Clinical trials
Participation clinical trials
Below are recruiting participation clinical trials, each written for real people, not researchers. We’re tracking 2,237 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07300189RecruitingPhase 1
Testing TLC-1180 in healthy volunteers
This study tests a new medicine called TLC-1180 in healthy volunteers to see how it works in the body. It's a first step to find a safe dose before studying it in people with illness.
AucklandAges 18–55 - NCT06471829RecruitingPhase 2
Study of Lu AG13909 for adults with Cushing's disease
This study tests a new medicine called Lu AG13909 for adults with Cushing's disease caused by a pituitary tumor. It aims to see if the medicine can lower cortisol levels and help control the disease.
Ann Arbor, MichiganAges 18–70 - NCT07515014RecruitingPhase 2
Testing E6742 in Systemic Lupus Erythematosus
This study tests a new medicine called E6742 to help people with systemic lupus erythematosus (SLE), an autoimmune disease where the body attacks its own tissues. Researchers want to see if this drug can reduce lupus symptoms and disease activity.
Bengbu, AnhuiAges 18–75 - NCT05897320RecruitingPhase 3
Eptinezumab trial for kids with episodic migraine
This Phase 3 study tests eptinezumab to reduce migraine attacks in children who have episodic migraine (not daily chronic migraine). It may help by lowering the number of headache days and migraine days over time. You must complete a headache diary during screening to be considered.
Stamford, ConnecticutAges 6–17 - NCT07223593RecruitingPhase 3
Orforglipron for peripheral artery disease with leg pain
This trial tests a new oral medication called orforglipron to see if it can improve walking distance in people with peripheral artery disease (PAD) who have leg pain when walking. It may be a good option if you have PAD and your walking is limited by leg cramping, not other health issues.
Birmingham, AlabamaAges 18 years+ - NCT06937099RecruitingPhase 3
Testing two drugs for Crohn's with weight issues
This trial tests two study drugs, mirikizumab and tirzepatide, in people with moderate to severe Crohn's disease who also have overweight or obesity. The goal is to see if these treatments can help control Crohn's symptoms and inflammation.
Dothan, AlabamaAges 18–70 - NCT07213804RecruitingPhase 3
Study of sofetabart mipitecan for ovarian cancer
This trial tests a new drug called sofetabart mipitecan for people with ovarian cancer that has come back after treatment. It is for those whose cancer is either resistant to platinum chemo (Part A) or sensitive to it (Parts B and C). The study will see if the drug can help shrink or slow the cancer.
Birmingham, AlabamaAges 18 years+ - NCT07730554RecruitingPhase 2
Study of injections for forehead and frown lines
This trial tests an injectable treatment for moderate to severe forehead lines and frown lines in adults. It aims to see if the injections can safely reduce the appearance of these lines.
Newport Beach, CaliforniaAges 18 years+ - NCT07550946RecruitingPhase 1
How Food and Stomach Acid Medicine Affect a New Drug
This study tests how a new experimental drug (VRN101099) works in your body when taken with food and with a common stomach acid medication. Researchers want to understand how these factors change how much drug reaches your bloodstream, which helps them figure out the right dose for future patients.
Melbourne, VictoriaAges 18–65 - NCT07455851RecruitingPhase 1/Phase 2
Studying a new drug combo for relapsed or refractory multiple myeloma
This trial tests whether REGN17372 plus linvoseltamab is safe for people with multiple myeloma that has come back or not responded to prior treatments. You may join if you have tried at least 3 other therapies.
Randwick, New South WalesAges 18 years+ - NCT07503873RecruitingPhase 2
Study of ublituximab injection for multiple sclerosis
This trial tests a new way to give the drug ublituximab (an injection under the skin) to people with relapsing multiple sclerosis. It compares different injection sites and a special auto-injector device to see how the body absorbs the drug and if it's safe.
BihaćAges 18–65 - NCT05006716RecruitingPhase 1/Phase 2
Testing a new drug for certain B-cell blood cancers
This Phase 1/2 trial studies the safest dose and then effectiveness of BGB-16673 in people with specific B-cell malignancies. It may help by targeting cancer cells in these blood cancers, especially after other treatments like BTK inhibitors.
