Prostatic Hyperplasia clinical trials

A Study of the Beacon Platform for Holmium Laser Enucleation of the Prostate (HoLEP)

GreenLight or ThuLEP surgery for a very enlarged prostate

This trial compares two types of laser surgery for people with a very enlarged prostate causing bothersome urinary symptoms after medicine didn’t help. It aims to find which approach works better and is safer for improving urine flow and quality of life.

Medication for moderate prostate symptoms in sexually active men

This study tests whether a medication can help men with moderate urinary symptoms from an enlarged prostate. It's for men who are already on prostate medicine and have been closely monitored for 12 weeks.

Study of a single tool for prostate surgery using laser or bipolar energy

This study is testing a new way to perform prostate surgery using a single tool that can use either laser or bipolar energy. It aims to see if this approach is safe and effective for men with a large prostate (40 cc or more) who need surgery to help with urination problems.

Text reminders after prostate surgery

This trial tests if text message reminders help men recover urinary control after prostate surgery. If you are planning prostate surgery and can use a mobile phone for texts, you may be able to join.

Comparing laser treatments for enlarged prostate

This study compares three different surgical laser techniques to treat benign prostate enlargement (BPH) that causes severe urinary symptoms and hasn't improved with medication. The goal is to find which method is safest and works best for large prostates.

Pelvic floor therapy before prostate surgery for leaking

This trial tests if doing pelvic floor physical therapy before prostate surgery (HoLEP) helps reduce stress urinary incontinence (leaking after sneezing, coughing, or laughing). It may help patients who are scheduled for this surgery due to an enlarged prostate.

Herbal medicine plus tamsulosin for better sleep after prostate surgery

This study looks at whether a Chinese herbal medicine (Lingze) combined with tamsulosin can help you sleep better and reduce nighttime urination after prostate surgery. It aims to improve your comfort and recovery.

Registry study of MIUS for enlarged prostate

This study collects information from men treated with a minimally invasive surgery called MIUS for an enlarged prostate that blocks urine flow. It aims to learn how well the procedure works by tracking results over time.

Beacon platform study for prostate surgery

This trial tests a new surgical platform called Beacon during HoLEP, a common procedure to treat enlarged prostate symptoms. It may help men with difficulty urinating due to an enlarged prostate.

Two laser systems for prostate surgery: which works better?

This study compares two different laser technologies used during a minimally invasive prostate surgery called HoLEP. You'll be randomly assigned to one laser type and asked to complete brief surveys online after your procedure to help doctors understand which works best for reducing urinary symptoms.

Comparing Two Laser Types for Prostate Surgery

This study compares two different laser techniques (HoLEP and ThuLEP) for treating an enlarged prostate that's causing urinary symptoms. Both are minimally invasive surgical options; the trial will help determine which works better for symptom relief.

Prostate Surgery Comparing Two Methods to Preserve Ejaculation

This trial tests two surgical approaches for enlarged prostate—one specifically designed to preserve the ability to ejaculate and a standard approach—in men with urinary symptoms who haven't improved with medication. You'll be asked about sexual and urinary function before and after surgery.

Prostate steam therapy guided by MRI/ultrasound fusion

This study tests a new steam treatment for enlarged prostate that uses MRI and ultrasound images together to guide the procedure. It aims to relieve urinary symptoms when medications haven't worked or you prefer not to take them.

TUMT vs PAE to ease severe urinary symptoms from an enlarged prostate

This trial compares two catheter-based treatments—TUMT and PAE—to see which better reduces severe urinary symptoms caused by an enlarged prostate (BPH). It may help you choose a treatment option if medicines are not suitable or you still have significant symptoms.

Comparing two surgeries for enlarged prostate

This trial compares two types of surgery for men with an enlarged prostate (BPH) whose symptoms haven't improved with medication. The goal is to see which procedure works better.

Dutasteride before prostate laser surgery and recovery outcomes

This study looks at whether taking dutasteride for at least 6 months before prostate laser surgery affects surgery results and recovery. It includes men having a specific type of prostate surgery called HoLEP.

Electrical stimulation for urinary incontinence after prostate cancer treatment

This trial tests a non-surgical, non-drug treatment that uses gentle electrical stimulation on the skin to help strengthen the muscles that control urine leakage. It's for men who still have urinary incontinence at least 6 months after their prostate cancer treatment.

Smaller vs larger scope for prostate surgery: a study

This study compares two sizes of a surgical device (a sheath) used during laser prostate surgery for men with an enlarged prostate. It aims to see if a smaller sheath works as well as the standard larger one, which could make recovery easier.

Urine markers for enlarged prostate check

This study looks at two natural substances in urine (BDNF and NGF) to see if they can help doctors understand how the lower urinary tract is working in men with an enlarged prostate. It is a simple, non-invasive test that may lead to better ways to diagnose and treat bladder problems.

Comparing two treatments for enlarged prostate

This study compares two minimally invasive devices (iTind and UroLift) to treat urinary symptoms caused by an enlarged prostate. It is for men whose symptoms are bothersome enough to need treatment.

Low Power HOLEP Versus TURP

Tamsulosin alone or with tadalafil for enlarged prostate symptoms

This study tests whether taking tadalafil (at 2.5 mg or 5 mg) along with tamsulosin is better for treating urinary symptoms caused by an enlarged prostate than taking tamsulosin alone. It aims to find the best dose combination to improve your quality of life.

Stopping or continuing blood thinners during prostate vaporization

This study compares whether people can safely stop or continue oral blood thinners during a prostate procedure called photovaporization. It may help reduce bleeding risk without increasing dangerous clot risks for the right patients.