Clinical trials
Placebo clinical trials
Below are recruiting placebo clinical trials, each written for real people, not researchers. We’re tracking 5,245 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05282550RecruitingPhase 2
Trazodone trial to improve sleep in early Alzheimer’s
This study tests whether the sleep medicine trazodone can improve thinking and memory in people with early Alzheimer’s-related changes who also have sleep problems. If better sleep helps the brain, it may improve memory test results over time.
Baltimore, MarylandAges 55 years+ - NCT05283382RecruitingEarly Phase 1
Cannabidiol trial for learning and anxiety
This early-phase study tests how cannabidiol (CBD) affects learning and anxiety. You may be able to join if you meet age and health requirements and have not used CBD or other cannabis recently.
Storrs, ConnecticutAges 18–50 - NCT05285683RecruitingPhase 2
Study brain dopamine in people with chronic pain
This Phase 2 study looks at how a brain chemical called dopamine is involved in long-lasting pain. You may be able to join if you have chronic pain for over a year and your pain score is high enough, and if MRI and health checks are safe for you.
Rochester, New YorkAges 18 years+ - NCT05288179RecruitingPhase 3
Pirfenidone capsules for silicosis or coal dust lung disease
This Phase 3 trial tests whether pirfenidone slows or improves lung damage in people with silicosis or coal worker’s pneumoconiosis. It looks at both effectiveness and side effects, and uses lung function tests and lung scans to track changes over time.
BeijingAges 18–70 - NCT05292001RecruitingPhase 4
Single IV iron dose for anemia after leg or pelvic fractures
This trial tests whether giving a one-time IV iron treatment can improve anemia (low blood count) after surgery for a leg or pelvic fracture. It may help your body make red blood cells faster after blood loss from the injury and operation.
Portland, OregonAges 18–89 - NCT05293600RecruitingPhase 1/Phase 2
Rescue medicine trial for sleep apnea after other treatments fail
This trial studies a “rescue” set of medicines for obstructive sleep apnea when two common treatments haven’t worked well enough. If you still have frequent breathing pauses during sleep, the study may test whether these medicines can reduce them and improve safety and symptoms.
Boston, MassachusettsAges 21–70 - NCT05302999RecruitingPhase 4
Early gabapentin for recovery after spinal cord injury
This trial studies whether starting gabapentin within 5 days after a traumatic spinal cord injury is safe and helpful for early recovery. It will mainly look at feasibility—whether patients can take the medicine and whether it affects early neurologic progress.
Cleveland, OhioAges 18 years+ - NCT05305911RecruitingPhase 2
SGLT2 drug after first heart attack to reduce heart damage
This Phase 2 trial tests whether an SGLT2 medicine started after a first STEMI heart attack can reduce ongoing heart muscle injury and scarring. It may help people who, based on heart imaging, have larger infarcts and ongoing microvascular damage.
Minneapolis, MinnesotaAges 18–75 - NCT05312424RecruitingPhase 1/Phase 2
Testing an annatto-based treatment for statin muscle pain
This early-stage trial tests whether an annatto-derived product (called GG) can help people who develop new muscle pain after starting or increasing a statin. If you recently noticed statin-related muscle aches, this study may see whether the treatment improves symptoms and safety.
Lubbock, TexasAges 40 years+ - NCT05312892RecruitingPhase 1/Phase 2
Study for weight-related hormone signals in people with high blood pressure
This early-phase study looks at how the body’s “fight-or-flight” signals may be involved in weight gain (obesity) and high blood pressure. It may help researchers understand the biology and guide future treatments.
Nashville, TennesseeAges 18–65 - NCT05315726Recruiting
Vibration therapy to reduce stiffness after stroke
This trial studies whether regular muscle vibration can reduce post-stroke muscle stiffness and improve how the brain and nerves adapt. If you’re in the right stage after stroke, it may help improve arm and hand movement.
Chalon-sur-SaôneAges 18 years+ - NCT05322213RecruitingPhase 1
THC study for blood sugar control in type 2 diabetes
This early-phase study tests how THC (the main cannabis ingredient) affects blood sugar levels in people with type 2 diabetes. It may help researchers understand whether THC changes glucose control and what risks come with it.
