Clinical trials
Perioperative clinical trials
Below are recruiting perioperative clinical trials, each written for real people, not researchers. We’re tracking 332 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06092671Recruiting
Can FPCA prevent confusion in young kids after surgery?
This study tests whether a medicine called FPCA can prevent sudden confusion (delirium) in young children after surgery. If your child is having short surgery with mask anesthesia for the first time, this study may help them have a smoother recovery.
Wenzhou, ZhejiangAges 2–6 - NCT06012760Recruiting
Can iron and vitamin C reduce transfusions during heart surgery?
This trial is testing whether giving iron plus vitamin C before heart surgery can reduce the need for blood transfusions. It is for people with low iron and anemia who are scheduled for bypass or valve surgery.
Hangzhou, ZhejiangAges 18 years+ - NCT05679557Recruiting
Assessing frailty before bladder surgery to improve recovery
This trial tests whether a thorough “geriatric assessment” (a health check focused on older adults) can help you be better prepared for bladder removal surgery. It may guide supportive care before and around surgery to improve safety and recovery.
OdenseAges 65 years+ - NCT02573532Recruiting
Tracking heart damage after non-cardiac surgery
This study looks at whether patients experience heart muscle injury during or shortly after non-cardiac surgery. It aims to understand how common this is and what it means for recovery.
Basel, Canton of Basel-CityAges 45 years+ - NCT07843212Recruiting
Nerve block for breast cancer surgery
This study tests a nerve block (called SPSIP) given during breast cancer surgery to see if it reduces inflammation and affects a protein called TLR4, which may help with pain and recovery. If you're having breast cancer surgery, this might help you heal better with less discomfort.
Çorum, ÇorumAges 18–85 - NCT07414706RecruitingPhase 3
Numbing medicines for faster recovery after keyhole colorectal surgery
This study tests whether giving a numbing medicine (lidocaine) through an IV plus a local anesthetic at the surgery site can help you recover faster and with less pain after keyhole surgery for colorectal cancer.
AmiensAges 18 years+ - NCT07441421Recruiting
Improved pain relief for brain tumor surgery
This study tests a combination of pain-relief methods given before, during, and after brain surgery to see if they better control pain and help you recover with fewer side effects. It's for adults having surgery to remove a brain tumor.
BeijingAges 18–65 - NCT07672860RecruitingPhase 2
UDCA to protect kidneys during partial nephrectomy
This clinical trial is testing whether a medicine called ursodeoxycholic acid (UDCA) can help protect the kidneys during partial nephrectomy (removing only the tumor while keeping the healthy part of the kidney). It is for people with early-stage kidney tumors who will have temporary interruption of blood flow to the kidney during surgery.
Nanjing, JiangsuAges 18–75 - NCT03125980RecruitingPhase 3
Chemo timing before vs after colon cancer surgery
This Phase 3 study compares two schedules of a colon cancer chemo combination: starting before surgery or starting after surgery. It aims to see which timing helps people live longer and lowers cancer coming back.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT04973579Recruiting
Stent plus heart surgery for high risk carotid patients
This trial looks at whether doing carotid artery stenting at the same time as heart surgery is safe and effective for people at high risk of stroke around the time of surgery. It targets people with significant carotid narrowing who also need heart surgery for specific heart problems.
KrakowAges 18 years+ - NCT02800395Recruiting
Study links brain changes to diet and blood markers in Alzheimer’s
This study looks at how diet-related and blood “stress” markers relate to how thinking and memory decline over time in people with Alzheimer’s. It may help researchers find useful biomarkers to better track progression and guide future care.
Pierre-BéniteAges 55 years+ - NCT04908566RecruitingPhase 2
PD-1 immunotherapy plus chemotherapy before and after gastric surgery
This trial studies whether adding a PD-1 immune therapy to chemotherapy around the time of surgery can improve outcomes for people with locally advanced stomach or stomach–esophagus junction cancer. It aims to better control the cancer before and reduce the chance it comes back after surgery.
