Clinical trials
Premature clinical trials
Below are recruiting premature clinical trials, each written for real people, not researchers. We’re tracking 265 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06399861Recruiting
Humidity in incubators for tiny infants
This trial is testing different humidity levels in incubators for very premature babies (born before 25 weeks of pregnancy) to see which level works best. The goal is to improve care for these tiny infants in the neonatal intensive care unit (NICU).
Birmingham, AlabamaAges birth–1 day - NCT07622563Recruiting
Automatic oxygen control for premature babies on breathing support
This trial tests a device that automatically adjusts oxygen levels for premature babies who need help breathing through tubes or masks in their nose. The goal is to keep oxygen levels in a safer, more stable range without needing staff to manually adjust it constantly.
LondonAges 5 months–8 months - NCT05243043Recruiting
Help for mothers needing premature baby resuscitation
This trial tests an interactive phone or app-style tool to help mothers prepare for and understand what happens if their premature baby needs breathing support at birth. It may help you feel more informed and supported during a high-stress time.
Iowa City, IowaAges 18–60 - NCT04270734Recruiting
Brain-wave study of hearing timing from babyhood to adulthood
This study looks at brain activity (brain waves) when babies hear sounds with timing, and how that changes with age. It may help researchers understand early brain development in hearing and processing sounds.
AmiensAges birth–1 day - NCT07073352Recruiting
Childhood stress and blood vessel aging in young adults
This study looks at how childhood stress might affect blood vessels and aging in young adults. It tests if a certain protein (SIRT1) is linked to early blood vessel aging.
Iowa City, IowaAges 18–30 - NCT06642285Recruiting
Preventing nasal injuries in preterm babies on breathing support
This study tests if using special care steps can prevent nose sores in preterm babies who need breathing support through a mask or nasal prongs. It may help protect your baby's delicate nose from injury.
Kafr ash Shaykh, Kafr el-Sheikh GovernorateAges 7 months–9 months - NCT05011149RecruitingPhase 3
Medicine for early treatment of a leaking heart vessel
This trial studies whether giving medicine soon can help preterm babies with a patent ductus arteriosus (a temporary leaking blood vessel in the heart). It aims to see if early treatment improves outcomes for very early gestational age infants.
Orange, CaliforniaAges Up to 3 days - NCT05609877Recruiting
Testing LISA breathing treatment for very preterm newborns
This trial is studying whether giving a lung “surfactant” medicine through a thin tube (called LISA) helps very premature babies with breathing problems. It aims to see if this approach improves care for babies born around 24 to 30 weeks gestation who still need oxygen support.
AalborgAges 6 months–7 months - NCT00710112Recruiting
Genetic risk study in very low birth-weight babies
This study looks at genetic differences to understand why some very low birth-weight babies develop certain health problems. It may help doctors predict risk and tailor care for these babies.
Milwaukee, WisconsinAges Any age - NCT07660393Recruiting
Virtual reality glasses for women with early water breaking
This study tests whether wearing virtual reality glasses can help reduce stress and anxiety in pregnant women who have experienced premature rupture of membranes (water breaking early). It is designed for women carrying a single baby who are between 24 and 37 weeks of pregnancy.
KonyaAges 18–50 - NCT05469984Recruiting
Two antibiotic plans for water breaking before labor
This trial compares two different “preventive” antibiotic schedules for pregnant people whose water breaks more than 18 hours before labor, or who go into preterm labor. The goal is to see which plan better helps mother and baby by reducing infection-related complications.
NahariyaAges 18–48 - NCT07410442Recruiting
Distal shoe safety guidelines for kids
This study looks at how safe and well-tolerated a dental device called a distal shoe is for children who need it. It will help create better care guidelines for kids getting this treatment.
