Clinical trials
PTSD clinical trials
Below are recruiting ptsd clinical trials, each written for real people, not researchers. We’re tracking 296 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05776056RecruitingPhase 4
Methylphenidate for PTSD with memory and thinking problems
This study tests whether methylphenidate, a medication commonly used for attention issues, can help veterans with PTSD who also have memory or concentration problems. The goal is to see if it improves these cognitive symptoms.
Birmingham, AlabamaAges 18–65 - NCT05746572Enrolling by invitationPhase 2
MDMA-assisted therapy plus exposure therapy for PTSD
This Phase 2 study tests whether MDMA combined with therapy that uses exposure (gradual confronting of trauma memories) can reduce PTSD symptoms. It may help people who meet PTSD criteria, can follow strict safety rules, and can complete medicine-session monitoring.
Atlanta, GeorgiaAges 21–70 - NCT05758987Recruiting
Online therapy for PTSD using a computer program
This trial studies a new blended, computer-assisted version of trauma-focused cognitive behavioral therapy for people with PTSD. It may help reduce PTSD symptoms by delivering structured therapy using a computer and online sessions.
StockholmAges 18 years+ - NCT05674617Recruiting
PTSD treatment for Veterans with serious mental illness
This trial tests a PTSD treatment approach for Veterans who also have a serious mental illness, aiming to improve day-to-day functioning. It includes Veterans who receive outpatient mental health care through the VA and have confirmed PTSD in the last month.
Baltimore, MarylandAges 18 years+ - NCT05423444Recruiting
Therapy for PTSD in teens using brain connectivity imaging
This study looks at how well PTSD-focused therapy changes brain “connectivity” patterns in adolescents. It may help your care team understand which teens benefit most from therapy.
San Antonio, TexasAges 12–17 - NCT05457985Recruiting
Adaptive app coaching for PTSD in community health clinics
This study tests a flexible (adaptive) approach using a mobile app to help improve treatment outcomes for posttraumatic stress disorder (PTSD) for people getting care at participating community health clinics. It may help you get more tailored support between visits.
Baldwin, MichiganAges 18 years+ - NCT05267665Recruiting
Family-involved PTSD therapy coaching for Veterans
This study tests a brief way to include a Veteran’s family member to improve PTSD treatment results and help people stay engaged in care. It’s for Veterans who are just starting evidence-based PTSD therapy and have a closely involved family member who can participate too.
Boston, MassachusettsAges 18 years+ - NCT05269459RecruitingPhase 2
Cannabidiol (CBD) for PTSD symptoms in adults
This study tests whether CBD, a non-psychoactive compound from cannabis, can help reduce symptoms of post-traumatic stress disorder (PTSD) in adults. If you have PTSD and are interested in a non-traditional treatment option, this might be worth exploring.
Omaha, NebraskaAges 21–65 - NCT05194930Recruiting
Insomnia treatment study for Veterans with PTSD symptoms
This study tests treatments to help Veterans who have both PTSD symptoms and trouble sleeping (insomnia). You may be invited to try study procedures to see what helps insomnia and whether it also improves sleep-related well-being.
Sepulveda, CaliforniaAges 18 years+ - NCT04877093RecruitingPhase 3
Low-dose clonidine for PTSD nightmares in veterans
This Phase 3 study tests whether low-dose clonidine can reduce PTSD symptoms and especially nightmares in U.S. veterans. You’d be screened for PTSD severity and current treatments, then asked to visit the clinic as scheduled to see if the treatment helps.
Wauwatosa, WisconsinAges 18 years+ - NCT04550377RecruitingPhase 2
Cannabidiol for PTSD, including PTSD after mild head injury
This Phase 2 study tests whether cannabidiol (CBD) can reduce PTSD symptoms, including in people who also had a mild traumatic brain injury (TBI). It’s meant to see if CBD is helpful and safe for PTSD symptoms over the study period.
New York, New YorkAges 18–70 - NCT04452500RecruitingPhase 2
Study drug for PTSD symptoms in Veterans
This trial tests a study medicine that blocks the effects of cortisol (a stress hormone) to reduce PTSD symptoms in Veterans. It’s meant for people with ongoing PTSD symptoms and stable treatments, and it closely checks safety because the medicine can affect sleep, mood, and heart rhythm.