Tianjin, Tianjin MunicipalityAges 18–75 - NCT05182944RecruitingPhase 2
Perioperative immunotherapy plus chemotherapy for resectable throat cancer
This trial studies whether adding camrelizumab (an immune system drug) to chemotherapy before and around surgery can improve outcomes for people with resectable esophageal squamous cell carcinoma (ESCC). If you are eligible, treatment is given around the time of planned surgery to remove the tumor and lymph nodes.
Zhengzhou, HenanAges 18–80 - NCT04792554Recruiting
Study of aging around major non-heart surgery
This study looks at changes in health and function in older adults before and after major surgery. It may help doctors understand how “aging” affects recovery and what could improve outcomes.
SingaporeAges 65–100 - NCT04451473Recruiting
Compare recovery programs after lung surgery
This trial compares two ways of helping patients recover after lung surgery: a “enhanced recovery” plan versus standard care. It may help your team find a recovery approach that improves comfort and recovery after surgery for certain lung problems.
Jinan, ShandongAges 18–85 - NCT05755230Recruiting
Study of health results around surgery
This study follows people who are having surgery to see what happens before, during, and after the procedure. It may help doctors understand what factors are linked to better recovery.
Buenos AiresAges Any age - NCT04654923Recruiting
Survey of allergic reactions around anesthesia
This study collects information about people who had an allergic-type reaction around surgery or anesthesia. It aims to understand how often these reactions happen and to improve future care. You may be able to join if your reaction fits the time window and you agree to use your records.
StrasbourgAges 7 years+ - NCT05729646RecruitingPhase 2
Pre-surgery chemotherapy with toripalimab for dMMR stomach cancer
This trial studies whether adding toripalimab (an immune therapy) to chemotherapy before and around surgery can improve outcomes for people with certain mismatch repair–deficient stomach cancers. It mainly targets tumors that are dMMR and not HER2-positive.
Hangzhou, ZhejiangAges 18–80 - NCT05264896RecruitingPhase 3
Stomach cancer surgery plus two chemo plans
This trial compares two chemotherapy schedules around stomach cancer surgery: giving chemo before and after surgery (FLOT) versus giving chemo after surgery (XELOX). It’s meant to see which plan works better and is easier to tolerate for locally advanced disease that has not spread.
Hong KongAges 18 years+ - NCT06056336RecruitingPhase 2
Perioperative tislelizumab plus chemo for esophageal cancer
This trial tests whether giving tislelizumab (an immunotherapy) along with chemotherapy before and after surgery can help people with a type of esophageal cancer called squamous cell carcinoma. The goal is to see if this combination improves outcomes for patients whose cancer is in the chest and can be removed with surgery.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06155383RecruitingPhase 2
Surgery and immunotherapy combo for stomach cancer
This trial tests a combination of three drugs (Disitamab Vedotin, Toripalimab, and XELOX) given before and after surgery for gastric or gastroesophageal junction cancer. The goal is to see if this treatment helps shrink the tumor and prevent it from coming back.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05872685RecruitingPhase 2
Perioperative chemo plus serplulimab for specific stomach cancers
This Phase 2 trial tests whether adding serplulimab (an immune medicine) to standard chemotherapy before and/or around surgery can improve outcomes for people with certain locally advanced stomach cancer. You may get serplulimab or a placebo, and researchers will compare results to see if the immune add-on helps.
Hangzhou, ZhejiangAges 18–80 - NCT06163729RecruitingPhase 2
Testing camrelizumab plus chemo and radiation before/after surgery for stomach-esophagus cancer
This trial tests combining the immunotherapy drug camrelizumab with chemotherapy and radiation before and after surgery for a specific type of stomach-esophagus cancer. It aims to see if this approach helps shrink the tumor and improve outcomes.
Beijing, Beijing MunicipalityAges 18–80 - NCT07870577Recruiting
Nerve health during bladder cancer treatment
This study looks at nerve problems (peripheral neuropathy) in people with muscle-invasive bladder cancer who receive a combination of two drugs, enfortumab vedotin and pembrolizumab, before or after surgery. The goal is to understand how these treatments affect nerves and to help manage side effects.
Munich, BavariaAges 18 years+
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Common questions
- Are there clinical trials for perioperative?
- Yes. Clin2 currently lists 332 recruiting perioperative studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a perioperative trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a perioperative trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.