Clinical trials
Pregnancy, High Risk clinical trials
Below are recruiting pregnancy, high risk clinical trials, each written for real people, not researchers. We’re tracking 361 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06822439Recruiting
Remote fetal monitoring for high-risk pregnancies
This study tests if remote monitoring of your baby's heartbeat from home is a safe and effective option for high-risk pregnancies. It may reduce the need for frequent hospital visits.
Boston, MassachusettsAges 18 years+ - NCT07281339Recruiting
Hypnobreastfeeding education for high-risk pregnancy
This trial tests if hypnosis-enhanced breastfeeding education helps high-risk pregnant women who haven't given birth before. It may improve breastfeeding success and reduce stress.
AmasyaAges Any age - NCT06529042Enrolling by invitation
Sickle Cell Risk in Pregnancy Tool Study
This study is developing a risk assessment tool to help predict complications in pregnant women with sickle cell disease. It reviews medical records from women who have received prenatal care and given birth at participating hospitals.
Baltimore, MarylandAges 16–60 - NCT05763069Enrolling by invitation
Home monitoring for high-risk pregnancies
This study tests whether checking certain pregnancy warning signs at home (with monitoring technology) can help manage high-risk pregnancies. It may allow closer follow-up while you stay at home, aiming to improve safety and decision-making.
OsloAges 18–50 - NCT07380217Recruiting
Using heart pump support for complex high-risk procedures
This trial is testing whether using a special heart pump (PulseCath iVAC2L) during complex, high-risk angioplasty can help people with very weak hearts. It's for people who need a procedure for complicated coronary artery blockages.
AmsterdamAges 18 years+ - NCT07420465Recruiting
Heart and metabolic risks in pregnancy and after birth
This study looks at heart and metabolic health during late pregnancy and after delivery, tracking both healthy women and those with complications like high blood pressure or diabetes in pregnancy. The goal is to understand how these risks change and what can be done to improve long-term health.
AccraAges 18–45 - NCT05345860Recruiting
Using MRD results to guide extra treatment after breast surgery
This trial checks “MRD” (tiny leftover cancer signals after surgery) to help decide the best additional treatment for early-stage breast cancer. It may help tailor therapy so you get the most useful medicines while avoiding unnecessary treatment.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06430853Enrolling by invitation
Pregnancy support study for moms with anxiety or depression
This study tests if a mental health program during pregnancy can help mothers with past or current anxiety or depression. You'll get support and you may feel better and have a healthier pregnancy.
Stanford, CaliforniaAges 18 years+ - NCT05317585Recruiting
Continuous glucose monitor use during early pregnancy with type 2 diabetes
This study tests whether using a continuous glucose monitor during pregnancy is useful for people with type 2 diabetes. It may help track blood sugar levels more closely to support safer pregnancy care.
Worcester, MassachusettsAges 18 years+ - NCT07720284RecruitingPhase 3
Testing new drugs for high-risk bladder cancer after surgery
This trial tests a new combination of drugs (Dato-DXd plus rilvegostomig) against standard treatments for people with high-risk, muscle-invasive bladder cancer that has been surgically removed. The goal is to see if the new treatment reduces the chance of the cancer coming back.
Hot Springs, ArkansasAges 18 years+ - NCT06327269RecruitingEarly Phase 1
Targeted therapy after liver transplant for high-risk liver cancer
This trial tests a targeted therapy (lenvatinib) given after a living-donor liver transplant to prevent high-risk liver cancer from coming back. It is for people whose cancer is aggressive or did not respond well to previous treatments.
Kaohsiung CityAges 18–75 - NCT07301866RecruitingPhase 1/Phase 2
Testing an improved dose of UM171 for cord blood transplant
This trial tests a higher dose of UM171 to make cord blood transplants safer and more effective for people with certain blood cancers or bone marrow diseases. It aims to help patients who don't have a suitable donor.
