Clinical trials
Periodontal Pocket clinical trials
Below are recruiting periodontal pocket clinical trials, each written for real people, not researchers. We’re tracking 25 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05533528Recruiting
Save gum tissue in surgery for severe periodontitis
This trial studies a way to preserve gum (periodontal) “granulation” tissue during surgical treatment for severe periodontitis (gum disease). It may help patients heal better after surgery, especially when deep gum pockets do not improve after non-surgical care.
MurciaAges 18 years+ - NCT06309719Recruiting
Hyaluronic acid and polynucleotides for gum disease treatment
This trial tests if a gel made from hyaluronic acid and polynucleotides can help repair gum damage in people with advanced gum disease. You may be eligible if you have deep pockets between your teeth and gums that haven't healed after standard cleaning.
LondonAges 18 years+ - NCT06522438Recruiting
Gel with Hyaluronic Acid for Gum Disease Treatment
This study tests whether a gel containing hyaluronic acid and octenidine can improve the results of standard deep cleaning for advanced gum disease. It may help reduce gum pocket depth and bleeding without the need for surgery.
LondonAges 18 years+ - NCT06958874Recruiting
Erythritol for gum pocket healing
This study tests if adding erythritol to standard gum treatment helps close deep gum pockets in people with advanced gum disease (periodontitis).
L’AquilaAges 35 years+ - NCT06980675Recruiting
Ozonized olive oil for gum disease treatment
This trial tests if a special ozonized olive oil gel can help treat deep gum pockets caused by periodontitis (advanced gum disease). If you have gum pockets that are 4 mm or deeper, this could be an option to reduce infection and improve healing.
Bari, BAAges 18 years+ - NCT05932017Enrolling by invitation
Compare two ways to see during gum surgery
This trial compares two tools surgeons use to see during gum (periodontal) surgery: magnifying loupes versus a videoscope. It may help improve how the procedure is done for people with more severe gum disease.
Dallas, TexasAges 18 years+ - NCT06624241Recruiting
Curcumin gel plus deep cleaning for Stage III gum disease
This trial tests a new gel made from curcumin (a natural substance found in turmeric) combined with a standard deep cleaning treatment for Stage III gum disease. The goal is to see if the gel helps reduce gum inflammation and improve healing.
Chieti, CHAges 18–80 - NCT07446127Recruiting
Adding Laser to Gum Disease Treatment
This trial tests adding a special laser (diode laser) to standard deep cleaning for gum disease. The goal is to see if the laser helps reduce infection and improve healing better than cleaning alone.
Afula, NorthAges 18 years+ - NCT05858411Recruiting
Biologic gum treatments added to non-surgical cleaning
This trial studies whether adding a biologic medicine to standard non-surgical gum (periodontal) treatment can improve deep gum pockets in certain bone defects. It may help people whose gum disease has specific “intrabony” defects, but you must meet several health and medication rules.
TiranaAges 18 years+ - NCT06490679Recruiting
Comparing a new air-polishing device to standard deep pocket cleaning
This trial tests if a special air-polishing device using erythritol powder is better than standard tools for cleaning deep gum pockets (7-10 mm). It aims to see which method works better without surgery, which could mean less discomfort and faster healing.
CairoAges 16–80 - NCT06123000Recruiting
Comparing two surgeries for gum disease
This study compares two types of gum surgery for people with advanced gum disease. It's designed to see which method works better for treating deep gum pockets and saving bone.
Florence, FIAges 18 years+ - NCT03997552Recruiting
Gum surgery options to help regenerate damaged gum bone
This trial compares two dental gum surgery approaches to see which better helps the gum and bone heal in people with periodontitis. It may help by improving the depth of gum pockets and supporting regrowth of damaged areas around teeth.
MurciaAges 18 years+ - NCT06428149Recruiting
Comparing gum surgery techniques for deep pockets
This study looks at three different ways to make cuts in the gums during surgery for deep pockets caused by gum disease. It aims to find which technique helps heal better and save more bone.
Murcia, MurciaAges 18–80 - NCT07327658Recruiting
Periodontal treatment and pocket depth changes
This trial looks at how much gum pocket depth decreases after standard gum disease treatment. It is for people with advanced periodontitis who are otherwise healthy.
Konya, KonyaAges 18–65 - NCT07587606Enrolling by invitation
Studying Healing Tissue in Deep Gum Pockets
This study examines how gum tissue heals in deep pockets that remain after standard gum disease treatment. Researchers will collect small samples of healing tissue to better understand gum disease and improve future treatments.
Roma, RomaAges 18–75 - NCT06505759RecruitingPhase 1
Bromelain gel vs. chlorhexidine for gum disease treatment
This trial tests if a gel made from bromelain (a pineapple enzyme) works as well as a standard antibiotic gel to treat gum pockets caused by periodontitis. It may offer a gentler option for patients with moderate gum disease.
Bengaluru, KarnatakaAges 30–50 - NCT07754253RecruitingPhase 1
Green tea extract for gum disease treatment
This trial tests a green tea extract (EGCG) as an add-on to standard gum disease treatment, delivered locally to the gums. It aims to see if this natural compound can help improve gum health more effectively than standard care alone.
Al Mansurah, Dakahlia GovernorateAges 25–60 - NCT07718932Recruiting
Healing gel for wisdom tooth extraction recovery
This trial tests a regenerative gel placed in the socket after wisdom tooth removal to improve healing. It may reduce pain, swelling, and speed up recovery.
ThessalonikiAges 18–35 - NCT07292870Recruiting
Biological treatments for deep gum bone defects
This trial tests whether biological agents can help heal deep gum bone defects that remain after standard non-surgical cleaning. It may be an option for people who still have deep pockets around their teeth and need a minimally invasive surgical procedure.
Leuven, Vlaams BrabantAges 18 years+ - NCT07722390Recruiting
Injection treatment for deep gum pockets
This study tests whether injecting a special substance made from your own blood can help treat deep gum pockets without surgery. It may be an option for people with advanced gum disease who have already had initial cleaning.
CairoAges Any age - NCT07574827Recruiting
Candida Fungus and Gum Disease in Syrian Patients
This study looks at whether a common fungus called Candida albicans is linked to chronic periodontitis (advanced gum disease). Researchers will examine gum samples from Syrian patients to understand this connection and may help improve gum disease treatment.
HomsAges 18 years+ - NCT06798116Enrolling by invitation
Gum disease treatment with platelet-rich fibrin and albumin gel
This study tests a new treatment for severe gum disease. It combines a natural blood product (platelet-rich fibrin) with a special albumin gel to help repair bone defects around teeth. The goal is to see if this mixture helps the bone grow back better than standard treatment.
Al MansurahAges 25–55 - NCT05384132Recruiting
Dental gel trial with deep cleaning for gum disease
This study tests whether a new dental gel used along with deep gum cleaning (scaling and root planing) can improve periodontitis. If you qualify, you would receive standard gum treatment plus the study gel, then be followed over time.
Birmingham, AlabamaAges 18–85 - NCT07746206RecruitingEarly Phase 1
Insulin vs hyaluronic acid gel for advanced gum disease
This study compares two treatments applied directly to the gums to see which one better helps severe gum disease (periodontitis) heal. If you have advanced gum disease and haven't had treatment recently, you may be able to join.
CairoAges Any age
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Common questions
- Are there clinical trials for periodontal pocket?
- Yes. Clin2 currently lists 25 recruiting periodontal pocket studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a periodontal pocket trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a periodontal pocket trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.