Clinical trials
Peripheral Neuropathy With Type 2 Diabetes clinical trials
Below are recruiting peripheral neuropathy with type 2 diabetes clinical trials, each written for real people, not researchers. We’re tracking 71 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07210203Recruiting
Nerve gliding for pain, balance, and quality of life in diabetic nerve damage
This study tests whether adding nerve gliding exercises (neural mobilization) to usual care can reduce pain, improve balance, and enhance quality of life for people with diabetic peripheral neuropathy. It may help if you have mild to moderate nerve pain and are between 50 and 75 years old.
IslamabadAges 50–75 - NCT06627322Recruiting
Diabetes type 2 trial for people with heart risks
This study compares different diabetes medicines to see which works best for people with type 2 diabetes who also have heart or blood vessel risks. It aims to find better treatment to protect your heart and kidneys.
DaeguAges 19 years+ - NCT07186660RecruitingPhase 2
Studying a new insulin sensitizer for type 1 diabetes
This trial tests an oral medication that may help your body respond better to insulin. It's for people with type 1 diabetes who use an automated insulin pump and are willing to take a daily pill for 12 weeks.
Charlottesville, VirginiaAges 18–45 - NCT07183761RecruitingPhase 2
Stem cell therapy for diabetic nerve pain
This study tests whether umbilical cord stem cells can help people with diabetic nerve damage in their legs who haven't gotten enough relief from standard treatments. It aims to improve symptoms like numbness, pain, and tingling.
Chongqing, Chongqing MunicipalityAges 18–80 - NCT07131410Enrolling by invitation
Hyaluronic acid cream to prevent foot ulcers in diabetes
This trial tests a cream made with hyaluronic acid, a natural substance that helps keep skin moist, to see if it can prevent foot sores in people with type 2 diabetes and nerve damage in their feet. If you have diabetes-related nerve issues and want to protect your feet, this study may be for you.
MálagaAges 18 years+ - NCT07078565Recruiting
Tai Chi vs. Otago Exercises for Diabetic Nerve Pain
This study compares gentle Tai Chi exercises with a modified Otago exercise program to see which better helps with pain, balance, and movement in people with diabetic nerve pain. If you have had type 2 diabetes for at least 5 years and have chronic nerve pain, this trial may help you find relief and improve your mobility.
Lahore, Punjab ProvinceAges 40–80 - NCT07036796RecruitingPhase 2
Melatonin for diabetic nerve pain
This trial tests whether melatonin can help relieve pain and discomfort from diabetic peripheral neuropathy (nerve damage caused by diabetes). If you have type 2 diabetes with nerve pain and are on stable diabetes medications, you may be eligible.
CairoAges 40–75 - NCT01793168Recruiting
Rare disease registry and history study
This study keeps a registry (a structured list) of people with rare diseases and may also track how the condition changes over time. It can help researchers better understand rare illnesses and find gaps in care, which may improve future treatments.
Sioux Falls, South DakotaAges Any age - NCT07028528RecruitingPhase 2
Study of Levagen+ for diabetic nerve pain
This trial tests if Levagen+ (a supplement) can reduce nerve pain caused by diabetes. It is for people with type 1 or type 2 diabetes who have significant nerve pain in their feet or legs.
Fortitude Valley, QueenslandAges 18–75 - NCT06959277Recruiting
Walkasins study for balance with peripheral neuropathy
This trial tests if a wearable device called Walkasins can improve balance and walking in people with peripheral neuropathy. It may help if you have trouble with balance and your foot size fits the device.
Mesa, ArizonaAges 55 years+ - NCT06861062Recruiting
Vitamin D and yeast beta-glucan for type 2 diabetes
This trial tests if taking vitamin D3 and yeast beta-glucan supplements can help control blood sugar and lower heart disease risk in people with type 2 diabetes. It may be an option for those who want to see if supplements can improve their diabetes management.
Nanning, GuangxiAges 40–79 - NCT06778005Recruiting
Ultrasound of leg nerves in type 2 diabetes with nerve damage
This study uses ultrasound (an imaging test) to measure the nerves in the legs of people with type 2 diabetes who have nerve damage. It helps doctors learn more about how diabetes affects nerves.