Montreal, QuebecAges 18–67 - NCT07549321RecruitingPhase 2/Phase 3
Hu14 Immunotherapy for High-Risk Neuroblastoma in Children
This study tests a new antibody-based immunotherapy called hu14 for children and young adults with high-risk neuroblastoma (an aggressive childhood cancer that has spread). The treatment is designed to help the immune system fight cancer cells.
Aurora, ColoradoAges 1.5 years–18 years - NCT06488482RecruitingPhase 3
Short immunotherapy after melanoma surgery
This trial tests whether giving a shorter course of immunotherapy after surgery can help prevent melanoma from coming back. It is for people with high-risk melanoma who have had the cancer fully removed.
HelsinkiAges 18 years+ - NCT06574126RecruitingPhase 2
CAR T-cell therapy for high-risk smoldering myeloma
This trial tests a new CAR T-cell therapy (cilta-cel) for people with high-risk smoldering multiple myeloma. It aims to prevent progression to active myeloma.
SalamancaAges 18 years+ - NCT06745687Recruiting
BCMA/CD3 antibody for high-risk smoldering myeloma
This trial tests a new medicine called a BCMA/CD3 bispecific antibody for people with a very early form of multiple myeloma called high-risk smoldering myeloma. The goal is to see if this treatment can stop the disease from getting worse.
TianjinAges 18–78 - NCT03383575RecruitingPhase 2
Azacitidine plus enasidenib for IDH2-mutant MDS
This trial tests whether combining azacitidine with enasidenib helps people with myelodysplastic syndrome (MDS) that has an IDH2 mutation. It’s designed for people who are either new to “hypomethylating” treatment or whose MDS returned/worsened after it.
Baltimore, MarylandAges 12 years+ - NCT06839456RecruitingPhase 1/Phase 2
Stem cell addback to prevent infections after transplant
This trial tests whether adding back certain immune cells after a stem cell transplant can help prevent serious viral or fungal infections. It's for children and young adults up to age 25 who need a transplant for a blood cancer or other curable disease.
Philadelphia, PennsylvaniaAges 1 month–25 years - NCT07366801RecruitingPhase 2/Phase 3
Preventing graft versus host disease in children with blood cancer
This trial tests if adding special immune cells (Treg cells) to a stem cell transplant from a half-matched donor can lower the risk of graft versus host disease (a serious side effect where donor cells attack the patient's body) in children and young adults with blood cancers.
MoscowAges 1–25 - NCT07560813Recruiting
Nutrition and food support for pregnant people with diabetes
This study helps pregnant people with type 1 or type 2 diabetes who struggle to afford healthy food. You'll receive nutrition counseling and access to fresh food through a local program to help manage your blood sugar and have a healthier pregnancy.
Columbus, OhioAges 18 years+ - NCT04861103RecruitingPhase 4
Testing a blood thinner plan during pregnancy
This study looks at how people’s blood and clotting behave during pregnancy when taking a specific blood thinner called low molecular weight heparin (LMWH) three times a day. It may help doctors fine-tune how safely and effectively LMWH is used during pregnancy.
Orange, CaliforniaAges 18 years+ - NCT05904145Recruiting
Study of mother and baby health during early pregnancy
This study follows pregnant women to better understand health needs for mothers and newborns, starting in the first part of pregnancy. You may be able to join if you live nearby, are at least the required age, and your pregnancy is confirmed to be under 20 weeks.
KintampoAges 15 years+ - NCT03848962Recruiting
Share leftover or collected samples for research
This study helps collect and share human samples (like blood or other specimens) so researchers can do new studies. It’s mainly about providing samples for research use, not testing a treatment on you.
Huntsville, AlabamaAges 1 month–89 years - NCT05124808Recruiting
Tight blood sugar targets in pregnant women with gestational diabetes
This study compares a tighter blood sugar goal versus a standard goal in pregnant people with gestational diabetes who are also overweight or obese. It may help find whether stricter blood sugar control improves pregnancy outcomes.
Birmingham, AlabamaAges 18–45
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Common questions
- Are there clinical trials for pregnancy, high risk?
- Yes. Clin2 currently lists 361 recruiting pregnancy, high risk studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pregnancy, high risk trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pregnancy, high risk trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.