Clinical trials
Posttraumatic Stress clinical trials
Below are recruiting posttraumatic stress clinical trials, each written for real people, not researchers. We’re tracking 102 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07219056Recruiting
Sound therapy for adults with trauma and addiction
This trial tests a sound-based program (Safe & Sound Protocol) to help adults with both trauma and substance use disorder in residential treatment. It aims to see if this gentle listening therapy can calm the nervous system and support recovery.
Wernersville, PennsylvaniaAges 18–75 - NCT06193161Recruiting
Prolonged Exposure Therapy for PTSD in Immigrants
This trial tests prolonged exposure therapy for immigrants in Sweden who have PTSD. You will receive this online therapy to see if it helps reduce trauma symptoms.
SolnaAges 18 years+ - NCT07176273Recruiting
Personalized PTSD Treatment for Veterans
This trial helps veterans with PTSD choose between two proven talk therapies—Prolonged Exposure (PE) or Cognitive Processing Therapy (CPT)—and uses a smartphone app to support their treatment. The goal is to see which approach works best for each person.
Augusta, GeorgiaAges 18 years+ - NCT07165834Recruiting
Sexuality after sexual trauma: a group therapy study
This study explores how a psychoeducational group can help people reclaim their sexuality after sexual trauma. It aims to understand the struggles and successes of healing in a supportive setting.
SkienAges 18–65 - NCT07146633Recruiting
Testing an EMDR app for PTSD and substance use
This study tests an app that uses EMDR therapy to help people with both PTSD and substance use problems. EMDR is a type of therapy that uses eye movements or taps to help process traumatic memories. You would use the app at home and avoid starting other new therapies during the study.
Toronto, OntarioAges 18 years+ - NCT07105345Recruiting
Cognitive processing therapy trial for PTSD
This trial tests a type of talk therapy called Cognitive Processing Therapy (CPT) to see if it helps people with post-traumatic stress disorder (PTSD). It aims to reduce PTSD symptoms and improve your daily life.
New Taipei City, Banqiao DistrictAges 20–65 - NCT07055633Recruiting
Improving cognitive rehab for veterans with concussion and PTSD
This trial tests a program to help veterans with memory, attention, or thinking problems after a mild concussion (mTBI) and with PTSD. It also looks at depression and sleep issues. The goal is to improve thinking and daily life.
San Diego, CaliforniaAges 18 years+ - NCT07009158RecruitingPhase 1/Phase 2
Ketamine plus therapy for pain and PTSD
This trial tests if ketamine combined with talk therapy helps people with both chronic pain and PTSD. Participants receive ketamine through an IV in group therapy sessions over several weeks, with the goal of reducing pain and PTSD symptoms.
Kingston, OntarioAges 18–64 - NCT06968832Recruiting
Prolonged therapy for PTSD and substance use
This trial tests a therapy that helps people with both post-traumatic stress disorder (PTSD) and a substance use disorder (SUD). You'll receive extended therapy sessions to reduce PTSD symptoms and support your recovery from substance use, while continuing your current substance use treatment.
Jacksonville, FloridaAges 18 years+ - NCT06954025Enrolling by invitationPhase 2
MDMA therapy for PTSD inpatients
This trial tests whether high-dose MDMA, given during intensive inpatient therapy, can help people with PTSD that hasn't improved with other treatments. It takes place at a specialized trauma center and involves several therapy sessions with the drug.
OegstgeestAges 18 years+ - NCT06937892Recruiting
Metacognitive therapy vs. Cognitive therapy for anxiety
This study compares two different types of therapy for anxiety disorders: metacognitive therapy (which focuses on how you think about your thoughts) versus cognitive-behavioral therapy (which works on changing thoughts and behaviors). It may help you find which approach works best for you.
StockholmAges 18 years+ - NCT06820138RecruitingPhase 2
Focused ultrasound treatment for PTSD in veterans
This study tests a non-invasive treatment called focused ultrasound for veterans with PTSD. Focused ultrasound uses sound waves to target specific brain areas without surgery. It aims to reduce PTSD symptoms like distress and anxiety.
