Clinical trials
Placebo clinical trials
Below are recruiting placebo clinical trials, each written for real people, not researchers. We’re tracking 5,158 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06911359RecruitingPhase 2
Anti-inflammatory vs. Prolotherapy for Knee Osteoarthritis
This study tests whether anti-inflammatory medications or dextrose prolotherapy (sugar water injections) can reduce knee pain and improve function in people with knee osteoarthritis. If you are a military healthcare beneficiary with moderate to severe knee pain, you may be able to join.
Travis AFB, CaliforniaAges 45–75 - NCT06905210RecruitingPhase 3
New hormonal pill for moderate acne in women
This trial tests a new combination hormonal pill (a progestogen and low-dose estrogen) to treat moderate acne in women. It may be an option if you have not had success with other acne treatments.
Itapevi, São PauloAges 14–45 - NCT06901531RecruitingPhase 3
Study of zolbetuximab with pembrolizumab and chemo for gastric cancer
This trial tests a new combination of drugs (zolbetuximab, pembrolizumab, and chemotherapy) for people with advanced stomach or gastroesophageal junction cancer. It may be an option if your tumor has certain proteins (CLDN18.2 and PD-L1) and you haven't had chemotherapy for advanced disease.
Birmingham, AlabamaAges 18 years+ - NCT06902558RecruitingPhase 2
Study of ABBV-CLS-628 for adults with polycystic kidney disease
This trial tests a new drug, ABBV-CLS-628, for people with autosomal dominant polycystic kidney disease (ADPKD). The goal is to see if it slows kidney function decline and is safe to use.
Birmingham, AlabamaAges 18–55 - NCT06910943RecruitingPhase 2/Phase 3
Choline injection for adolescents and adults with intestinal failure on long-term parenteral support
This study tests whether a choline injection can help people with intestinal failure who need long-term intravenous nutrition (parenteral support). It may improve liver health and reduce complications from not getting enough choline through food.
Aurora, ColoradoAges 12 years+ - NCT06905873RecruitingPhase 1
Testing FB102 for non-segmental vitiligo
This study tests a new medicine called FB102 for people with non-segmental vitiligo. It aims to see if the drug is safe and helps restore skin color.
Darlinghurst, New South WalesAges 18–75 - NCT06911112RecruitingPhase 3
A new pill for depression when current treatment isn't working well enough
This trial tests an investigational medication (NBI-1065845) added to your current antidepressant to see if it can improve depressive symptoms. It is for people with moderate to severe depression who have not fully responded to their current antidepressant.
Huntsville, AlabamaAges 18 years+ - NCT06904872RecruitingPhase 2
Testing a diarrhea drug for short bowel syndrome without a colon
This trial tests if crofelemer can reduce diarrhea and fluid loss in people with short bowel syndrome who have a stoma (no colon connection) and need intravenous nutrition or fluids. The goal is to see if it improves gut function and quality of life.
AachenAges 18 years+ - NCT06911424RecruitingPhase 3
Fusidic acid eye drops for bacterial pink eye
This trial tests an antibiotic eye drop called fusidic acid for bacterial conjunctivitis (pink eye). It may help clear the infection if you have had symptoms for less than 48 hours and have not used other eye treatments recently.
Little Rock, ArkansasAges Any age - NCT06901297RecruitingPhase 3
Raphamin for acute sinus infection in adults
This trial tests a new medicine called Raphamin for treating sudden sinus infection (acute rhinosinusitis) in adults. It compares the medicine to a placebo to see if it can reduce symptoms like facial pain and pressure when started within the first 2 days of illness.
AramilAges 18–75 - NCT06904287RecruitingPhase 3
Magnesium for migraine treatment in adults
This trial tests if adding magnesium to a standard migraine medication (prochlorperazine) helps treat migraines more effectively. It could be a good option for adults with migraines who haven't taken these drugs recently.
Oak Lawn, IllinoisAges 18 years+ - NCT06905561Recruiting
Diclofenac cream to prevent skin irritation from radiation
This trial tests if a diclofenac cream can help prevent skin redness, peeling, or pain caused by radiation therapy. It is for people with certain head and neck cancers or breast cancer who are starting radiation treatment.
