Clinical trials
Psychotherapy clinical trials
Below are recruiting psychotherapy clinical trials, each written for real people, not researchers. We’re tracking 141 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06898606RecruitingPhase 1/Phase 2
Psilocybin mushrooms with or without Prozac for stubborn depression
This study tests whether a dose of psilocybin (the active ingredient in magic mushrooms) can help treat depression that hasn't improved with standard antidepressants. Some participants will also take the antidepressant fluoxetine (Prozac) to see if it changes the effects.
Foz do Iguaçu, ParanáAges 25–65 - NCT04356924Recruiting
Talking therapy to help with worries from mild memory problems
This trial studies a psychological (talking) treatment to help people cope with everyday life challenges caused by mild cognitive impairment or subjective cognitive decline. It may help reduce anxiety, avoidance, and feelings of stigma linked to memory or thinking changes.
Stockholm, Stockholm CountyAges 45–75 - NCT06722781Recruiting
Online group therapy for common mental health conditions
This trial tests an online group therapy for people waiting for high intensity CBT. It aims to provide quicker support for conditions like depression, anxiety, and PTSD.
Doncaster, South YorkshireAges 17 years+ - NCT06835556Recruiting
Studying paranoia changes with talk therapy
This trial tests how a type of talk therapy affects paranoia in people with schizophrenia or related conditions. It aims to understand if daily changes in paranoia can improve with treatment.
Nashville, TennesseeAges 18–65 - NCT06833567Recruiting
Mentalizing therapy for anxiety and depression
This study tests a group therapy that helps people understand their own and others' thoughts and feelings. It may help if you have anxiety or depression and can talk in a group setting.
Málaga, MalagaAges 18 years+ - NCT06801041RecruitingPhase 2
Psilocybin therapy for anxiety or depression in cancer survivors
This trial tests if a single dose of psilocybin, given with therapy, can help cancer survivors who struggle with anxiety or depression. You would travel to MD Anderson for treatment and follow-up, and must stop certain medications beforehand.
Houston, TexasAges 18 years+ - NCT06728579RecruitingPhase 2
Group therapy for joint pain in breast cancer survivors
This study tests two supportive group programs—one using mindfulness skills, the other providing supportive talk therapy—to help breast cancer survivors manage joint pain caused by hormone-blocking pills. If you have ongoing joint pain and are taking an aromatase inhibitor, you may be able to join a free, video-based group.
San Diego, CaliforniaAges 18 years+ - NCT06696001Recruiting
Brain Study of Talk Therapy for Depression
This study looks at how your brain works during talk therapy for depression. It aims to find out how therapy helps you feel better so that future treatments can be more personalized.
Chapel Hill, North CarolinaAges 18–30 - NCT06689072Enrolling by invitation
High-frequency brain stimulation for opioid use disorder
This study tests whether a treatment called repetitive transcranial magnetic stimulation (rTMS) can help people with opioid use disorder. It involves a non-invasive procedure that uses magnetic pulses to stimulate certain parts of the brain.
Asyut, Asyut GovernorateAges 18–45 - NCT06623981Recruiting
Treating maternal depression in an urban asthma clinic
This study tests whether treating depression in Black mothers of children with asthma can improve both the mother's mood and the child's asthma. It offers support for mothers who are feeling down and may help their child's asthma get better.
Washington D.C., District of ColumbiaAges Any age - NCT06622993Recruiting
Skills program for managing psychiatric disorders
This study tests a program called SKILLS to help people with psychiatric disorders learn practical coping strategies. If you are 18 or older, have a psychiatric diagnosis, and are stable on medication, you may be able to join.
ToursAges 18–100 - NCT06630351Enrolling by invitation
Meaning-centered group therapy for caregiver wellbeing
This study tests whether group therapy focused on meaning and purpose can improve the wellbeing of people caring for someone with advanced cancer or another serious illness. Caregivers will join virtual group sessions and complete questionnaires about their feelings and stress.
