Clinical trials
Progression clinical trials
Below are recruiting progression clinical trials, each written for real people, not researchers. We’re tracking 716 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07588880Recruiting
Tracking Odevixibat Safety and Outcomes in PFIC Patients
This study follows patients with PFIC (a rare liver disease affecting bile flow) who are taking or planning to take odevixibat (Bylvay), a medication that helps manage the condition. Researchers will track how well the medication works, any side effects, and long-term health outcomes in Chinese patients.
BeijingAges 6 months+ - NCT07587125RecruitingPhase 1
CAR-T Cell Therapy for Progressive Multiple Sclerosis
This trial tests a new cell therapy called S103 for people with MS that isn't responding well to standard treatments. The therapy involves modifying immune cells in the lab and putting them back into your body to help control the disease.
Xi'an, ShaanxiAges 18–75 - NCT07576218Recruiting
Pilates and prone plank exercises for postpartum abdominal separation
This study tests whether Pilates and specific core exercises can help close the gap between abdominal muscles (called diastasis recti) that commonly happens after pregnancy. Diastasis recti can cause weakness and discomfort, and this trial evaluates whether these exercises improve that condition.
Lahore, Punjab ProvinceAges 18–45 - NCT05177523Recruiting
MRI study of nerve damage and repair in multiple sclerosis
This trial uses MRI scans to better understand how nerve fibers are damaged and repaired in people with multiple sclerosis. It may help researchers connect scan findings to disease activity and progression.
BaselAges 18–80 - NCT07567664Enrolling by invitation
Brain Changes in Neurodegenerative Diseases: A Tracking Study
This research study tracks how brain damage progresses in rare neurodegenerative diseases like frontotemporal dementia, primary progressive aphasia, PSP, CBS, and ALS. Researchers use brain imaging and tests to understand how these diseases spread in the brain, which could help develop better treatments.
Milan, LombardyAges 20–85 - NCT06708156RecruitingPhase 3
Low-dose atropine drops to slow childhood nearsightedness
This trial tests two low-dose atropine eye drops (0.01% and 0.02%) to see if they can safely slow down the worsening of nearsightedness (myopia) in children. Your child would receive either one of these drops or a placebo (an inactive drop) once daily for up to 2 years.
Hefei, AnhuiAges 6–12 - NCT07511049RecruitingPhase 2
Brincidofovir for PML brain infection
This pilot study tests an IV medicine called brincidofovir for people with PML, a serious brain infection. The goal is to see if it can stop the virus from causing more damage.
Bethesda, MarylandAges 18–99 - NCT07512895Recruiting
Muscle Relaxation Exercises for Depression and Fatigue in Dialysis Patients
This study tests whether guided muscle relaxation exercises can reduce depression and tiredness in people undergoing hemodialysis (a blood-filtering treatment). You would learn and practice simple exercises to relax your muscles, which may help improve your mood and energy.
Istanbul, IstanbulAges 18–75 - NCT07462897Recruiting
New lens to slow nearsightedness in children
This trial tests a special eyeglass lens designed to slow down the worsening of nearsightedness (myopia) in children ages 6 to 14. It aims to keep their eyesight from getting worse quickly.
ParisAges 6–14 - NCT06778174Recruiting
Treating progressive familial intrahepatic cholestasis
This study tracks treatments and outcomes for people with a confirmed genetic form of PFIC, a rare liver disease. It helps doctors learn which treatments work best for each type.
GroningenAges Any age - NCT06148818Recruiting
Neck exercises for jaw pain relief
This study tests whether special neck exercises can help reduce jaw pain in people who have both jaw (TMJ) problems and neck pain. If you have had jaw pain for at least 3 months and also have achy neck pain, you may be able to join.
TrabzonAges 18–55 - NCT07426991Recruiting
Multiple sclerosis, thinking, sleep, and tiredness study
This study looks at how multiple sclerosis (MS) affects your thinking, sleep, and tiredness. It compares people with MS who have at least mild fatigue to people without MS who also have sleep problems, to understand these issues better.
