Clinical trials
Postoperative Pain clinical trials
Below are recruiting postoperative pain clinical trials, each written for real people, not researchers. We’re tracking 561 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT02083835Recruiting
Study to improve pain after surgery using patient questionnaires
This trial studies how to better understand and improve pain after surgery by asking patients to complete short questionnaires. It may help hospitals find ways to reduce postoperative pain and better track recovery.
JenaAges 4 years+ - NCT07552701Recruiting
Pain relief methods after gallbladder removal surgery
This study compares two different nerve-blocking techniques to help manage pain after laparoscopic gallbladder surgery. Both methods use ultrasound guidance to deliver numbing medication near nerves, and the trial tests which approach works better for pain relief and overall recovery.
ÇorumAges 18–65 - NCT06821516Recruiting
Comparing two nerve blocks for hip replacement pain
This study compares two different nerve block techniques to manage pain after a total hip replacement. The goal is to find out which method provides better pain relief and recovery.
Istanbul, Türki̇yeAges 18 years+ - NCT07218133Recruiting
Ear Stimulation to Reduce Pain After Spine Surgery
This trial tests whether a gentle electrical stimulation delivered through the ear can reduce inflammation and pain after major spinal fusion surgery. If you are having a long spinal fusion, you might be able to join.
St Louis, MissouriAges 18 years+ - NCT07413055RecruitingPhase 3
Comparing two doses of dexamethasone for dental implant pain
This study tests whether a higher dose of dexamethasone (8 mg) works better than a lower dose (4 mg) for reducing pain after getting a single dental implant. It may help find the best way to manage discomfort after surgery.
MuscatAges 21–80 - NCT07523802Recruiting
Managing pain after gum graft surgery with two methods
This trial tests two different ways to protect and manage pain in the mouth after a gum graft surgery. You would compare a product called Ora-Aid with a custom acrylic stent (a protective cover) to see which helps with healing and reduces discomfort better.
CairoAges 18 years+ - NCT07274215Recruiting
Nerve block injection for pain and nausea after sleeve gastrectomy
This study tests a special numbing injection (called a paragastric block) to see if it reduces pain and nausea after sleeve gastrectomy surgery. If you are having this weight-loss surgery, the injection might help you feel better and recover more comfortably.
IstanbulAges 18–65 - NCT07021105Enrolling by invitation
Comparing nerve blocks for pain after gynecological surgery
This study tests two different types of nerve blocks (called 'plain blocks') to see which one works better for controlling pain after major gynecological surgery. You would receive one of the blocks before surgery, and then use a pump you control to get extra pain medicine as needed.
Adana, SarıçamAges 18–69 - NCT06407518Recruiting
Preoperative medicine for pain relief in colorectal cancer patients with sleep or anxiety issues
This trial tests whether taking a medicine called midazolam before surgery can help with pain after surgery in people with colorectal cancer who have trouble sleeping or feel anxious. You would receive the medicine as a drink before your operation.
Guangzhou, GuangdongAges 18–60 - NCT06765278Recruiting
Nerve block comparison for shoulder surgery pain relief
This trial compares three different types of nerve blocks to manage pain after shoulder arthroscopy. The goal is to find which block works best for reducing pain and improving recovery.
CairoAges 18–70 - NCT06889987Recruiting
Pain block comparison for kidney surgery patients
This study compares two types of ultrasound-guided pain blocks for cancer patients having a kidney removed. It aims to find which block provides better pain control after surgery.
CairoAges 18–65 - NCT07329309Recruiting
Breathing exercises for pain after cesarean
This study tests if a gentle breathing technique called Pranayama can help reduce pain after a planned cesarean. It compares the breathing exercise to usual care to see if it improves recovery.
Konya, KonyaAges 18–35 - NCT05058287RecruitingPhase 3
Steroid shot during low-back surgery
This trial tests whether using a steroid medicine (a steroid shot) around the time of low-back decompression surgery improves pain and recovery. It is for adults having a limited-area laminectomy, and it compares steroid use versus not using it.
