Clinical trials
Progression clinical trials
Below are recruiting progression clinical trials, each written for real people, not researchers. We’re tracking 719 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05811013Recruiting
Static magnetic brain stimulation for progressive multiple sclerosis
This trial studies whether a noninvasive brain stimulation approach using a static magnetic field can help people with progressive multiple sclerosis. It aims to improve progressive nerve function while keeping other treatments stable.
Pozzilli, IserniaAges 18–65 - NCT05849467RecruitingPhase 1
Testing how the brain absorbs anti–CD8 therapy in nervous system disease
This Phase 1 study tests a small drug (called an anti–CD8+ T cell minibody) to see how much reaches the brain. It may help researchers understand how to deliver similar treatments for multiple sclerosis, progressive multifocal leukoencephalopathy (PML), or other brain inflammation when the brain’s protective barrier is “open.”
Bethesda, MarylandAges 18–120 - NCT05904119RecruitingPhase 3
Lomustine with or without re-irradiation for recurring glioblastoma
This trial studies whether adding repeat radiation (called re-irradiation) to the chemotherapy medicine lomustine can slow or control glioblastoma that has returned or progressed after standard treatment. It’s designed for people whose tumor comes back at least 6 months after their last radiation.
InnsbruckAges 18 years+ - NCT05939362Recruiting
7T MRI imaging study to predict Alzheimer’s progression
This study uses very high-strength MRI scans (7T) to look for brain imaging patterns that may predict how Alzheimer’s disease will progress. It may help doctors spot which changes are linked to faster or slower decline.
PoitiersAges 60–90 - NCT05961644RecruitingPhase 2/Phase 3
Cladribine vs placebo for non-active progressive multiple sclerosis
This trial tests whether cladribine (vs an inactive placebo pill) can slow disability worsening in people with a non-active, progressive form of multiple sclerosis. It may help by reducing the immune activity that can drive ongoing nerve damage, even without recent relapses.
Warsaw, Masovian VoivodeshipAges 30–65 - NCT05966038Recruiting
Study of ALS and related movement nerve conditions
This study collects and stores medical information from people diagnosed with ALS or certain related conditions affecting movement. It may help researchers better understand how these illnesses change over time and improve future treatments.
Loma Linda, CaliforniaAges 18–90 - NCT06066710RecruitingEarly Phase 1
Propranolol for Primary Progressive Aphasia
This trial tests whether the drug propranolol, often used for high blood pressure, can help people with primary progressive aphasia (a condition that slowly affects language skills). You would take the drug and have MRI brain scans to see if it slows language decline.
Columbia, MissouriAges 50 years+ - NCT06079463Recruiting
Relaxation exercise for anxiety and quality of life in diabetes
This study tests whether a simple, step-by-step muscle relaxation exercise can help reduce anxiety and improve quality of life for adults with diabetes who are in the hospital for treatment.
ErzurumAges 18 years+ - NCT06148818Recruiting
Neck exercises for jaw pain relief
This study tests whether special neck exercises can help reduce jaw pain in people who have both jaw (TMJ) problems and neck pain. If you have had jaw pain for at least 3 months and also have achy neck pain, you may be able to join.
TrabzonAges 18–55 - NCT06161402Recruiting
Elastic band exercise for muscle loss in heart failure patients
This trial tests whether a simple at-home exercise program using elastic bands can help older adults with heart failure who also have muscle weakness or low muscle mass (sarcopenia). The goal is to improve strength and daily function.
Hong KongAges 50 years+ - NCT06306170Recruiting
Advanced radiation for gynecologic cancer
This trial is for people with gynecologic cancer who will receive modern, targeted radiation therapy. It aims to see how well these advanced treatments work and how patients feel during and after therapy.
Milan, MIAges 18–90 - NCT07511049RecruitingPhase 2
Brincidofovir for PML brain infection
This pilot study tests an IV medicine called brincidofovir for people with PML, a serious brain infection. The goal is to see if it can stop the virus from causing more damage.