Haikou, HainanAges 18–75 - NCT06902714RecruitingPhase 3
Tranexamic acid for shoulder replacement recovery
This study tests whether taking an oral medicine called tranexamic acid (TXA) before and after shoulder replacement surgery can reduce bleeding and improve recovery. It is for adults scheduled for a total shoulder replacement who are generally healthy.
Birmingham, AlabamaAges 18–79 - NCT06900972Enrolling by invitationPhase 3
Comparing fluids' effect on heart function
This trial compares two types of IV fluids (colloids and crystalloids) to see how they affect heart function. It is open to healthy adults who are not pregnant and have no known medical problems.
Monastir, TunisiaAges 18–60 - NCT06907329Recruiting
NMN supplement trial for middle-aged adults with metabolic issues
This trial tests whether a sustained-release nicotinamide mononucleotide (NMN) supplement can improve immune aging and metabolism in people aged 50-70 who are overweight or have fatty liver, pre-diabetes, or mild type 2 diabetes.
ShanghaiAges 50–70 - NCT06901739Recruiting
Synbiotic for mental health in obesity
This trial tests if a synbiotic (a mix of probiotics and prebiotics) can improve mental health in people with obesity. It may help if you have obesity and also struggle with anxiety or depression.
Valencia, ValenciaAges 18–65 - NCT06909890Recruiting
Chios mastic water for stomach discomfort
This study tests whether a special water made from Chios mastic can help with dyspepsia (ongoing indigestion or stomach discomfort). It's designed for people who don't have other serious health conditions.
Kallithea, AtticaAges 30–60 - NCT06908473Enrolling by invitationPhase 3
Tongmai Jiangtang capsule for heart risks in metabolic syndrome
This trial tests whether the Tongmai Jiangtang capsule can reduce serious heart and stroke problems in older adults with metabolic syndrome who are also at high risk for heart disease. It focuses on people with a specific traditional Chinese medicine pattern called Qi-deficiency and Blood Stasis.
Guangzhou, GuangdongAges 65 years+ - NCT06905587RecruitingPhase 3
Methylphenidate for fatigue in young brain tumor survivors
This trial tests whether the medicine methylphenidate (often used for ADHD) can help reduce severe fatigue in children and teens who have finished treatment for a brain tumor. If you're a young brain tumor survivor struggling with ongoing tiredness, this study may offer a new option.
AalborgAges 6–27 - NCT06902805RecruitingPhase 2/Phase 3
Testing botox injections and splints for thumb arthritis pain
This study tests if botox injections into the thumb joint, along with a custom splint, can reduce pain from thumb base arthritis. It may be an option if you have persistent pain and have not had recent thumb surgery or certain other treatments.
Paris, Île-de-France RegionAges 18 years+ - NCT06158152Recruiting
AM3 supplement for metabolic syndrome pilot study
This study tests an oral supplement called AM3 in people with metabolic syndrome. It looks at whether the supplement can help improve sugar and fat levels in the blood.
MadridAges 18–75 - NCT06707194RecruitingPhase 4
Penicillin plus etanercept for spondyloarthritis
This trial tests whether adding a common antibiotic (benzathine penicillin) to a standard biologic drug (etanercept) can better treat spondyloarthritis. It may help if you have active disease and are free of certain infections.
Hefei, AnhuiAges 18–59 - NCT06894875Recruiting
Lentil protein's effect on blood pressure and exercise
This trial tests a lentil protein supplement to see if it helps control blood pressure, improve blood vessel function, and boost exercise performance. You may be able to join if you're a healthy, active adult aged 18-45.
Melbourne, VictoriaAges 18–45 - NCT06891365RecruitingPhase 1
Multiple doses of a new drug for fatty liver disease
This trial tests a new medication for people with fatty liver disease. It will see if the drug can reduce liver fat and improve liver health over several doses.
HarrowAges 18–64
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Common questions
- Are there clinical trials for placebo?
- Yes. Clin2 currently lists 5,158 recruiting placebo studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a placebo trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a placebo trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.