Clinical trials
Postoperative Pain clinical trials
Below are recruiting postoperative pain clinical trials, each written for real people, not researchers. We’re tracking 539 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07394673Recruiting
Nerve block for pain after shoulder surgery
This trial tests a new ultrasound-guided nerve block for pain relief after shoulder surgery. It aims to improve comfort and reduce the need for pain medications.
BursaAges 18–65 - NCT06743802RecruitingPhase 4
Coenzyme Q10 for pain after lung surgery
This trial tests if taking coenzyme Q10 before and after thoracoscopic lung surgery can reduce pain. It may help you recover more comfortably.
Chongqing, Chongqing MunicipalityAges 18–75 - NCT07232108Recruiting
Pain medicine options for recovery after laparoscopic hysterectomy
This study compares two types of pain medicine given during laparoscopic hysterectomy: one is a morphine shot into the spine, the other is numbing medicine injected around the surgery cuts and into the belly. The goal is to see which helps you recover better and with less pain.
ErzurumAges 18–65 - NCT06817239Recruiting
Low-dose esketamine for preventing confusion after surgery in older adults
This study tests whether a low dose of the medicine esketamine can help prevent confusion after surgery in older adults at higher risk. You may qualify if you are 65 or older, planning a major non-cardiac surgery, and have certain health conditions like high blood pressure or diabetes.
Fuzhou, FujianAges 65–90 - NCT06977009Recruiting
Does tooth grinding relief help with post-dental pain?
This study tests whether reducing a tooth's contact with its opposite tooth before root canal treatment can lower pain after the procedure. It's for people with a dead nerve in a back molar that needs a crown.
Amman, Amman GovernorateAges 18–70 - NCT06925152RecruitingPhase 4
Nerve block for C-section pain in complex surgery history
This study tests a targeted numbing injection (a nerve block) in the belly wall during C-sections to improve pain control and recovery for people who have had multiple or complex abdominal surgeries. It aims to see if this approach reduces the need for strong pain medicines.
Memphis, TennesseeAges 18–50 - NCT04724252RecruitingPhase 2/Phase 3
Gabapentin to help children use less opioid after surgery
This study tests whether gabapentin can reduce how much opioid pain medicine children need after certain major chest or heart surgeries. If it works, it may lower opioid-related side effects while still helping with postoperative pain.
Sacramento, CaliforniaAges Up to 17 years - NCT06054802Enrolling by invitation
Sleep and pain after spine surgery in teens
This study looks at how sleep quality before and after spine surgery affects pain recovery. It uses text messages to check in with participants, so a mobile device is needed.
Columbus, OhioAges 10–18 - NCT05400382Recruiting
Mindfulness for depression and pain after cesarean delivery
This study tests whether a mindfulness program can help new mothers manage pain and depression after a planned cesarean delivery. You might be eligible if you are a woman of color or non-Hispanic White with a history of depression and are scheduled for a planned C-section.
Champaign, IllinoisAges 18–45 - NCT05231460Enrolling by invitationPhase 4
Pain plan study for people before bariatric surgery
This study tests a specific pain-management plan for people who are scheduled for sleeve gastrectomy (done by laparoscopy or robotics). The goal is to find how to control pain safely around the time of surgery while avoiding certain risks and medication issues.
Phoenix, ArizonaAges 18 years+ - NCT07657949Recruiting
Nerve block for pain after breast reduction surgery
This trial tests a specific nerve block to see if it can reduce pain after breast reduction surgery, possibly helping with recovery and lowering the need for strong painkillers.
Sivas, SivasAges 18–65 - NCT06507345Recruiting
Non-opioid pain relief after breast surgery
This trial tests whether non-opioid pain medicines can effectively control pain after mastectomy or lumpectomy, allowing you to go home the same day without needing strong opioids.
Montreal, QuebecAges 18 years+ - NCT07578545Recruiting
Pain management after minimally invasive chest surgery
This study tests whether combining a specific type of chest surgery (using small cameras) with numbing injections around nerves reduces pain and the need for strong pain medications after surgery. Researchers want to see if this approach helps patients recover better with less opioid use.
