Clinical trials
Placebo clinical trials
Below are recruiting placebo clinical trials, each written for real people, not researchers. We’re tracking 5,245 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04381143RecruitingPhase 4
Aspirin to prevent problems in people on dialysis
This trial studies whether taking aspirin can reduce heart and clot-related complications in adults receiving long-term dialysis. It may help by improving blood clotting behavior, but it also requires that aspirin is safe for you.
Fuzhou, FujianAges 18 years+ - NCT04395196RecruitingPhase 2
Prenatal choline for pregnancy after alcohol exposure
This trial tests whether taking a choline supplement during pregnancy can reduce harmful effects on the baby when a person drinks heavily while pregnant. It may help support healthier pregnancy and baby outcomes for those who meet the study’s drinking and nutrition criteria.
Cape Town, Western CapeAges 18–45 - NCT04399707Recruiting
Nerve-pain device study for pain after C-section
This study tests whether a small skin electrical nerve stimulator (called TENS) can reduce pain after a planned or not-urgent C-section. You may be more likely to have less pain and use fewer pain medicines if the TENS helps you.
Honolulu, HawaiiAges 18 years+ - NCT04411225RecruitingPhase 3
CBD may help early psychosis along with usual treatment
This Phase 3 trial tests whether taking cannabidiol (CBD) can reduce symptoms when added to standard care for early psychosis (like first-episode psychosis or attenuated psychosis). It may help some people have fewer troubling thoughts or perceptions over time.
La Jolla, CaliforniaAges 16–30 - NCT04414215Recruiting
Emotion-focused brain training for schizophrenia or schizoaffective disorder
This study tests a structured cognitive (thinking/skill) training program aimed at improving how people manage emotions. It may help by teaching emotion regulation skills alongside existing care.
Athens, GeorgiaAges 18–60 - NCT04419272RecruitingPhase 4
Methylphenidate for thinking problems in adults with focal seizures
This trial studies whether methylphenidate (a stimulant medicine) can improve thinking and memory problems related to epilepsy. You may be kept on your usual seizure medicines, and your thinking will be tested over about 16 weeks.
Miami, FloridaAges 18 years+ - NCT04430790RecruitingPhase 3
Doxapram for apnea in very preterm babies on breathing support
This trial studies whether the medicine doxapram can better treat breathing pauses (apnea) in very preterm babies who are already on breathing support in the NICU. It aims to reduce the need for extra interventions and improve outcomes in this high-risk group.
Brussels, Avenaue Hippocrate 10Ages 5 months–7 months - NCT04432883Recruiting
Brain stimulation to improve speech after stroke aphasia
This trial tests whether targeted mild brain stimulation (tDCS) can improve speech therapy results for people with long-lasting (chronic) aphasia after a stroke. It may help strengthen naming and communication when added to standard speech-language treatment.
Albuquerque, New MexicoAges 25–85 - NCT04433572RecruitingPhase 3
Temsirolimus treatment to improve below-knee artery procedures
This trial studies whether delivering a medicine called temsirolimus directly into the artery during a below-knee revascularization procedure can improve blood flow and outcomes. It may help people with severe leg artery disease who have symptoms like pain while walking or threatened limb tissue loss.
Houma, LouisianaAges 18 years+ - NCT04435990RecruitingPhase 3
Allergy shots for dust mites in teens and adults
This Phase 3 study tests whether dust-mite allergy treatment (likely allergy shots) can reduce allergy symptoms and improve safety. It focuses on people whose nose/eye allergy is triggered by house dust mites and who may also have controlled asthma.
Santiago de Compostela, A CoruñaAges 12–65 - NCT04436081RecruitingPhase 2
CBD oil without THC for agitation in Alzheimer’s dementia
This trial studies whether a THC-free CBD oil softgel can reduce agitation in people with Alzheimer’s-related dementia. It compares CBD to a control to see if it improves difficult behaviors and is safe over the study period.
Norfolk, VirginiaAges 50–90 - NCT04438213RecruitingPhase 2
Ertugliflozin for chronic heart failure with added urine testing
This Phase 2 trial studies whether the medication ertugliflozin can help people with chronic heart failure. You would be asked to follow a set treatment plan and complete repeated urine (and other) testing to see how your body responds.
