Clinical trials
Polycystic Kidney Disease clinical trials
Below are recruiting polycystic kidney disease clinical trials, each written for real people, not researchers. We’re tracking 73 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07454174Recruiting
Study of a dietary program for polycystic kidney disease
This study tests a special medical food (Ren-Nu) to see if it helps with metabolism and kidney health in people with ADPKD. You would follow a dietary program and attend online classes.
Cleveland, OhioAges 18 years+ - NCT07535385Recruiting
Kidney Artery Blocking Treatment for Polycystic Kidney Disease
This study follows patients with a genetic kidney disease (autosomal dominant polycystic kidney disease) who are on dialysis and receive a procedure to block blood flow to their enlarged kidneys. Researchers will track how well the procedure works and how it affects patients over time using imaging scans.
Pavia, LombardyAges 18–75 - NCT06841224Enrolling by invitation
Pressure inside the belly during PD for polycystic kidney disease
This study looks at factors that affect the pressure inside the belly (intraperitoneal pressure) in people with polycystic kidney disease who are on peritoneal dialysis. The goal is to better understand how PD works for these patients and help guide their care.
Beijing, Beijing MunicipalityAges 18–80 - NCT05870007Enrolling by invitationPhase 2
Atorvastatin and alkalizing treatment for autosomal dominant PKD
This Phase 2 study tests whether atorvastatin plus an “alkalizing” treatment (sodium bicarbonate) can slow or improve disease effects in people with autosomal dominant polycystic kidney disease (ADPKD). It specifically targets metabolic acidosis (when the body becomes “too acidic”), which may worsen kidney health.
New Taipei CityAges 18 years+ - NCT03901521Enrolling by invitation
Biobank for people with autosomal dominant polycystic kidney disease
This study collects samples and health information from adults with autosomal dominant polycystic kidney disease (ADPKD) who are having their own kidney removed. It helps researchers learn more about ADPKD and its genetic changes to support future treatments.
New York, New YorkAges 18–100 - NCT07419828RecruitingPhase 3
Study of HRS-1780 for chronic kidney disease
This trial tests an investigational drug called HRS-1780 in people with chronic kidney disease. It aims to see if the drug can help slow kidney decline and is safe to use.
Nanjing, JiangsuAges 18–80 - NCT05732727RecruitingPhase 3
Stronger BP lowering using diuretics in kidney disease
This Phase 3 trial compares a plan that uses diuretics (water pills) to lower blood pressure more, versus usual blood pressure care, in people with uncontrolled hypertension and moderate-to-severe chronic kidney disease. It may help your blood pressure control while monitoring safety closely because kidney function changes how medicines work.
AngersAges 18 years+ - NCT05970172RecruitingPhase 3
Roxadustat for anemia in kids with chronic kidney disease
This study tests roxadustat, a medicine that helps the body make more red blood cells, in children and teens with anemia caused by chronic kidney disease. It may help improve anemia and related blood counts, while also monitoring safety.
BrusselsAges 2–17 - NCT06202235Recruiting
Magnetic resonance imaging for chronic kidney disease
This trial uses a special MRI technique called multifrequency magnetic resonance elastography (MRE) to see if it can help evaluate chronic kidney disease. It may provide a non-invasive way to monitor kidney health without needing a biopsy.
Shenyang, LiaoningAges 18–65 - NCT06256991RecruitingPhase 4
Potassium management for kidney health
This study tests if careful potassium management can help people with chronic kidney disease (CKD) safely take higher doses of blood pressure medicines called ACE inhibitors or ARBs, which are known to protect the kidneys. You may be eligible if you have moderate to advanced CKD and are already on a moderate dose of one of these medications.
GroningenAges 18 years+ - NCT06322056Recruiting
Lower blood pressure and cholesterol targets for advanced kidney disease
This trial tests whether keeping blood pressure and cholesterol at lower-than-usual levels can help slow the decline of kidney function in people with advanced chronic kidney disease. If you have moderately to severely reduced kidney function and meet certain blood pressure and cholesterol criteria, you may be able to join.
SeoulAges 19 years+ - NCT07239570RecruitingPhase 4
Using biomarkers to personalize kidney disease treatment
This study tests if matching treatments to your specific kidney disease markers can better protect your kidneys. It looks at how well Finerenone, Dapagliflozin, and Semaglutide work alone or in a sequence.
