Clinical trials
Primary Open Angle Glaucoma clinical trials
Below are recruiting primary open angle glaucoma clinical trials, each written for real people, not researchers. We’re tracking 57 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05564091Recruiting
Add a minimally invasive canaloplasty step to cataract surgery
This trial compares standard cataract surgery alone versus cataract surgery plus a procedure to improve fluid drainage in the eye. It is intended for people with mild to moderate open-angle glaucoma, to see if adding this step helps control eye pressure and preserve vision.
Sugar Land, TexasAges 55 years+ - NCT05786196Recruiting
Testing canaloplasty surgery for mild to moderate glaucoma
This study tests how well a specific glaucoma surgery (canaloplasty) works on its own for people with mild to moderate primary open-angle glaucoma. It may help if drops (eye medicines) do not work well for you or you need fewer eye drops.
DüsseldorfAges 22 years+ - NCT06933836Recruiting
DSLT laser for newly diagnosed open-angle glaucoma
This trial tests a laser treatment called DSLT in people recently diagnosed with open-angle glaucoma who have never had any other glaucoma treatment. It aims to see how well the laser lowers eye pressure.
Mesa, ArizonaAges 30 years+ - NCT06885827Recruiting
Vitamin mix for people with glaucoma
This trial tests whether taking a daily mix of B vitamins (B6, B9, B12) and choline can help slow vision loss in people with certain types of glaucoma. You would take the vitamins or a placebo (inactive pill) for up to 2 years.
Stockholm, Stockholm CountyAges 18 years+ - NCT07147647Recruiting
Laser treatment for lowering eye pressure in Black patients with glaucoma
This trial tests a laser procedure called DSLT to reduce eye pressure in Black patients with mild to moderate open-angle glaucoma. It aims to see if this treatment works well as a first step before using eye drops.
Elkridge, MarylandAges 18 years+ - NCT03921931Recruiting
Test retinal responses to light in healthy eyes or eye disease
This is a small pilot study that measures how parts of the retina change before and after light stimulation. It may help researchers understand eye function in people with normal vision or specific eye conditions like glaucoma or dry age-related macular degeneration (AMD).
Vienna, State of ViennaAges 18 years+ - NCT07076303Recruiting
Laser treatment for new glaucoma patients without prior medication
This study tests a new laser treatment called DSLT for people who have just been diagnosed with open-angle glaucoma or a similar condition like ocular hypertension. It aims to see if the laser can lower eye pressure by at least 20% after six months without needing any eye drops.
Plymouth Meeting, PennsylvaniaAges 18 years+ - NCT03870230Recruiting
Study of eye blood-flow signals in glaucoma and healthy eyes
This study compares eye blood-flow/brain-eye communication signals in people with glaucoma (or high eye pressure) versus people with normal eye tests. It may help researchers understand how glaucoma develops and progresses.
ViennaAges 18 years+ - NCT03423758Recruiting
Genetic study of eye diseases: PXF, angle-closure and open glaucoma
This study looks at blood or DNA-related factors that may explain why certain glaucoma and related eye conditions happen. It may help researchers understand risk and causes across different glaucoma types.
ViennaAges 21–105 - NCT07063537Recruiting
Virtual reality eye test for glaucoma patients
This trial tests whether a virtual reality device can accurately measure your field of vision compared to standard tests. If you have primary open-angle glaucoma and can perform a visual field test, you may be able to participate.
Halifax, Nova ScotiaAges 18 years+ - NCT07009236Recruiting
MINIject S+ for open angle glaucoma
This trial tests a tiny implant called MINIject S+ to lower eye pressure in people with open angle glaucoma that isn't well controlled with eye drops. It may be done alone or with cataract surgery.
Santa Rosa de CopánAges 20 years+ - NCT05439161Recruiting
XEN gel stent compared with trabeculectomy for open-angle glaucoma
This trial compares two glaucoma operations to see which works better at lowering eye pressure and keeping the eye stable. It’s for adults with open-angle glaucoma who are eligible for either surgery and can attend follow-up visits.