Birmingham, AlabamaAges 18 years+ - NCT07734844RecruitingPhase 3
New vs existing treatment for diabetic macular edema
This study compares a new medication, tabirafusp tedromer, to an existing treatment, aflibercept, for people with diabetic macular edema (swelling in the back of the eye from diabetes). It may help if your DME hasn't improved or you're looking for a new option.
Glendale, CaliforniaAges 18 years+ - NCT07059845RecruitingPhase 2
Studying mirvetuximab combos for ovarian cancer
This trial tests multiple combinations of the drug mirvetuximab soravtansine with other treatments for people with ovarian cancer. It aims to see how well these combos work and what side effects they cause.
La Jolla, CaliforniaAges 18 years+ - NCT07613307RecruitingPhase 3
Study of a new pill for type 2 diabetes during Ramadan fasting
This study tests an oral medication called orforglipron to see if it safely helps people with type 2 diabetes manage their blood sugar while they fast during Ramadan. You may be a good fit if you are planning to fast and your diabetes is not too severe.
AgraAges 18–65 - NCT07598396RecruitingPhase 2
Mosunetuzumab for systemic lupus erythematosus treatment
This study tests a new drug called mosunetuzumab in people with systemic lupus erythematosus (SLE), a disease where the immune system attacks the body's own tissues. The drug is designed to help control the immune response and reduce lupus symptoms, including kidney involvement if present.
Salvador, Estado de BahiaAges 18 years+ - NCT05920356RecruitingPhase 3
Tested KRAS-targeted sotorasib plus chemo vs pembrolizumab plus chemo
This Phase 3 trial tests whether sotorasib plus standard chemotherapy works better than pembrolizumab (an immunotherapy) plus standard chemotherapy as first treatment for certain advanced lung cancers. It may help people whose tumors have a KRAS G12C mutation and that do not show PD-L1 on testing.
Santa Barbara, CaliforniaAges 18–100 - NCT07620392RecruitingPhase 2
Long-Term Safety Study of Afimkibart for Rheumatoid Arthritis
This is a follow-up study for people who already completed a previous trial testing afimkibart (an experimental drug) for rheumatoid arthritis. It checks whether the drug continues to work safely and effectively over a longer period.
Tamarac, FloridaAges 18 years+ - NCT07429266RecruitingPhase 3
Study of sapablursen for phlebotomy-dependent polycythemia vera
This trial tests an investigational drug called sapablursen for people with polycythemia vera who still need frequent phlebotomies. The goal is to see if the drug can reduce the need for blood removal and help control the disease safely.
Miami, FloridaAges 18 years+ - NCT07541287RecruitingPhase 2
JADE101 for IgA Nephropathy Kidney Disease
This study tests whether JADE101, a new medicine, can help slow kidney damage in people with IgA nephropathy (a type of kidney disease caused by immune system problems). You'll take it alongside your current blood pressure medications for about 48 weeks.
Chula Vista, CaliforniaAges 18–60 - NCT07665723RecruitingPhase 1
Study of afimkibart and other medicines in ulcerative colitis
This study looks at how afimkibart affects the way your body processes certain other medicines. It is for people with moderate to severe ulcerative colitis and helps researchers understand how to use this treatment safely.
Chula Vista, CaliforniaAges 18–60 - NCT07612267RecruitingPhase 4
Mirikizumab Levels in Breast Milk During Treatment
This study measures how much of the medication mirikizumab passes into breast milk when mothers take it for their approved medical condition. The goal is to understand if it's safe for breastfeeding infants when mothers are receiving this treatment.
Glenview, IllinoisAges 3 weeks+ - NCT06785636RecruitingPhase 1/Phase 2
New drug combination for advanced prostate cancer
This study tests a new drug (pocenbrodib) alone or combined with another hormone therapy (darolutamide) for men with advanced prostate cancer that has spread. It is for those who have already tried Pluvicto and one other hormone therapy, but not yet chemotherapy.
Fountain Valley, CaliforniaAges 18 years+ - NCT06678659RecruitingPhase 1/Phase 2
Study of REC-1245 for advanced solid tumors and lymphoma
This trial tests a new drug, REC-1245, for people with advanced solid tumors or certain lymphomas that have not responded to standard treatments. The goal is to see if the drug can shrink tumors or slow disease progression.
Duarte, CaliforniaAges 12 years+
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Common questions
- Are there clinical trials for participation?
- Yes. Clin2 currently lists 2,237 recruiting participation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a participation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a participation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.