Providence, Rhode IslandAges 22–70 - NCT06804525Recruiting
Adapting a mental health survey in Hong Kong
This study adapts a mental health survey for Hong Kong adults. It is open to adults aged 25 and older who live in randomly selected households and can speak Chinese or English.
Hong KongAges 25 years+ - NCT06788678Recruiting
Web-based moral elevation for veterans with PTSD
This trial tests a website designed to help veterans with PTSD feel inspired by stories of others' good deeds, which may reduce PTSD symptoms. You would complete sessions online and answer questions about your experiences.
Temple, TexasAges 18 years+ - NCT05837845RecruitingPhase 2
MDMA plus therapy versus therapy alone for severe PTSD
This Phase 2 study compares MDMA-assisted Cognitive Processing Therapy (a structured talk-therapy) to Cognitive Processing Therapy alone for Veterans with severe PTSD. It aims to see whether adding MDMA helps reduce PTSD symptoms and improve recovery.
Palo Alto, CaliforniaAges 18 years+ - NCT06641115Recruiting
Integrated treatment for opioid use disorder and PTSD
This study tests a combined therapy for people with both opioid use disorder and PTSD. It aims to help you manage both conditions together, rather than treating them separately.
Charleston, South CarolinaAges 18–70 - NCT06630884RecruitingPhase 1
Immune response to trauma and fear
This study looks at how the body's immune and stress systems work together in people who have experienced trauma, by giving a harmless vaccine to temporarily boost inflammation. It may help explain why some people develop PTSD and others don't, which could lead to better treatments.
San Francisco, CaliforniaAges 18–65 - NCT06573970RecruitingPhase 4
Atomoxetine for PTSD and executive function in veterans
This trial tests if the medication atomoxetine can improve thinking and memory in veterans with PTSD and attention difficulties. It may help those who have not responded fully to other treatments.
Charleston, South CarolinaAges 18–75 - NCT06535516Recruiting
Supporting youth and families after tough experiences
This study tests a program to help youth ages 10-15 who have faced child maltreatment, like abuse or neglect. It aims to build resilience in both the youth and their family.
Rochester, New YorkAges 10–15 - NCT06449326Recruiting
Brain imaging and stimulation study for PTSD in veterans
This study uses brain scans and a non-invasive brain stimulation technique called repetitive transcranial magnetic stimulation (rTMS) to help reduce PTSD symptoms in veterans. You may be eligible if you have ongoing PTSD symptoms and are on stable medication.
Albuquerque, New MexicoAges 18–80 - NCT06434766Recruiting
Brain stimulation for PTSD treatment study
This study tests a noninvasive brain stimulation method called iTBS to see if it can help people with post-traumatic stress disorder (PTSD). You would receive the treatment and be monitored for changes in your symptoms.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT06418178RecruitingPhase 2
Optimizing MDMA therapy dose for PTSD in veterans
This trial tests different doses of MDMA (a drug sometimes called 'ecstasy') combined with therapy to see which dose works best for treating PTSD in veterans. The goal is to find a safer, more effective dose to help reduce PTSD symptoms.
The Bronx, New YorkAges 18 years+ - NCT06288711Recruiting
Video therapy for PTSD in people taking opioid medication
This trial tests a therapy called prolonged exposure (a type of talk therapy) delivered via video calls to help people with both opioid use disorder and PTSD. It aims to see if this approach can reduce PTSD symptoms.
Burlington, VermontAges 18 years+ - NCT06234969Recruiting
Brain stimulation for PTSD: a learning study
This study tests whether a non-invasive brain stimulation technique called cTBS can help people with PTSD learn to overcome fear. You will have brain scans and receive stimulation to see if it improves how your brain processes fear-related memories.
Philadelphia, PennsylvaniaAges 18–60
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Common questions
- Are there clinical trials for posttraumatic stress?
- Yes. Clin2 currently lists 102 recruiting posttraumatic stress studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a posttraumatic stress trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a posttraumatic stress trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.