Jacksonville, FloridaAges 18 years+ - NCT06597695RecruitingPhase 1/Phase 2
Ketamine group therapy for Spanish-speaking adults with depression
This trial tests whether ketamine-assisted group therapy can help Spanish-speaking Latinx adults with major depression. You would receive ketamine in a supportive group setting, with the goal of improving your mood and quality of life.
Chelsea, MassachusettsAges 18–64 - NCT06493708Recruiting
EMDR Therapy for Borderline Personality Disorder
This study tests whether Eye Movement Desensitization and Reprocessing (EMDR) therapy can help people with Borderline Personality Disorder (BPD). EMDR is a type of talk therapy often used for trauma, and this trial wants to see if it can improve BPD symptoms.
Brescia, BresciaAges 18–65 - NCT06480019Recruiting
Group talk therapy for depression in young adults
This study tests if a group therapy program led by non-professionals can help reduce depressive symptoms in young adults aged 18-24 who live, work, or study in Porto Alegre, Brazil. You may benefit if you have mild to moderate depression but no risk of suicide.
Porto Alegre, Rio Grande do SulAges 18–24 - NCT06446765RecruitingPhase 2
Mindfulness and brain feedback to boost BPD therapy
This study tests whether combining mindfulness training with brain scan feedback (neurofeedback) can improve the benefits of regular talk therapy for adults with borderline personality disorder. It takes place at Yale University.
New Haven, ConnecticutAges 18–60 - NCT06458933RecruitingPhase 2
Couples therapy for borderline personality disorder
This study tests talk therapy for couples where one person has borderline personality disorder (BPD). It aims to see if the therapy helps improve symptoms and relationship quality.
Toronto, CaliforniaAges 19 years+ - NCT06091306Recruiting
Study of family therapy for teens with anorexia
This study looks at how families change during a special type of therapy called multifamily therapy (where several families meet together) for teens with anorexia nervosa. The goal is to understand what helps families improve, so doctors can make treatment better.
Paris, Île-de-France RegionAges 6 years+ - NCT06430541RecruitingPhase 1
Psilocybin therapy for fear of cancer recurrence
This trial tests if psilocybin-assisted therapy can help reduce the intense worry that cancer might come back. It is for people who have finished their main treatments for early-stage breast cancer or advanced ovarian cancer.
Aurora, ColoradoAges 21 years+ - NCT06418178RecruitingPhase 2
Optimizing MDMA therapy dose for PTSD in veterans
This trial tests different doses of MDMA (a drug sometimes called 'ecstasy') combined with therapy to see which dose works best for treating PTSD in veterans. The goal is to find a safer, more effective dose to help reduce PTSD symptoms.
The Bronx, New YorkAges 18 years+ - NCT06369532Recruiting
Brain stimulation and therapy to stop worrying
This trial combines a gentle brain stimulation technique called tDCS with cognitive-behavioral therapy (a type of talk therapy) to help people with generalized anxiety disorder or depression stop worrying.
Ghent, East-FlandersAges 18–70 - NCT05833087Recruiting
Schema therapy for long-lasting, hard-to-treat depression
This study tests whether schema therapy can help people with chronic depression that hasn’t improved enough with standard antidepressant treatments. You’d be in a psychiatric clinic and be assessed for severity and diagnosis, then receive the therapy being studied.
Ballerup MunicipalityAges 18–65 - NCT06295250Recruiting
Help for depression and poverty in Bangladesh
This study tests a program in Bangladesh that helps people with depression and poverty. You and your family would work together to improve your mood and financial situation over 18 months.
Dhaka, Dhaka DivisionAges 18–45 - NCT06273137Recruiting
Positive affect treatment for teens with early adversity
This trial tests a treatment designed to improve positive emotions in adolescents who have experienced stressful early life events. It may help your teen build resilience and emotional wellbeing.
Irvine, CaliforniaAges 12–16
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Common questions
- Are there clinical trials for psychotherapy?
- Yes. Clin2 currently lists 141 recruiting psychotherapy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a psychotherapy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a psychotherapy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.