Clinical trials
Probiotic clinical trials
Below are recruiting probiotic clinical trials, each written for real people, not researchers. We’re tracking 215 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05484128Recruiting
Probiotic for kids taking acid-reducing medicine
This trial studies whether a specific probiotic (Lactobacillus reuteri) is helpful for children who need acid-reducing medicine for reflux or stomach discomfort. It may help improve stomach symptoms while they are on or need treatment with proton pump inhibitors.
BariAges 1–14 - NCT06719596RecruitingPhase 1/Phase 2
Probiotics and nutrition after pancreas surgery
This trial tests whether taking probiotics with a special liquid nutrition feed after pancreatic surgery can lower the chance of getting an infection. If you are scheduled for this surgery, you may be able to join.
Nanjing, JiangsuAges 18 years+ - NCT07585474Enrolling by invitation
Gut Health During Long Travel for Football Players
This study looks at how long airplane trips affect the gut bacteria in professional male football players. Researchers will track changes in your digestive system during pre-season travel to understand if travel impacts your gut health.
Nashville, TennesseeAges 18–40 - NCT06729671Recruiting
Probiotics for antipsychotic-related metabolic issues
This trial tests if a probiotic supplement can help reduce metabolic side effects (like weight gain or high blood sugar) caused by antipsychotic medications. It is for people with psychosis who are on stable treatment.
CorkAges 18–65 - NCT06700044Recruiting
Probiotics for high-risk pregnancy
This study tests whether taking a probiotic supplement during pregnancy can help prevent complications in women at risk for preeclampsia. You would take a daily probiotic or placebo pill from about 20 weeks until delivery.
LundAges 18 years+ - NCT07539805RecruitingPhase 2
Sertraline Plus Probiotic for Teen Depression
This study tests whether combining sertraline (an antidepressant) with a specific probiotic called Lactobacillus crispatus can safely and effectively treat depression in teenagers. The probiotic may help by improving gut health, which researchers believe could support mental health.
Longgang, Chongqing MunicipalityAges 12–18 - NCT07531875Recruiting
Probiotics to Help Treat Advanced Gum Disease
This trial tests whether taking probiotics (beneficial bacteria) alongside standard gum disease treatment can help reduce deep pockets in your gums and improve healing. You'd be asked to take probiotics as an add-on to the care you're already receiving.
Kuala Lumpur, Kuala LumpurAges 18 years+ - NCT07517757Recruiting
Diet strategies for fibromyalgia in overweight women
This study tests whether specific eating plans can help reduce fibromyalgia symptoms (widespread pain and fatigue) in women who are overweight or obese. Fibromyalgia causes chronic body pain and tiredness, and this trial explores whether changing diet may improve how you feel.
Genova, GenovaAges 18–65 - NCT07508839Recruiting
Probiotic lozenge study for healthy adults
This trial tests a probiotic lozenge (a dissolvable tablet) to see if it's safe and works well. It's for healthy adults who don't smoke and are between 18 and 70 years old.
Hamilton, OntarioAges 18–70 - NCT07497932Recruiting
Nutritional effects in heart surgery
This trial looks at whether adding a probiotic supplement before cardiovascular surgery can improve recovery. It studies the link between nutrition, gut health, and surgical outcomes.
New Taipei CityAges 50–80 - NCT07490587RecruitingPhase 2
Probiotic study for healthy infant growth and allergy prevention
This trial tests a probiotic supplement (Bifidobacterium animalis subsp. lactis XLTG11) to see if it helps infants grow better and have fewer allergies. It is for healthy babies up to 3 years old who are at higher risk for allergies.
Pudong, Shanghai MunicipalityAges birth–3 years - NCT06802042Recruiting
Probiotic for constipation in pregnancy
This trial tests if a probiotic called Lactobacillus can help relieve constipation in pregnant women and improve gut health. It compares the probiotic to a placebo to see if it is safe and effective.
