Clinical trials
Pharmacogenetics clinical trials
Below are recruiting pharmacogenetics clinical trials, each written for real people, not researchers. We’re tracking 30 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06335043Recruiting
Personalized medication matching for veterans with OSI
This trial tests whether using genetic information to guide medication choices can improve treatment for veterans with operational stress injuries (OSI). It aims to help find the right medication faster and with fewer side effects.
London, OntarioAges 18 years+ - NCT07810816Recruiting
Genetic testing for personalized pain relief after surgery
This study looks at how your genes affect your body's response to tramadol, a painkiller given through a pump after surgery. The goal is to see if your genetic makeup influences pain relief and side effects, which could help personalize pain treatment in the future.
Medellín, AntioquiaAges 18 years+ - NCT04507555Recruiting
Pharmacist-guided genetic testing to choose antidepressants
This study tests whether doing genetic testing before starting or adjusting antidepressants—guided by a pharmacist—can improve treatment for people with moderate to severe depression. The goal is to help match you with antidepressants more safely and effectively.
Münchenbuchsee, Canton of BernAges 18 years+ - NCT07060300Enrolling by invitation
Genetic testing for drug reactions in complex care children
This study looks at how children with complex medical conditions respond to medicines based on their genes. It may help personalize care by testing how your child's body processes certain drugs, all from a simple cheek swab.
Cincinnati, OhioAges Any age - NCT06929533Recruiting
Genetic testing to guide mental health medication
This study tests if using genetic information can help doctors choose the right mental health medication or dose. It may help find treatments that work better with fewer side effects.
Winnipeg, ManitobaAges 18 years+ - NCT06853587Recruiting
Genetic test to help pick antidepressant for teens
This study tests whether using a cheek swab DNA test can help choose a better antidepressant for teenagers with anxiety or depression. The goal is to see if this personalized approach leads to fewer side effects and better results.
Calgary, AlbertaAges 12–17 - NCT04623099RecruitingPhase 4
Personalized escitalopram dosing for anxious teens
This study tests whether a genetics-guided approach to choosing and adjusting escitalopram (an anxiety medicine) can improve safety and effectiveness for anxious teens. It also checks that participants have certain anxiety severity scores and can safely take the study medication.
Cincinnati, OhioAges 12–17 - NCT07582887Recruiting
Genetic Testing to Predict Side Effects from Breast Cancer Antibody Drugs
This study examines how genetic differences affect how your body handles three newer breast cancer medications (Sacituzumab Govitecan, Trastuzumab Deruxtecan, or Datopotamab Deruxtecan). A blood test will check your UGT1A1 gene to help doctors predict which side effects you might experience and adjust your treatment accordingly.
Granada, GranadaAges 18 years+ - NCT07455955RecruitingPhase 2
Custom anti-nausea treatment based on your genes
This trial tests if giving anti-nausea drugs based on your genetic makeup can better prevent vomiting and nausea from chemotherapy for early breast cancer. You will receive a personalized regimen tailored to your pharmacogenetic profile.
Hong KongAges 18–74 - NCT07422090Recruiting
Preventing suicide with digital and genetic tools
This trial uses smartphone data and genetic testing to help prevent future suicide attempts. It aims to find personalized ways to support people who have already had a suicide attempt.
Madrid, MadridAges 12 years+ - NCT07388407Recruiting
Genetics of leflunomide for rheumatoid arthritis
This study looks at how your genes might affect how well leflunomide works for rheumatoid arthritis. It is for Pakistani adults who are starting or recently started leflunomide, and will help doctors understand who might respond best.
Islamabad, Punjab ProvinceAges 20–65 - NCT07373470Recruiting
Pharmacist help with depression meds using your DNA
This trial tests whether a pharmacist can use your genetic information to better manage your depression medications. It may help find the right drug or dose for you.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT04964310Recruiting
Testing genetic risk for acetaminophen-related liver injury
This study looks at whether certain genes can predict who is more likely to get liver injury after taking acetaminophen (also found in some cold/flu medicines). By comparing people who were affected with people who were not, it may help doctors identify higher-risk patients in the future.