New Haven, ConnecticutAges 18 years+ - NCT04442191RecruitingPhase 2
Convalescent plasma for hospitalized COVID-19 patients over 40
This trial tests whether donated “recovered patient” plasma (antibodies from people who had COVID-19) can improve outcomes for people hospitalized with COVID-19. It focuses on patients early in their illness who need a small amount of oxygen.
Chicago, IllinoisAges 40 years+ - NCT04447911RecruitingPhase 4
Empagliflozin for chronic low blood sodium in certain fluid states
This trial studies whether empagliflozin, a blood-sugar–related medicine, can safely improve chronic low blood sodium when you are not too “dry” or have an imbalanced fluid state. It may help stabilize sodium levels and related health symptoms, but you must meet specific blood and organ-function criteria.
WürzburgAges 18 years+ - NCT04449198RecruitingEarly Phase 1
Study for mitochondrial and blood-vessel issues in type 1 diabetes
This early study looks at how a new approach may affect energy-making (mitochondria) and blood-vessel signaling in people with insulin-dependent type 1 diabetes. It may help researchers understand whether these pathways can be improved in type 1 diabetes.
Augusta, GeorgiaAges 18 years+ - NCT04452500RecruitingPhase 2
Study drug for PTSD symptoms in Veterans
This trial tests a study medicine that blocks the effects of cortisol (a stress hormone) to reduce PTSD symptoms in Veterans. It’s meant for people with ongoing PTSD symptoms and stable treatments, and it closely checks safety because the medicine can affect sleep, mood, and heart rhythm.
Tuscaloosa, AlabamaAges 18–69 - NCT04458545RecruitingPhase 1/Phase 2
Opioid vaccine study for adults with heroin or fentanyl use
This trial tests a vaccine made from parts designed to help the body respond to opioids (heroin or fentanyl). It is mainly for adults with moderate-to-severe opioid use disorder who are using opioids that match the study dosing needs and who are willing to do frequent visits over about a year.
Eatontown, New JerseyAges 18–59 - NCT04479072RecruitingPhase 4
Aspirin for preeclampsia during delivery
This trial tests whether taking aspirin during pregnancy around the time of delivery helps people with preeclampsia. You may be asked to take aspirin as part of a study plan, with monitoring to see how you do.
Chicago, IllinoisAges 18–45 - NCT04490720Recruiting
Buckwheat husk extract for heart risk factors
This trial studies whether buckwheat husk extract can improve certain heart-related measurements in people with mildly high blood pressure. It may help lower cardiovascular risk factors by affecting things like blood pressure.
TaipeiAges 20–65 - NCT04496895Recruiting
Orange peel drink study for reducing body fat
This trial looks at whether a fermented orange peel product can lower body fat in adults. It may help if you have higher body fat and/or fatty liver, and you meet safety and health limits.
Taipei, TaiwanAges 20–65 - NCT04500665RecruitingPhase 2
Colchicine for kidney-related heart inflammation
This Phase 2 trial tests whether colchicine can reduce inflammation and improve heart function in people with kidney disease and a certain type of heart problem. If you qualify, you’ll be closely monitored for side effects and lab changes.
Boston, MassachusettsAges 21–80 - NCT04500847RecruitingPhase 1
Testing repurposed HIV-like drugs for early Alzheimer’s symptoms
This Phase 1 study tests whether an existing type of anti-viral medicine (nucleoside reverse transcriptase inhibitors) can help people with early Alzheimer’s disease. It also focuses on safety and proper dosing while measuring brain-related changes and memory-related symptoms.
Los Angeles, CaliforniaAges 50–85 - NCT04501406RecruitingPhase 2
Low-dose pioglitazone for fatty liver disease in people with type 2 diabetes
This Phase 2 study tests whether low-dose pioglitazone can improve NASH, a type of fatty liver disease, in adults who also have type 2 diabetes. You may be able to join if your diabetes medicines and lab tests meet specific safety and stability requirements.
Gainesville, FloridaAges 21–75 - NCT04504123RecruitingPhase 2
Doxycycline eye treatment for persistent wet macular degeneration fluid
This trial tests whether an “MMP-9 inhibitor” medicine given as doxycycline (a tetracycline-type antibiotic) can reduce persistent leaking and fluid in wet age-related macular degeneration. It may help people whose wet AMD is not fully controlled even after several anti-VEGF injections.
Iowa City, IowaAges 50–99
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Common questions
- Are there clinical trials for placebo?
- Yes. Clin2 currently lists 5,245 recruiting placebo studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a placebo trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a placebo trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.