Clinical trials
Probiotic clinical trials
Below are recruiting probiotic clinical trials, each written for real people, not researchers. We’re tracking 225 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07293910RecruitingPhase 2
Comparing treatments for H. pylori infection
This trial tests whether a new type of acid-reducing drug (vonoprazan) works better than a common one (proton pump inhibitor) when combined with vitamin D or probiotics to clear H. pylori, a bacteria that can cause stomach problems. If you have H. pylori and haven't been treated for it before, this study may be for you.
TantaAges 18–80 - NCT07297966RecruitingPhase 2
Probiotics for recurrent respiratory infections in children
This trial tests if a daily probiotic can help young children who get frequent respiratory infections like colds and coughs. It aims to see if the probiotic reduces how often infections happen.
Xingyi, GuangdongAges 1 day–6 years - NCT07304505Recruiting
Probiotics for adults with rheumatoid arthritis
This study tests whether a daily probiotic supplement can help adults with rheumatoid arthritis. You must have a stable RA treatment plan and be willing to take the probiotic for the duration of the study.
Chicago, IllinoisAges 18 years+ - NCT07341087Recruiting
Probiotic drink study for skin inflammation in menopause
This study tests whether a daily probiotic drink can improve inflammatory skin conditions like rosacea, acne, or eczema in women aged 40 to 60. You will take the drink for 8 weeks and provide blood, skin, stool samples, and a photo of your face.
London, LondonAges 40–60 - NCT07345455Recruiting
Probiotics for improving sperm quality in male infertility
This trial tests whether taking probiotics can improve sperm quality in men with unexplained infertility. It may help if you have low sperm count, low motility, or abnormal shape.
New Taipei CityAges 20–45 - NCT07347743Recruiting
Probiotic supplement for crying and colic in healthy newborns
This trial tests whether a daily probiotic supplement can reduce excessive crying and colic in healthy, full-term newborns. If your baby is healthy and born at UZ Brussel, this study may help find a gentle way to soothe colic.
Jette, Brussels CapitalAges 1 day–2 weeks - NCT07362251Recruiting
Testing a probiotic supplement in healthy adults
This study is testing a multi-strain probiotic supplement (Smile Probio 45B) to see how well healthy adults tolerate it. You may be able to join if you are generally healthy, not taking antibiotics or other probiotics, and within a normal weight range.
Trikala, ThessalyAges 18 years+ - NCT06051123Recruiting
Probiotics for ALS and related disorders
This trial tests whether probiotics (healthy bacteria) can help people with ALS. You'll take a probiotic or placebo daily for several months, and researchers will track your symptoms and gut health.
Fredericton, New BrunswickAges 18 years+ - NCT07533890Recruiting
Probiotics and gut health in children with inflammatory bowel disease
This study tests whether a multi-strain probiotic supplement can change the gut bacteria in children and teens with inflammatory bowel disease (IBD). Researchers will collect stool samples to see if the probiotics help restore healthy gut bacteria and potentially improve symptoms.
BernAges 5–18 - NCT07400367Recruiting
Probiotics and lifestyle changes for fatty liver disease
This trial tests whether taking probiotics plus making lifestyle changes can improve fatty liver and metabolic health. You may qualify if you have liver fat and at least one sign of metabolic problems like high blood sugar or high blood pressure.
New Taipei CityAges 18–80 - NCT07443410Recruiting
Probiotics for gum disease treatment
This trial tests whether taking pre- and probiotics alongside non-surgical gum treatment improves healing and reduces harmful bacteria. It may help people with advanced gum disease (stage III or IV periodontitis).
Heidelberg, Baden-WurttembergAges 18 years+ - NCT07331987Recruiting
Probiotics for mild to moderate anxiety or depression study
This trial tests if probiotics can help reduce symptoms of mild to moderate anxiety or depression. It is for people aged 18–60 who are not currently taking most anxiety or depression medications and who have not used them in the last 2 weeks (except for escitalopram).
Guangzhou, GuangdongAges 18–60 - NCT07584278Recruiting
Probiotics and Biomarkers for Irritable Bowel Syndrome
This study tests whether probiotics (beneficial bacteria) can help reduce irritable bowel syndrome (IBS) symptoms and change certain markers in your gut. You'll take a probiotic supplement for 12 weeks while researchers track how your symptoms and gut health change.
