Clinical trials
Perioperative clinical trials
Below are recruiting perioperative clinical trials, each written for real people, not researchers. We’re tracking 336 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05971810Recruiting
Oral cleaning and nutrition support around surgery for older adults
This trial studies whether cleaning the mouth before and after major surgery, plus special nutrition support, can lower the risk of breathing complications in older adults. It may help patients who are at higher risk for lung problems around the time of general anesthesia.
Shijiazhuang, HebeiAges 65 years+ - NCT05714007RecruitingPhase 4
Iron infusion for anemia after spinal deformity surgery
This trial looks at whether a specific iron infusion (ferric derisomaltose) can help treat anemia after spinal deformity surgery. You may be eligible if your blood counts show anemia soon after surgery and it’s likely due to iron deficiency.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05774717RecruitingPhase 1
Tranexamic acid for bleeding after open nose surgery
This Phase 1 study tests whether tranexamic acid (a medicine that helps reduce bleeding) can lessen bleeding, swelling, and bruising after open rhinoplasty. You may be asked to take it around the time of surgery if you meet safety and lab criteria.
Nashville, TennesseeAges 18 years+ - NCT05715931RecruitingPhase 2
Surgery chemotherapy plus anti-HER2 and anti–immune therapy for HER2 stomach cancer
This Phase 2 trial tests adding chemotherapy plus trastuzumab and toripalimab around the time of surgery for HER2-positive, locally advanced stomach or esophagus-stomach junction cancer. It aims to shrink the cancer and reduce the chance it comes back by attacking it through more than one pathway.
Hangzhou, ZhejiangAges 18–80 - NCT05460689Recruiting
Phone app support for families before pediatric ear-nose-throat surgery
This trial tests whether a mobile phone app can better support caregivers of children going into tonsil and/or adenoid surgery (sometimes with ear tube placement) around the time of the operation. It may help families feel more informed and prepared before and after surgery.
TriesteAges 2–10 - NCT05380531Recruiting
Personalized pain plan for planned C-section using opioid options
This trial tests a personalized approach to pain control during and after a scheduled C-section. It may help by matching pain medicine choices to each person’s needs, including the use of in-hospital opioids for relief.
Indianapolis, IndianaAges 18 years+ - NCT05257746Recruiting
Testing bladder and rectal function after rectal surgery
This study follows people after rectal surgery to check how well the rectum and urinary (bladder) functions work over time. It may help doctors better understand recovery and what can improve quality of life after surgery.
Dresden, SaxonyAges 18 years+ - NCT03954678Recruiting
Exercise program during hospital care for urologic surgery
This study looks at whether doing an exercise routine around the time of urologic (urinary tract) surgery is safe and helpful for recovery. It asks you to do daily steps, answer questionnaires, and allow routine bloodwork.
Atlanta, GeorgiaAges 18 years+ - NCT04331249Recruiting
Monitoring heart device during and around your procedure
This trial looks at how to manage and check implanted heart devices (pacemakers/defibrillators) during and around a planned procedure. It may help teams improve safety and decision-making during surgery or catheter procedures.
Fürth, BavariaAges 18 years+ - NCT04266574Recruiting
Blood pressure–guided care for older or frail surgical patients
This study tests a goal-based blood pressure treatment approach during major surgery for people at higher risk (often older or frail with high blood pressure). The goal is to see if this BRAIN-targeted strategy can improve how patients do after surgery.
Rozzano, MilanAges 18 years+ - NCT06812039RecruitingPhase 2
Perioperative treatment for high-risk liver cancer using HAIC, donafenib, and sintilimab
This trial tests a combination of treatments—chemotherapy delivered through the liver artery (HAIC), a targeted drug (donafenib), and an immunotherapy (sintilimab)—given before and after surgery for liver cancer that has a high chance of coming back. The goal is to see if this approach can lower the risk of recurrence.
Fuzhou, FujianAges 18–75 - NCT06387810RecruitingPhase 2
Chemo before and after surgery for borderline resectable pancreatic cancer
This trial tests a combination of chemotherapy drugs (irinotecan liposome, 5-FU, leucovorin, and oxaliplatin) given before and after surgery for people with pancreatic cancer that is on the border of being removable. The goal is to see if this treatment helps shrink the tumor and improve outcomes.
