYN-001 in two groups: healthy people and people with moderate to severe eczema (atopic dermatitis). The goal is to see if the drug is safe and how well it works.
Melbourne, VictoriaAges 18–55 - NCT07748624RecruitingPhase 2
Testing a new drug for people with VEXAS
This study tests an investigational drug called arumakimig (MAS825) in people with VEXAS, a rare genetic condition that causes inflammation. The trial checks if the drug helps control symptoms and improve quality of life.
Yokohama, KanagawaAges 18 years+ - NCT07743580RecruitingPhase 3
Secutrelvir for covid-19 patients at high risk
This trial tests a new antiviral pill, secutrelvir, for people with mild to moderate covid-19 who are at higher risk of getting seriously ill. It aims to see if the drug can prevent hospitalization or severe disease.
Coral Gables, FloridaAges 12 years+ - NCT07746544RecruitingPhase 3
Secutrelvir for treating covid-19 in adolescents and adults
This study tests an experimental oral antiviral, secutrelvir, for people with mild to moderate COVID-19 who are not sick enough to need hospital care. The medicine aims to reduce symptoms and help you recover faster.
Multiple LocationsAges 12–74 - NCT07743450RecruitingPhase 3
Daily oral medication for weight loss in adults with obesity and type 2 diabetes
This study tests a once-a-day pill for adults who are overweight or have obesity and also have type 2 diabetes. The goal is to see if the medication helps with weight loss and improves blood sugar control.
Birmingham, AlabamaAges 18 years+ - NCT07749586RecruitingPhase 1/Phase 2
Study of ARV-6723 alone or with pembrolizumab for advanced solid tumors
This trial tests an experimental drug called ARV-6723, alone or with another drug called pembrolizumab, for people with advanced solid tumors that have not responded to other treatments. The goal is to see if these combinations can help shrink tumors or slow their growth.
New York, New YorkAges 18 years+ - NCT07746583Recruiting
Switching from ustekinumab to guselkumab for psoriasis
This study is testing a medicine called guselkumab (Tremfya) for people with psoriasis who are already taking another biologic medicine, ustekinumab, but need to switch. The goal is to see how well guselkumab works in real-world use.
BudapestAges 18 years+ - NCT07746713RecruitingPhase 1
Study of a new drug for advanced prostate cancer that has spread and progressed
This study tests a new drug called JNJ-98768111 in people with advanced prostate cancer that has spread and is no longer responding to current hormone-based treatments. It aims to see if the drug is safe and effective, and participants will receive the study drug while continuing some standard hormone therapy.
Sarasota, FloridaAges 18 years+ - NCT07743151RecruitingPhase 1
Study of the drug MK-1406 in healthy participants
This trial is testing a new drug, MK-1406, in healthy volunteers to see how the body processes it. It helps researchers find the right dose and check for side effects before testing in patients.
Hollywood, FloridaAges 18–64 - NCT07745907RecruitingPhase 1
A first-in-human study of a new drug in healthy Chinese and Japanese adults
This trial tests a single dose of an investigational drug called AMG 691 in healthy Chinese and Japanese volunteers to see how it is processed by the body and how safe it is. This is an early-phase study, so it may help make future treatments safer for people of similar backgrounds.
Las Vegas, NevadaAges 18–60 - NCT07743268Enrolling by invitationPhase 1/Phase 2
Personalized gene therapy for ALS linked to TARDBP
This trial tests a personalized medicine approach for people with ALS caused by changes in the TARDBP gene. The treatment uses a custom-made molecule to target the genetic cause and may help slow the disease.
St Louis, MissouriAges Any age - NCT07742917Recruiting
Personalized lifestyle program for weight management
This program tests a personalized lifestyle plan designed to help you manage your weight and improve your health. It uses your genetic information and other personal data to tailor the support you receive.
Abu DhabiAges 25–50 - NCT07749482Recruiting
Caregiver support program to prevent elder mistreatment
This study tests a way to support family caregivers of older adults who get medical care at home. It aims to reduce the risk of elder mistreatment by helping caregivers cope with stress and get the support they need.
Galveston, TexasAges 18 years+ - NCT07746167Recruiting
Pupil response study in healthy adults
This study looks at how your pupils react to light in healthy people. It may help doctors understand normal eye responses, which could improve future eye tests.
Washington D.C., District of ColumbiaAges 18–60
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Common questions
- Are there clinical trials for participation?
- Yes. Clin2 currently lists 2,283 recruiting participation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a participation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a participation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.