Clinical trials
Placebo - Control clinical trials
Below are recruiting placebo - control clinical trials, each written for real people, not researchers. We’re tracking 3,962 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05477459RecruitingPhase 2
LSD treatment for reducing the burden of cluster headaches
This Phase 2 trial tests LSD to see if it can reduce how much cluster headaches disrupt your life. You may be eligible if your cluster headaches are frequent and steady, and if you meet key safety and mental-health requirements.
LeidenAges 16–75 - NCT05481879RecruitingPhase 1/Phase 2
Study medicine for DM1 to improve muscle function
This early-stage study tests DYNE-101 to see how safe it is and whether it can improve measurable muscle function in people with myotonic dystrophy type 1 (DM1). You may be asked to do several walking and strength tests and undergo heart and breathing screening measurements.
Stanford, CaliforniaAges 18–65 - NCT05484128Recruiting
Probiotic for kids taking acid-reducing medicine
This trial studies whether a specific probiotic (Lactobacillus reuteri) is helpful for children who need acid-reducing medicine for reflux or stomach discomfort. It may help improve stomach symptoms while they are on or need treatment with proton pump inhibitors.
BariAges 1–14 - NCT05487092Recruiting
Letrozole to help prevent endometrioma coming back after surgery
This study tests whether taking letrozole after laparoscopic ovarian cyst surgery can lower the chance that an endometrioma (a type of ovarian endometriosis cyst) comes back. It may help some people reduce recurrence after the cyst is removed.
Hong KongAges 18–45 - NCT05487391RecruitingPhase 3
QL1706 plus chemo after lung cancer surgery
This trial studies whether a study drug called QL1706 added to standard platinum chemotherapy can lower the chance of lung cancer coming back after surgery. It targets people with stage II to IIIB non-small cell lung cancer who have had their tumor fully removed.
ShanghaiAges 18 years+ - NCT05488431RecruitingPhase 2
Bempedoic acid to lower cholesterol and inflammation in HIV
This Phase 2 trial studies whether bempedoic acid can lower cholesterol and inflammation in people with HIV who are already on effective HIV medications. It may help reduce signs of artery inflammation that can contribute to heart and stroke risk.
Los Angeles, CaliforniaAges 40 years+ - NCT05500170Recruiting
Study of nicotinamide riboside for sleep and thinking
This trial tests whether nicotinamide riboside can improve sleep quality and help with thinking and memory. You may be invited if your sleep is poor and you do not show signs of dementia on a brief mental test.
Buffalo, New YorkAges 65–85 - NCT05501678RecruitingPhase 2
Diphenhydramine to help sleep in autistic children
This Phase 2 study tests whether diphenhydramine improves sleep in children with autism who have significant sleep problems. It requires sleep monitoring (watch data and sleep testing) and checking for side effects to see if the treatment is safe and helpful.
Stanford, CaliforniaAges 8–17 - NCT05509257RecruitingEarly Phase 1
Naltrexone and brain scans for teens with eating disorders
This early study tests whether naltrexone (a prescription medicine) changes brain activity measured by MRI in teens and young adults with binge eating and/or purging. It may help researchers understand how the brain works in these eating disorders and whether this treatment could be helpful.
Kansas City, MissouriAges 13–21 - NCT05512234Recruiting
Probiotic drops to reduce crying in breastfed baby colic
This trial tests whether probiotic Limosilactobacillus reuteri (a specific friendly gut bacteria) can shorten how long a baby cries when they have colic. If you join, you’ll keep feeding as usual and track crying in a diary across several visits.
CorkAges 3 weeks–2 months - NCT05515770RecruitingPhase 3
Injectable PrEP shot for HIV prevention in higher-risk adults
This Phase 3 study tests whether an injectable HIV prevention medicine (cabotegravir) given before exposure can help prevent HIV in people at higher risk. You may join if you are HIV-negative and meet specific sexual health, medication, and health-testing requirements.
Rio de JaneiroAges 18–30 - NCT05516472RecruitingEarly Phase 1
Fecal transplant study for people with frequent kidney stones
This trial tests whether transplanting donated stool microbiome (fecal microbiota transplantation) can change gut bacteria and help reduce harm from frequent kidney stones. You would provide urine and stool samples and have follow-up checks to watch for side effects.
