Clinical trials
Pharmacogenetics clinical trials
Below are recruiting pharmacogenetics clinical trials, each written for real people, not researchers. We’re tracking 32 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06335043Recruiting
Personalized medication matching for veterans with OSI
This trial tests whether using genetic information to guide medication choices can improve treatment for veterans with operational stress injuries (OSI). It aims to help find the right medication faster and with fewer side effects.
London, OntarioAges 18 years+ - NCT04507555Recruiting
Pharmacist-guided genetic testing to choose antidepressants
This study tests whether doing genetic testing before starting or adjusting antidepressants—guided by a pharmacist—can improve treatment for people with moderate to severe depression. The goal is to help match you with antidepressants more safely and effectively.
Münchenbuchsee, Canton of BernAges 18 years+ - NCT06853587Recruiting
Genetic test to help pick antidepressant for teens
This study tests whether using a cheek swab DNA test can help choose a better antidepressant for teenagers with anxiety or depression. The goal is to see if this personalized approach leads to fewer side effects and better results.
Calgary, AlbertaAges 12–17 - NCT06929533Recruiting
Genetic testing to guide mental health medication
This study tests if using genetic information can help doctors choose the right mental health medication or dose. It may help find treatments that work better with fewer side effects.
Winnipeg, ManitobaAges 18 years+ - NCT07060300Enrolling by invitation
Genetic testing for drug reactions in complex care children
This study looks at how children with complex medical conditions respond to medicines based on their genes. It may help personalize care by testing how your child's body processes certain drugs, all from a simple cheek swab.
Cincinnati, OhioAges Any age - NCT00730678Recruiting
Study genes to learn how treatment affects children
This study looks at genetic (DNA) differences to better understand why treatments work differently for children at St. Jude. It may help doctors choose safer or more effective treatments in the future.
Memphis, TennesseeAges Any age - NCT07422090Recruiting
Preventing suicide with digital and genetic tools
This trial uses smartphone data and genetic testing to help prevent future suicide attempts. It aims to find personalized ways to support people who have already had a suicide attempt.
Madrid, MadridAges 12 years+ - NCT07388407Recruiting
Genetics of leflunomide for rheumatoid arthritis
This study looks at how your genes might affect how well leflunomide works for rheumatoid arthritis. It is for Pakistani adults who are starting or recently started leflunomide, and will help doctors understand who might respond best.
Islamabad, Punjab ProvinceAges 20–65 - NCT05071898RecruitingPhase 1
Studying how genetics affect response to GLP-1 weight-loss drugs
This early-stage study looks at how genetic factors may change how people respond to a GLP-1 medicine (semaglutide). The goal is to learn who may benefit most and why, so future treatments can be better matched.
Lancaster, PennsylvaniaAges 18–89 - NCT03953014Recruiting
Genetic study of antidepressant side effects in young people
This trial studies whether genes (using a saliva sample) can help explain why some young people feel more “disinhibited” after taking antidepressants like SSRIs. If you’ve had depression, anxiety, or OCD and have used an SSRI, your information and genetics may help improve how antidepressants are chosen and monitored.
Calgary, AlbertaAges 6–17 - NCT04154553Recruiting
Genetic testing to prevent bad drug reactions or treatment failures
This study looks at whether a person’s genetic makeup can help choose safer medicines or improve how well treatment works. You may be asked for testing if you’ve had a bad reaction or treatment failure, or if you’re starting a new medicine that is known to be affected by genetics.
BaselAges 2 years+ - NCT04623099RecruitingPhase 4
Personalized escitalopram dosing for anxious teens
This study tests whether a genetics-guided approach to choosing and adjusting escitalopram (an anxiety medicine) can improve safety and effectiveness for anxious teens. It also checks that participants have certain anxiety severity scores and can safely take the study medication.
Cincinnati, OhioAges 12–17 - NCT04964310Recruiting
Testing genetic risk for acetaminophen-related liver injury
This study looks at whether certain genes can predict who is more likely to get liver injury after taking acetaminophen (also found in some cold/flu medicines). By comparing people who were affected with people who were not, it may help doctors identify higher-risk patients in the future.
Nanjing, JiangsuAges 14 years+ - NCT05119179RecruitingPhase 4
Testing how genetics affect GLP-1 response in prediabetes
This study looks at how your genes may change how well a GLP-1–type medicine works to improve prediabetes. It focuses on adults at higher risk of developing diabetes, especially people of Mexican-American background.
Brownsville, TexasAges 18 years+ - NCT05656469Recruiting
Personalized psychiatry meds using gene test results
This study compares a personalized medication plan based on your genes versus standard dosing for people with depression, anxiety, or psychosis. It may help your clinician choose a safer or more effective dose or medicine by using pharmacogenomics (gene-informed prescribing).
Syracuse, New YorkAges 16–70 - NCT05830279Recruiting
Personalized drug choices to better manage cancer treatment side effects
This trial tests a personalized approach to selecting drugs during cancer treatment. The goal is to improve how well your prescribed medicines work for symptoms and side effects while keeping you safe.
London, OntarioAges 18 years+ - NCT06322238RecruitingPhase 2
Can a DNA test help prevent drug side effects in primary care?
This study tests whether a cheek-swab DNA test can help doctors choose safer medicines for you. If you are starting a new drug in primary care, you might join to help prevent side effects.
Rochester, MinnesotaAges 18 years+ - NCT06448091Recruiting
Precision Medicine in the Emergency Room
This study tests whether using genetic information in the emergency department can help choose safer medications for patients 40 and older. It focuses on people who frequently visit the ER and are starting a new long-term medication.
Gainesville, FloridaAges 40 years+ - NCT06527495RecruitingPhase 1/Phase 2
Genetics of Sorafenib in Liver Cancer Patients
This trial tests whether the way your body processes the drug sorafenib (used for liver cancer) affects its safety and effectiveness. It aims to find the best dose for patients based on their genetics, which could lead to better treatment outcomes.
Shibīn al Kawm, MenoufiaAges 18–80 - NCT06568601Recruiting
Genetic testing to guide statin choice for veterans
This study looks at using a genetic test to help doctors choose the best statin medicine for veterans who need to lower their cholesterol but haven't taken a statin in the last 6 months. If you have diabetes, heart disease, or have had a stroke, this trial may help find a statin that works well for you with fewer side effects.
Indianapolis, IndianaAges 40–75 - NCT06607445Recruiting
Testing a personalized medicine program in Extremadura
This study looks at a program called MedeA that uses your genes to help choose the right medicines for you. If you live in Extremadura and are starting or already on treatment, you may be able to join.
BadajozAges Any age - NCT06902688Recruiting
Pharmacogenetic testing for kids at SickKids
This trial offers pharmacogenetic testing to children admitted to The Hospital for Sick Children to help doctors choose safer, more effective medications based on their genes.
Toronto, OntarioAges 6 months–18 years - NCT06935344Recruiting
Can genes predict ovarian cancer risk?
This study looks at whether a score based on your genes can predict the risk of epithelial ovarian cancer. It compares women newly diagnosed with this cancer to women who have never had it.
Roma, ItaliaAges 18 years+ - NCT07046676RecruitingPhase 4
Using genetics to personalize valproate treatment for epilepsy
This trial studies how a person's genes affect their response to the epilepsy drug valproate. The goal is to find the best dose for each patient to improve seizure control and reduce side effects.
Hengyang, HunanAges Any age
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Common questions
- Are there clinical trials for pharmacogenetics?
- Yes. Clin2 currently lists 32 recruiting pharmacogenetics studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pharmacogenetics trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pharmacogenetics trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.