Clinical trials
Prostate cancer clinical trials
Cancer of the prostate gland, one of the most common cancers in men. We’re tracking 1,219 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03920033Recruiting
Radiation schedule for prostate cancer PSA relapse after surgery
This trial compares two different radiation schedules to treat prostate cancer that returned based on rising PSA blood tests after prostatectomy (prostate removal). If you qualify, it may help you and your team choose a radiation approach with the goal of controlling PSA relapse.
SeoulAges 20 years+ - NCT05568550RecruitingPhase 2
Radiation with or without olaparib for high-risk prostate cancer
This Phase 2 study tests whether adding a medicine called olaparib to radiation helps men with high-risk prostate cancer. You may receive radiation alone or radiation plus olaparib, and the study looks at whether the combination works better.
Lexington, KentuckyAges 18 years+ - NCT04100174RecruitingPhase 2
HDR radiation boost for prostate cancer during standard treatment
This study tests adding a targeted “boost” of HDR (high-dose-rate) internal radiation to the prostate along with standard external beam radiation. It may help improve cancer control while keeping the treatment focused on the area seen on scans and biopsy.
Montreal, QuebecAges Any age - NCT04186585RecruitingPhase 1
Testing the safest dose for a prostate cancer drug
This early-phase trial (Phase 1) tests the safest dose of BP-C2 in people with prostate cancer who are on hormone treatment. It’s mainly designed to check safety and how the body handles the medicine, which could help future treatment options.
Skjetten, AkershusAges 18–80 - NCT04242017RecruitingPhase 2/Phase 3
Longer hormone treatment plus salvage radiation versus shorter
This trial compares two schedules of hormone treatment (ADT) along with salvage radiation after prostate cancer surgery, to see which one controls cancer better over the long term. It may help people who have a rising PSA level after surgery but no spread found yet.
GhentAges Any age - NCT04271527Recruiting
Compare two prostate biopsy guidance methods in men with PSA rise
This trial tests whether using a “cognitive” approach versus a software-guided approach to plan a prostate biopsy is just as effective. It may help improve how biopsies are targeted for men with PSA changes and/or abnormal prostate exams.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT04638088Recruiting
Robot or standard surgery for prostate removal
This trial compares different ways of doing a radical prostatectomy (surgery to remove the prostate): robot-assisted laparoscopy, conventional laparoscopy, or open surgery. It may help improve which approach is best for people having planned prostate removal.
AgenAges 18 years+ - NCT04951817Recruiting
PSMA PET/CT scan to assess Ra-223 treatment in advanced prostate cancer
This trial studies whether a special whole-body scan (PSMA PET/CT) can help assess how well Ra-223 (a targeted treatment) may work in men with advanced prostate cancer that has spread to the bones. It may help doctors choose and plan Ra-223 treatment more effectively.
Taoyuan CityAges 40–85 - NCT05033301Recruiting
Nurse Ned Clinic support for prostate cancer survivors
This study tests a nurse-led clinic (“Nurse Ned Clinic”) to see how well it supports men after curative (potentially curative) prostate cancer treatment. It may help you manage follow-up care during survivorship if you are at low risk of cancer coming back.
Toronto, OntarioAges 18 years+ - NCT05381103RecruitingPhase 2/Phase 3
PSMA scan to plan prostate surgery and help protect erections
This trial tests whether using a PSMA-PET scan before prostatectomy can guide surgery in a way that helps preserve sexual function. It may be most helpful if you have certain kinds of prostate cancer and want to keep erections after surgery.
Indianapolis, IndianaAges 40–80 - NCT05435495Recruiting
Study why PSMA radioligand therapy stops working
This study looks at tissue samples from tumors to understand how and why PSMA radioligand therapy may become less effective. If you have PSMA-avid cancer lesions that can be biopsied, the trial may help researchers find ways to improve treatment.
Los Angeles, CaliforniaAges 18 years+ - NCT05488548RecruitingPhase 1
Study drug that blocks BET and CBP/p300 in advanced cancers
This Phase 1 trial tests an investigational medicine that targets BET and CBP/p300 to try to slow or control advanced, hard-to-treat cancers. You may be eligible if you have certain prostate cancer or NUT midline carcinoma, or specific blood cancers like CMML or myelofibrosis (MF), and your body functions are strong enough for chemotherapy-style treatment.
