PET clinical trials

Electric fields with targeted radiation vs. alone for recurrent brain cancer

This trial tests whether adding a precise, MRI-guided radiation treatment to tumor-treating electric fields (TTFields) can help people with recurrent glioblastoma. You may qualify if your tumor has come back 1 to 3 times after standard therapy and you haven't had certain prior treatments.

Pet fish care for better diabetes management in teens

This study tests if taking care of a pet fish can help kids aged 10-13 with type 1 diabetes improve their blood sugar control and take more responsibility for their diabetes care.

Total-body PET scan using FDA-approved tracers for prostate or NET cancer

This pilot study tests a total-body PET scan with approved tracer medicines to help detect cancer spread in people with suspected metastatic prostate cancer or certain neuroendocrine tumors (NETs). You may be able to join if recent scans already suggest metastasis and you can safely complete the scan timing and positioning.

Brain scan study for aging adults in Baltimore

This study uses a special brain scan (amyloid PET) to look at brain changes in healthy older adults. It may help researchers learn more about aging and memory loss.

Understanding New Cachexia Subtypes Through Observational Epidemiological Research

PET scan study for Alzheimer's or mild cognitive impairment

This study uses a special PET scan to look at a brain protein called PDE4 in people with Alzheimer's disease or mild cognitive impairment. It may help researchers understand how this protein is involved in memory and thinking problems.

PET scan to study energy use in brain of people with cocaine use disorder

This study uses a special PET scan to look at how brain cells make energy, which may be changed by cocaine. It might help researchers find better ways to treat cocaine use disorder.

Clinical Applications of FAPI PET in Solid Tumors

ctDNA-Guided Therapy for Relapsed Hodgkin Lymphoma

This trial uses a blood test (ctDNA) to guide treatment for Hodgkin lymphoma that has come back or not responded to one prior treatment. You would receive a combination of drugs (pembrolizumab, gemcitabine, vinorelbine, and liposomal doxorubicin) to see if it works better.

Surgery-recovered prostate cancer treated with PET-guided radiation

This trial tests whether adding targeted radiation guided by a PET scan (along with hormone therapy) can improve outcomes for prostate cancer that has come back after surgery. The PET scan helps doctors look for spots outside the usual radiation area so treatment can be tailored.

Pet scan study of brain chemical norepinephrine

This study uses a special PET scan to look at the brain chemical norepinephrine, which may be linked to mood and anxiety. It helps researchers understand how the brain works by taking detailed pictures.

PET scan tracer to find lung or pancreas radiation injury

This Phase 2 study tests a special PET scan tracer to help doctors spot tissue damage after radiation treatment in people with certain lung or pancreatic cancers. The goal is to improve detection and planning around chemoradiation and surgery.

Brain PET scan for inflammation in fatty liver disease

This study uses a special PET scan to look for inflammation in the brain related to fatty liver disease. It may help researchers understand how liver health affects brain function.

Study of Pelabresib and Ruxolitinib for Myelofibrosis

This trial tests a combination of two drugs (pelabresib and ruxolitinib) for people with myelofibrosis whose spleen is enlarged and who have bothersome symptoms. It aims to see if adding pelabresib to standard care helps control the disease better.

PET scan for detecting heart amyloidosis

This study tests a new PET imaging agent that may help doctors see amyloid buildup in the heart more clearly. It may help people with heart amyloidosis or those suspected of having it.

MRI plus cognitive testing during glioma chemoradiation

This study uses MRI scans and related brain/cognitive testing while you receive standard chemotherapy and radiation for a high-grade brain tumor. It aims to see how MRI measures and brain testing may relate to your treatment response or brain function.

PET/MRI monitoring for PD-L1–positive triple-negative breast cancer

This early-phase study uses advanced PET/MRI scans to monitor how immunotherapy treatment works in people with triple-negative breast cancer that is PD-L1 positive. It may help doctors better track tumor changes in the body over time.

Brain scan to detect Alzheimer's plaques

This study tests a new PET brain scan that uses a special dye to show amyloid plaques, which are linked to Alzheimer's disease. It may help doctors see if your memory problems are caused by Alzheimer's or something else.

Study of heart effects of radiation therapy using PET-CT for stage III lung cancer

This study looks at whether PET-CT scans can help detect heart damage caused by radiation therapy in patients with stage III lung cancer. If you're getting chemotherapy and radiation together, you may participate to help doctors find ways to reduce heart risks.

PET Scan to Track Lung Cancer Treatment Response

This study uses a special PET imaging scan to help doctors see how well pembrolizumab (an immunotherapy drug) is working against advanced non-small cell lung cancer. You'll receive the scan along with your regular pembrolizumab treatment and possible radiation therapy to help measure treatment response.

PET imaging study for multiple solid tumors

This trial uses a special PET scan to take pictures of certain solid tumors. The scan uses a new dye that may help doctors see the tumors more clearly. You may be eligible if you have one of the listed cancers and are between 18 and 75 years old with good daily function.

Brain scan study for Alzheimer's research

This study uses brain scans (PET) to look at changes in the brain that may be related to memory problems or Alzheimer's disease. It aims to improve understanding of the disease and may help develop better treatments.

SLR-108 PET imaging study for metastatic solid tumors

This trial uses a special imaging agent called SLR-108 to take detailed PET scans of your cancer. It aims to see if this scan can help doctors better understand metastatic solid tumors that have grown after previous treatment.

Understanding how our brain experiences time

This study uses brain scans and simple tasks to explore how young and older adults perceive time. It aims to uncover the mental and brain processes behind our sense of time.