Clinical trials
Pilot Study clinical trials
Below are recruiting pilot study clinical trials, each written for real people, not researchers. We’re tracking 512 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04166526Recruiting
Brain and brain-vessel MRI study in kids with sickle cell
This study uses MRI scans to understand how the brain and blood vessels are affected in children with sickle cell disease, including before and after certain treatments. It also includes healthy children for comparison and may help improve future monitoring and care.
Boston, MassachusettsAges 8–18 - NCT04180085RecruitingPhase 2
Belatacept to protect kidneys in heart transplant patients
This trial studies whether belatacept can be used after a heart transplant to help protect kidney function over time. It focuses on people who already have (or are at risk for) worsening kidney function after transplant, while avoiding those with certain infections or rejection concerns.
BordeauxAges 18 years+ - NCT04197258Recruiting
Peer support after stroke for people going home from rehab
This study tests whether a personal “peer” supporter can help you after discharge home following a stroke. It’s meant to improve how stroke patients cope and to understand what support works best.
Saint-Genis-LavalAges 18 years+ - NCT04253964RecruitingPhase 2
Chemo plus immunotherapy by lung cancer fitness level
This study compares two approaches to starting chemo plus immunotherapy in people with metastatic or unresectable non-small cell lung cancer who have different levels of daily functioning. It aims to see which approach is safer and works better for patients with lower or higher day-to-day ability.
Winston-Salem, North CarolinaAges 18 years+ - NCT04300686RecruitingPhase 4
Pilot study for severe Takayasu artery inflammation
This trial studies treatment options for people age 14 and older with severe, active Takayasu arteritis causing major circulation problems and organ strain. It may help reduce inflammation and complications when the disease is flaring and difficult to control.
Shanghai, Shanghai MunicipalityAges 14–100 - NCT04343313Recruiting
Transcatheter repair for leaky mitral valve in high-risk adults
This pilot study tests a newer catheter-based way to reduce leakage of the mitral valve in people who feel sick from mitral regurgitation but are considered too high-risk for standard surgery. If you fit the valve and heart anatomy needs, the study may help improve symptoms and valve function without open-heart surgery.
New York, New YorkAges 21–95 - NCT04393701Recruiting
Testing newborn blood spots to check for rare storage diseases
This pilot study tries a systematic way to look for several rare “lysosomal storage” diseases in newborns using a specialized lab test on routine blood samples. It may help detect these conditions earlier so treatment can start sooner if needed.
CaenAges 1 day–4 days - NCT04428515Recruiting
Photoacoustic scans for untreated head and neck cancer
This study tests a special imaging scan (photoacoustic imaging) to help doctors look at head and neck cancer before treatment. It’s for people who have not had first-line therapy yet and will be starting radiotherapy.
Toronto, OntarioAges Any age - NCT04512716RecruitingEarly Phase 1
Radioimmunotherapy then CD19 CAR T for hard-to-treat blood cancers
This early-phase study tests a two-step treatment: first a targeted radioactive antibody (131-I apamistamab) and then CD19 CAR T-cell therapy. It is for adults with relapsed or refractory B-cell acute lymphoblastic leukemia (B-ALL) or diffuse large B-cell lymphoma (DLBCL) that is not responding or has come back, aiming to shrink cancer using engineered immune cells.
Basking Ridge, New JerseyAges 18 years+ - NCT04571736Recruiting
Web and video support during thyroid surgery planning
This study tests a pre-surgery video support program and a secure website to help people prepare for thyroid surgery. It may improve understanding and follow-through by collecting your answers before the operation.
Montpellier, HéraultAges 18–75 - NCT04655404RecruitingEarly Phase 1
Larotrectinib for children with newly diagnosed glioma with NTRK fusion
This trial tests larotrectinib, a targeted cancer medicine, in children and teens with newly diagnosed high-grade brain glioma that has an NTRK fusion. It may help shrink or control tumors by targeting a specific genetic change in the cancer.
Aurora, ColoradoAges Up to 21 years - NCT04701723Recruiting
Breathing training to help after trauma stress
This pilot study tests whether “cardiac coherence” breathing exercises can help prevent ongoing (chronic) post-traumatic stress disorder after a recent traumatic event. It’s meant for people who are newly dealing with an acute stress reaction, soon after the event.
