Clinical trials
Perioperative clinical trials
Below are recruiting perioperative clinical trials, each written for real people, not researchers. We’re tracking 336 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06765772Recruiting
Nerve blocks for pain relief during tummy tuck surgery
This trial compares two types of nerve blocks (with numbing medicine) to reduce pain during and after tummy tuck surgery. The goal is to see if combining two blocks works better than one block alone.
Cairo, Cairo GovernorateAges 21–60 - NCT06989229Recruiting
Nutritional care before and after joint replacement surgery
This trial tests if special nutritional support before and after hip or knee replacement helps you recover faster. It is for people having planned (not emergency) surgery.
Brno, CzechiaAges 18 years+ - NCT07683377Recruiting
Stent-assisted coil treatment for ruptured brain aneurysms
This trial tests if using a stent with coils to treat a ruptured brain aneurysm is safe and effective. It is for people who have a specific type of aneurysm (wide-necked, cystic) and are treated soon after the rupture.
Xi'an, ShaanxiAges 18–80 - NCT07519733Recruiting
Exercise Testing Before High-Risk Surgery
This study tests whether a simple exercise test before surgery can help doctors better predict and prevent complications in older adults undergoing major operations. You'll do a gentle exercise test on a stationary bike or treadmill to measure your fitness level.
New Haven, ConnecticutAges 45 years+ - NCT07510347Recruiting
Pain relief study for sleeve gastrectomy patients
This study tests if giving pain medicine in a different area of the abdomen can reduce pain after weight-loss surgery. It may help you feel more comfortable after your sleeve gastrectomy.
Shibīn al Kawm, MenofiaAges 20–60 - NCT06482788RecruitingPhase 2
Immunotherapy plus chemo before & after junction cancer surgery
This trial tests giving an immunotherapy drug (adebrelimab) along with two chemotherapy drugs (capecitabine and oxaliplatin) before and after surgery for a specific type of stomach-cancer junction tumor. It aims to see if this combination is safe and effective in shrinking the tumor and improving outcomes.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07483567RecruitingPhase 2
Combination treatment before and after stomach cancer surgery
This trial tests a combination of experimental drugs (IBI343, Sintilimab, and chemotherapy) before and after surgery for a specific type of stomach cancer that is CLDN18.2 positive. The goal is to see if this treatment shrinks the tumor and helps prevent the cancer from coming back.
Beijing, Beijing MunicipalityAges 18–75 - NCT07127042RecruitingPhase 2
Testing a drug to reduce bleeding during knee replacement
This trial tests an experimental drug called BT-114143 to see if it reduces bleeding during and after total knee replacement surgery. It may be a good option for people with osteoarthritis who are having their first knee replacement.
Chengdu, Si'ChuanAges 18–70 - NCT07396636Recruiting
Using machine learning to manage low blood pressure during surgery
This study tests whether an AI tool can help doctors better manage low blood pressure during planned surgeries. If you are having an elective surgery with general anesthesia and need an arterial line for monitoring, this trial may be for you.
Konya, Konya/MeramAges 18 years+ - NCT05872685RecruitingPhase 2
Perioperative chemo plus serplulimab for specific stomach cancers
This Phase 2 trial tests whether adding serplulimab (an immune medicine) to standard chemotherapy before and/or around surgery can improve outcomes for people with certain locally advanced stomach cancer. You may get serplulimab or a placebo, and researchers will compare results to see if the immune add-on helps.
Hangzhou, ZhejiangAges 18–80 - NCT04908566RecruitingPhase 2
PD-1 immunotherapy plus chemotherapy before and after gastric surgery
This trial studies whether adding a PD-1 immune therapy to chemotherapy around the time of surgery can improve outcomes for people with locally advanced stomach or stomach–esophagus junction cancer. It aims to better control the cancer before and reduce the chance it comes back after surgery.
Tianjin, Tianjin MunicipalityAges 18–75 - NCT06603350Recruiting
How surgery factors affect recovery after lung transplant
This study looks at how things before, during, and right after lung transplant surgery affect recovery. Researchers want to learn what helps patients heal better so they can improve care.