Beijing, Beijing MunicipalityAges 18–40 - NCT07429227Recruiting
Gut health and heart disease: a probiotic study
This trial tests whether natural extracts and probiotics can improve gut health in people who have had a recent heart attack (Acute Coronary Syndrome). It uses special exams to measure changes in gut bacteria.
Peschiera del Garda, VeronaAges 30–70 - NCT05524649Recruiting
Probiotics for healthy newborns’ poop bacteria balance
This study looks at whether giving probiotics to healthy newborns changes the bacteria in their stool. It may help researchers understand early gut health, but it is only for babies who meet specific health and timing requirements.
Alcaldía Coyoacán, PueblaAges 1 day–3 months - NCT07407894Recruiting
Probiotic study for healthy aging in midlife adults
This trial tests a probiotic supplement called iVS-1 to see if it can slow biological aging in healthy adults aged 40-75. Researchers want to learn if this probiotic may help support health as you age.
New Port Richey, FloridaAges 40–75 - NCT07413744RecruitingPhase 1
Gut health and probiotics study for memory concerns
This study looks at how a probiotic supplement affects the gut and thinking in older adults, including those with mild cognitive impairment or Alzheimer's. It may help explain if improving gut health can support brain health.
Madison, WisconsinAges 60 years+ - NCT07415707Recruiting
Reducing alcohol and taking probiotics for brain health in older adults
This study tests whether cutting back on alcohol and taking probiotics can improve memory and thinking in older adults who are heavy drinkers. If you are interested in drinking less, you may be able to join.
Miami, FloridaAges 65–84 - NCT07383441RecruitingPhase 3
Adding Biotherapy or Placebo to Standard Kidney Cancer Treatment
This trial tests whether adding a biotherapy (a special drug from a living source) or a placebo to standard treatments helps people with advanced kidney cancer. It may be a good option if your cancer hasn't been treated yet and you are in fairly good health.
Fayetteville, ArkansasAges 18 years+ - NCT07383701RecruitingPhase 2
Probiotic for diabetic macular edema
This trial tests whether a daily probiotic supplement (Lactiplantibacillus plantarum 299v) can help improve diabetic macular edema, a swelling in the back of the eye caused by diabetes. The goal is to see if adding this probiotic to your regular care could reduce swelling and protect your vision.
Boston, MassachusettsAges 18 years+ - NCT07377994Enrolling by invitation
Gut health and immunity study with a probiotic in healthy adults
This trial tests a probiotic supplement containing Bacillus coagulans to see if it improves gut health and immune function in healthy adults. If you are generally healthy and not taking certain medications or supplements, you may be able to join.
Bangalore, KarnatakaAges 18–50 - NCT07377942Enrolling by invitation
Probiotic study for gut and immune health in healthy adults
This study tests a probiotic (a type of good bacteria) called Bacillus subtilis to see how it affects digestion and the immune system in healthy adults. It involves taking the product, giving stool samples, and visiting the clinic for checkups.
Bangalore, KarnatakaAges 18–50 - NCT07369830Recruiting
Probiotics for bowel function after rectal cancer surgery
This trial tests whether taking a probiotic supplement (Clostridium butyricum) can improve gut health and bowel function after surgery for very low rectal cancer. It may help patients who have a temporary ileostomy and are planning to have it reversed within 6 months.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06211062RecruitingPhase 2
Probiotics for chronic fatigue syndrome with IBS
This study tests whether a specific mix of probiotics can help people with chronic fatigue syndrome (ME/CFS) who also have irritable bowel syndrome (IBS). It's a small trial to see if improving gut health can ease symptoms.
Fort Lauderdale, FloridaAges 45–70 - NCT07341750Recruiting
Probiotic study for immune health in school-aged children
This trial tests whether a probiotic called Bacillus Coagulans SNZ 1969 can support the immune health of healthy children aged 6 to 12. Your child would take the probiotic or a placebo daily for a period while keeping their usual routine.
London, OntarioAges 6–12
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Common questions
- Are there clinical trials for probiotic?
- Yes. Clin2 currently lists 215 recruiting probiotic studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a probiotic trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a probiotic trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.