GothenburgAges 18 years+ - NCT07585994Recruiting
Probiotic supplement for long-standing type 1 diabetes
This study tests whether taking a specific probiotic (a beneficial bacteria) for 4 weeks can improve immune function and metabolism in people who have had type 1 diabetes for at least 5 years. Researchers believe this probiotic may help the body's remaining insulin-producing cells work better.
AmsterdamAges 18 years+ - NCT07605728RecruitingPhase 2
Probiotics to ease stomach problems from breast cancer treatment
This trial tests whether a special probiotic supplement (good bacteria) can reduce belly discomfort caused by abemaciclib, a hormone therapy drug for early breast cancer. You would take the supplement alongside your cancer treatment to see if it helps with stomach side effects.
TaipeiAges 18 years+ - NCT07606014RecruitingPhase 2/Phase 3
Probiotics to Support Mental Health Treatment
This study tests whether taking special probiotics (beneficial bacteria) can help prevent weight gain and metabolic changes when starting antipsychotic medications for psychosis. You'd take probiotics daily while beginning or recently starting one of four common antipsychotic drugs.
Leeuwarden, Provincie FrieslandAges 18–65 - NCT07619560Recruiting
Probiotic Cocktail to Slow Early Parkinson's Disease
This study tests whether a special blend of probiotics (good bacteria), an amino acid called tryptophan, and branched-chain amino acids can help slow the progression of early-stage Parkinson's disease. The idea is that these supplements may work through your gut bacteria to help protect your brain.
TaipeiAges 30–85 - NCT07645157RecruitingPhase 2
Sertraline and Probiotics for Teen Depression
This study tests whether combining an antidepressant medication (sertraline) with special bacteria supplements (probiotics) can help treat depression in teenagers ages 12–18. Researchers believe the probiotics may help the medication work better by improving gut health.
Chongqing, YuzhongAges 12–18 - NCT07253155Enrolling by invitation
Probiotics for preventing gut symptoms in overweight adults
This study tests whether taking probiotics can help prevent stomach and gut discomfort in people who are overweight or have obesity. You may be eligible if you are at a certain weight and age, eat a balanced diet, and do not have chronic gut issues.
ColeraineAges 18 years+ - NCT07164781Enrolling by invitation
Probiotics for preventing infections in ICU patients
This trial tests whether probiotics (good bacteria) can help prevent serious infections in critically ill patients in the ICU. If you are very sick and in the ICU, you may be able to join — as long as you don't have certain conditions like cancer or a weakened immune system.
Banhā, Qalyubia GovernorateAges 18 years+ - NCT07114133Enrolling by invitation
Environmental probiotics for cat hair allergies
This study tests whether a special probiotic spray, used in your home, can reduce allergy symptoms in people who are allergic to cats. If you have cat allergies with nasal symptoms and live in a stable home, you may be able to join.
Hangzhou, ZhejiangAges 18–70 - NCT06722443Enrolling by invitation
Probiotics and Prebiotics for Obesity
This trial tests whether adding probiotics and prebiotics to your diet can help with obesity and related health problems like prediabetes, diabetes, high cholesterol, or high blood pressure.
Granada, SpainAges 18–75 - NCT06636669Enrolling by invitationPhase 4
Probiotics to prevent repeat joint infection after replacement surgery
This trial tests whether taking probiotics can help prevent another infection in people who have had a hip or knee replacement that became infected. If you are scheduled for revision surgery due to an infection, this study may be a good fit.
Boston, MassachusettsAges 18–90 - NCT06560879Enrolling by invitationPhase 2
Probiotics to prevent stomach problems in children with leukemia
This trial tests whether probiotics can help prevent stomach and gut side effects from chemotherapy in children with leukemia. If your child is between 6 and 17, in the right phase of treatment, and doesn't have any major gut issues, they may be eligible.
Mexico City, CoyoacanAges 6–17
Hear when a new Probiotic trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for probiotic?
- Yes. Clin2 currently lists 225 recruiting probiotic studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a probiotic trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a probiotic trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.