Clinical trials
Intrabony Periodontal Defect clinical trials
Below are recruiting intrabony periodontal defect clinical trials, each written for real people, not researchers. We’re tracking 19 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06048042RecruitingPhase 4
Comparing tooth graft vs bone graft for gum disease bone loss
This trial tests if using a tooth that is removed (like a wisdom tooth) to fill deep gum pockets works as well as using a piece of your own bone. It may help rebuild the bone around a damaged tooth.
CairoAges 18–50 - NCT05442034RecruitingPhase 1/Phase 2
Two gum treatments for deep bone defects in teeth
This study tests whether one of two treatments can improve healing of “intra-bony” gum/bone defects around teeth after deep cleaning. It may help some people with periodontal disease who have pockets deep enough to involve the bone but with certain health and dental conditions.
Davie, FloridaAges 18 years+ - NCT07613606Recruiting
Platelet-Rich Fibrin Injection for Gum Disease Treatment
This study tests a new injectable treatment using your own blood cells to help repair damaged gum tissue and bone around teeth affected by periodontal disease (gum disease). The goal is to see if this minimally invasive approach can regenerate healthy gum and bone without major surgery.
CairoAges 18 years+ - NCT06768424Recruiting
Treating deep gum pockets with laser or scalpel and platelet gel
This study compares two ways to fix deep gum pockets around teeth: a laser (MIST) or a traditional scalpel (GBT). Both methods use a gel made from your own blood (PRF) to help healing. The goal is to see which works better.
Budapest, BudapestAges 18–65 - NCT06347263Recruiting
Gum surgery technique for deep pockets between teeth
This trial tests a surgical technique to treat deep gum pockets between teeth. It compares using a special gum-saving method alone, with a bone graft, or with a platelet-rich fibrin injection to see which helps heal the bone best.
CairoAges 18–50 - NCT07683962Recruiting
Early healing and gum surgery outcomes
This trial tests whether early wound healing affects the results of regenerative gum surgery, which aims to rebuild bone around teeth affected by advanced gum disease.
Rome, RomeAges 18 years+ - NCT05858411Recruiting
Biologic gum treatments added to non-surgical cleaning
This trial studies whether adding a biologic medicine to standard non-surgical gum (periodontal) treatment can improve deep gum pockets in certain bone defects. It may help people whose gum disease has specific “intrabony” defects, but you must meet several health and medication rules.
TiranaAges 18 years+ - NCT06694168Recruiting
Gum surgery to repair bone loss, with or without your own healing proteins
This trial tests a gum surgery technique that preserves more of your gum tissue, with or without a special protein-rich material made from your own blood (L-PRF), to repair bone loss from gum disease.
Santiago, San BernardoAges 18 years+ - NCT07146776Recruiting
Injectable PRF and bone graft for gum disease bone defects
This trial tests a treatment for deep gum disease pockets using a combination of your own blood components (injectable platelet-rich fibrin) and a bone graft material. It aims to help regenerate bone lost to periodontitis.
Istanbul, ÜsküdarAges 18–65 - NCT07522684Recruiting
Gel treatment for deep gum bone loss around teeth
This trial tests a special gel made with growth-promoting compounds and animal-derived material to help repair deep bone loss in the gums around teeth. It may help restore bone that periodontitis (advanced gum disease) has damaged.
Ribeirão Preto, São PauloAges 18 years+ - NCT07546279Recruiting
Bone substitutes with gum graft for deep gum pockets
This trial tests two different bone-filling materials combined with a gum graft to repair deep pockets in your gums caused by gum disease. The goal is to help your gums heal and regain support around your teeth.
MilanAges Any age - NCT07671963Recruiting
Bone Graft Options for Gum Disease Surgery
This trial tests two bone-replacement materials (a synthetic bone substitute and a natural bone graft) placed during gum surgery to see which one better helps rebuild bone and gum support around teeth with deep pockets.
Cagliari, ItalyAges 18–80 - NCT06798116Enrolling by invitation
Gum disease treatment with platelet-rich fibrin and albumin gel
This study tests a new treatment for severe gum disease. It combines a natural blood product (platelet-rich fibrin) with a special albumin gel to help repair bone defects around teeth. The goal is to see if this mixture helps the bone grow back better than standard treatment.
Al MansurahAges 25–55 - NCT06633640Enrolling by invitationEarly Phase 1
Algae bone graft for gum disease bone defects
This study tests a new bone graft material made from algae, used with a collagen membrane, to help repair bone damage caused by gum disease. It might be an option if you have a deep pocket in the bone around a tooth and are healthy enough for the procedure.
CairoAges 20–65 - NCT03997578Recruiting
Gum surgery for deep periodontal bone defects
This trial studies a specific gum surgery technique plus a biologic product to help fill deep gum/bone defects from periodontitis (gum disease). It may help reduce gum pocket depth and improve healing around affected teeth.
MurciaAges 18 years+ - NCT07722390Recruiting
Injection treatment for deep gum pockets
This study tests whether injecting a special substance made from your own blood can help treat deep gum pockets without surgery. It may be an option for people with advanced gum disease who have already had initial cleaning.
CairoAges Any age - NCT04254861Recruiting
Platelet treatment for deep gum bone defects
This trial studies an “autologous platelet concentrate” (a gel made from your own blood) to help heal deep bone defects caused by periodontitis. It’s meant for adults with specific measurements in one or more gum pockets and bone areas after recent non-surgical gum treatment.
LondonAges 25–80 - NCT06309719Recruiting
Hyaluronic acid and polynucleotides for gum disease treatment
This trial tests if a gel made from hyaluronic acid and polynucleotides can help repair gum damage in people with advanced gum disease. You may be eligible if you have deep pockets between your teeth and gums that haven't healed after standard cleaning.
LondonAges 18 years+ - NCT07339605Recruiting
Gum bone regeneration with hyaluronic acid vs enamel matrix
This trial compares two treatments to help regrow bone and gum tissue around teeth with deep bone defects. It tests if hyaluronic acid works as well as enamel matrix derivative, both applied during a minimally invasive procedure.
Valencia, ValenciaAges 18 years+
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Common questions
- Are there clinical trials for intrabony periodontal defect?
- Yes. Clin2 currently lists 19 recruiting intrabony periodontal defect studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a intrabony periodontal defect trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a intrabony periodontal defect trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.