Clinical trials
Primary Open Angle Glaucoma clinical trials
Below are recruiting primary open angle glaucoma clinical trials, each written for real people, not researchers. We’re tracking 58 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06792422RecruitingPhase 4
Oral semaglutide for open-angle glaucoma
This trial tests if an oral medication called semaglutide can help people with open-angle glaucoma. It aims to see if it can protect the optic nerve and manage eye pressure.
Glostrup MunicipalityAges 45 years+ - NCT06865235Recruiting
Glaucoma and cataract surgery with a new device
This trial tests a surgery that combines cataract removal with a new technique to lower eye pressure in people who have both primary open-angle glaucoma and cataracts. It aims to see if this combined surgery is safe and effective.
Belo Horizonte, Minas GeraisAges 40 years+ - NCT06885827Recruiting
Vitamin mix for people with glaucoma
This trial tests whether taking a daily mix of B vitamins (B6, B9, B12) and choline can help slow vision loss in people with certain types of glaucoma. You would take the vitamins or a placebo (inactive pill) for up to 2 years.
Stockholm, Stockholm CountyAges 18 years+ - NCT06921317RecruitingPhase 1/Phase 2
Gene therapy for advanced glaucoma
This trial tests a gene therapy treatment called GVB-2001 for people with primary open angle glaucoma. It involves a one-time injection into the eye to help lower eye pressure, and could be an option if you have tried other treatments that haven't worked well enough.
Suzhou, JiangsuAges 18–75 - NCT06933836Recruiting
DSLT laser for newly diagnosed open-angle glaucoma
This trial tests a laser treatment called DSLT in people recently diagnosed with open-angle glaucoma who have never had any other glaucoma treatment. It aims to see how well the laser lowers eye pressure.
Mesa, ArizonaAges 30 years+ - NCT06991270Recruiting
Glaucoma surgery study for people with cataracts
This trial tests a surgical system for people with mild to moderate open-angle glaucoma. It may be an option if you are having cataract surgery or have already had it, and your eye pressure is not well controlled with medications.
Panama CityAges 45 years+ - NCT07009236Recruiting
MINIject S+ for open angle glaucoma
This trial tests a tiny implant called MINIject S+ to lower eye pressure in people with open angle glaucoma that isn't well controlled with eye drops. It may be done alone or with cataract surgery.
Santa Rosa de CopánAges 20 years+ - NCT07063537Recruiting
Virtual reality eye test for glaucoma patients
This trial tests whether a virtual reality device can accurately measure your field of vision compared to standard tests. If you have primary open-angle glaucoma and can perform a visual field test, you may be able to participate.
Halifax, Nova ScotiaAges 18 years+ - NCT07076303Recruiting
Laser treatment for new glaucoma patients without prior medication
This study tests a new laser treatment called DSLT for people who have just been diagnosed with open-angle glaucoma or a similar condition like ocular hypertension. It aims to see if the laser can lower eye pressure by at least 20% after six months without needing any eye drops.
Plymouth Meeting, PennsylvaniaAges 18 years+ - NCT07147647Recruiting
Laser treatment for lowering eye pressure in Black patients with glaucoma
This trial tests a laser procedure called DSLT to reduce eye pressure in Black patients with mild to moderate open-angle glaucoma. It aims to see if this treatment works well as a first step before using eye drops.
Elkridge, MarylandAges 18 years+ - NCT07235592Recruiting
Preserflo MicroShunt study for open-angle glaucoma
This trial is testing a small device called the PRESERFLO MicroShunt to lower eye pressure in people with open-angle glaucoma. It may be an option if your eye pressure stays high even with maximum eye drops.
ViennaAges 18–85 - NCT07310719Recruiting
Comparing laser versus eye drops for new glaucoma patients
This trial compares two first treatments—laser therapy (SLT) or daily eye drops (latanoprost)—to lower eye pressure in people newly diagnosed with open-angle glaucoma or high eye pressure. It aims to find which approach works better as an initial therapy.