Phoenix, ArizonaAges 18 years+ - NCT05558007RecruitingPhase 2
Topical treatment trial after prostate surgery in men
This Phase 2 study tests how safe and effective a topical medicine (BZ371A) is for men after prostate surgery, with the goal of improving sexual recovery and monitoring side effects. You may be able to join if you meet specific timing, health, and medication criteria after radical prostatectomy.
Belo HorizonteAges 40–65 - NCT05710861Recruiting
Focal HIFU versus prostate surgery: cost and quality of life
This trial compares focal HIFU (a targeted heating treatment inside the prostate) with prostate surgery, looking at overall cost and quality of life. It may help people with certain early, limited prostate cancers understand which option fits best for them.
BesançonAges 50–75 - NCT05722392Recruiting
Two-step surgery for localized prostate cancer
This trial studies a “two-step” type of prostate removal surgery for men with localized prostate cancer, focusing on whether it is safe and effective. It may help if you have certain prostate size, PSA level, and tumor features that match their criteria.
Guangzhou, GuangdongAges Any age - NCT05745844Recruiting
Electro-stimulation plus exercise for prostate cancer muscle health
This trial tests whether adding neuromuscular electrical stimulation to an exercise program can improve strength and physical function in men with prostate cancer who are on hormone-blocking treatment. It may help prevent or reduce muscle weakness that can happen during androgen deprivation therapy.
AnnemasseAges 18–90 - NCT05761093Recruiting
Share your treatment preferences for metastatic prostate cancer
This study asks people with metastatic prostate cancer and their doctors about what benefits and risks matter most when choosing treatment. Your answers can help improve how treatment options are discussed in Hong Kong.
ShatinAges 18 years+ - NCT05762198Recruiting
Rezūm vs TURP for blocked urine from enlarged prostate
This study compares two procedures—Rezūm (water vapor therapy) and TURP (a surgery)—for men whose urine blockage is not improving. The goal is to see which option works better and is safer for relieving urinary retention due to an enlarged prostate.
Hong KongAges 50–80 - NCT05802121RecruitingEarly Phase 1
Testing a gut bacteria supplement side effects during prostate hormone therapy
This early-phase study looks at how changing gut bacteria (especially Akkermansia) affects metabolic side effects in men starting prostate hormone therapy (ADT). It may help researchers understand how to reduce or manage side effects for people on ADT.
London, OntarioAges 18 years+ - NCT05975775Recruiting
Laparoscopic prostate surgery for localized cancer, as an outpatient
This trial looks at a planned, minimally invasive (laparoscopic) prostate removal for men with localized prostate cancer done as an outpatient. It aims to understand how this approach fits into care after discussion by a group of specialists.
LyonAges 18 years+ - NCT06039085Recruiting
Electrical sensing for real-time cancer margin check during prostate surgery
This study tests a new device that uses tiny electrical sensors to help surgeons check if all the cancer has been removed during prostate cancer surgery. It could give real-time feedback so the surgeon can remove leftover cancer right away.
Lebanon, New HampshireAges 18 years+ - NCT06084338RecruitingPhase 2
Focused Radiation Therapy Without Hormone Therapy for Advanced Prostate Cancer
This trial tests whether giving focused radiation to many cancer spots (SBRT) can work without using testosterone-blocking hormone therapy. It is for men whose prostate cancer has spread and is no longer responding to low testosterone, and who have already tried one of the newer hormone drugs.
West Los Angeles, CaliforniaAges 18 years+ - NCT06111313RecruitingPhase 2
Prostate cancer trial testing targeted radiation with hormone therapy
This trial tests a new radiation approach for prostate cancer that has not spread. It combines different types of radiation with or without hormone therapy to see if this approach works better with fewer side effects.
Miami, FloridaAges 35–85 - NCT06163924Recruiting
Heart risk reduction in prostate cancer patients on hormone therapy
This study tests whether a team of doctors, nurses, and other specialists can help reduce the risk of heart problems in men with prostate cancer who are on hormone therapy (ADT). It focuses on providing extra support for heart health.
Hong KongAges 18–80
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Common questions
- Are there clinical trials for prostate cancer?
- Yes. Clin2 currently lists 1,219 recruiting prostate cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a prostate cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a prostate cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.