Clinical trials
Phenotype clinical trials
Below are recruiting phenotype clinical trials, each written for real people, not researchers. We’re tracking 312 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05774678RecruitingPhase 3
Pre-surgery radiation options for invasive breast cancer
This trial compares two schedules of radiation given before mastectomy to see which works better for invasive breast cancer, followed by immediate breast reconstruction. It also studies tiny “biomarker” signals in tissue to learn why one radiation approach may help more.
Houston, TexasAges 18 years+ - NCT02886611Recruiting
Study for genetic eye surface stem cell problems
This trial studies people whose eye surface problems are caused by an inherited (genetic) condition. It aims to better understand how specific genetic changes relate to symptoms, which may guide more personalized care.
ParisAges Any age - NCT05743868Recruiting
Study of how insulin resistance affects blood fats
This study looks at how differences in insulin resistance may change how the liver makes triglycerides (a type of blood fat). It may help researchers understand why some people have higher triglycerides and how to target them better.
AmsterdamAges 18–65 - NCT05578742Recruiting
Test breathing support patterns in moderate to severe ARDS
This trial studies how adjusting ventilator settings can better match the lungs’ ability to move air and oxygen in people with moderate to severe ARDS. It may help doctors tailor breathing support for different “lung mechanics” patterns, especially during the first days after intubation.
Angers, Maine et LoireAges 18 years+ - NCT05574673Recruiting
Study of DNA repair traits in ovarian cancer patients
This study looks at certain “DNA repair traits” (called homologous recombination phenotype) in people with epithelial ovarian cancer. Results may help researchers better understand who responds to platinum chemotherapy, which is commonly used for this cancer.
København Ø, Region SjællandAges 18–100 - NCT05528744Recruiting
Study genes and symptoms in ANKRD17-related CAGS
This study looks at how a specific gene change in ANKRD17 relates to the symptoms, brain/scan findings, and brain-cells in people with Chopra-Amiel-Gordon syndrome (CAGS). It may help families understand the condition better and connect gene results to what is seen clinically.
Boston, MassachusettsAges Any age - NCT05516628RecruitingPhase 2
Adjuvant atezolizumab plus bevacizumab after liver cancer surgery
This trial studies whether adding atezolizumab and bevacizumab after complete liver cancer surgery can lower the chance the cancer comes back. It also uses “multi-omics” tests (special lab tests on your tissue/blood) to help predict who is more likely to respond or resist treatment.
SingaporeAges 21–90 - NCT05473429Recruiting
Study how pain works in people with intellectual disability
This study measures how you feel pain (nociception) and compares patterns in people with intellectual disability and healthy volunteers. It may help researchers better understand pain differences and improve future pain care.
Bethesda, MarylandAges 8–30 - NCT05450783Recruiting
PET-MRI imaging study for arrhythmogenic heart disease
This study uses a special whole-heart scan (PET combined with MRI) to better understand the tissue and metabolism patterns in people with arrhythmogenic cardiomyopathy. The goal is to see whether these scan patterns relate to symptoms now and how the disease may change over time.
AngersAges 16–99 - NCT05375812Recruiting
Deep health study of Gulf War veteran symptoms and brain-body changes
This study closely measures health, thinking, and body function in Gulf War veterans using detailed testing (including exercise testing and possibly brain scans). It aims to better understand what may be driving Gulf War illness and related symptoms, which could improve future care.
Bethesda, MarylandAges 48–70 - NCT05368064Enrolling by invitation
Study of cleidocranial dysplasia care from symptoms and genetics
This study looks at cleidocranial dysplasia (CCD) using a person’s symptoms and/or genetic findings to better understand what needs care and support. It may help teams improve how CCD is recognized and managed over time.
Baltimore, MarylandAges Any age - NCT05408728Enrolling by invitation
Check how sugar absorption predicts weight loss after endoscopy
This study looks at whether a person’s “sugar absorption” pattern can help predict how much weight they will lose. It involves an endoscopy (a look inside the upper digestive tract) as part of routine care, and then matching the results to future weight change.
Jacksonville, FloridaAges 18 years+ - NCT05322850RecruitingPhase 1/Phase 2
Engineered donor stem cell transplant for childhood blood cancers
This trial tests a new way to prepare donor stem cells before a transplant for children and young adults with blood cancers. The goal is to make the transplant safer and more effective, potentially reducing complications like graft-versus-host disease.