Ikeja, LagosAges 18–90 - NCT07322965Recruiting
Citicoline and DHA supplement for glaucoma patients
This trial tests whether a dietary supplement (DHA + citicoline) can help protect vision in people with glaucoma. You may qualify if you have confirmed glaucoma in at least one eye and are between 50 and 75 years old.
Barcelona, BarcelonaAges 50–75 - NCT07335211RecruitingPhase 3
Testing a new eye drop for glaucoma or high eye pressure
This trial tests a new medicine called HUC3-637 for people with primary open-angle glaucoma or ocular hypertension. It aims to see if it safely lowers eye pressure.
SeoulAges 19 years+ - NCT07358650Recruiting
MIST device for lowering eye pressure in glaucoma
This study tests a new device called MIST that is placed inside the eye to help lower eye pressure in people with primary open-angle glaucoma. It may be an option for those whose pressure is still too high despite using eye drops.
Dieppe, New BrunswickAges 40 years+ - NCT07390890Recruiting
DSLT to reduce glaucoma eye drops
This trial is testing a laser treatment called DSLT to see if it can help people with glaucoma use fewer eye drops. It may be a good option if your eye pressure is already controlled with medication and you haven't had glaucoma surgery before.
Largo, FloridaAges Any age - NCT00221897Recruiting
Eye test study to help diagnose glaucoma
This study tests new ways to evaluate eyes to help diagnose glaucoma and related eye conditions. You may be able to join if you’re an adult with normal eye health or with concerns like myopia, glaucoma suspicion, or ocular hypertension.
La Jolla, CaliforniaAges 18 years+ - NCT07447011Recruiting
Glaucoma treatment response with sleep apnea lifestyle changes
This trial tests whether lifestyle changes can help open-angle glaucoma in people who also have obstructive sleep apnea and are obese. It may offer a non-drug way to manage both conditions.
Giza, DokkiAges 30–50 - NCT07454447Recruiting
Eye exam after new glaucoma surgery
This trial uses a special ultrasound to look at the eye after a certain type of glaucoma surgery. It helps doctors see how well the surgery is working for people with open-angle glaucoma.
Minya, Minya GovernorateAges Any age - NCT07462000Recruiting
Eye fluid and tissue analysis in glaucoma and cataract
This study collects eye fluid and tissue samples during planned cataract or combined cataract-glaucoma surgery to analyze differences between people with and without glaucoma. It may help researchers understand eye disease better.
WarsawAges 18 years+ - NCT07523139Recruiting
Eye Structure Study in Angle-Closure Glaucoma
This research study uses ultrasound imaging to examine the internal structures of the eye in people with angle-closure glaucoma (a type of increased eye pressure) and compares them to healthy eyes. Understanding these structures may help doctors better diagnose and treat this eye condition.
BeijingAges 30–79 - NCT07599241Recruiting
Exercise Program for Older Women With Thyroid, Eye, and Liver Conditions
This study tests whether a physical activity program can help older women manage three common conditions together: an underactive thyroid, high eye pressure (glaucoma), and fatty liver disease. Researchers want to see if exercise improves symptoms and overall health when addressing multiple conditions at once.
Dokki, Giza GovernorateAges 65–75 - NCT07661329RecruitingPhase 3
Comparing a new eye drop to a standard one for glaucoma and high eye pressure
This study tests a new eye drop against an existing one to see which better lowers eye pressure in people with open-angle glaucoma or ocular hypertension. You may be able to join if you have high eye pressure in both eyes that needs treatment and you are at least 18 years old.
Beverly Hills, CaliforniaAges 18 years+ - NCT07662759RecruitingPhase 3
Study of TFC-003 for open-angle glaucoma or high eye pressure
This trial tests a new eye drop combination (TFC-003) to lower eye pressure in people with primary open-angle glaucoma or ocular hypertension. It compares the new drug to existing treatments to see if it works better or is safer.
SeongnamAges 19 years+
Hear when a new Primary Open Angle Glaucoma trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for primary open angle glaucoma?
- Yes. Clin2 currently lists 58 recruiting primary open angle glaucoma studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a primary open angle glaucoma trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a primary open angle glaucoma trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.