Clinical trials
Pediatric ALL clinical trials
Below are recruiting pediatric all clinical trials, each written for real people, not researchers. We’re tracking 1,359 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05734066RecruitingPhase 1/Phase 2
Lurbinectedin drug study for young people with Ewing sarcoma
This trial tests lurbinectedin, a cancer medicine, by itself (no other drugs) in children and young adults whose Ewing sarcoma has come back or did not respond to prior treatment. It aims to see how safe the drug is and whether it can help control the cancer.
Los Angeles, CaliforniaAges 2–30 - NCT05732779Recruiting
App-based check-ins to help teens take transplant medicines
This study tests a phone app that uses video check-ins (called directly observed therapy) to help adolescent heart-transplant patients take their immunosuppression medicines as prescribed. It may help reduce missed doses, which is important for protecting the transplanted heart.
Coral Gables, FloridaAges 10–21 - NCT00616317Recruiting
Study for children with antiphospholipid syndrome and blood clots
This study is for children who have antiphospholipid syndrome (APS) and a history of blood vessel clots. Researchers want to learn more about APS in pediatric patients who have specific blood test signs and clot history.
Sacramento, CaliforniaAges 1 minute–18 years - NCT05549258RecruitingPhase 2
Inebilizumab for children with NMOSD who had recent relapses
This trial studies whether inebilizumab can reduce illness activity in children with neuromyelitis optica spectrum disorder (NMOSD), a condition that can cause attacks affecting the eyes and spinal cord. It focuses on kids who have had recent relapses, meaning symptoms came back or worsened.
La Jolla, CaliforniaAges 2–17 - NCT05707949Enrolling by invitationPhase 3
Long-term safety study of atogepant for kids with migraine
This trial studies the long-term safety (side effects over time) of atogepant tablets in children and teens with migraine. It may help families understand whether the medicine is safe for longer use in ages 6 to 17.
Huntsville, AlabamaAges 6–17 - NCT05682378RecruitingPhase 3
Long-term follow-up for inclisiran in young people with inherited high cholesterol
This study follows people with HeFH or HoFH (inherited high cholesterol) who previously took inclisiran in specific pediatric ORION studies. It mainly checks long-term safety and how well the treatment continues to be tolerated over time.
Boca Raton, FloridaAges 2–100 - NCT05679622Recruiting
Stool transplant study for children with mild to moderate ulcerative colitis
This trial studies whether transferring healthy stool bacteria into the gut (fecal microbiota transplantation, or FMT) can improve symptoms in children with ulcerative colitis. It may help by changing gut bacteria, especially for children who are newly diagnosed or who didn’t respond to standard treatments.
WuhanAges 2–16 - NCT05691608Recruiting
Tumor genetics for personalized pediatric cancer treatment
This trial studies the genetic makeup of your tumor to find personalized treatment options, especially if standard treatments have not worked. It aims to match you with experimental treatments that target your cancer's specific changes.
Amiens, FranceAges 6–25 - NCT05674643Recruiting
Gastric testing during children’s surgery
This trial studies how the stomach is working in children around the time of surgery. It may help improve how doctors assess and manage stomach function to make surgery safer and more comfortable.
Boston, MassachusettsAges 2–18 - NCT05656378Recruiting
Storing samples to study how the body interacts with microbes
This study creates a storage bank of biological samples like blood, stool, and tissue. Researchers will use these samples to learn how the body interacts with the natural microbes that live in and on us, which may help improve treatments for many diseases.
Bethesda, MarylandAges Any age - NCT05642455RecruitingPhase 1/Phase 2
Study of a new treatment for certain childhood cancers
This Phase 1/2 study tests a new therapy for children and young adults with specific types of cancer that have been treated with chemotherapy before. It may help by targeting cancer features in the tumor and using your immune system in a controlled way.
Palo Alto, CaliforniaAges 2–21 - NCT05673551Enrolling by invitation
VR during at-home burn dressing changes for kids
This trial tests whether virtual reality (VR) can help children feel better during daily burn dressing changes at home. It will study comfort and pain around the first time you do dressings after leaving the hospital.
Columbus, OhioAges 6–17 - NCT05658731Recruiting
Radiation planning study to protect thinking in children
This study compares how radiation is planned to see whether it better protects thinking and memory in children and young adults. It may help future patients by learning which planning approach leads to better cognitive (thinking) outcomes.