Antalya, MuratpaşaAges 18–75 - NCT06978179Recruiting
Nerve blocks for pain after lower belly surgery
This trial compares two types of nerve blocks (QL block vs TAP block) to see which one provides better pain relief after lower abdominal surgery. If you are having this surgery, you may be able to join and receive one of these blocks to help manage your pain.
SohagAges 18–65 - NCT07848126Recruiting
Foam rolling after knee replacement surgery
This study tests whether using a foam roller after knee replacement surgery helps reduce pain and improve movement. If you are having your first knee replacement, this may help you recover faster.
Izmir, BalçovaAges 40 years+ - NCT07781930Recruiting
Comparing two pain blocks after kidney laparoscopy
This study compares two types of pain-relieving injections given during kidney surgery to see which one works better. It may help reduce pain after surgery and improve recovery.
CairoAges 18–40 - NCT07674836Recruiting
Comparing two nerve blocks for chronic pain after breast surgery
This study tests two types of nerve blocks (SPSIP and ESP blocks) to see which one works better for long-term pain after a single-sided breast surgery like mastectomy. It aims to find a safer, more effective way to manage chronic pain after surgery.
İzmit, KocaeliAges 18–65 - NCT07650760RecruitingPhase 4
Pain Relief After Gallbladder Removal Surgery
This trial tests whether flushing the abdomen with a numbing medication (bupivacaine) during minimally invasive gallbladder surgery reduces pain after the procedure compared to using saline (salt water) alone.
Wāh, Punjab ProvinceAges 18–60 - NCT07615595Enrolling by invitationPhase 4
Dexamethasone to reduce side effects from spinal anesthesia during cesarean delivery
This study tests whether giving a steroid medication (dexamethasone) before spinal anesthesia can reduce uncomfortable side effects like nausea, vomiting, and low blood pressure during planned cesarean delivery. The goal is to help you feel better during and after your surgery.
Ho Chi Minh City, Ho Chi MinhAges 18 years+ - NCT07334288Recruiting
Numbing injection for pain relief after lower back surgery
This study tests a numbing injection near the spine (retrolaminar block) to reduce pain after lower back surgery with hardware. It could help you use less pain medicine and recover more comfortably.
Santiago, Santiago MetropolitanAges 18–80 - NCT05898035Recruiting
Testing symptoms after root-end dental surgery
This study looks at what symptoms you feel after endodontic microsurgery (a type of root-end tooth procedure). It will help doctors understand what to expect after surgery in properly selected patients.
IrbidAges 18–65 - NCT07197710Recruiting
Imagined acupuncture for pain after spine surgery
This trial tests if imagining acupuncture, guided by a video, can help reduce pain after spinal surgery. It is for adults having their first spine surgery on one or two bones.
Boston, MassachusettsAges 18 years+ - NCT07104825Recruiting
Nerve block for pain after weight loss surgery
This trial tests if a nerve block can help control pain after gastric bypass or sleeve gastrectomy. The goal is to reduce the need for strong pain medicines and improve recovery.
Evanston, IllinoisAges 18–90 - NCT07080892Recruiting
Comparing two ways to give a knee nerve block for pain after knee replacement
This study compares two different ways of giving a nerve block (called iPACK) to see which works better for pain after total knee replacement. The goal is to find the best spot for the injection to help you feel more comfortable after surgery.
BratislavaAges 18–80
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Common questions
- Are there clinical trials for postoperative pain?
- Yes. Clin2 currently lists 539 recruiting postoperative pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a postoperative pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a postoperative pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Postoperative Pain, Acute
- Postoperative Pain Management
- Chronic Postoperative Pain
- Total Knee Arthroplasty (Postoperative Pain)
- POSTOPERATIVE DELIRIUM AND POSTOPERATIVE COGNITIVE DECLINE
- Postoperative Pain After Endodontic Treatment
- Postoperative Pain Following Knee Arthroplasty
- Postoperative Pain Management in Oral Surgery
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.