Clinical trials
Pediatric Cancer clinical trials
Below are recruiting pediatric cancer clinical trials, each written for real people, not researchers. We’re tracking 149 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07528547Recruiting
Imaging Tools for Kids Undergoing Radiation Therapy
This study tests new imaging technology (Hypersight and Ethos systems) to help doctors better see and target radiation therapy in children and teens with cancer. The goal is to improve how accurately radiation is delivered while reducing side effects.
Toronto, OntarioAges Up to 18 years - NCT05106296RecruitingPhase 1
Chemo-immunotherapy with ibrutinib and indoximod for pediatric brain tumors
This Phase 1 study tests a combination treatment (ibrutinib plus indoximod along with chemotherapy) for children with brain tumors that have come back or are hard to treat. It may help shrink active tumor or control the disease when standard treatments can’t cure it.
Augusta, GeorgiaAges 3–25 - NCT04717349Recruiting
Study collects health information for kids’ and teens’ gynecology concerns
This is a research study that gathers information about pediatric and adolescent gynecology conditions. It may help researchers better understand these issues by learning about symptoms, care, and outcomes—without requiring a specific treatment.
Bethesda, MarylandAges 1 day–100 years - NCT07305090Recruiting
Gut GVHD biomarker study for transplant patients
This trial aims to develop a test using multiple biomarkers to predict how well patients will respond to treatment for acute graft-versus-host disease (GVHD) affecting the gut. It focuses on patients who are receiving an allogeneic stem cell transplant.
Bologna, BolognaAges 12 years+ - NCT05691608Recruiting
Tumor genetics for personalized pediatric cancer treatment
This trial studies the genetic makeup of your tumor to find personalized treatment options, especially if standard treatments have not worked. It aims to match you with experimental treatments that target your cancer's specific changes.
Amiens, FranceAges 6–25 - NCT06838689Recruiting
Comparing ways to involve people in pediatric, cancer, and serious illness research
This study compares two different methods for including patients, families, and clinicians in qualitative research about pediatric mental health, cancer screening, or serious illness. You can help by sharing your experiences and perspectives.
Hanover, New HampshireAges 18 years+ - NCT04715191RecruitingPhase 1
CAR T therapy for GPC3-positive pediatric solid tumors
This Phase 1 study tests a customized immune-cell treatment (CAR T cells) made to recognize GPC3, a marker found on some tumors. It’s designed for children and young people whose solid tumors have not been cured by standard treatment and who can safely receive this therapy.
Houston, TexasAges 1–21 - NCT03911388RecruitingPhase 1
HSV G207 for Children with Recurrent Cerebellar Brain Tumors
This trial is testing a virus called HSV G207, which is injected directly into the tumor, to treat children and young adults with a type of brain tumor in the cerebellum that has come back or not responded to standard treatments.
Birmingham, AlabamaAges 3–22 - NCT05023785Recruiting
Lifestyle program for cancer survivors with early heart strain
This trial tests a structured lifestyle and exercise change program for young people who finished cancer treatment and have signs of early heart weakness. The goal is to improve heart health and lower the chance of heart failure later.
Toronto, OntarioAges 18–45 - NCT07490548Enrolling by invitation
Lifestyle, mental health, and quality of life in childhood cancer survivors
This trial looks at how following a healthy lifestyle affects mental well-being and quality of life in children and teens who have finished cancer treatment. It is meant for those who are now coming back for follow-up visits.
CuencaAges 3–17 - NCT07129317Recruiting
Pediatric radiation therapy registry
This study collects information from children and young adults who are getting radiation therapy to help improve future treatments. It looks at how radiation affects the body over time.
Washington D.C., District of ColumbiaAges birth–26 years - NCT06397027RecruitingPhase 1
Ziftomenib, venetoclax, and azacitidine for pediatric leukemia
This trial tests a new drug combination (ziftomenib, venetoclax, and azacitidine) in children and young adults with acute leukemia that has come back or not responded to treatment. It may help if your child's leukemia has certain genetic changes (like KMT2A, NPM1, or NUP98).
Houston, TexasAges 2–21 - NCT05658731Recruiting
Radiation planning study to protect thinking in children
This study compares how radiation is planned to see whether it better protects thinking and memory in children and young adults. It may help future patients by learning which planning approach leads to better cognitive (thinking) outcomes.
