Clinical trials
Postoperative Analgesia clinical trials
Below are recruiting postoperative analgesia clinical trials, each written for real people, not researchers. We’re tracking 175 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06600815Recruiting
Step-by-step numbing shots for pain relief in knee replacement
This study tests whether a special step-by-step numbing injection given before knee replacement surgery can provide better pain relief during and after the procedure. It may help you have less pain and use fewer painkillers after surgery.
Fuzhou, FujianAges 18 years+ - NCT07239817Recruiting
Nerve block plus numbing medicine for hip fracture surgery
This study tests a special nerve block (PENG block) combined with a numbing medicine injection around the hip joint to provide better pain relief after hip replacement surgery for a broken hip. It aims to see if this approach can reduce pain and the need for strong pain medicines.
MilanAges 18 years+ - NCT06075004Recruiting
Hip pain relief study comparing two injection methods
This trial tests two ways to give pain medicine around the hip joint during surgery to see which provides better pain relief. It may help patients experience less pain after hip replacement.
Santiago, Santiago MetropolitanAges 18–80 - NCT07337629Recruiting
Painkiller Before Nose Surgery: Paracetamol vs. Ibuprofen
This study tests whether giving a single dose of paracetamol or ibuprofen before nose surgery can reduce the need for stronger painkillers during and after the procedure. It may help you recover with less opioid pain medicine.
SamsunAges 18 years+ - NCT07334288Recruiting
Numbing injection for pain relief after lower back surgery
This study tests a numbing injection near the spine (retrolaminar block) to reduce pain after lower back surgery with hardware. It could help you use less pain medicine and recover more comfortably.
Santiago, Santiago MetropolitanAges 18–80 - NCT05893030Recruiting
Monitoring pain and sleep medicines to prevent complications after surgery
This study looks at whether closely monitoring opioid and sleep medicines during and after surgery can lower organ problems and death in older adults at high risk. If you qualify, your team will track how these medicines are given to help keep you safer in the postoperative period.
AmiensAges 75 years+ - NCT07770932Recruiting
Pain relief after hip replacement surgery
This study compares two types of nerve blocks for pain relief after hip replacement surgery. It aims to find which method reduces pain and improves recovery.
Istanbul, BagcilarAges 18–80 - NCT07587203Enrolling by invitation
Numbing medication for shoulder surgery and breathing
This trial compares two types of numbing medications (liposomal bupivacaine and standard bupivacaine) given as a nerve block for shoulder surgery. Researchers want to see which one works better for pain relief and causes fewer problems with your breathing afterward.
Nanjing, JiangsuAges 18–80 - NCT07716566Recruiting
Nerve block for pain after kidney transplant
This trial tests a nerve block called a quadroiliac plane block to see if it helps control pain after kidney transplant surgery. If you are having a kidney transplant, this study might help reduce your pain and need for pain medication.
Istanbul, IstanbulAges 18–80 - NCT06586840Recruiting
Adding an extra nerve block to knee replacement
This trial tests if adding a special nerve block behind the knee (IPACK) to a standard thigh block helps control pain better after total knee replacement. It may lead to less pain and faster recovery.
AydinAges 18–85 - NCT06887153Recruiting
Pain medicine use after major surgery
This study looks at how different pain medicines are used together after major surgery and how well they control pain. It may help improve pain relief for people having planned bone, belly, or chest surgeries.
KampalaAges 18 years+ - NCT07271849RecruitingPhase 4
Timing of Nalbuphine for Pain and Blood Pressure in Older Knee Surgery Patients
This study tests whether giving the pain medicine nalbuphine at different times during knee replacement surgery affects blood pressure and pain control in older adults. It may help find the best timing to reduce pain and keep vital signs stable.
Jinan, ShandongAges 65–90 - NCT07525986RecruitingPhase 4
Pain control after laparoscopic colon surgery using a button-press system
This trial tests a new pain medication (anrikefon) that patients can control themselves by pressing a button after laparoscopic colon surgery. The goal is to see if it works better or safer than standard pain relief, especially for patients whose nerve blocks alone don't fully control pain.
Beijing, Beijing MunicipalityAges 18–75 - NCT05672784Recruiting
Knee numbing injections during knee replacement surgery
This trial compares two ways of numbing a knee area during planned knee replacement surgery: a nerve block alone versus a nerve block plus additional numbing medicine near the back of the knee. It may help doctors find which approach improves pain control and recovery while keeping side effects low.
ZagazigAges 21–60 - NCT05543785Recruiting
Ketorolac pain block for lower-limb surgery with a tourniquet
This trial looks at whether a ketorolac pain medicine given directly to the leg during surgery can reduce pain after lower-limb orthopedic operations. It may help people who are having one leg operated on with spinal anesthesia and a tourniquet, but it has several safety limits.
Al MansurahAges 19–60 - NCT06276257Recruiting
Pain block for mastectomy with immediate reconstruction
This trial tests a nerve block to reduce pain after breast removal surgery with immediate reconstruction. It may help you recover with less discomfort.
Québec, QuebecAges 18–70 - NCT07394673Recruiting
Nerve block for pain after shoulder surgery
This trial tests a new ultrasound-guided nerve block for pain relief after shoulder surgery. It aims to improve comfort and reduce the need for pain medications.
BursaAges 18–65 - NCT07561333Recruiting
Pain Relief Methods for Knee Replacement Surgery
This study compares two different nerve-blocking anesthesia techniques to see which one controls pain better after knee replacement surgery. Both methods are designed to numb the area around your knee so you need less pain medication afterward.
Çorum, CentreAges 18–80 - NCT06976320Recruiting
Nerve block for gallbladder surgery pain
This trial tests a nerve block injection in the abdominal wall to reduce pain after gallbladder removal surgery. It may help patients recover more comfortably.
IstanbulAges 18–80 - NCT07709975Recruiting
Pain relief and early movement for older ICU patients
This study tests different ways to manage pain and help older patients get moving again sooner after major surgery. If you are 65 or older and in the ICU, this trial may help you recover more comfortably and quickly.
Istanbul, IstanbulAges 65 years+ - NCT03715517Recruiting
Spinal anesthesia to improve recovery after liver surgery
This trial studies whether using spinal/epidural anesthesia during liver tumor removal surgery can help people recover better and with less pain. It compares this approach to standard general anesthesia care to see if recovery is smoother.
Winnipeg, ManitobaAges 18 years+ - NCT06205355Recruiting
Pain measurement tool for jaw surgery patients
This study tests a device that measures your body's response to pain during jaw surgery. It may help doctors better manage your pain during and after the procedure.
SeoulAges 18 years+ - NCT07411521Recruiting
Comparing two pain relief methods after planned cesarean
This trial compares two ways to manage pain after a planned cesarean section: one combines a spinal and epidural injection, the other is a newer type of nerve block. The goal is to see which provides better pain relief with fewer side effects.
Bursa, NilüferAges 18–45 - NCT06186141RecruitingPhase 4
Comparing morphine and oxycodone for kids' pain after surgery
This study compares two common pain medicines—morphine and oxycodone—given through a PCA pump after surgery in children. The goal is to see which one causes less nausea and vomiting, so your child can recover more comfortably.
Melbourne, VictoriaAges 6–18
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Common questions
- Are there clinical trials for postoperative analgesia?
- Yes. Clin2 currently lists 175 recruiting postoperative analgesia studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a postoperative analgesia trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a postoperative analgesia trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.