Clinical trials
Progression clinical trials
Below are recruiting progression clinical trials, each written for real people, not researchers. We’re tracking 711 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT02964637Recruiting
Tests to help diagnose frontotemporal dementia
This study looks at testing (including brain scans) to figure out what type of frontotemporal dementia or related language/speech condition a person has. It may help by making diagnoses more accurate, which can guide better care.
Toronto, OntarioAges 18–90 - NCT07222618Recruiting
Selfie videos to measure function in MS
This trial asks people with MS to record short 'selfie' videos of themselves doing everyday tasks, like walking or getting dressed. The goal is to find a better, more personal way to measure how MS affects daily function.
San Francisco, CaliforniaAges 18 years+ - NCT07225504RecruitingPhase 3
Study of remibrutinib for secondary progressive multiple sclerosis
This trial tests an oral medication called remibrutinib to see if it can slow disability progression in people with secondary progressive multiple sclerosis (SPMS). You might join if you have had MS for a while, your symptoms have worsened over the past year, and you haven't had any recent relapses.
Birmingham, AlabamaAges 18–65 - NCT06913933Recruiting
Comparing two splints for wrist stiffness after a broken wrist
This study compares two types of splints (one that stays still and one that lets you move a little) to help people regain wrist motion after a broken wrist has healed. It may test whether a dynamic splint works better than a static one for persistent stiffness.
CairoAges 18–65 - NCT07217665Enrolling by invitationPhase 2
AADvac1 vaccine for progressive supranuclear palsy
This trial tests a vaccine called AADvac1 for people with progressive supranuclear palsy (PSP), a brain condition that affects movement and thinking. The study wants to see if the vaccine can slow the disease down.
San Francisco, CaliforniaAges 41–86 - NCT06450470RecruitingPhase 3
Amniotic membrane after crosslinking for progressive keratoconus
This trial tests if placing a special freeze-dried amniotic membrane on the eye after crosslinking surgery helps improve healing and comfort for people with progressive keratoconus, a condition where the cornea thins and bulges.
BrestAges 18–65 - NCT07206056RecruitingPhase 1/Phase 2
Study of tulmimetostat and luxdegalutamide for advanced prostate cancer
This trial tests a new combination of two drugs for men whose prostate cancer has spread and is no longer controlled by hormone therapy. The study aims to see if this treatment can help shrink tumors or slow the disease.
Denver, ColoradoAges 18 years+ - NCT06306170Recruiting
Advanced radiation for gynecologic cancer
This trial is for people with gynecologic cancer who will receive modern, targeted radiation therapy. It aims to see how well these advanced treatments work and how patients feel during and after therapy.
Milan, MIAges 18–90 - NCT07185919Recruiting
Odevixibat (Bylvay) study for PFIC patients in South Korea
This study is tracking how well odevixibat (Bylvay) works and how safe it is for people with progressive familial intrahepatic cholestasis (PFIC) in South Korea. It is for patients who are already prescribed this medicine by their doctor, and it monitors their progress over time.
GyeongsangAges Any age - NCT07173803RecruitingPhase 2
PSP clinical trial testing new treatments
This trial tests potential new treatments for progressive supranuclear palsy (PSP), a brain disorder affecting movement, balance, and thinking. It aims to see if these treatments are safe and slow the disease. You may be able to join if you have a specific type of PSP and are in fairly good health.
Sun City, ArizonaAges 41–86 - NCT07139743RecruitingPhase 1
Obe-cel for progressive multiple sclerosis that is getting worse
This study tests a new treatment called obe-cel, a type of CAR T-cell therapy, for people with progressive multiple sclerosis that hasn't responded to other treatments. It aims to see if this therapy can slow or stop the disease from getting worse.
Redwood City, CaliforniaAges 18–60 - NCT07136844Recruiting
Walking and arm movement study for nerve and muscle conditions
This study uses motion analysis to understand walking and arm function in adults with certain neurological or metabolic diseases. The goal is to find patterns that help doctors better manage these conditions.
