Clinical trials
Placebo - Control clinical trials
Below are recruiting placebo - control clinical trials, each written for real people, not researchers. We’re tracking 3,902 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04438213RecruitingPhase 2
Ertugliflozin for chronic heart failure with added urine testing
This Phase 2 trial studies whether the medication ertugliflozin can help people with chronic heart failure. You would be asked to follow a set treatment plan and complete repeated urine (and other) testing to see how your body responds.
New Haven, ConnecticutAges 18 years+ - NCT06133972RecruitingPhase 3
Long-term safety of ianalumab for lupus (extension study)
This extension study tests the long-term safety of ianalumab for people with systemic lupus erythematosus. If you completed a prior SIRIUS-SLE study and your doctor thinks you'd benefit, you may continue treatment for up to 60 more weeks.
Anniston, AlabamaAges 12–100 - NCT06150742Recruiting
Nafamostat for dialysis patients who can't use heparin
This trial tests a new medicine called nafamostat to prevent blood clots during continuous dialysis (CRRT), for people who are at high risk of bleeding or can't take heparin.
Los Angeles, CaliforniaAges 18–80 - NCT06131983Enrolling by invitationPhase 1/Phase 2
Study of SRP-1001 for adults and teenagers with FSHD1
This study tests a new medicine called SRP-1001 to see if it can help people with a type of muscular dystrophy called FSHD1. It aims to slow down muscle weakness and improve quality of life.
Liverpool, New South WalesAges 16–70 - NCT06150560RecruitingPhase 3
Blood pressure medicine study for people with repaired coarctation of the aorta
This trial tests a type of blood pressure medicine (an angiotensin-II receptor blocker) to see if it can help prevent changes in the heart's structure. It is for people who have had surgery for a coarctation of the aorta and now have mild to moderate high blood pressure.
Rochester, MinnesotaAges 18 years+ - NCT06137365RecruitingPhase 2
Cannabis for Obesity Treatment Study
This study tests whether a cannabis product can help with weight loss in people with obesity. It is for those who have not used cannabis recently and are generally healthy.
Lexington, KentuckyAges 18–65 - NCT06139224Recruiting
Gut Bacteria and Inflammation in HIV and Heavy Drinking
This study looks at how gut bacteria and inflammation interact in people with both HIV and heavy alcohol use. It aims to find new ways to improve health by understanding these connections.
Chicago, IllinoisAges 45–75 - NCT06152328Recruiting
Virtual reality mirror therapy for arm recovery after stroke
This study tests whether virtual reality mirror therapy can help people recover arm movement after a stroke. It is for people who had an ischemic stroke a few months ago and still have some arm weakness.
Bolu, MerkezAges 40–80 - NCT06143631RecruitingPhase 4
Letrozole study for uterine fibroids
This trial tests if the drug letrozole can improve symptoms like heavy bleeding and pelvic pain caused by uterine fibroids. You must be premenopausal with moderate to severe symptoms and not have very large fibroids or certain other conditions.
Los Angeles, CaliforniaAges 21–53 - NCT06152991Enrolling by invitationPhase 3
Godex for fatty liver: a Phase 3 trial
This study tests an investigational supplement called Godex Carnitine Orotate Complex to see if it helps people with nonalcoholic fatty liver disease (NAFLD) lower their liver enzymes and reduce liver fat. It may be a good option if you have elevated liver enzymes and evidence of fat in your liver.
SeoulAges 19–74 - NCT06130059RecruitingPhase 2
Low-dose colchicine for heart failure with inflammation
This trial tests whether a low-dose colchicine (LoDoCo) can help people with heart failure and inflammation feel better and exercise more. It is for adults 50 and older with HFpEF who have signs of inflammation in their blood.
Dallas, TexasAges 50 years+ - NCT06148311Enrolling by invitationPhase 2
Dexmedetomidine film for autonomic crises in Familial Dysautonomia
This study tests a new dissolvable film containing dexmedetomidine (a medicine that calms overactive stress responses) for people with Familial Dysautonomia who experience sudden episodes called autonomic crises. It aims to treat these crises at home without needing a hospital visit.