Tuscaloosa, AlabamaAges 18–69 - NCT04335487Recruiting
Online therapy program for PTSD symptoms in public safety workers
This study tests an internet-based cognitive-behavioral therapy (an online talk-therapy style program that helps you manage thoughts and feelings) to reduce PTSD symptoms in public safety personnel. You may be able to join if you have PTSD-like symptoms and can safely take part in online treatment.
Regina, SaskatchewanAges 18 years+ - NCT03803332Recruiting
Therapies for PTSD from military sexual trauma compared for adults
This trial compares two types of talk therapy to treat PTSD caused by military sexual trauma. It aims to see which therapy helps symptoms better and how well people can complete weekly outpatient sessions.
New York, New YorkAges 18–85 - NCT05732155RecruitingPhase 2
MDMA-assisted therapy for war-related PTSD
This study tests whether combining MDMA with talk therapy can help people with post-traumatic stress disorder (PTSD) from war experiences. It involves both individual and group therapy sessions, and the medication is given during some sessions.
AfulaAges 18 years+ - NCT05233111Enrolling by invitation
Exposure therapy to reduce PTSD after spinal cord injury
This trial compares a specific type of talk therapy (brief prolonged exposure) versus standard care to reduce post-traumatic stress symptoms after a spinal cord injury. If you qualify, you may get extra support targeted at PTSD symptoms during inpatient rehab.
Dallas, TexasAges 18 years+ - NCT07767396Recruiting
Eye movement technique for reducing intrusive trauma memories
This study tests whether a specific eye movement technique, done at home on a computer, can help reduce distressing, intrusive memories after trauma. If you've been having frequent, unwanted trauma memories, this could help you gain better control over them.
Xi'an, ShaanxiAges 18–50 - NCT04512755Recruiting
AIMS medical outcomes study for new or established patients
This is an observational study where the AIMS team collects information from patients during a first visit or ongoing care. It helps the clinic understand patients’ experiences and outcomes, but it does not test a new medicine.
Seattle, WashingtonAges Any age - NCT04985344RecruitingPhase 3
Propranolol to treat PTSD symptoms in children using memory reactivation
This trial studies whether propranolol (a heart-related medicine) can help children with post-traumatic stress disorder (PTSD) after a special memory-activation session. The goal is to reduce PTSD symptoms compared with the comparison condition.
ToulouseAges 7–12 - NCT06279598Recruiting
Predicting PTSD treatment success and handling non-response (PT-STRESS)
This study looks at how well PTSD treatments work and what happens when they don't. It tests ways to predict if a treatment will be successful for you.
DeventerAges 18–65 - NCT06185244Recruiting
Online trauma therapy for teens with PTSD
This study tests an online therapy for teenagers with PTSD. It's a type of talk therapy that helps you deal with trauma, and you and your parent take part from home.
StockholmAges 13–17 - NCT05646732Recruiting
Brain scan and stimulation study for PTSD in adults
This study uses MRI brain scans and a noninvasive brain stimulation (TMS) to better understand PTSD in the brain. It may help researchers identify brain patterns linked to PTSD and how brain stimulation affects them.
Palo Alto, CaliforniaAges 18–55 - NCT06363968Recruiting
Eye tests to predict PTSD treatment response in veterans
This study looks at whether certain eye tests can help predict how well PTSD treatments work. It's for veterans with PTSD who are not taking certain medications and have no serious eye or health conditions.
Seattle, WashingtonAges 21–75 - NCT07852728RecruitingPhase 2
Oxygen therapy for first responders after head injuries
This trial tests whether hyperbaric oxygen therapy (breathing pure oxygen in a pressurized chamber) can improve thinking, mood, and overall well-being in first responders who have had a traumatic brain injury and still have symptoms. If you are a first responder dealing with ongoing brain injury symptoms, this study could help you find new ways to feel better.
Boise, IdahoAges 18–75
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Common questions
- Are there clinical trials for ptsd?
- Yes. Clin2 currently lists 296 recruiting ptsd studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a ptsd trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a ptsd trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.