Saint-PaulAges 18 years+ - NCT04706026Recruiting
Local numbing during groin hernia surgery in older adults
This study tests whether using local numbing (rather than general anesthesia) during groin hernia surgery is safe and effective for older adults. It may help improve comfort and reduce anesthesia-related risks in people who qualify.
Dallas, TexasAges 60 years+ - NCT04722029RecruitingPhase 1/Phase 2
Donor immune-cell therapy for stubborn adenovirus infections
This study tests whether specially matched donor T-cells can control “refractory” adenovirus (a virus) that isn’t responding to usual antiviral medicines. It may help if the infection keeps coming back or is already affecting organs like the lungs or bowel.
Columbus, OhioAges Up to 60 years - NCT04746820Recruiting
Brain monitoring in unconscious ICU patients after cardiac arrest
This trial tests a bedside brain-monitoring method (near-infrared light and EEG) in people who are unconscious after severe brain injury from cardiac arrest. The goal is to see whether it can help measure brain function during the first week after admission.
Zurich, Canton of ZurichAges 18 years+ - NCT04756245Recruiting
Pilot study using virtual reality plus walking support
This study tests a virtual reality activity program you can do at home, with support from an “activity buddy.” It aims to see whether the program is safe and workable for people at home, and to learn how it affects activity and thinking.
Winston-Salem, North CarolinaAges 45–80 - NCT04764331Recruiting
Red light cap for scar-forming hair loss in women
This pilot study tests an “all LED” red light cap to treat central centrifugal cicatricial alopecia (CCCA), a type of scarring hair loss. If you’re a woman with confirmed CCCA at Stage II–III and stable treatment, the study may help see whether red light can improve your hair loss without changing your current plan.
Winston-Salem, North CarolinaAges 18–75 - NCT04770025RecruitingPhase 2
Brain stimulation with therapy for risky alcohol use
This study tests whether a non-invasive brain stimulation device can make standard psychotherapy work better for people who drink in a risky way. It’s designed for community participants who are not already in alcohol-use treatment.
Albuquerque, New MexicoAges 21–60 - NCT04771507RecruitingPhase 1/Phase 2
Testing intermittent ibrutinib for advanced chronic lymphocytic leukemia
This trial studies whether taking ibrutinib in a less continuous (“intermittent”) schedule can keep your chronic lymphocytic leukemia (CLL) under control. It’s for people who have already received ibrutinib for at least 6 months and had a good early response, aiming to reduce treatment intensity while tracking safety and cancer control.
TrondheimAges 18 years+ - NCT04783103Recruiting
Brain scan study of stimulation for depression in older adults
This is a pilot study that uses brain imaging to see how a brain “neuromodulation” approach may affect depression in people age 65 and older. You would be screened for depression severity, medication history, and safety limits, and then be asked to keep your depression medicines stable during the study.
Jette, Brussels CapitalAges 65 years+ - NCT04814420Recruiting
Study heart scarring in sleep apnea, with or without atrial fibrillation
This pilot study looks at whether obstructive sleep apnea leads to heart scarring (called atrial fibrosis), especially in people with and without an irregular heart rhythm (atrial fibrillation). It may help researchers understand who is at higher risk and why, using sleep testing and heart imaging.
New Orleans, LouisianaAges 18–75 - NCT04886245Recruiting
Eye-tracking study of face attention in facial paralysis
This pilot study uses an eye-tracking camera to measure where people look when viewing faces. It compares attention patterns in adults with facial paralysis to healthy adults, which may help improve understanding and support for people affected.
AmiensAges 18 years+ - NCT07699393RecruitingPhase 2
Choline supplement study for healthy pregnancies
This trial tests whether taking extra choline (a nutrient similar to B vitamins) during pregnancy can improve health for mothers and babies. You may be eligible if you are early in a singleton pregnancy and do not drink alcohol.
Cape TownAges 18–45 - NCT07145866RecruitingPhase 4
Varenicline and TMS for quitting nicotine use
This study tests whether combining the medication varenicline (Chantix) with a special brain stimulation treatment (TMS) can help people quit vaping or smoking nicotine. If you're motivated to quit and use nicotine daily, you may be able to join.
Boston, MassachusettsAges 18–65
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Common questions
- Are there clinical trials for pilot study?
- Yes. Clin2 currently lists 512 recruiting pilot study studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pilot study trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pilot study trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.