Clinical trials
Periodontal Bone Loss clinical trials
Below are recruiting periodontal bone loss clinical trials, each written for real people, not researchers. We’re tracking 41 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03997578Recruiting
Gum surgery for deep periodontal bone defects
This trial studies a specific gum surgery technique plus a biologic product to help fill deep gum/bone defects from periodontitis (gum disease). It may help reduce gum pocket depth and improve healing around affected teeth.
MurciaAges 18 years+ - NCT05533528Recruiting
Save gum tissue in surgery for severe periodontitis
This trial studies a way to preserve gum (periodontal) “granulation” tissue during surgical treatment for severe periodontitis (gum disease). It may help patients heal better after surgery, especially when deep gum pockets do not improve after non-surgical care.
MurciaAges 18 years+ - NCT07146776Recruiting
Injectable PRF and bone graft for gum disease bone defects
This trial tests a treatment for deep gum disease pockets using a combination of your own blood components (injectable platelet-rich fibrin) and a bone graft material. It aims to help regenerate bone lost to periodontitis.
Istanbul, ÜsküdarAges 18–65 - NCT07254117Recruiting
Study on gum tissue healing for severe gum disease
This trial tests whether special granulation tissue can help regenerate bone and gum support in people with severe gum disease who still have deep bone pockets after initial treatment. It may offer a better way to heal these defects.
RigaAges Any age - NCT07615361Enrolling by invitation
Tooth Graft and Laser Therapy for Dental Implants
This study tests whether material from extracted teeth, combined with low-level laser treatment, can help bone heal better before dental implants are placed. The goal is to improve implant success and reduce bone loss after tooth removal.
Istanbul, UskudarAges 18–65 - NCT07573761Enrolling by invitation
Tooth Grafts to Help Bone Grow for Dental Implants
This trial tests whether material made from extracted teeth can help bone regrow in the jaw after tooth removal, so you can get a dental implant. Researchers will compare this new approach to see if it works better for rebuilding bone in areas where teeth need to be replaced.
Istanbul, UskudarAges 18–65 - NCT06798116Enrolling by invitation
Gum disease treatment with platelet-rich fibrin and albumin gel
This study tests a new treatment for severe gum disease. It combines a natural blood product (platelet-rich fibrin) with a special albumin gel to help repair bone defects around teeth. The goal is to see if this mixture helps the bone grow back better than standard treatment.
Al MansurahAges 25–55 - NCT05932017Enrolling by invitation
Compare two ways to see during gum surgery
This trial compares two tools surgeons use to see during gum (periodontal) surgery: magnifying loupes versus a videoscope. It may help improve how the procedure is done for people with more severe gum disease.
Dallas, TexasAges 18 years+ - NCT06773923Enrolling by invitationPhase 3
3D-printed bone scaffold trial for dental implants
This trial tests a 3D-printed scaffold that dissolves over time to help regrow jawbone for dental implants. It is for people in Valdivia, Chile, who need bone buildup in the lower jaw.
ValdiviaAges 30–70 - NCT06309719Recruiting
Hyaluronic acid and polynucleotides for gum disease treatment
This trial tests if a gel made from hyaluronic acid and polynucleotides can help repair gum damage in people with advanced gum disease. You may be eligible if you have deep pockets between your teeth and gums that haven't healed after standard cleaning.
LondonAges 18 years+ - NCT07666126Recruiting
Uric acid and gum bone health study
This study looks at whether high uric acid levels affect the bone around your teeth. If you are between 18 and 65, have at least 20 natural teeth, and are either healthy or have high uric acid and gum disease, this trial may be for you.
RizeAges 18–65 - NCT07718932Recruiting
Healing gel for wisdom tooth extraction recovery
This trial tests a regenerative gel placed in the socket after wisdom tooth removal to improve healing. It may reduce pain, swelling, and speed up recovery.
