Clinical trials
Postoperative Delirium clinical trials
Below are recruiting postoperative delirium clinical trials, each written for real people, not researchers. We’re tracking 95 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06522087Recruiting
40 Hz brain stimulation to prevent confusion after hip or knee replacement
This trial tests if a non-invasive 40 Hz brain stimulation can prevent delirium (sudden confusion) in older adults after hip or knee replacement surgery. Delirium is common after surgery in elderly patients, and this treatment aims to lower that risk.
Zhengzhou, HenanAges 65–85 - NCT05242419Recruiting
Huperzine A to reduce confusion after non-heart surgery
This trial studies whether a medicine called huperzine A can reduce “postoperative delirium,” which is sudden confusion after surgery, in older adults. It focuses on people having non-heart surgery under general anesthesia for at least two hours.
Wenzhou, ZhejiangAges 75 years+ - NCT06844279Recruiting
Anesthesia depth monitoring for recovery after spinal surgery in older adults
This study tests whether carefully monitoring how deep your anesthesia is during spinal surgery can help older adults recover better and think more clearly afterward.
AnkaraAges 65 years+ - NCT06510140Recruiting
Brain monitoring and frailty to predict confusion after surgery in older adults
This study tests if monitoring your brain waves during surgery and checking your frailty level can help predict whether you might become confused after surgery. It aims to improve care for older adults having major non-cardiac operations.
Saint-EtienneAges 75 years+ - NCT06938789Recruiting
Bleeding and confusion after hip fracture in older adults
This study looks at how bleeding after a hip fracture might affect confusion (delirium) in older adults. It will help doctors understand how to better manage bleeding to prevent confusion.
Aarhus, Central JutlandAges 75 years+ - NCT06687291Recruiting
Thinking and memory after stomach or esophagus cancer surgery
This study looks at how surgery and chemotherapy for stomach or esophageal cancer may affect your thinking, memory, and other cognitive functions. Researchers want to understand these changes to better support patients.
HuddingeAges 18 years+ - NCT07736092Recruiting
Light Therapy Before and After Surgery for Older Adults
This trial tests a gentle light treatment to help prevent thinking problems after surgery in older patients. It involves using a special light on your head before and after your operation.
Beijing, Beijing MunicipalityAges 65 years+ - NCT06421077Recruiting
Ear nerve stimulation to prevent confusion after surgery in older adults
This trial tests if a gentle electrical stimulation on the ear can help prevent postoperative delirium (sudden confusion) in older patients after surgery. It focuses on people 65 and older who will have longer operations.
BeijingAges 65 years+ - NCT04792554Recruiting
Study of aging around major non-heart surgery
This study looks at changes in health and function in older adults before and after major surgery. It may help doctors understand how “aging” affects recovery and what could improve outcomes.
SingaporeAges 65–100 - NCT05514405Recruiting
Testing two anesthesia medicines to prevent confusion after surgery
This trial tests whether using remimazolam or propofol during hip or knee replacement surgery can lower the risk of postoperative delirium, a sudden, short-term confusion that can happen after anesthesia. It may help people who are at higher risk of postoperative confusion by finding the safer anesthesia approach.
SeoulAges 65–100 - NCT05993754Recruiting
Preventing confusion after surgery in frail older adults
This study tests whether a special nursing care plan can help prevent confusion after surgery in older adults who are frail. If you are 65 or older, having planned surgery, and generally healthy enough, this trial may be an option.
Santiago, Santiago MetropolitanAges 65 years+ - NCT06138340Recruiting
How anesthesia affects brain networks in people with glioma
This study looks at how different anesthetics change brain connections during surgery for a type of brain tumor called glioma. It may help doctors choose the best anesthesia for your surgery.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06426953Recruiting
Proteins in blood to predict confusion after surgery in older diabetics
This study looks at proteins in your blood (TGF-β and INS-PI3K-AKT) to see if they can predict confusion after surgery (postoperative delirium) in older adults with diabetes. It may help doctors identify who is at higher risk.
Duyun, GuizhouAges 65 years+ - NCT06631534RecruitingPhase 4
Testing dexmedetomidine for kids having heart defect closure
This trial tests adding a sedative medicine called dexmedetomidine to standard anesthesia for children aged 3 to 12 who are having a procedure to close a hole in their heart (atrial septal defect). The goal is to see if it helps them recover more smoothly.
Alexandria, Alexandria GovernorateAges 3–12 - NCT07059585Recruiting
Preoperative assessment for older adults and delirium risk
This study looks at whether a comprehensive check-up before surgery can help predict or prevent confusion after surgery in older adults. It focuses on people who are considered frail and are having planned inpatient surgery with general anesthesia.
Miami, FloridaAges 60 years+ - NCT07627906RecruitingPhase 3
Comparing Two Sedatives to Prevent Confusion After Cancer Surgery
This study tests two different sedative medications (ketofol and ketodex) to see which one better prevents postoperative delirium—a type of confusion that can happen after surgery—in older adults undergoing cancer surgery. The goal is to find the safest, most effective option for elderly patients.
Cairo, Cairo GovernorateAges 60 years+ - NCT07488468Recruiting
Shortening fasting before planned surgery
This trial tests a program to reduce how long patients must fast before elective surgery. Shorter fasting may make patients more comfortable and could help recovery.
GiessenAges Any age - NCT07714785Recruiting
EEG-guided anesthesia for better recovery after tonsillectomy
This study tests whether using brain-wave monitoring (EEG) during anesthesia with sevoflurane can reduce the amount of pain medicine needed after tonsillectomy and improve how smoothly children wake up. It could help your child have a more comfortable recovery.
Santiago, RegiónAges 2–8 - NCT05541276RecruitingPhase 3
Melatonin to prevent waking confusion in young children after surgery
This study tests whether giving melatonin before surgery can help prevent agitation and confusion in young children after they wake up from anesthesia. Participation may help your child have a smoother recovery after their procedure.
Copenhagen, Capital RegionAges 1–6 - NCT07408037Recruiting
Child breathing game before surgery for anxiety and delirium
This trial tests if a fun breathing exercise before surgery can help reduce anxiety and confusion in young children. Your child may be eligible if they are 3-7 years old and having planned surgery.
Bursa, BursaAges 3–7 - NCT07534956Recruiting
Anesthesia Methods and Waking Up Agitation in Children
This study compares different anesthesia approaches to see which one helps children wake up more calmly after urogenital surgery (surgery on the urinary or reproductive system). Researchers want to find the best way to reduce agitation and confusion as children wake up from anesthesia.
IstanbulAges 3–10 - NCT07295184Recruiting
Rebound pain and confusion after hip surgery
This study looks at a way to reduce confusion after hip surgery. If you are having planned hip surgery and get a nerve block for pain, researchers will check if rebound pain affects your recovery in the hospital.
Konya, KaratayAges 18–80 - NCT07435675Recruiting
Nerve block to prevent agitation after ear surgery in children
This study tests if a nerve block behind the ear can help children ages 5–14 stay calm and comfortable after middle ear surgery. It may reduce confusion and restlessness when waking up from anesthesia.
Al Fayyum, Faiyum GovernorateAges 5–14
Hear when a new Postoperative Delirium trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for postoperative delirium?
- Yes. Clin2 currently lists 95 recruiting postoperative delirium studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a postoperative delirium trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a postoperative delirium trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.