Nanjing, JiangsuAges 14 years+ - NCT07167329RecruitingPhase 2
Belzutifan for VHL syndrome: a real-world study
This trial tests the drug belzutifan (a pill taken by mouth) in people with VHL syndrome who have kidney or other VHL-related tumors that are growing or can be measured. The study looks at how well belzutifan works in real-world conditions and whether certain genetic factors affect how the drug works.
São Paulo, São PauloAges 14 years+ - NCT04154553Recruiting
Genetic testing to prevent bad drug reactions or treatment failures
This study looks at whether a person’s genetic makeup can help choose safer medicines or improve how well treatment works. You may be asked for testing if you’ve had a bad reaction or treatment failure, or if you’re starting a new medicine that is known to be affected by genetics.
BaselAges 2 years+ - NCT07100054Enrolling by invitation
Genetic markers for CDK4/6 inhibitor therapy in breast cancer
This trial looks at how genetic markers and other substances in your blood might help personalize treatment with CDK4/6 inhibitors, a targeted therapy for breast cancer. It aims to find better ways to predict which patients will benefit most.
London, OntarioAges 18 years+ - NCT07076082RecruitingPhase 4
Vascular trial registry for leg artery procedures
This study is a registry that collects information on people who have or will have a leg artery procedure to open blocked blood vessels. It helps doctors learn more about how well these procedures work and how to improve care.
Detroit, MichiganAges 45 years+ - NCT07046676RecruitingPhase 4
Using genetics to personalize valproate treatment for epilepsy
This trial studies how a person's genes affect their response to the epilepsy drug valproate. The goal is to find the best dose for each patient to improve seizure control and reduce side effects.
Hengyang, HunanAges Any age - NCT06935344Recruiting
Can genes predict ovarian cancer risk?
This study looks at whether a score based on your genes can predict the risk of epithelial ovarian cancer. It compares women newly diagnosed with this cancer to women who have never had it.
Roma, ItaliaAges 18 years+ - NCT05830279Recruiting
Personalized drug choices to better manage cancer treatment side effects
This trial tests a personalized approach to selecting drugs during cancer treatment. The goal is to improve how well your prescribed medicines work for symptoms and side effects while keeping you safe.
London, OntarioAges 18 years+ - NCT06789588Enrolling by invitationPhase 3
Better warfarin therapy for atrial fibrillation
This study tests a better way to manage warfarin (a blood thinner) for people with atrial fibrillation (an irregular heartbeat). The goal is to improve treatment and help prevent stroke.
Recife, PernambucoAges 18 years+ - NCT02347111RecruitingPhase 4
Genetic study to guide antiarrhythmic drugs for atrial fibrillation
This study looks at how a person’s genetics may affect how well and safely antiarrhythmic medicines work for atrial fibrillation (AF). If you join, you may get medicine options like flecainide or sotalol, and researchers compare outcomes to genetic information.
Chicago, IllinoisAges 18–100 - NCT06568601Recruiting
Genetic testing to guide statin choice for veterans
This study looks at using a genetic test to help doctors choose the best statin medicine for veterans who need to lower their cholesterol but haven't taken a statin in the last 6 months. If you have diabetes, heart disease, or have had a stroke, this trial may help find a statin that works well for you with fewer side effects.
Indianapolis, IndianaAges 40–75 - NCT06448091Recruiting
Precision Medicine in the Emergency Room
This study tests whether using genetic information in the emergency department can help choose safer medications for patients 40 and older. It focuses on people who frequently visit the ER and are starting a new long-term medication.
Gainesville, FloridaAges 40 years+
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Common questions
- Are there clinical trials for pharmacogenetics?
- Yes. Clin2 currently lists 30 recruiting pharmacogenetics studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pharmacogenetics trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pharmacogenetics trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.