Clinical trials
Posttraumatic Stress clinical trials
Below are recruiting posttraumatic stress clinical trials, each written for real people, not researchers. We’re tracking 101 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06418178RecruitingPhase 2
Optimizing MDMA therapy dose for PTSD in veterans
This trial tests different doses of MDMA (a drug sometimes called 'ecstasy') combined with therapy to see which dose works best for treating PTSD in veterans. The goal is to find a safer, more effective dose to help reduce PTSD symptoms.
The Bronx, New YorkAges 18 years+ - NCT06429293Recruiting
Talk therapy for PTSD and heart health
This study tests whether cognitive behavioral therapy (a type of talk therapy) can improve heart health in people with PTSD. If you have PTSD and are at risk for or have heart disease, you may be able to join.
Boston, MassachusettsAges 18–65 - NCT06449326Recruiting
Brain imaging and stimulation study for PTSD in veterans
This study uses brain scans and a non-invasive brain stimulation technique called repetitive transcranial magnetic stimulation (rTMS) to help reduce PTSD symptoms in veterans. You may be eligible if you have ongoing PTSD symptoms and are on stable medication.
Albuquerque, New MexicoAges 18–80 - NCT06535516Recruiting
Supporting youth and families after tough experiences
This study tests a program to help youth ages 10-15 who have faced child maltreatment, like abuse or neglect. It aims to build resilience in both the youth and their family.
Rochester, New YorkAges 10–15 - NCT06608979Recruiting
Trauma screening and violence prevention for women in addiction treatment
This study offers trauma screening and a program to help prevent interpersonal violence for women who are currently receiving treatment for substance use. It aims to understand how these services can improve safety and well-being.
Greenville, South CarolinaAges 18 years+ - NCT06630884RecruitingPhase 1
Immune response to stress after trauma
This study looks at how the immune system responds to a mild stress (a typhoid vaccine) in people who have been through trauma but do not have PTSD. It may help understand why some people are more susceptible to inflammation after trauma.
San Francisco, CaliforniaAges 18–60 - NCT06641115Recruiting
Integrated treatment for opioid use disorder and PTSD
This study tests a combined therapy for people with both opioid use disorder and PTSD. It aims to help you manage both conditions together, rather than treating them separately.
Charleston, South CarolinaAges 18–70 - NCT06706323Recruiting
Depression after heart surgery study
This study looks at depressive symptoms in people who have had heart bypass surgery. It aims to understand how patients feel emotionally after surgery and may help improve care.
ZurichAges 18–90 - NCT06573970RecruitingPhase 4
Atomoxetine for PTSD and executive function in veterans
This trial tests if the medication atomoxetine can improve thinking and memory in veterans with PTSD and attention difficulties. It may help those who have not responded fully to other treatments.
Charleston, South CarolinaAges 18–75 - NCT06804525Recruiting
Adapting a mental health survey in Hong Kong
This study adapts a mental health survey for Hong Kong adults. It is open to adults aged 25 and older who live in randomly selected households and can speak Chinese or English.
Hong KongAges 25 years+ - NCT06937892Recruiting
Metacognitive therapy vs. Cognitive therapy for anxiety
This study compares two different types of therapy for anxiety disorders: metacognitive therapy (which focuses on how you think about your thoughts) versus cognitive-behavioral therapy (which works on changing thoughts and behaviors). It may help you find which approach works best for you.
StockholmAges 18 years+ - NCT06968832Recruiting
Prolonged therapy for PTSD and substance use
This trial tests a therapy that helps people with both post-traumatic stress disorder (PTSD) and a substance use disorder (SUD). You'll receive extended therapy sessions to reduce PTSD symptoms and support your recovery from substance use, while continuing your current substance use treatment.
Jacksonville, FloridaAges 18 years+ - NCT07055633Recruiting
Improving cognitive rehab for veterans with concussion and PTSD
This trial tests a program to help veterans with memory, attention, or thinking problems after a mild concussion (mTBI) and with PTSD. It also looks at depression and sleep issues. The goal is to improve thinking and daily life.
San Diego, CaliforniaAges 18 years+ - NCT07105345Recruiting
Cognitive processing therapy trial for PTSD
This trial tests a type of talk therapy called Cognitive Processing Therapy (CPT) to see if it helps people with post-traumatic stress disorder (PTSD). It aims to reduce PTSD symptoms and improve your daily life.
New Taipei City, Banqiao DistrictAges 20–65 - NCT07146633Recruiting
Testing an EMDR app for PTSD and substance use
This study tests an app that uses EMDR therapy to help people with both PTSD and substance use problems. EMDR is a type of therapy that uses eye movements or taps to help process traumatic memories. You would use the app at home and avoid starting other new therapies during the study.
Toronto, OntarioAges 18 years+ - NCT07165834Recruiting
Sexuality after sexual trauma: a group therapy study
This study explores how a psychoeducational group can help people reclaim their sexuality after sexual trauma. It aims to understand the struggles and successes of healing in a supportive setting.
SkienAges 18–65 - NCT07176273Recruiting
Personalized PTSD Treatment for Veterans
This trial helps veterans with PTSD choose between two proven talk therapies—Prolonged Exposure (PE) or Cognitive Processing Therapy (CPT)—and uses a smartphone app to support their treatment. The goal is to see which approach works best for each person.
Augusta, GeorgiaAges 18 years+ - NCT07220681Recruiting
Integrated Care for PTSD
This study tests whether combining different treatments can help Veterans with PTSD. It focuses on those who can receive Cognitive Processing Therapy (CPT) at a VA site.
Little Rock, ArkansasAges 18 years+ - NCT07238192Recruiting
Testing a therapy to reduce suicide risk in veterans with PTSD
This trial is testing whether a therapy called Cognitive Processing Therapy (CPT), given in an intensive format, can reduce suicide risk in veterans and active duty service members with PTSD. It aims to see if this approach is more effective than standard care at preventing suicidal thoughts and behaviors.
Fort Hood, TexasAges 18 years+ - NCT07250061Recruiting
Self-help PTSD program for women veterans
This study tests a self-guided program to help women veterans with PTSD. You would work through coping skills on your own, with support from a group of other women veterans.
Boston, MassachusettsAges 18 years+ - NCT07317206RecruitingPhase 2
Ayahuasca vs Esketamine for PTSD
This trial tests two treatments—ayahuasca and esketamine—to see if they can help people with PTSD. It's for people who have PTSD and no other health problems.
Ribeirão Preto, São PauloAges 18–65 - NCT05457985Recruiting
Adaptive app coaching for PTSD in community health clinics
This study tests a flexible (adaptive) approach using a mobile app to help improve treatment outcomes for posttraumatic stress disorder (PTSD) for people getting care at participating community health clinics. It may help you get more tailored support between visits.
Baldwin, MichiganAges 18 years+ - NCT02757339Enrolling by invitation
Study of brain differences in dissociation after abuse
This study looks at brain activity and biology in women who have PTSD or dissociative identity disorder (DID) with a history of childhood abuse or neglect. It may help researchers understand what causes “traumatic dissociation” and how it develops.
Belmont, MassachusettsAges 18–89 - NCT07630428Enrolling by invitation
Support programs after sexual assault medical exam
This study tests two support programs—STAR and TextSTAR—designed to help people after a sexual assault medical exam. The goal is to see which approach better supports your recovery and connects you with resources.
Louisville, KentuckyAges 18 years+
Hear when a new Posttraumatic Stress trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for posttraumatic stress?
- Yes. Clin2 currently lists 101 recruiting posttraumatic stress studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a posttraumatic stress trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a posttraumatic stress trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.