Park City, UtahAges 18–69 - NCT05516862Recruiting
Find the best acupuncture for PTSD recovery
This trial tests different kinds of acupuncture to help people with PTSD (post-traumatic stress disorder). It aims to find which acupuncture approach leads to better recovery over the study period.
Nellis Air Force Base, NevadaAges 18–74 - NCT05517928Recruiting
Probiotic trial to help gut changes caused by acid-reducing pills
This study tests whether a probiotic called Lactobacillus rhamnosus GG can improve gut bacteria changes caused by proton pump inhibitors (acid-reducing medicines). It mainly involves people who are otherwise healthy and do not currently have ongoing stomach or gut symptoms.
Scottsdale, ArizonaAges 18 years+ - NCT05519254RecruitingPhase 3
Lactoferrin and lysozyme for lasting diarrhea in young children
This trial tests whether a supplement (lactoferrin and lysozyme) can help children who have long-term effects after diarrhea. It’s designed for children ages 6 to 24 months and checks whether improving gut recovery can reduce ongoing problems.
Homa BayAges 6 months–2 years - NCT05519475RecruitingPhase 2
Gene-silencing medicine trial for adults with MASH and liver scarring
This Phase 2 study tests a gene-silencing treatment to improve chronic liver disease called MASH, especially in people with certain genetic risk. You may be eligible if you have MASH with moderate-to-advanced scarring and specific test results, and if other liver causes and recent substance/alcohol issues don’t apply.
Chandler, ArizonaAges 18–75 - NCT05521711Recruiting
Testing an at-home route for tree nut allergy immunotherapy
This study tests how a specific form of treatment is given to people with a tree nut allergy. The goal is to find a safer, more effective way to help your body tolerate tree nuts.
Hamilton, OntarioAges 1–16 - NCT05524649Recruiting
Probiotics for healthy newborns’ poop bacteria balance
This study looks at whether giving probiotics to healthy newborns changes the bacteria in their stool. It may help researchers understand early gut health, but it is only for babies who meet specific health and timing requirements.
Alcaldía Coyoacán, PueblaAges 1 day–3 months - NCT05529927RecruitingPhase 2
Dexamphetamine given long-acting to reduce cocaine use
This Phase 2 study tests whether a long-acting form of dexamphetamine can reduce cocaine use in people with moderate to severe cocaine use disorder. It also checks safety, including heart and mental health side effects, while you attend study visits regularly.
The HagueAges 18 years+ - NCT05539729RecruitingPhase 1
Testing vancomycin for newly diagnosed multiple sclerosis
This Phase 1 study tests whether the antibiotic vancomycin can be given safely to people with newly diagnosed multiple sclerosis (or related early stages). It mainly focuses on safety and side effects, and whether the approach is feasible for this group.
New York, New YorkAges 18–50 - NCT05540288RecruitingPhase 3
Nalmefene vs placebo to reduce cravings in behavioral addictions
This study tests whether nalmefene, a non-opioid medicine, can reduce craving episodes in people with behavioral addictions like gambling, food addiction, or sexual addiction. Participants keep tracking cravings weekly, and compare the nalmefene effect against a placebo in addition to their usual care.
BesançonAges 18 years+ - NCT05540574RecruitingPhase 2
Zolpidem for sleep problems in autistic children
This Phase 2 study tests zolpidem (a sleep medicine) to help children with autism sleep better. It will check sleep changes using sleep testing and to confirm zolpidem is safe for this age group.
Stanford, CaliforniaAges 8–17 - NCT05543681RecruitingPhase 2
Study drug for agitation in Alzheimer’s dementia with caregiver support
This Phase 2 trial tests a study medicine to reduce “agitation” behaviors in people with Alzheimer’s dementia. You and your caregiver would complete required assessments and may need genetic and blood testing to check how the body handles the drug.
Maitland, FloridaAges 60 years+ - NCT05545605Recruiting
Sodium oligomannate to prevent thinking problems after stroke
This trial tests whether sodium oligomannate can help prevent or lessen memory and thinking problems that can happen after a first stroke. It may help people who are recently hospitalized for ischemic stroke and have mild cognitive decline risk.
Guangzhou, BaiyunAges 18–80
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Common questions
- Are there clinical trials for placebo - control?
- Yes. Clin2 currently lists 3,962 recruiting placebo - control studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a placebo - control trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a placebo - control trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.