Clinical trials
Pulmonary Artery Hypertension clinical trials
Below are recruiting pulmonary artery hypertension clinical trials, each written for real people, not researchers. We’re tracking 175 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06941441RecruitingPhase 3
Exercise and medicine study for pulmonary arterial hypertension
This trial tests whether adding the study drug sotatercept to your current PAH therapy along with a home exercise program can help you feel better and be more active. It's for people with certain types of PAH who are stable on their current treatment.
Seattle, WashingtonAges 18 years+ - NCT06350032RecruitingPhase 3
Testing treprostinil safety in children with PAH
This trial tests a medicine called treprostinil in children with severe pulmonary arterial hypertension (high blood pressure in the lungs). The study aims to see if it is safe and tolerable for kids who need this kind of therapy.
Vienna, State of ViennaAges Up to 18 years - NCT06968962Recruiting
Starting PAH treatment: one drug first or two drugs together?
This study compares starting with one medication versus two medications together for people with pulmonary arterial hypertension (PAH). It aims to find out which approach works better for low- or intermediate-risk patients.
Hangzhou, ZhejiangAges 18–80 - NCT06649110RecruitingPhase 1/Phase 2
A study of LTP001 for healthy people and those with PAH
This study tests an investigational medicine called LTP001 for pulmonary arterial hypertension (PAH). Part A checks safety in healthy volunteers, and Part B tests if it helps people with PAH by improving blood flow in the lungs.
Scottsdale, ArizonaAges 18–100 - NCT06549452Recruiting
Mobile health app to help teens with pulmonary hypertension exercise
This trial tests whether a smartphone app can help adolescents with pulmonary hypertension stay active and improve their health. If you are a teen with stable PH and can use an activity tracker, this study may be a good fit.
Nashville, TennesseeAges 10–21 - NCT06274801RecruitingPhase 3
Long-term study of seralutinib for pulmonary arterial hypertension
This trial is for people with pulmonary arterial hypertension (PAH) who have already completed a previous study of the drug seralutinib. It offers continued access to the treatment so doctors can watch its safety and effects over a longer time.
Fresno, CaliforniaAges 18–75 - NCT05967299RecruitingPhase 1
IV ZMA001 study in healthy adults
This Phase 1 trial tests how an IV medicine called ZMA001 behaves in healthy people and checks for early safety. It may help future studies of the drug by confirming dosing and effects in people before testing in patients.
Bethesda, MarylandAges 18–60 - NCT05452889RecruitingEarly Phase 1
PET scan study in pulmonary hypertension related to scleroderma
This early study uses a PET scan (a type of imaging test) to better understand lung blood-vessel disease in people who have pulmonary hypertension related to scleroderma. It may help researchers find how imaging signals relate to disease and risk.
Pittsburgh, PennsylvaniaAges 18–75 - NCT07322133RecruitingPhase 4
Comparing two blood pressure medicines for newborns with lung hypertension
This trial compares two medicines (dopamine and norepinephrine) to see which works better for raising blood pressure in newborns who have both low blood pressure and high blood pressure in the lungs. Both medicines are given through a vein to help stabilize your baby's blood pressure.
Sacramento, CaliforniaAges Up to 4 weeks - NCT05110066Recruiting
Compare two procedures for chronic lung blood-clot pressure
This study compares balloon pulmonary angioplasty versus pulmonary endarterectomy for people with chronic thromboembolic pulmonary hypertension (high blood pressure in the lungs due to long-lasting blood clots). It may help find which procedure works better for improving symptoms and lung circulation after treatment.
AarhusAges 18–79 - NCT05442671Recruiting
Exercise coaching program for children with pulmonary hypertension
This trial tests whether a structured exercise program, done with remote support, is safe and helpful for children with pulmonary hypertension. It aims to improve how well kids function day-to-day while they stay on their usual PH medications.
Philadelphia, PennsylvaniaAges 8–18 - NCT07473700RecruitingPhase 2
Study of TX000045 for lung scarring and high blood pressure in the lungs
This trial tests a new medicine called TX000045 for people who have both lung scarring (interstitial lung disease) and high blood pressure in the lungs (pulmonary hypertension). It aims to see if the drug can help improve breathing and daily function.
Phoenix, ArizonaAges 18–80 - NCT07850934Recruiting
Melatonin for high blood pressure in the lungs of newborns
This trial tests whether giving melatonin to full-term newborns with high blood pressure in their lungs (pulmonary hypertension) can help improve their breathing and oxygen levels. It may offer a new treatment option for babies with this condition.