La Jolla, CaliforniaAges 21–70 - NCT05321875RecruitingPhase 3
Candesartan to prevent heart failure in certain gene carriers
This trial tests whether candesartan (a blood-pressure medicine) can delay or prevent heart muscle weakening in people who carry a disease-causing dilated cardiomyopathy gene variant but still have fairly strong heart pumping. Participants are randomly assigned to candesartan or a placebo to see which one keeps the heart healthier over time.
Majadahonda, MadridAges 18–64 - NCT05324475Recruiting
Nutritional supplement to support immunity and energy in older adults
This trial tests whether a safe nutrition supplement can help older adults with malnutrition maintain immune function and energy (mitochondrial function). It may support recovery during rehabilitation, but you must meet specific nutrition and health criteria.
Lausanne, SwitzerlandAges 75 years+ - NCT05325580RecruitingPhase 3
IV magnesium vs placebo for sudden non-injury headaches
This trial tests whether giving magnesium sulfate through a vein in the emergency room can reduce sudden (non-injury) acute headaches compared with a placebo. It may help people whose headache comes on suddenly and is not caused by an injury.
MonastirAges 18–85 - NCT05327699RecruitingEarly Phase 1
Ketamine study for depression with reduced pleasure
This early-phase study tests whether ketamine can help people with major depression who have trouble feeling pleasure. It also studies how the brain may change in response to stress, to better understand who might respond to treatment.
Atlanta, GeorgiaAges 18–65 - NCT05332067RecruitingPhase 2
Omalizumab to prevent future asthma flare-ups before they start
This trial studies whether starting omalizumab before asthma flare-ups begin can reduce how often children get worsening asthma that needs strong steroid medicine. It is for children with persistent asthma who have signs of allergic/asthma triggers and recent flare-up history.
Washington D.C., District of ColumbiaAges 6–17 - NCT05337566Recruiting
Extra antibiotic before hysterectomy to prevent infections
This trial tests whether giving extra antibiotic (azithromycin) before hysterectomy can lower the chance of infections after surgery. You might benefit by helping prevent post-surgery infection, but it also depends on your allergy history and heart rhythm risks.
HelsinkiAges 18 years+ - NCT05341583RecruitingPhase 3
Ensartinib after lung cancer surgery for ALK-positive patients
This Phase 3 trial tests whether ensartinib given after surgery can lower the risk of lung cancer coming back in people with ALK-positive non-small cell lung cancer. You may be eligible if your tumor was completely removed and your recovery and lab tests meet specific requirements.
TianjinAges 18 years+ - NCT05349006RecruitingPhase 3
Azathioprine for first attack in MOG antibody disease
This Phase 3 trial studies whether azathioprine can help prevent problems after a first attack of MOG antibody–related inflammation of the brain/spinal cord. It’s for adults with a recent first episode and confirmed MOG antibodies.
BordeauxAges 18 years+ - NCT05350371RecruitingPhase 1/Phase 2
Testing pirfenidone to treat severe acute pancreatitis
This early-stage hospital study tests whether pirfenidone is safe and tolerable for people with acute pancreatitis that may become severe. It may help by reducing the risk of complications, while researchers carefully track side effects.
Birmingham, AlabamaAges 18–85 - NCT05351229RecruitingPhase 4
Spinal morphine for pain control after lung surgery
This trial tests whether putting morphine into the spinal area during lung surgery can reduce pain after surgery for people having certain minimally invasive lung operations. It aims to improve comfort and possibly reduce the need for other pain medicines.
Chicago, IllinoisAges 18–80 - NCT05351801RecruitingPhase 2
Test cannabis-based treatment for nerve pain
This Phase 2 study tests cannabis-derived products to see if they reduce neuropathic (nerve-related) pain in veterans. It may help people whose pain is persistent and causes significant daily impact, especially if certain exam tests show allodynia (pain from normally non-painful touch).
San Diego, CaliforniaAges 21 years+ - NCT05353504Recruiting
Testing how gut changes affect food choices
This study looks at whether interventions that change your gut bacteria can change how you decide what to eat. It may help researchers understand the gut–brain link behind eating behavior.
LeipzigAges 18–60
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Common questions
- Are there clinical trials for placebo?
- Yes. Clin2 currently lists 5,245 recruiting placebo studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a placebo trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a placebo trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.