SalzburgAges 18 years+ - NCT06991270Recruiting
Glaucoma surgery study for people with cataracts
This trial tests a surgical system for people with mild to moderate open-angle glaucoma. It may be an option if you are having cataract surgery or have already had it, and your eye pressure is not well controlled with medications.
Panama CityAges 45 years+ - NCT06925477Enrolling by invitation
New vs. standard laser for open-angle glaucoma
This study compares a new way of doing laser treatment for open-angle glaucoma versus the standard method. The goal is to see which approach works better at lowering eye pressure and protecting vision.
Charleston, South CarolinaAges 18 years+ - NCT06921317RecruitingPhase 1/Phase 2
Gene therapy for advanced glaucoma
This trial tests a gene therapy treatment called GVB-2001 for people with primary open angle glaucoma. It involves a one-time injection into the eye to help lower eye pressure, and could be an option if you have tried other treatments that haven't worked well enough.
Suzhou, JiangsuAges 18–75 - NCT06822738RecruitingPhase 3
Study of XEN63 gel stent for glaucoma patients
This trial tests a new gel stent (XEN63) to lower eye pressure in adults with glaucoma. It compares two ways of putting the stent in the eye, and may help people who have not had success with other treatments.
Glendale, ArizonaAges 45 years+ - NCT06685211Recruiting
Electrical stimulation for vision in glaucoma
This trial tests whether gentle electrical stimulation can help improve vision in people with moderate vision loss from glaucoma. It might offer a new way to strengthen remaining vision.
Palo Alto, CaliforniaAges 18 years+ - NCT06682962Recruiting
Electrical stimulation for vision loss from glaucoma
This trial tests if a gentle electrical stimulation on the eye can slow or improve vision loss in people with open-angle glaucoma. It uses a device you can use at home after training.
MainzAges 40 years+ - NCT04396002Recruiting
Study of life movement and vision loss in older adults
This study looks at whether how far and how much you move around each day is linked to glaucoma and vision field loss in older adults. It may help researchers understand what affects vision changes over time.
Birmingham, AlabamaAges 18–100 - NCT06246136Recruiting
Laser treatment for glaucoma during cataract surgery
This study tests a new laser treatment (ELIOS) for people with open-angle glaucoma who also need cataract surgery. It aims to see if the laser is safe and effective at lowering eye pressure while removing the cataract.
LeuvenAges 40 years+ - NCT00221897Recruiting
Eye test study to help diagnose glaucoma
This study tests new ways to evaluate eyes to help diagnose glaucoma and related eye conditions. You may be able to join if you’re an adult with normal eye health or with concerns like myopia, glaucoma suspicion, or ocular hypertension.
La Jolla, CaliforniaAges 18 years+ - NCT05940623Recruiting
Home eye pressure monitoring for glaucoma
This study tests whether measuring your eye pressure at home with a special device can help control glaucoma and slow its progression. It may offer a more convenient way to track your condition between doctor visits.
Wong Chuk HangAges 18 years+ - NCT05264818Recruiting
Study measures eye surface sugar layer in glaucoma
This study looks at a thin “sugar coating” on the inside surface of the eye (the endothelial glycocalyx) in people with primary open-angle glaucoma and compares it with people without optic nerve disease. The results may help researchers better understand how glaucoma affects the eye.
ParisAges 18 years+ - NCT05557721Enrolling by invitation
Micropulse laser for open-angle or pseudoexfoliation glaucoma
This study tests a specific eye laser treatment (micropulse) for people with open-angle or pseudoexfoliation glaucoma. It may help lower eye pressure, and the study also checks whether patients can follow the treatment plan and follow-up visits.
Skövde, Västra Götaland CountyAges 18 years+
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Common questions
- Are there clinical trials for primary open angle glaucoma?
- Yes. Clin2 currently lists 57 recruiting primary open angle glaucoma studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a primary open angle glaucoma trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a primary open angle glaucoma trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.