New York, New YorkAges 16–80 - NCT02897063RecruitingPhase 1
Test medicines for low blood pressure in nerve-related disorders
This early (Phase 1) study tests whether midodrine and droxidopa can improve blood-flow pooling in the belly in people with nerve problems that affect blood pressure when standing. It’s looking at safety and how the body responds, which may help reduce dizziness or fainting for some participants.
Nashville, TennesseeAges 40–80 - NCT06128629RecruitingPhase 3
A study of NTLA-2001 for transthyretin amyloidosis with heart problems
This study tests a new treatment, NTLA-2001, for people with a type of heart disease called transthyretin amyloidosis with cardiomyopathy. It aims to see if the medicine can help improve heart function and quality of life.
Tucson, ArizonaAges 18–90 - NCT06119581RecruitingPhase 3
Oloromosib with Immunotherapy as First Treatment for KRAS G12C Lung Cancer
This trial tests a new targeted pill (olomorasib) combined with immunotherapy (pembrolizumab) and possibly chemotherapy for people with advanced non-small cell lung cancer that has a KRAS G12C mutation and has not been treated before.
Huntsville, AlabamaAges 18 years+ - NCT06122207Recruiting
Probiotic for women with fertility issues and IVF
This study tests whether a probiotic (a pill with beneficial bacteria) can help improve the health of the female genital tract for people with fertility problems who are undergoing IVF. It aims to see if this can improve chances of pregnancy.
LisbonAges 18–45 - NCT06129175RecruitingPhase 2/Phase 3
Stem cells for recent moderate to severe stroke
This trial is testing a new treatment using stem cells from donated umbilical cord tissue to help people recover from a recent moderate to severe stroke. It is for patients who cannot receive standard clot-busting treatments.
Cheras, Kuala LumpurAges 18 years+ - NCT06104839RecruitingPhase 2
Oral NXC-736 for moderate to severe alopecia areata
This trial tests an oral medication called NXC-736 for people with moderate to severe alopecia areata. It aims to see if the drug is safe and can help regrow hair.
SeoulAges 19–65 - NCT06123754RecruitingPhase 3
Envafolimab plus chemo for stage III NSCLC before surgery
This trial tests a new immunotherapy (Envafolimab) combined with standard chemotherapy before and after surgery for stage III non-small cell lung cancer that can be removed. The goal is to see if adding Envafolimab helps shrink the tumor and improve outcomes compared to chemotherapy alone.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT06127407RecruitingPhase 3
Ivosidenib for advanced chondrosarcoma with IDH1 mutation
This trial tests an experimental drug called ivosidenib for people with a specific type of bone cancer (chondrosarcoma) that has spread or can't be removed with surgery. The drug targets a genetic change (IDH1 mutation) found in some chondrosarcomas. It may help slow or stop tumor growth.
Los Angeles, CaliforniaAges 18 years+ - NCT05846399RecruitingPhase 4
Test antibiotic prevention after a cat bite to the hand
This study tests whether taking a specific antibiotic right after a cat bite to the hand or forearm can help prevent an infection. You may be eligible if you arrive within 24 hours and don’t already have signs of infection.
Columbia, MissouriAges 18 years+ - NCT06010719RecruitingPhase 4
Azithromycin for severe malnutrition in children
This study tests whether adding the antibiotic azithromycin to standard nutritional care helps young children with severe acute malnutrition recover better. It is for children aged 6 to 59 months in Burkina Faso who have uncomplicated malnutrition and are not currently on antibiotics.
Nouna, KossiAges 6 months–4.9 years - NCT06107062RecruitingPhase 2
CBD treatment for cannabis concentrate users
This trial tests CBD as a potential treatment for heavy cannabis concentrate users who want to cut down or quit. You would take CBD daily and attend regular visits to track your progress.
Boulder, ColoradoAges 21 years+ - NCT06123715RecruitingPhase 2
Vitamin C to reduce pain after knee replacement
This study tests whether taking vitamin C before and after knee replacement surgery can reduce long-term pain. You may be eligible if you are having knee replacement for osteoarthritis and are generally healthy.
Toronto, OntarioAges 18 years+
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Common questions
- Are there clinical trials for placebo - control?
- Yes. Clin2 currently lists 3,902 recruiting placebo - control studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a placebo - control trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a placebo - control trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.