ThessalonikiAges 18–35 - NCT07446127Recruiting
Adding Laser to Gum Disease Treatment
This trial tests adding a special laser (diode laser) to standard deep cleaning for gum disease. The goal is to see if the laser helps reduce infection and improve healing better than cleaning alone.
Afula, NorthAges 18 years+ - NCT06123000Recruiting
Comparing two surgeries for gum disease
This study compares two types of gum surgery for people with advanced gum disease. It's designed to see which method works better for treating deep gum pockets and saving bone.
Florence, FIAges 18 years+ - NCT06803576Enrolling by invitation
Long-term study of dental implants after 10 to 22 years
This study looks at how well dental implants work and how healthy the mouth stays more than 10 years after implant placement. The goal is to learn about implant success and any gum or bone changes over time.
ThessalonikiAges 18 years+ - NCT05240417Recruiting
Bone healing support after tooth extraction with a special shield
This study looks at whether a specific technique can help your jawbone stay in better shape after removing teeth in the upper and lower jaw. If you need certain front-to-back extractions, you may be offered this approach to improve healing and bone preservation.
MadridAges 18–80 - NCT07508033RecruitingPhase 1/Phase 2
Stem cell exosomes vs platelet-rich fibrin for socket healing
This trial tests whether stem cell exosomes (tiny healing particles from stem cells) work better than platelet-rich fibrin (a blood-derived clot) to help a tooth socket heal after extraction. It may help if you need a single front or premolar tooth removed and are generally healthy.
Tanta, Gharbia GovernorateAges 20–45 - NCT07638319RecruitingEarly Phase 1
Bone filler to preserve jawbone after tooth extraction
This early-stage trial tests a bone filler material (Neocement Inject P) placed in the socket after tooth removal to help preserve jawbone volume. This may help if you need a dental implant later.
Caparica, Monte Da CaparicaAges 18 years+ - NCT07339605Recruiting
Gum bone regeneration with hyaluronic acid vs enamel matrix
This trial compares two treatments to help regrow bone and gum tissue around teeth with deep bone defects. It tests if hyaluronic acid works as well as enamel matrix derivative, both applied during a minimally invasive procedure.
Valencia, ValenciaAges 18 years+ - NCT07419269Recruiting
Comparing donor vs. patient bone grafts for jawbone repair
This trial tests whether donated (allogenic) bone blocks work as well as your own bone to rebuild the jaw so dental implants can be placed. It's for people missing 1-4 teeth where the bone ridge is too thin.
Graz, StyriaAges 18 years+ - NCT07669792Recruiting
Bone shell vs fabric for narrow lower jawbone
This study compares two ways to rebuild a narrow lower jawbone so you can get dental implants. One method uses a special bone shell technique, and the other uses a strong fabric material. Your doctor will check if your jawbone is wide enough and healthy for this surgery.
CairoAges 18–65 - NCT06559605Recruiting
Comparing 3D Zirconia Barrier vs Titanium Mesh for Bone Growth
This study tests a new 3D-printed zirconia barrier to see if it helps grow bone better than a standard titanium mesh. It may be an option if you need more jawbone for dental implants.
CairoAges 20–70 - NCT07509281Recruiting
How implant parts affect healing and gum health
This trial compares different shapes and heights of the abutment (the connector piece between the implant and crown) to see how they affect gum and bone healing. It is for people who need a single or few back teeth replaced with a dental implant.
Valencia, ValenciaAges 18 years+ - NCT06533397Recruiting
Testing a new bone graft for sinus lifts
This study tests a new bone graft material for sinus lifts, a procedure to add bone in the upper jaw so dental implants can be placed. It may help people who are missing bone in the back of their upper jaw due to enlarged sinuses.
Budapest, BudapestAges 18 years+
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Common questions
- Are there clinical trials for periodontal bone loss?
- Yes. Clin2 currently lists 41 recruiting periodontal bone loss studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a periodontal bone loss trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a periodontal bone loss trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.