Clinical trials
Probiotic clinical trials
Below are recruiting probiotic clinical trials, each written for real people, not researchers. We’re tracking 225 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06514664Enrolling by invitation
Do probiotic toothpastes help gums and teeth?
This trial tests whether using a probiotic toothpaste can improve gum health in people with gum disease (periodontitis). It may help reduce inflammation and slow bone loss.
KütahyaAges 18–99 - NCT06422988Enrolling by invitation
Probiotics for preventing severe NEC in premature babies
This study looks at whether giving probiotics (good bacteria) to very premature babies (born before 32 weeks) can lower the risk of a serious gut problem called necrotizing enterocolitis (NEC). The researchers will review medical records of babies born between 2016 and 2022 in England and Wales.
LondonAges Up to 7 months - NCT06308497Enrolling by invitation
Periodontal treatment with CoQ10 and probiotics for pregnant women
This study tests whether a combination of coenzyme Q10 and probiotics can improve gum health in pregnant women. It aims to find a safe, gentle treatment for gum problems during pregnancy.
Pavia, LombardyAges 18–40 - NCT07758335RecruitingPhase 4
Probiotics and trace elements for ulcerative colitis
This trial tests whether adding a probiotic supplement and trace elements to your current treatment helps manage mild to moderate ulcerative colitis. It aims to see if these additions can improve symptoms and quality of life.
CairoAges 18–65 - NCT07508839Recruiting
Probiotic lozenge study for healthy adults
This trial tests a probiotic lozenge (a dissolvable tablet) to see if it's safe and works well. It's for healthy adults who don't smoke and are between 18 and 70 years old.
Hamilton, OntarioAges 18–70 - NCT07320287Recruiting
Probiotics for babies born by C-section
This trial tests whether a multi-strain probiotic supplement can help with growth, digestion, and gut health in healthy full-term babies who were born by C-section.
HanoiAges birth–1 day - NCT06873165Recruiting
Gut bacteria treatment for fatty liver disease
This study tests whether a specially designed gut bacteria treatment can help people with fatty liver disease and related health issues like high blood sugar, high cholesterol, or high blood pressure. It aims to see if the treatment is safe and improves liver health.
TaipeiAges 18–70 - NCT06817031Enrolling by invitationPhase 2
Probiotics for gut health in pregnancy – Bangladesh study
This study tests whether a daily probiotic capsule during pregnancy can improve the health of a mother's gut, especially if she is exposed to unclean water or poor sanitation. Pregnant women early in their second trimester who live in the Matlab area of Bangladesh may join.
ChāndpurAges 18 years+ - NCT07168772Recruiting
Probiotic supplement for multiple sclerosis
This study tests whether adding a probiotic supplement to your usual MS treatment (or to no treatment) can help manage relapsing-remitting multiple sclerosis. It aims to see if the probiotic is safe and beneficial as an add-on therapy.
Barcelona, BarcelonaAges 18–60 - NCT06936137RecruitingPhase 3
Probiotics for weight gain from antipsychotic medication
This trial tests if taking a probiotic supplement can help prevent or reduce weight gain caused by certain antipsychotic medications. It is for people with schizophrenia who have gained significant weight after starting these medications.
Cairo, AbbassiaAges 18–45 - NCT04527055Enrolling by invitationPhase 4
Bismuth treatment for H. pylori: 10 or 14 days
This trial compares two common stomach medicine plans that use bismuth for 10 days versus 14 days to clear an H. pylori infection. It may help you find a shorter or more effective treatment schedule if you have H. pylori confirmed by an endoscopy.
TainanAges 18–100 - NCT05427695RecruitingPhase 2
Probiotic rinse to treat chronic sinus inflammation
This Phase 2 study tests whether washing your sinuses with a probiotic solution can improve chronic sinusitis symptoms and inflammation. It’s for adults with chronic sinus symptoms that have flared, especially if you’ve had sinus surgery in the past.
