Clinical trials
Postoperative Adjuvant Treatment clinical trials
Below are recruiting postoperative adjuvant treatment clinical trials, each written for real people, not researchers. We’re tracking 55 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07266480RecruitingPhase 2
Adalimumab after surgery for esophageal cancer
This trial tests whether adding adalimumab (a medicine that helps the immune system) after surgery can prevent esophageal cancer from coming back. It's for people who have already had their cancer completely removed by surgery.
Shijiazhuang, HebeiAges 18 years+ - NCT06774222RecruitingPhase 2
Fruquintinib plus chemo for HER2-negative gastric cancer
This trial tests adding fruquintinib (a targeted drug that blocks blood vessel growth) to chemotherapy after surgery for HER2-negative stomach or gastroesophageal junction cancer. It is for patients whose tumor did not respond well to previous treatment before surgery.
ZhengzhouAges 18–75 - NCT06685289RecruitingPhase 2
Donafenib and capecitabine after surgery for biliary cancer with high risk of return
This trial tests whether taking donafenib and capecitabine pills after surgery can help prevent biliary cancer from coming back in people who have a high risk of recurrence. It is for patients whose cancer was completely removed but had certain features that make recurrence more likely.
Nanjing, JiangsuAges 18–75 - NCT04120701RecruitingPhase 3
Using blood DNA tests to guide colon cancer treatment after surgery
This trial tests whether a blood test that looks at cancer DNA can help decide whether you need “adjuvant” (extra) chemotherapy after colon cancer surgery. It may help some patients avoid unnecessary chemotherapy while still keeping the cancer from coming back.
DijonAges 18–75 - NCT07034742RecruitingEarly Phase 1
MRD testing after stomach cancer surgery
This study looks at whether a blood test for leftover cancer cells (called MRD) after stomach cancer surgery can help guide treatment. It is for people with a certain type of stomach cancer that has spread to nearby tissues but not to distant organs, and who are having surgery as their first treatment.
BeijingAges 18–75 - NCT04790305RecruitingPhase 4
Huaier granules with standard therapy for early triple-negative breast cancer
This trial looks at whether adding Huaier granules to usual after-surgery treatment can improve outcomes for people with high-risk early-stage triple-negative breast cancer. It focuses on whether the added supplement is safe and helpful after standard care.
Hefei, AnhuiAges 18–70 - NCT05420467RecruitingPhase 4
Trial of add-on breast cancer treatment after surgery
This Phase 4 study tests an additional (adjuvant) treatment for breast cancer after surgery and standard follow-up care. It may help lower the chance the cancer comes back, but you must match specific tumor and body-chemistry requirements to join.
Hangzhou, ZhejiangAges 18 years+ - NCT05430698RecruitingPhase 2
PD-1 antibody after surgery for bile duct cancer
This Phase 2 trial studies whether adding a PD-1 antibody plus gemcitabine/oxaliplatin (GEMOX) after surgery can lower the chance of the cancer coming back in perihilar cholangiocarcinoma. It’s for people who have had surgery with no tumor left at the cut edges, but lymph nodes showed cancer under the microscope.
Guangzhou, GuangdongAges 18–75 - NCT05927584Recruiting
Local removal for early rectal cancer without extra treatment
This trial studies removing an early rectal cancer tumor locally (through the rectum/anal area) with no additional therapy afterward. The goal is to preserve organs and maintain quality of life while still trying to cure the cancer.
MadridAges 18 years+ - NCT06109454Recruiting
Huaier granules after lung cancer surgery
This study tests whether Huaier granules can help prevent lung cancer from coming back after surgery. It is for people with stage II–IIIA non-small cell lung cancer who have recently had their tumor completely removed and have not had other treatments like chemotherapy or radiation.
Shenyang, LiaoningAges 18–75 - NCT06306612Recruiting
Surgery plus hormone therapy for advanced prostate cancer
This trial tests whether removing the prostate (surgery) plus standard hormone therapy and chemotherapy can help men whose prostate cancer has spread to many places in the body. It is for men who have not yet had treatment for their cancer.
Shanghai, Shanghai MunicipalityAges 18–85 - NCT06402708RecruitingPhase 3
Chemotherapy after surgery for thymic cancer
This trial tests whether additional chemotherapy after surgery can help prevent thymic cancer from coming back. It is for people who have had their thymus tumor completely removed and are in good health.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06498622RecruitingPhase 2
Liver cancer relapse prevention after surgery
This trial tests a combination of two drugs (Donafenib and Envafolimab) after surgery to lower the risk of liver cancer coming back in people who have high-risk features. It may help if you qualify based on your tumor(s) and overall health.