LiègeAges 18 years+ - NCT07117981Recruiting
Study of second-line treatment for thyroid eye disease
This trial looks at how thyroid eye disease (inflammation behind the eyes) changes over time in people who need stronger treatments after steroids haven't worked well enough. It aims to better understand the disease and how different second-line treatments may help.
Paris, parisAges 18 years+ - NCT07098390Recruiting
Relaxation to Reduce Fear and Pain After Joint Replacement
This study tests whether a simple relaxation technique (progressive muscle relaxation) can help reduce fear of falling, pain, and anxiety after hip or knee replacement surgery. It may be a safe, drug-free way to feel better during recovery.
AnkaraAges 18 years+ - NCT07076472RecruitingEarly Phase 1
Sound and drug therapy for recurrent glioblastoma
This trial tests a new approach that combines a drug (SONALA-001 or 5-ALA) with focused ultrasound to treat glioblastoma that has come back or is growing despite standard treatments. The drug makes tumor cells sensitive to sound waves, and the ultrasound waves are directed at the tumor using MRI guidance. This may help damage cancer cells while sparing healthy brain tissue.
Rochester, MinnesotaAges 18 years+ - NCT07085676RecruitingPhase 1
CAR-T cell therapy for autoimmune diseases that resist treatment
This study tests a new cell therapy called CAR-T (using your own immune cells) for people with severe autoimmune diseases like lupus, scleroderma, or myositis that have not improved with standard treatments. The goal is to see if it can safely reduce disease activity.
JerusalemAges 18–80 - NCT07067463RecruitingPhase 3
Testing orelabrutinib for primary progressive MS
This trial tests a daily pill called orelabrutinib to see if it can slow disability progression in people with primary progressive multiple sclerosis (PPMS). It may be an option for patients whose symptoms have been getting worse over the past two years.
Pheonix, ArizonaAges 18–60 - NCT06337357Recruiting
Strength training for older adults with diabetes and muscle loss
This trial tests whether a specific strength-training program (called progressive resistance training) can help older adults with both type 2 diabetes and sarcopenia (muscle loss) improve muscle strength and overall function.
HanoiAges 60–80 - NCT07061379Recruiting
Patient feedback in first-line lung cancer treatment study
This study collects patient feedback through questionnaires to see if it helps improve outcomes for people with advanced non-small-cell lung cancer starting chemo-immunotherapy. It may help your care team better understand how you are feeling.
Milan, ItalyAges 18 years+ - NCT04468932Recruiting
TMS brain stimulation for progressive supranuclear palsy
This trial tests whether repeated non-invasive magnetic brain stimulation (TMS) can improve symptoms in people with progressive supranuclear palsy (PSP). It may help by targeting brain circuits involved in movement and balance.
Portland, OregonAges 40–85 - NCT06890923RecruitingPhase 2
Nasal foralumab for non-active secondary progressive MS
This trial tests a nasal spray medication, foralumab, to see if it can help people with non-active secondary progressive multiple sclerosis. It is only for people who completed a previous related study (TILS-021).
Boston, MassachusettsAges 18–75 - NCT06960408Enrolling by invitation
Sleep, relaxation, and diabetes: A study on reducing anxiety
This study tests whether learning about good sleep habits and practicing a simple relaxation technique can help people with diabetes sleep better, feel less anxious, and improve blood sugar control.
AnkaraAges 18–64 - NCT06924164Recruiting
Strength training for snapping hip syndrome
This trial tests if progressive strength training can reduce pain and snapping in adults with external snapping hip. If you have a snapping or popping sensation on the outside of your hip with discomfort, this study may help find a non-surgical treatment option.
AalborgAges 18–40 - NCT06900777Recruiting
Comparing two treatments for rapidly spreading vitiligo in children
This trial compares two medicines—oral tacrolimus and dexamethasone micro-pulse therapy—in children aged 4 to 12 whose vitiligo is spreading quickly. The goal is to see which treatment works better to stop the spread and help color return to the skin.
Xi'an, ShaanxiAges 4–12
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Common questions
- Are there clinical trials for progression?
- Yes. Clin2 currently lists 711 recruiting progression studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a progression trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a progression trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.