New York, New YorkAges 18–85 - NCT05804591RecruitingPhase 4
Pregabalin during weight-loss surgery to reduce pain
This trial tests whether pregabalin can help with pain control for people having laparoscopic sleeve gastrectomy (a weight-loss surgery). It may help reduce the discomfort around surgery and improve the overall recovery experience.
Warsaw, WarsawAges 18 years+ - NCT06020677Recruiting
Latinx children and surgery study
This study looks at how Latinx families manage their child's pain after outpatient surgery. It aims to improve care for Spanish-speaking families.
Orange, CaliforniaAges 2–7 - NCT06404983Recruiting
Opioid-free anesthesia for breast cancer surgery
This study tests whether breast cancer surgery can be done safely without using opioid pain medicines during anesthesia. The goal is to see if avoiding opioids leads to fewer side effects and a smoother recovery.
Ioannina, EpirusAges 18–99 - NCT07002541Recruiting
Nerve block comparison for breast surgery pain
This study tests two different nerve-block methods (PECS-II and ESP) to see which better reduces painkiller use during breast surgery. A special monitor guides how much pain medicine you need. The goal is to help you recover with less opioid side effects.
IstanbulAges 18–80 - NCT07005973Recruiting
Mindfulness app for surgery anxiety
This trial tests if a mobile mindfulness program can help reduce anxiety before surgery. If you feel anxious about an upcoming non-emergency surgery under general anesthesia, you may be able to join.
Hong KongAges 18 years+ - NCT07039812Recruiting
Virtual Reality for Pain During Dressing Changes After Heart Surgery
This study tests if using virtual reality or an eye mask during wound dressing changes can help reduce pain and anxiety after coronary artery bypass surgery. It aims to find a drug-free way to make dressing changes more comfortable.
Istanbul, MarmaraAges 18–65 - NCT07180498Recruiting
Tea tree vs chlorhexidine mouthwash after wisdom tooth removal
This study compares a tea tree oil mouthwash and a standard chlorhexidine mouthwash to see which helps better after wisdom tooth removal. It may help you heal faster and with less discomfort.
SanliurfaAges 18–65 - NCT07412522Recruiting
Pain relief injection for minimally invasive heart bypass surgery
This study tests whether a special injection between the ribs can reduce pain after minimally invasive heart bypass surgery. The injection is given before surgery to help with pain control and may reduce the need for strong pain medicines.
IstanbulAges 18–75 - NCT07452627Recruiting
Comparing Nerve Blocks for Sternotomy Pain
This study compares three different injection techniques (nerve blocks) to reduce pain after heart surgery that cuts through the breastbone. The goal is to find the best way to control pain with fewer side effects.
Bursa, NilüferAges 18–80 - NCT07550348Recruiting
Pain Relief Comparison for Lower Leg Surgery Nerve Block
This study compares two common numbing medications used together versus one alone for nerve-blocking surgery on the lower leg. Researchers want to see which approach works better and lasts longer for pain relief after your procedure.
ErzurumAges 18–65 - NCT06783946Enrolling by invitation
Meditation for pain and anxiety after kidney stone surgery
This study is testing whether guided meditation can help reduce pain, discomfort, and anxiety after a kidney stone removal procedure called ureteroscopy. If you or your child is a teenager or adult scheduled for this surgery, meditation might be a calming tool to try before and after the procedure.
Philadelphia, PennsylvaniaAges 12 years+
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Common questions
- Are there clinical trials for postoperative pain?
- Yes. Clin2 currently lists 561 recruiting postoperative pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a postoperative pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a postoperative pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Postoperative Pain, Acute
- Postoperative Pain Management
- Chronic Postoperative Pain
- Total Knee Arthroplasty (Postoperative Pain)
- POSTOPERATIVE DELIRIUM AND POSTOPERATIVE COGNITIVE DECLINE
- Postoperative Pain After Endodontic Treatment
- Postoperative Pain Following Knee Arthroplasty
- Postoperative Pain Management in Oral Surgery
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.