Gainesville, FloridaAges 3–9 - NCT05617833RecruitingPhase 1
Test EPO and melatonin for brain bleeding in very preterm babies
This Phase 1 trial studies whether giving erythropoietin (EPO) and melatonin is safe in very preterm infants who have bleeding in the brain (intraventricular hemorrhage) or significant nearby brain injury. It aims to see if these medicines can be given safely during the early days after birth.
St. Petersburg, FloridaAges 12 hours–2 months - NCT06458114Recruiting
Feelings of caregivers after palliative care for extremely preterm babies
This study asks caregivers about their feelings after providing palliative care to extremely preterm babies in the delivery room. It aims to understand their experiences to improve support for caregivers.
ReimsAges 18 years+ - NCT07338370Recruiting
PGE2 levels and heart duct closure in preterm babies
This trial measures a substance called prostaglandin E2 (PGE2) in preterm babies to see if it can predict whether a heart blood vessel (ductus arteriosus) will close on its own or need treatment. This could help doctors decide when to use medication to close the vessel.
Cairo, AbbasiaAges 1 day–1 week - NCT05734768Recruiting
Study of anxiety and depression in parents after preterm birth
This study compares how parents feel (anxiety and depression symptoms) after having a baby born preterm versus a full-term baby. It also looks at early “building blocks” of thinking and social development in the child.
ReimsAges 18 years+ - NCT03797183Recruiting
Check heart and lung function using a painless chest scan
This study uses a noninvasive scan that measures electrical signals across the chest to better understand breathing and heart-related circulation problems. It may help doctors learn what to monitor and how conditions like lung/airway pressure and vessel narrowing progress.
Aurora, ColoradoAges 2 weeks–40 years - NCT03819933Recruiting
Family counseling support for very early preterm birth
This trial studies a better way to provide counseling to families when a baby is expected to be born very early (between about 22 and 25 weeks). It may help you and your partner feel more prepared for the NICU and what to expect next.
Boston, MassachusettsAges 18–99 - NCT03906435Recruiting
Cognitive therapy to prevent problems for very premature NICU babies
This study offers a counseling approach to help prevent “Vulnerable Child Syndrome” in babies born very early and cared for in the NICU. It focuses on support during the early months after birth and compares outcomes for families getting the therapy versus usual support.
Dallas, TexasAges Any age - NCT07419438Recruiting
Airway device study for preterm babies needing breathing help
This study tests a supraglottic airway device (a tube that sits above the voice box) versus a face mask for helping premature babies breathe right after birth. It may help doctors choose the best way to support your baby's first breaths.
Philadelphia, PennsylvaniaAges birth–1 day - NCT04021485Recruiting
Smaller steroid dose test for early-born children’s brain outcomes
This study checks whether giving a lower dose of a steroid medicine (betamethasone) to mothers before birth produces similar brain and thinking outcomes in children born very early (before 32 weeks). It may help reduce medicine exposure while keeping developmental results the same.
Paris, PaAges 5–6 - NCT04114435Recruiting
Heart and lung testing in extremely premature babies
This study looks at how the hearts and lungs work in babies born very early (before 29 weeks). It may help researchers understand why some babies develop breathing and heart circulation problems and how to measure their recovery.
Montreal, QuebecAges 1 week–5 years - NCT04270045Recruiting
Breathing test in babies with bronchopulmonary dysplasia
This trial studies a breathing measurement test (forced oscillometry) in babies who were born early and have bronchopulmonary dysplasia (BPD), a long-term lung condition. It may help doctors better understand how babies’ lungs are working and guide future care.
Kansas City, MissouriAges Any age - NCT04294368Recruiting
Fortifying donor breast milk for very premature babies
This study tests whether adding extra nutrition (fortifying) to donated breast milk helps very premature infants grow better and safely. You might be offered a fortified donor milk feeding plan if your baby meets the timing and medical criteria.
New York, New YorkAges 1 day–3 weeks
Hear when a new Premature trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for premature?
- Yes. Clin2 currently lists 265 recruiting premature studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a premature trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a premature trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.