Istanbul, ÜsküdarAges 18–65 - NCT06734546Recruiting
Exercise and brain health in type 2 diabetes
This study tests whether regular exercise can improve brain health in people with type 2 diabetes. If you have type 2 diabetes, are not on insulin, are inactive, and are between 30 and 75 years old, you may be able to join.
Hasselt, LimburgAges 30–75 - NCT06619860RecruitingPhase 2
VX-993 for diabetic nerve pain
This trial tests a new medicine called VX-993 for people with diabetes who have had nerve pain in both feet or legs for at least a year. The goal is to see if it reduces pain and is safe.
Cullman, AlabamaAges 18–80 - NCT06628908RecruitingPhase 3
Study of suzetrigine for painful diabetic nerve damage
This trial tests an experimental medicine called suzetrigine to see if it can safely reduce pain caused by nerve damage from diabetes (diabetic peripheral neuropathy). It might be an option if you have had daily pain in both legs and current treatments haven't worked well enough.
Anniston, AlabamaAges 18–80 - NCT06480786Recruiting
Spinal cord stimulator for diabetic nerve and artery pain
This study tests if a spinal cord stimulator (a device that sends mild electrical pulses to the spine) can relieve severe leg pain caused by diabetic nerve damage and poor blood flow. It may help people who have not found enough relief from other treatments.
Omaha, NebraskaAges 19–89 - NCT06124586Recruiting
Early angioplasty for diabetic foot ulcers
This trial tests if an early procedure to open blocked leg arteries (angioplasty) helps heal foot ulcers in people with type 2 diabetes. It aims to improve blood flow and prevent amputation.
DüsseldorfAges 18 years+ - NCT05577390Recruiting
Comparing two treatments for diabetic nerve pain
This study compares two approaches to treating nerve pain caused by diabetes. You may be eligible if your diabetic neuropathy is moderate to severe and you can reliably use a phone for study steps.
Loma Linda, CaliforniaAges 45–85 - NCT05950659Recruiting
Wearable insoles to prevent repeat diabetic foot ulcers
This trial tests special sensory insoles (called Orpyx Sensory Insoles) to help prevent diabetic foot ulcers from coming back. It aims to reduce high-pressure foot spots for people who already had a healed nerve-related ulcer.
Baltimore, MarylandAges 18 years+ - NCT05633810RecruitingPhase 3
Testing colchicine plus coated aspirin to prevent heart events
This Phase 3 study tests whether colchicine and a special type of aspirin can lower the risk of future heart attacks, strokes, or other major heart problems in people with type 2 diabetes who have not had a prior heart event. It aims to reduce cardiovascular risk using medicines that may calm inflammation and protect blood vessels.
Bentley, Western AustraliaAges 55–80 - NCT04791371Recruiting
Study how fitness and insulin resistance relate to diabetes
This study looks at how low physical activity, insulin resistance in small blood vessels, and cardiorespiratory fitness connect to diabetes and blood sugar control. You may be eligible if you are generally sedentary and fit within the weight range, and if you do not have certain heart, lung, nerve, or medication factors.
Aurora, ColoradoAges 30–55 - NCT04442451Recruiting
Study how fatigue happens in prediabetes and type 2 diabetes
This study looks at why people with prediabetes or type 2 diabetes may feel unusually tired during activities. You may be asked to do exercise testing and answer questions to help researchers understand the body changes behind fatigue.
Ann Arbor, MichiganAges 30–85 - NCT07859111RecruitingPhase 3
YJ001 spray for diabetic nerve pain in the feet
This trial tests a spray called YJ001 for pain in the feet caused by diabetic nerve damage. It aims to see if the spray can reduce pain better than a placebo, and may offer a new way to manage this type of pain.
Beijing, Haidian DistrictAges 18 years+ - NCT07468474Recruiting
Finding Type 1 Diabetes Risk and Offering Education
This study is designed to help identify and monitor people at high risk for type 1 diabetes. It involves education and regular check-ups to better understand and manage the condition.
Beijing, Beijing MunicipalityAges 4 years+
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Common questions
- Are there clinical trials for peripheral neuropathy with type 2 diabetes?
- Yes. Clin2 currently lists 71 recruiting peripheral neuropathy with type 2 diabetes studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a peripheral neuropathy with type 2 diabetes trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a peripheral neuropathy with type 2 diabetes trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.