Washington D.C., District of ColumbiaAges 1–26 - NCT05350748Recruiting
MDS study using detailed tests on blood and bone marrow
This study carefully evaluates people with myelodysplastic syndromes (MDS) and closely related blood disorders using detailed medical, blood, and bone marrow testing. The goal is to better understand these conditions and how they progress, which may help guide future care.
Bethesda, MarylandAges 1 day–120 years - NCT06300515Recruiting
Exercise and counseling for young stem cell transplant patients
This study tests whether exercise and health counseling can help children and young people recovering from a stem cell transplant for cancer. Participants will be assigned to either the exercise program or standard care, and the study will see how it affects their recovery and quality of life.
Madrid, MadridAges 4–21 - NCT05372640RecruitingPhase 1
Drug combo trial for rare cancers with shared NUT features
This Phase 1 trial tests the safety and early signs of effectiveness of combining two anti-cancer drugs (ZEN003694 and abemaciclib) in teens and adults with metastatic or unresectable NUT carcinoma, breast cancer, and other solid tumors. It may help by finding a safer dose and whether the drug combination can shrink or control tumors that do not respond to standard treatments.
Los Angeles, CaliforniaAges 12 years+ - NCT06074666Recruiting
Parent training to boost medication adherence in pediatric leukemia
This study tests a new parenting program to help improve how well children with leukemia take their oral medications at home. The program focuses on building helpful skills for giving daily medicine.
Buffalo, New YorkAges 3–9 - NCT07575815Recruiting
Understanding Anxiety in Children During Radiation Therapy
This study watches how children feel anxious before and during radiation therapy treatment at MD Anderson. By understanding anxiety patterns, doctors hope to better support children and families going through this experience.
Houston, TexasAges 2–12 - NCT03739827Recruiting
Study rare solid tumors and collect your health samples
This study follows people (and sometimes family members) connected to rare solid tumors and collects health information and samples (biospecimens). It helps researchers understand how these cancers develop and builds resources for future research, which may benefit you by contributing to better tailored care for rare cancers.
Bethesda, MarylandAges 4 weeks+ - NCT06969742Recruiting
Mental health program for young cancer survivors and caregivers
This trial tests a program to help improve mental health and quality of life for teenagers and young adults who have had a solid tumor cancer, and for their caregivers. It focuses on those recently finished treatment or still in treatment, and aims to provide supportive counseling.
Goyang-si, Gyonggi-doAges 10–24 - NCT04897321RecruitingPhase 1
CAR T therapy for children with B7-H3 solid tumors
This early-phase study tests a lab-made immune therapy (CAR T cells) made from your own cells to treat children’s solid tumors that have a specific marker called B7-H3. It is designed for kids whose cancer has come back or did not respond to standard treatment, aiming to shrink tumors and keep the therapy safe.
Memphis, TennesseeAges Up to 21 years - NCT05740839Recruiting
High-intensity exercise program for young brain tumor survivors
This pilot study tests whether a high-intensity interval exercise routine is safe and doable for young adult survivors of pediatric brain tumors. It may help you improve fitness and quality of life while researchers closely monitor safety.
Boston, MassachusettsAges 18–45 - NCT07662018Recruiting
Study of stem cell transplant after chemo for children with germ cell tumors
This study looks at how well a stem cell transplant works after a specific combination of chemotherapy drugs (gemcitabine, docetaxel, melphalan, and carboplatin) in children and young adults up to age 21 whose germ cell tumors have come back or not responded to treatment. It may help doctors understand who benefits most from this approach.
Houston, TexasAges 21 years+ - NCT06430788RecruitingPhase 2
Emapalumab for children with severe aplastic anemia
This trial tests whether a medication called emapalumab can help children with severe aplastic anemia, a condition where the bone marrow stops making enough blood cells. It combines emapalumab with standard immune-suppressing therapy to try to improve blood cell counts.
New York, New YorkAges birth–25 years
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Common questions
- Are there clinical trials for pediatric cancer?
- Yes. Clin2 currently lists 149 recruiting pediatric cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pediatric cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pediatric cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Beyond the search
We also like to point to nonprofits doing real good in this area. We aren’t affiliated with them — we just admire the work.
- Children’s Oncology Support FundChildren with cancer and the families caring for them.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.