Bethesda, MarylandAges 18–99 - NCT06337357Recruiting
Strength training for older adults with diabetes and muscle loss
This trial tests whether a specific strength-training program (called progressive resistance training) can help older adults with both type 2 diabetes and sarcopenia (muscle loss) improve muscle strength and overall function.
HanoiAges 60–80 - NCT06460636Recruiting
Water therapy and relaxation for fibromyalgia pain
This trial tests if combining relaxation exercises with water therapy can help reduce fibromyalgia pain and symptoms. It is for women aged 20 to 39 who are married and have a confirmed fibromyalgia diagnosis.
Rahim Yar Khan, Punjab ProvinceAges 20–39 - NCT06460649Recruiting
Relaxation techniques for new mothers: a study
This study tests whether combining two relaxation methods (Benson and progressive relaxation) can help new mothers feel calmer and recover better. It's for women who are 2 weeks to 6 months postpartum and in good general health.
Lahore, Punjab ProvinceAges 20–40 - NCT06473714Recruiting
Brain stimulation for language in progressive aphasia
This trial tests a gentle, non-invasive brain stimulation called tDCS to see if it can help improve language control in people with primary progressive aphasia. It is done in a hospital in Nice, France.
NiceAges 18 years+ - NCT07691697Recruiting
PSMA PET-guided radiation for slowing prostate cancer growth
This trial uses a special scan called PSMA PET to find and treat a small number of cancer spots that are growing while you are on standard treatment. The goal is to give precise radiation to those spots to help keep the rest of the cancer under control.
Zamość, Lublin VoivodeshipAges 18 years+ - NCT06526364Recruiting
Multiple sclerosis study with smartphone app tracking
This study follows people with multiple sclerosis over time using a smartphone app and clinic visits. It aims to better understand the disease and improve care.
BaselAges 18 years+ - NCT06529744Recruiting
Using blood tests to better diagnose early dementia
This study is testing whether simple blood tests can help doctors better understand the type and progression of memory or thinking problems in people with early dementia. It aims to improve confidence in the diagnosis and future outlook.
North York, OntarioAges 30–95 - NCT06536764Recruiting
Relaxation exercises for pregnancy back pain
This trial tests whether progressive muscle relaxation exercises can help reduce low back pain and improve sleep quality during pregnancy. It may be helpful if you are in your second or third trimester, have uncomplicated pregnancy, and are experiencing moderate to severe back pain and poor sleep.
Mirpur, Azad Jammu & KashmirAges 20–40 - NCT06596746Recruiting
Tracking markers for neurodegenerative diseases
This study tracks changes in people with Parkinson's disease, other movement disorders, or cognitive decline to find better ways to measure disease progression.
Cassino, FrosinoneAges 10 years+ - NCT06599307RecruitingPhase 2
Rituximab for thinking and hand function in advanced MS
This trial tests whether the drug rituximab can help people with secondary progressive MS keep their thinking and hand abilities from getting worse. It is for people with more advanced disability.
Giza, Giza GovernorateAges 18 years+ - NCT06614309Recruiting
Non-invasive treatment for brain fog from long COVID
This study tests a non-invasive treatment to help with brain fog caused by long COVID. It may improve your symptoms if you have trouble thinking clearly or focusing.
Scottsdale, ArizonaAges 18 years+ - NCT06640166RecruitingPhase 2
Encorafenib + Cetuximab with FOLFIRI after progression
This trial tests adding a new chemotherapy regimen (FOLFIRI) to the combination of Encorafenib and Cetuximab for people with a specific type of advanced colorectal cancer that has started growing again after initial treatment with Encorafenib and Cetuximab. The goal is to see if the new combination can help control the cancer longer.
MilanAges 18 years+
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Common questions
- Are there clinical trials for progression?
- Yes. Clin2 currently lists 719 recruiting progression studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a progression trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a progression trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.