Hangzhou, ZhejiangAges 18 years+ - NCT06864624RecruitingPhase 2
Perioperative sunvozertinib for stage II-IIIB NSCLC with EGFR exon 20 insertion
This trial tests the drug sunvozertinib before and after surgery for non-small cell lung cancer that has a specific EGFR mutation (exon 20 insertion). It aims to see if the drug can help shrink tumors and improve outcomes for patients whose cancer is at stage II, IIIA, or IIIB.
Changsha, HunanAges 18 years+ - NCT07293299Recruiting
PneumoRator monitoring study for planned surgery
This study tests a new device, the PneumoRator, which monitors your breathing and oxygen during surgery. It may help doctors track your recovery after major surgery.
SouthamptonAges 18 years+ - NCT06510010RecruitingPhase 2
Chemo plus H. pylori treatment for advanced stomach cancer
This trial tests whether adding H. pylori bacteria treatment to standard chemotherapy (before and after surgery) can improve outcomes for people with locally advanced stomach cancer. It combines oxaliplatin and S-1 chemo with antibiotics to clear the infection.
GuangzhouAges 18–75 - NCT05729646RecruitingPhase 2
Pre-surgery chemotherapy with toripalimab for dMMR stomach cancer
This trial studies whether adding toripalimab (an immune therapy) to chemotherapy before and around surgery can improve outcomes for people with certain mismatch repair–deficient stomach cancers. It mainly targets tumors that are dMMR and not HER2-positive.
Hangzhou, ZhejiangAges 18–80 - NCT07289321Enrolling by invitation
Pain relief study for robotic prostate surgery
This trial tests if adding tramadol and magnesium to a local anesthetic (ropivacaine) improves pain control after robotic prostate removal. It may help reduce the need for strong painkillers after surgery.
Athens, AtticaAges 40–80 - NCT06506292RecruitingPhase 2
Study of adebrelimab plus chemo before and after stomach cancer surgery
This trial tests combining adebrelimab (an immunotherapy) with chemotherapy (XELOX) before and after surgery for stomach cancer that hasn't spread. The goal is to see if this approach helps shrink tumors and improves outcomes.
Tianjin, Tianjin MunicipalityAges 18–75 - NCT07175779Recruiting
Comparing video calls vs. in-person visits for kids' surgery checkups
This trial tests whether a video call before surgery works as well as an in-person hospital visit for checking breathing risks in children getting their tonsils or adenoids removed. It may help families avoid extra trips to the hospital.
Bellinzona, Canton TicinoAges Up to 16 years - NCT07276126Recruiting
Enhanced recovery after cesarean and parent-infant bonding
This study tests if a special care plan called ERAS (Enhanced Recovery After Surgery) helps new mothers and fathers bond better with their babies after a planned or medically needed cesarean birth. You will be randomly assigned to standard care or the ERAS protocol to see which leads to stronger early bonding.
IstanbulAges 18–60 - NCT07179029Recruiting
Can anesthesia affect the heart during non-cardiac surgery?
This study looks at whether anesthesia can cause heart damage during non-cardiac surgeries. If you have certain health risks, participating may help doctors learn how to better protect your heart.
TübingenAges 40–80 - NCT07265973Recruiting
Preparing for recovery after vaginal prolapse surgery
This study tests a program of exercises and education before surgery to see if it helps people recover better after vaginal prolapse repair. It is for people scheduled for specific types of prolapse surgery.
Albuquerque, New MexicoAges 18 years+ - NCT05529940RecruitingPhase 3
FOLFIRINOX around surgery for resectable pancreatic cancer
This trial compares giving chemotherapy with FOLFIRINOX before and after surgery versus giving it mainly after surgery for people with resectable pancreatic duct cancer. It aims to improve outcomes by timing the treatment around the operation.
SeoulAges 19–80 - NCT07223853Recruiting
AI tool to help plan blood transfusions before surgery
This trial tests an AI decision-support tool that helps doctors decide if you might need a blood transfusion during surgery. The goal is to make safer and more personalized blood ordering decisions.
St Louis, MissouriAges 18 years+
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Common questions
- Are there clinical trials for perioperative?
- Yes. Clin2 currently lists 336 recruiting perioperative studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a perioperative trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a perioperative trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.