DüsseldorfAges 18–79 - NCT06640166RecruitingPhase 2
Encorafenib + Cetuximab with FOLFIRI after progression
This trial tests adding a new chemotherapy regimen (FOLFIRI) to the combination of Encorafenib and Cetuximab for people with a specific type of advanced colorectal cancer that has started growing again after initial treatment with Encorafenib and Cetuximab. The goal is to see if the new combination can help control the cancer longer.
MilanAges 18 years+ - NCT07387159Recruiting
Studying MiYOSMART lenses to slow nearsightedness in kids
This trial tests whether special MiYOSMART iQ spectacle lenses can slow down worsening nearsightedness (myopia) in children. It aims to find a safe, non-invasive way to help kids see clearly longer.
MoscowAges 8–11 - NCT07362225Recruiting
MPN Progress Registry: Tracking Symptoms and Progression
This observational registry tracks symptoms, treatments, and disease changes over time in people diagnosed with myeloproliferative neoplasms (MPNs). By joining, you help doctors learn more about the condition and possibly contribute to better future care.
Chicago, IllinoisAges 18 years+ - NCT07361705RecruitingPhase 1
Zorifertinib and osimertinib for lung cancer that spread to the brain lining
This trial tests a new drug, zorifertinib, combined with osimertinib for people whose lung cancer has spread to the lining of the brain (meninges) and continued to grow despite osimertinib treatment. The goal is to see if this combination can better control the brain spread.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06536764Recruiting
Relaxation exercises for pregnancy back pain
This trial tests whether progressive muscle relaxation exercises can help reduce low back pain and improve sleep quality during pregnancy. It may be helpful if you are in your second or third trimester, have uncomplicated pregnancy, and are experiencing moderate to severe back pain and poor sleep.
Mirpur, Azad Jammu & KashmirAges 20–40 - NCT07342777Recruiting
Exercise for Pain Relief in Multiple Sclerosis
This study tests whether exercise can help reduce pain in people with multiple sclerosis. If you have MS and moderate to severe pain, you may be asked to participate in a supervised exercise program.
Aarhus, DenmarkAges 18 years+ - NCT07311694RecruitingPhase 3
Comparing a new treatment with standard drugs for advanced prostate cancer
This trial tests a new drug, HRS-4357, against standard treatments for men with a specific type of advanced prostate cancer that has spread and no longer responds to hormone therapy. It aims to see if the new drug works better.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06660056RecruitingPhase 1
GC001 injection for returning or growing high-grade brain tumors
This trial tests a new drug, GC001, injected directly into the tumor in people with high-grade gliomas (WHO grade 3 or 4) that have come back or are growing. It may be an option if standard treatments have stopped working.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07299019RecruitingPhase 3
Study of orelabrutinib for secondary progressive MS
This study tests an oral medication called orelabrutinib for people whose multiple sclerosis has changed from relapsing-remitting to secondary progressive. The goal is to see if it can slow down disability worsening that happens even without relapses.
Phoenix, ArizonaAges 18–60 - NCT07290257RecruitingPhase 4
Long-term safety study of Livmarli for Alagille syndrome or PFIC
This study looks at the long-term safety and effects of Livmarli (maralixibat) in children with Alagille syndrome or progressive familial intrahepatic cholestasis (PFIC). It may help understand how well the medicine works over time for itching and other symptoms.
BrusselsAges 2 months+ - NCT07293897Recruiting
Study of Livmarli for Alagille Syndrome and PFIC
This study looks at how well Livmarli works for people with Alagille syndrome or a liver disease called PFIC. It uses data from prescriptions to understand the treatment's effects.
Tokyo, TokyoAges Any age - NCT07282574RecruitingPhase 2
Study of an add-on drug for progressive multiple sclerosis
This trial tests whether adding a new medication, RO7268489, to the standard treatment ocrelizumab (Ocrevus) can help people with progressive forms of multiple sclerosis (MS) by slowing disability progression. The trial will evaluate the safety and effectiveness of this combination approach.
Camperdown, New South WalesAges 18–60
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Common questions
- Are there clinical trials for progression?
- Yes. Clin2 currently lists 716 recruiting progression studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a progression trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a progression trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.