Washington D.C., District of ColumbiaAges 1–26 - NCT05645523RecruitingEarly Phase 1
ICG dye mapping to find lymph nodes in some childhood tumors
This early study tests using a special dye (indocyanine green, or ICG) to help surgeons find the correct “sentinel” lymph nodes during surgery in children with certain suspected tumors. If successful, it may improve how doctors remove and check lymph nodes while reducing the chance of missing important areas.
Chicago, IllinoisAges Up to 20 years - NCT05645718RecruitingPhase 2
Chemo plus targeted antibodies for relapsed childhood B-ALL
This Phase 2 study tests a combination treatment for children, teens, or young adults whose B-cell acute lymphoblastic leukemia (B-ALL) has come back or did not respond to initial therapy. It may help patients who cannot safely receive certain standard medicines like anthracyclines or who cannot tolerate PEG-asparaginase.
Houston, TexasAges 1–25 - NCT05645224Enrolling by invitation
Virtual reality for pain and anxiety during laser skin treatment
This study tests whether using virtual reality (VR) during a laser procedure for a skin condition helps children and teens feel less pain and anxiety. If you are having your first laser treatment, you might be able to use a VR headset to distract you during the procedure.
Columbus, OhioAges 5–25 - NCT05611801RecruitingPhase 3
Study medicine for children with hemophilia A or B
This trial tests a study medicine (marstacimab) for children with severe hemophilia A or B, to see if it can help prevent or reduce bleeding episodes. It may be an option for children who do not have certain other health conditions.
Salt Lake City, UtahAges 1–17 - NCT05609630RecruitingPhase 3
Testing two medicines for active systemic juvenile arthritis
This Phase 3 trial studies how well upadacitinib (a pill) and tocilizumab (a shot/IV medicine) improve symptoms and inflammation in children with active systemic juvenile idiopathic arthritis (sJIA). It also looks at side effects and how these medicines move through the body.
Phoenix, ArizonaAges 1–17 - NCT05609916Recruiting
CBT therapy to help kids stop OCD medicine
This trial studies whether adding structured talk therapy (CBT) can help some children with obsessive-compulsive disorder (OCD) reduce and potentially stop their OCD medicine. It’s designed for kids who are still having meaningful symptoms despite being on an OCD medication long enough.
Houston, TexasAges 7–17 - NCT05633693Recruiting
Exercises to help children with fainting and blood-pressure drops
This study tests whether teaching special standing/balance movements can reduce fainting episodes in children who have recurring vasovagal fainting or certain forms of POTS. It may help your child feel more stable when standing and improve symptoms, while researchers measure balance and “counterpressure” responses during the tests.
Burnaby, British ColumbiaAges 6–18 - NCT05577754RecruitingPhase 2
Trial tests alpelisib for MCAP with PIK3CA mutations
This Phase 2 study tests alpelisib in children and adults with MCAP, a condition caused by a specific PIK3CA gene mutation. The goal is to see if the treatment is effective and safe, while carefully monitoring blood sugar and organ function.
AmiensAges 2–40 - NCT05553899Recruiting
PET-MRI scans for monitoring children’s brain tumor return
This study checks whether a special scan called PET-MRI can better tell if a child’s brain tumor has come back after treatment. It may help doctors decide faster and more accurately when changes seen on regular MRI are true tumor recurrence.
Sheffield, South YorkshireAges 8–18 - NCT05544019RecruitingPhase 1
Testing an investigational drug for mature B-cell cancers
This early (Phase 1) study tests SGR-1505, an experimental treatment, in people with certain mature B-cell cancers. It’s mainly designed to see how the drug works in the body and to check safety, and it may offer an option if standard treatments aren’t enough.
Gilbert, ArizonaAges 18 years+ - NCT05509777RecruitingPhase 3
Mirikizumab for children with active Crohn’s disease
This study tests mirikizumab to reduce inflammation and symptoms in children with Crohn’s disease that is currently active. It may help if your Crohn’s has not improved enough (or stopped working) with at least one other Crohn’s medicine.
Los Angeles, CaliforniaAges 2–17
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Common questions
- Are there clinical trials for pediatric all?
- Yes. Clin2 currently lists 1,359 recruiting pediatric all studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pediatric all trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pediatric all trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Beyond the search
We also like to point to nonprofits doing real good in this area. We aren’t affiliated with them — we just admire the work.
- Children’s Oncology Support FundChildren with cancer and the families caring for them.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.