Cairo, AbbassiaAges Any age - NCT05798923RecruitingPhase 2
Study of a new drug for pulmonary hypertension with lung disease
This trial tests an investigational drug called LAM-001 for people who have pulmonary hypertension (high blood pressure in the lungs) along with a type of lung disease called interstitial lung disease. The drug may help improve symptoms and daily function. This study will see if the drug is safe and helpful for this condition.
Tucson, ArizonaAges 18–85 - NCT07234032RecruitingPhase 3
Long-term follow-up study of TPIP for PH-ILD
This trial is a long-term follow-up study for people who already completed a previous study of an inhaled treprostinil medication (TPIP) for pulmonary hypertension caused by interstitial lung disease (PH-ILD). It tests whether continued treatment with TPIP is safe and effective over a longer period.
Naples, FloridaAges 18 years+ - NCT07179380RecruitingPhase 3
Inhaled treprostinil for pulmonary hypertension related to interstitial lung disease
This study tests an inhaled powder medication called TPIP (treprostinil palmitil inhalation powder) to see if it can improve symptoms and exercise ability in people who have both interstitial lung disease and pulmonary hypertension. The study will compare TPIP against a placebo (a dummy treatment without the active drug) to understand how well it works and if it is safe.
Phoenix, ArizonaAges 18 years+ - NCT07079592Recruiting
Detecting pulmonary hypertension with AI and EKGs
This trial uses an artificial intelligence program to analyze a standard EKG to see if it can detect pulmonary hypertension (high blood pressure in the lungs). It might help find the condition earlier and without invasive tests.
TaipeiAges 50–85 - NCT03854071Recruiting
Heart and health MRI testing in healthy people or patients
This study uses MRI (a scanning test) to develop new ways to measure heart function in both healthy volunteers and people with suspected or known heart disease. It may help researchers create better heart tests that could improve future diagnosis and monitoring.
Sheffield, EnglandAges 20–80 - NCT05679206Recruiting
Postpartum care study for pregnancy blood-pressure complications
This study looks at people with preeclampsia during pregnancy and how their lung blood pressure and related symptoms change after delivery. It may help doctors better monitor and manage postpartum risks, especially involving the heart and lungs.
BernAges 16 years+ - NCT06373289Recruiting
Blood pressure in lung arteries and oxygen levels in preemies
This study tests whether changing oxygen targets in preterm infants with high blood pressure in the lungs (pulmonary hypertension) helps their heart and lungs work better. It may help doctors find the best oxygen levels for these babies.
Birmingham, AlabamaAges 1 month–5 months - NCT05485376Recruiting
Pulmonary artery catheter use in cardiogenic shock patients
This trial studies whether using a special pressure-monitoring tube in the heart’s main artery (a pulmonary artery catheter) helps people who are in cardiogenic shock from weak heart pumping. If you qualify, the goal is to improve how doctors monitor and treat this dangerous, fast-moving condition.
Boston, MassachusettsAges 18–90 - NCT05179876RecruitingPhase 3
Treatment access study for pulmonary hypertension when no other option
This Phase 3 study continues treatment for people with pulmonary hypertension who finished an earlier parent study and have no other approved treatment option. It tests whether continuing their current medicine can help them keep getting benefit and stay safe.
MinskAges 2 years+ - NCT07814118Enrolling by invitation
Understanding how your body works during routine care
This study looks at how different body systems work together in people with various conditions and healthy volunteers. It uses routine medical tests and data to understand health better, which can help improve future care.
New York, New YorkAges 18 years+ - NCT05372263Recruiting
Tracking safety of pulmonary hypertension medicines by computer follow-up
This study checks how safe pulmonary hypertension–targeted medicines (and some calcium-blocking medicines) are over time. It uses a computer system to follow you after diagnosis, looking at outcomes and side effects.
Beijing, Beijing MunicipalityAges 3 months–85 years
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Common questions
- Are there clinical trials for pulmonary artery hypertension?
- Yes. Clin2 currently lists 175 recruiting pulmonary artery hypertension studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pulmonary artery hypertension trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pulmonary artery hypertension trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Pulmonary Hypertension
- Pulmonary Arterial Hypertension
- Chronic Thromboembolic Pulmonary Hypertension
- Pulmonary Arterial Hypertension (PAH) (WHO Group 1 PH)
- Idiopathic Pulmonary Arterial Hypertension
- Pulmonary Hypertension Due to Lung Diseases and Hypoxia
- Pulmonary Hypertension (Diagnosis)
- Pulmonary Hypertension Due to Left Heart Disease
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.