Beijing, Beijing MunicipalityAges 18–110 - NCT06425406Recruiting
Preventing low oxygen in children during anesthesia with HFNC
This trial tests whether a special oxygen device (HFNC) can prevent low oxygen levels in children during anesthesia. It is for children aged 2-10 who are generally healthy and having surgery.
Zhengzhou, HenanAges 2–10 - NCT07629323Enrolling by invitation
Spinal Pain Relief During Hiatal Hernia Surgery
This trial tests whether injecting pain medication directly into the spinal fluid during a minimally invasive stomach surgery (called fundoplication) helps reduce pain after the operation. Fundoplication is used to treat severe acid reflux.
Karlstad, Värmland CountyAges 18 years+ - NCT06816914RecruitingPhase 2
Perioperative chemo for resectable pancreatic cancer
This trial tests a combination of chemotherapy drugs (liposomal irinotecan with fluorouracil, leucovorin, and oxaliplatin) given before and after surgery for pancreatic cancer that can be fully removed. It aims to see if this approach improves outcomes for patients with stage I or II disease.
Kaohsiung CityAges 20–75 - NCT06743464Recruiting
Rifaximin before liver transplant for better early liver function
This trial tests whether taking the antibiotic rifaximin just before and after a living-donor liver transplant can help prevent early problems with the new liver. It may be an option for adults having this surgery at the study hospital.
New Delhi, National Capital Territory of DelhiAges 18 years+ - NCT05812248Recruiting
Tracking heart and blood vessel events after major non-heart surgery
This study follows people after major surgery to see what predicts heart and blood vessel problems later. It does not test a new drug; it mainly collects health information to help clinicians reduce risk.
Guangzhou, GuangdongAges 45 years+ - NCT07454720RecruitingPhase 2/Phase 3
Study of Adebrelimab with SHR-8068 and chemoradiation before surgery for rectal cancer
This trial tests whether adding two immunotherapy drugs (adebrelimab and SHR-8068) to standard chemoradiation before surgery can improve outcomes for adults with locally advanced rectal cancer that can be surgically removed.
Wuhan, HubeiAges 18–75 - NCT07531615Recruiting
Abdominal Pressure Monitoring During Hernia Repair Surgery
This study measures abdominal pressure before, during, and after hernia repair surgery to understand how the body responds to treating hernias. It may help doctors improve surgical techniques and patient recovery.
Nice, Alpes-MaritimesAges 18 years+ - NCT07192575Recruiting
Preventing lung problems after laparoscopic liver surgery
This trial tests if special breathing exercises before surgery can help prevent lung complications after laparoscopic (keyhole) liver surgery. It may benefit you by reducing your risk of pneumonia or other breathing issues after the procedure.
KuopioAges 18 years+ - NCT07522151RecruitingPhase 3
Adebrelimab with Surgery for Stomach Cancer
This trial tests a new immunotherapy drug called adebrelimab combined with chemotherapy and surgery for stomach cancer or junction cancers (where the stomach meets the esophagus). The goal is to see if this treatment helps prevent cancer from coming back after surgery.
Beijing, Beijing MunicipalityAges 18–75 - NCT06059976Recruiting
Hypnosis during heart surgery recovery study
This study looks at the use of hypnosis during heart surgery to see how it affects recovery. If you are having major heart surgery and have already had hypnosis sessions before, during, or after the operation, you may be eligible to participate.
GrenobleAges 18 years+ - NCT07573969RecruitingPhase 3
Pain Relief Medicines Added to Spinal Injection for Back Surgery
This trial tests whether adding one of two different medicines (dexmedetomidine or ketamine) to a numbing injection in the lower spine improves pain relief after back surgery. You would receive the injection while asleep during surgery to help manage pain afterward.
CairoAges 21–60 - NCT07537491Recruiting
AI tool to predict surgery outcomes in colorectal cancer
This study uses artificial intelligence to analyze tissue samples from your colorectal cancer surgery to help predict how you'll recover and what your long-term outlook might be. Researchers will examine your tumor tissue under a microscope to build a computer model that could help doctors personalize your care plan.
Brandenburg an der HavelAges 18 years+
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Common questions
- Are there clinical trials for perioperative?
- Yes. Clin2 currently lists 336 recruiting perioperative studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a perioperative trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a perioperative trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.