Fuyang, AnhuiAges 18–80 - NCT06826885Recruiting
Comparing two types of radiation for breast cancer
This trial is testing how well two different radiation techniques, IMPT and IMRT, work for treating breast cancer. It aims to see which one is safer and more effective, so you might benefit from a potentially better treatment approach.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07037576Recruiting
Breast reconstruction study for patients needing radiation after mastectomy
This study compares two types of breast reconstruction for women who need radiation therapy after their mastectomy: one-stage reconstruction using a permanent implant placed in front of the chest muscle, versus the standard two-stage approach where a tissue expander is used first and replaced with a permanent implant later. The goal is to see which method works better and is safer for patients who require post-mastectomy radiation.
Henan, HenanAges 18–70 - NCT07156058Recruiting
Personalized therapy after surgery for bile duct cancer
This trial uses a test called MiniPDX, which grows a tiny sample of your tumor in mice to see which drugs work best. After your surgery, you'll receive chemotherapy chosen specifically for your cancer to help prevent it from coming back.
BeijingAges 18 years+ - NCT07331883RecruitingPhase 2
Sintilimab and bevacizumab after surgery for ruptured liver cancer
This trial tests whether combining two immune-based drugs (sintilimab and a bevacizumab biosimilar) after surgery can prevent liver cancer from returning in people whose tumor had ruptured. It’s for patients who have had a complete surgical removal of a ruptured hepatocellular carcinoma and are now cancer-free on imaging.
Sanming, FujianAges 18–75 - NCT07337421RecruitingPhase 2
Chemo infusion after liver cancer surgery to lower recurrence risk
This trial tests whether a targeted chemotherapy infusion directly into the liver's main artery (HAIC) after surgery can prevent liver cancer from coming back. It is for people with certain high-risk features, like a large tumor or cancer in blood vessels, who have had their tumor completely removed.
Yangzhou, JiangsuAges 18–75 - NCT07379255Recruiting
Organoid test to guide chemo after bladder cancer surgery
This trial uses a lab-grown version of your tumor (an organoid) to see which chemotherapy might work best for you after bladder cancer surgery. It helps doctors choose the most effective treatment for each person.
Jinan, ShandongAges 18–80 - NCT07495215RecruitingPhase 1/Phase 2
Personalized mRNA vaccine plus immunotherapy for liver cancer after surgery
This trial tests a personalized mRNA vaccine (iNeo-Vac-R01) combined with a PD-1 inhibitor to prevent liver cancer from coming back after surgery. It is for people with early-stage liver cancer who have a high risk of recurrence.
Hangzhou, ZhejiangAges 18–75 - NCT06496373RecruitingEarly Phase 1
mRNA vaccine plus immunotherapy after pancreatic cancer surgery
This trial tests a personalized mRNA vaccine combined with an immunotherapy drug (PD-1 inhibitor) to prevent pancreatic cancer from returning after surgery. It is for patients whose tumors have specific genetic features and who cannot have standard chemotherapy.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07296250Recruiting
Tracking cancer cells after chemoradiation for oral cancer
This trial studies whether detecting circulating tumor cells in the blood after chemoradiation can help predict outcomes for people with oral cancer that has spread to lymph nodes. It may help doctors better monitor the disease.
Taoyuan CityAges 1.5 years–90 years - NCT07063888RecruitingPhase 2
Chemoradiation after surgery for bile duct cancer
This trial tests whether combining chemotherapy with radiation after surgery can help prevent the return of intrahepatic cholangiocarcinoma, a type of bile duct cancer. It is for people whose surgery showed a narrow margin or cancer in nearby lymph nodes.
BeijingAges 18–80 - NCT07116213Recruiting
Shorter radiation after surgery for high-risk endometrial cancer
This trial studies a new type of radiation therapy (called online adaptive radiotherapy) given in shorter, higher daily doses after surgery for high-risk endometrial cancer. The goal is to see if this approach is safe and effective for reducing side effects while still controlling the cancer.
Beijing, Beijing MunicipalityAges 18–70
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Common questions
- Are there clinical trials for postoperative adjuvant treatment?
- Yes. Clin2 currently lists 55 recruiting postoperative adjuvant treatment studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a postoperative adjuvant treatment trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a postoperative adjuvant treatment trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.