Chicago, IllinoisAges 18 years+ - NCT06719596RecruitingPhase 1/Phase 2
Probiotics and nutrition after pancreas surgery
This trial tests whether taking probiotics with a special liquid nutrition feed after pancreatic surgery can lower the chance of getting an infection. If you are scheduled for this surgery, you may be able to join.
Nanjing, JiangsuAges 18 years+ - NCT07083596Recruiting
Fermented milk drink for constipation relief in Filipino adults
This study tests if a special fermented milk drink can help relieve constipation symptoms like hard or lumpy stools. Researchers want to see if it works for adults who have constipation without a known medical cause.
Manila, ManilaAges 18–59 - NCT06410443Recruiting
Steroid treatment for radiation-induced bowel injury
This trial tests if local steroids can help heal bowel damage caused by radiation therapy for cancer. It may reduce pain, bleeding, and urgency, and improve quality of life.
Shenyang, LiaoningAges 18 years+ - NCT07134790RecruitingPhase 2
Probiotics to improve gut health during pregnancy
This trial tests whether taking probiotics during pregnancy can improve gut health in mothers living in areas where gut infections are common. It is for women who are in their first or early second trimester and who have certain bacteria in their stool.
Bobo-DioulassoAges 18 years+ - NCT06981663Recruiting
Fibers and probiotics for uric acid levels
This study looks at how certain fibers and probiotics might affect uric acid levels in your body. You'll provide a stool sample, and it will be tested in a lab to see if these ingredients can help lower uric acid.
ÖrebroAges 18–80 - NCT07094984Recruiting
Clearing resistant gut bacteria: three FMT methods
This trial tests three different ways to clear antibiotic-resistant bacteria from your gut using fecal microbiota transplant (FMT). It may help if you have a confirmed resistant infection and are looking for a treatment to reduce the risk of future infections.
WarsawAges 18 years+ - NCT07415707Recruiting
Reducing alcohol and taking probiotics for brain health in older adults
This study tests whether cutting back on alcohol and taking probiotics can improve memory and thinking in older adults who are heavy drinkers. If you are interested in drinking less, you may be able to join.
Miami, FloridaAges 65–84 - NCT06802042Recruiting
Probiotic for constipation in pregnancy
This trial tests if a probiotic called Lactobacillus can help relieve constipation in pregnant women and improve gut health. It compares the probiotic to a placebo to see if it is safe and effective.
Beijing, Beijing MunicipalityAges 18–40 - NCT06446869Recruiting
Probiotic for menopause symptoms
This study tests whether a probiotic supplement can help reduce hot flashes and other menopause symptoms. It is for women who are in early menopause and have frequent hot flashes.
Glasgow, GlasgowAges 42–60 - NCT07207434RecruitingPhase 2
Probiotic supplement for pregnant women to improve gut health
This trial tests whether taking a probiotic during pregnancy can improve gut health in women living in areas where gut infections are common. It may help reduce harmful bacteria and related health problems for both you and your baby.
Matiari, SindhAges 18–49 - NCT07182942RecruitingPhase 4
Study of Xiqing and Probiotics for Chronic Kidney Disease
This trial tests if taking Xiqing (a Chinese herbal product) and probiotics together can help people with chronic kidney disease (CKD) by improving gut health and making their medication work better. It is for patients with moderate to advanced CKD who do not need dialysis yet.
Wuhan, HubeiAges 18–75 - NCT07268404Recruiting
Women's Hormonal and Metabolic Health Study
This trial tests a program to help women with irregular periods and hormonal imbalance symptoms like mood swings or skin issues. You'll track your symptoms and provide blood samples from home to see if the program improves your health.
San Francisco, CaliforniaAges 18–45
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Common questions
- Are there clinical trials for probiotic?
- Yes. Clin2 currently lists 225 recruiting probiotic studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a probiotic trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a probiotic trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.