Gainesville, FloridaAges Up to 50 years - NCT05269628RecruitingPhase 2
Cannabidiol for multiple sclerosis sleep and pain patterns
This study looks at whether cannabidiol (CBD, a cannabis-related medicine) can improve symptoms in people with multiple sclerosis (MS), especially how sleep and pain type affect outcomes. It’s mainly for people with MS and ongoing moderate-to-severe pain, while carefully checking safety and medication interactions.
Ann Arbor, MichiganAges 18–65 - NCT05213572Recruiting
Deep health check study for adults with sickle cell disease
This study looks at how major organs like the brain, kidneys, heart, and liver are affected in adults with sickle cell disease, whether they've had a bone marrow transplant or gene therapy, or are continuing regular treatment. You'll get detailed tests that can help doctors understand the disease better, which may lead to improved care.
Bethesda, MarylandAges 18–100 - NCT05229666Recruiting
Study stress patterns in early pregnancy and preterm birth risk
This study looks at how stress shows up in the body during early pregnancy and whether it’s linked to preterm birth (birth before 37 weeks). You may be asked about your stress and health to help researchers understand who is at higher risk.
New York, New YorkAges 18 years+ - NCT05072483Recruiting
Study of CADASIL’s natural course using blood tests and MRI
This study follows people with CADASIL (a genetic brain blood-vessel condition) to learn how it progresses over time. It uses blood and possibly tissue samples and brain MRI scans to better understand changes in the brain.
Bethesda, MarylandAges 18–100 - NCT05047354Recruiting
Study cholesterol metabolism in rare genetic conditions
This study looks at body chemistry (cholesterol-related lab findings) and physical features in people with Smith-Lemli-Opitz syndrome and related rare genetic cholesterol disorders. It may help researchers better understand these conditions and how they affect the body.
Bethesda, MarylandAges 1 day–100 years - NCT04989751Enrolling by invitation
Study of gene patterns in limb-girdle muscle weakness
This study looks at how specific gene changes relate to the pattern of muscle weakness in people with limb-girdle muscular dystrophy (LGMD). It may help doctors better understand the condition and improve future care.
ShanghaiAges 10 years+ - NCT04872478RecruitingPhase 1
Early-phase drug safety and dosing study for relapsed blood cancers
This Phase 1 trial tests MRX-2843 in teenagers and adults whose leukemia has come back or did not respond to prior treatment. The main goals are to find safe dosing and learn how the body processes the drug.
Atlanta, GeorgiaAges 12 years+ - NCT04103268Recruiting
Study blood tests to understand organ injury in children with sepsis
This study uses special blood testing to learn what is happening in the immune system during sepsis in children and how it may relate to organ injury. Your results may help doctors recognize and treat sepsis earlier and more accurately.
Boston, MassachusettsAges 1 month–17 years - NCT04803201RecruitingPhase 2
Adding new drugs to usual treatment for peripheral T-cell lymphoma
This trial tests whether adding one of two experimental drugs to the standard chemotherapy improves outcomes for people with certain types of peripheral T-cell lymphoma, a rare blood cancer. It aims to see if the combination is safe and effective.
Little Rock, ArkansasAges 18 years+ - NCT04793867Recruiting
MRI study of lung differences in cystic fibrosis and bronchiectasis
This study uses MRI scanning to better understand how the lungs differ in people with cystic fibrosis (CF) and in people with non-CF bronchiectasis. The results may help doctors understand disease changes over time and guide future care, especially for children and teens.
Cincinnati, OhioAges 5–100 - NCT04701177Enrolling by invitation
Smartphone-based study of brain biomarkers in memory clinic patients
This observational study follows people with (or at risk for) Alzheimer’s-related brain changes and a comparison group without them. It uses clinic visits, cognitive testing, questionnaires, and possibly a spinal fluid test to better understand brain biomarkers and how they relate to thinking and daily life.
Corfu, CorfuAges 45 years+
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Common questions
- Are there clinical trials for phenotype?
- Yes. Clin2 currently lists 312 recruiting phenotype studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a phenotype trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a phenotype trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.