HerlevAges 18–75 - NCT02848131Enrolling by invitationPhase 2
Testing dasatinib and quercetin in diabetes-related kidney disease
This study tests whether two medicines (dasatinib and quercetin) can affect “cell aging” in people with chronic kidney disease related to diabetes. You may be asked to take pills for a short period and complete follow-up visits to measure how your body responds.
Jacksonville, FloridaAges 40–80 - NCT07405216RecruitingPhase 4
SGLT2 inhibitors for teens with early kidney disease
This trial tests whether a type of medicine called SGLT2 inhibitors can help teenagers with early-stage chronic kidney disease. It looks at how safe and effective these drugs are for slowing down kidney damage.
Aguascalientes, AguascalientesAges 14–18 - NCT06600412RecruitingPhase 2
Testing R3R01 for protein in urine from diabetic kidney disease
This trial tests if a new drug, R3R01, can help reduce protein leaking into the urine in people with diabetic kidney disease. It may offer a new option for managing kidney health.
Copenhagen, CopenhagenAges 18 years+ - NCT06824987RecruitingPhase 2
Study of AZD2373 for APOL1-related kidney disease
This trial tests an experimental drug (AZD2373) for people with kidney disease caused by APOL1 gene changes. It aims to find the safest and most effective dose to slow kidney damage.
Alabaster, AlabamaAges 18–65 - NCT06147414Recruiting
Blood test for genetic disorders in pregnancy
This study tests a safer blood test to check for certain genetic disorders during pregnancy, instead of an invasive procedure like amniocentesis. It's for pregnant women who are at risk of passing on a known genetic condition.
ParisAges 18 years+ - NCT04111692Recruiting
Watching foam treatment for cysts in autosomal polycystic disease
This study follows adults with inherited kidney and/or liver cysts that are causing symptoms to see how a foam sclerotherapy procedure may help and what outcomes happen over about a year. You may be eligible if you have a few sizable, specific-type cysts and can safely attend follow-up visits.
Rochester, MinnesotaAges 18–100 - NCT07745920Recruiting
An online program for depression in people with adpkd
This study tests an internet-based program to help manage depression symptoms in people with ADPKD. The program may be a convenient way to get support for your mood without traveling to a clinic.
Rochester, MinnesotaAges 18–70 - NCT06714006RecruitingPhase 1
Testing safety of PYC-003 for ADPKD
This study is testing a new investigational medicine called PYC-003 for people with autosomal dominant polycystic kidney disease (ADPKD). It is one of the first studies in humans, so the main goal is to see if the medicine is safe and tolerable. The study is for people with a specific genetic cause (PKD1 mutation) and with certain kidney imaging types.
Southport, Gold CoastAges 18–65 - NCT04039061Recruiting
Study registry for people with ADPKD
This trial is a patient registry that collects information from people who have—or might have—autosomal dominant polycystic kidney disease (ADPKD). It may help researchers better understand the condition and improve future studies.
Kansas City, MissouriAges Any age - NCT04338048Recruiting
Study for autosomal dominant polycystic kidney disease
This study enrolls people who have been diagnosed with autosomal dominant polycystic kidney disease (ADPKD), a genetic kidney condition that can cause kidney cysts. It aims to learn about this specific form of the disease so better care is possible for the right patients.
Washington D.C., District of ColumbiaAges Up to 18 years - NCT04630613Recruiting
Studying NOX4 markers in young adults with ADPKD
This study measures a kidney-related marker (NOX4) and other blood/urine signals in people with early-stage ADPKD to better understand disease activity. It may help researchers identify who is likely to progress and why, though it may not be a treatment study.
Rochester, MinnesotaAges 15–40 - NCT05373264RecruitingPhase 3
Hydrochlorothiazide to help polycystic kidney disease and quality of life
This Phase 3 study tests whether hydrochlorothiazide can help people with autosomal dominant polycystic kidney disease (ADPKD) and improve quality of life. It also looks at whether it affects kidney health while you stay on your current ADPKD-related treatment.
BrusselsAges 18–80
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Common questions
- Are there clinical trials for polycystic kidney disease?
- Yes. Clin2 currently lists 73 recruiting polycystic kidney disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a polycystic kidney disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a polycystic kidney disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.