Clinical trials
Pulmonary Vascular Disease clinical trials
Below are recruiting pulmonary vascular disease clinical trials, each written for real people, not researchers. We’re tracking 95 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06711120Recruiting
Comparing two treatments for varicose veins in the lower legs
This study compares two minimally invasive treatments (radiofrequency ablation and microwave ablation) for varicose veins in the small saphenous vein. If your varicose veins cause symptoms like pain, swelling, or heaviness, this trial may help determine which treatment works better.
ChengduAges 18–90 - NCT07466745Recruiting
New Pulmonary Valve Study for Kids Needing Replacement
This study tests a new type of replacement valve for children who need a new pulmonary valve (the valve between the heart and lungs). Researchers want to see if the valve works safely and well in real-world use.
Los Angeles, CaliforniaAges 1.5 years–16 years - NCT06062017Recruiting
Potassium, hydration, and heart health in young adults
This study looks at how potassium and hydration affect heart and kidney health in healthy young adults. It may help you understand your own health and contribute to new knowledge about preventing disease.
Auburn, AlabamaAges 18–30 - NCT07261293Recruiting
Blood flow restriction exercise for COPD patients
This study tests whether adding mild blood flow restriction to aerobic exercise can improve lung function, exercise capacity, and inflammation in people with stable COPD. You would exercise on a bike or treadmill while wearing soft cuffs on your legs to lightly restrict blood flow.
IstanbulAges 40–80 - NCT05454267Recruiting
Study early blood vessel changes from vaping
This study looks for early signs of blood vessel problems in people who vape and in healthy non-vapers. It may help researchers find ways to detect and prevent vaping-related vascular disease early.
Miami, FloridaAges 18–40 - NCT03630211RecruitingPhase 2
Study of stem cell transplant for systemic sclerosis in youth
This Phase 2 study tests whether an “autologous” stem cell transplant—using your own stem cells—can reduce systemic sclerosis disease activity. It is mainly for children, teens, and young adults whose disease did not improve despite standard medicines.
Pittsburgh, PennsylvaniaAges 8–60 - NCT03253705Recruiting
Donate small blood samples to study heart and inflammation health
This study collects small blood samples (and sometimes samples during treatment) to help researchers understand diseases involving the heart, inflammation, and blood vessel function. It may help improve future tests and treatments by giving scientists usable human data.
Bethesda, MarylandAges 18–100 - NCT06488638Recruiting
Beetroot juice supplement for lung fibrosis
This trial tests whether a beetroot juice drink (rich in nitrates) can help people with idiopathic pulmonary fibrosis breathe better and exercise more. It's a small pilot study to see if it's safe and worth studying further.
SouthamptonAges 18–85 - NCT06336798RecruitingPhase 2
Pioglitazone for pulmonary hypertension from lung disease
This trial tests if pioglitazone, a medicine used for diabetes, can help people with high blood pressure in their lungs caused by chronic lung disease. The goal is to see if it improves how your cells use energy.
Atlanta, GeorgiaAges 18 years+ - NCT07359664Recruiting
Eye scans for heart health: a study of blood vessels
This study uses an eye scan called OCTA to look at blood vessels in the retina. It compares people with certain heart or blood vessel conditions (like high blood pressure or diabetes) to healthy volunteers to see if eye changes can help detect heart disease early.
Erlangen, BavariaAges 18–75 - NCT05215171Recruiting
Study breathing and blood changes after 9/11 exposure
This study looks at how breathing problems and blood vessel/heart issues may happen after World Trade Center (WTC) dust exposure. It uses blood samples and breathing tests to understand who may be affected and to compare people with and without WTC-related airway reactivity.
New York, New YorkAges 21–90 - NCT06129240Recruiting
Study of a new inhaled treprostinil powder for PH-ILD
This study tests a new dry powder inhaled medicine called LIQ861 for people with pulmonary hypertension related to lung scarring (PH-ILD). If you are already taking an inhaled treprostinil treatment but need better control, this trial may help you switch to a potentially easier-to-use version.
Phoenix, ArizonaAges 18–80 - NCT04521699Recruiting
CalmiGo stress device to improve heart blood vessel health
This study looks at whether a stress-management device (CalmiGo) can improve blood vessel function and heart disease risk in people recovering from recent heart procedures. You would use the device for 12 weeks and complete questionnaires, blood tests, and a heart-vessel test at the start and end.
Rochester, MinnesotaAges 18 years+ - NCT06104228RecruitingPhase 2
Xenon MRI to detect and track pulmonary hypertension
This trial uses a special MRI scan (using xenon gas) to see how well the lungs are working in people with pulmonary arterial hypertension (PAH). It aims to improve diagnosis and monitoring of PAH from connective tissue disease or unknown cause.
Durham, North CarolinaAges 18–75 - NCT07223437Recruiting
Restricted exercise for peripheral artery disease study
This study tests a new type of exercise that uses a blood-flow restriction cuff to see if it helps people with leg pain from blocked arteries. If you have stable claudication (leg pain when walking) and have been referred to cardiac rehab, you may qualify.
Knoxville, TennesseeAges 18 years+ - NCT07285655RecruitingPhase 3
Study of L606 for lung disease with high blood pressure in the lungs
This trial tests a new treatment called L606 for people who have both a type of lung disease (ILD) and high blood pressure in the lungs (PH). The goal is to see if it is safe and helps with exercise and breathing.
Phoenix, ArizonaAges 18–80 - NCT06041594Recruiting
Treating pulmonary embolism with the Laguna thrombectomy system
This trial tests a device (Laguna Thrombectomy System) to remove blood clots in the lungs. It may help people with a recent pulmonary embolism who are stable enough to undergo a minimally invasive procedure.
Birmingham, AlabamaAges 18–85 - NCT07356778RecruitingPhase 4
Study of sotatercept for Eisenmenger syndrome patients
This trial tests a new drug called sotatercept for people with Eisenmenger syndrome or a related heart defect that hasn't been repaired. It may help if current treatments aren't working well enough.
Fukuoka, Not Required For This CountryAges 18 years+ - NCT06554301RecruitingPhase 1
Empagliflozin for pulmonary arterial hypertension study
This study tests if the diabetes drug empagliflozin can help people with pulmonary arterial hypertension (PAH), a condition causing high blood pressure in the lungs. It aims to see if the drug improves symptoms and is safe for patients with moderate symptoms.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06099015Recruiting
Cera vascular plug study for blocking blood vessels
This study tests a device called the Cera Vascular Plug System to block blood flow in certain arteries or veins. It may help patients who need this type of treatment for conditions like abnormal blood vessels or bleeding.
Bad HersfeldAges 18–85 - NCT04062565RecruitingPhase 3
Testing treprostinil plus riociguat for advanced pulmonary artery hypertension
This study tests whether taking injected treprostinil together with riociguat can improve how the heart and lung blood vessels work in people with advanced pulmonary artery hypertension (PAH). It may help improve blood-flow measurements and the structure of the heart.
Tucson, ArizonaAges 18 years+ - NCT04010526RecruitingPhase 2
Local treatment for Crohn’s fistulas using your own fat cells
This Phase 2 trial studies whether a local injection of fat-derived cells (made from your own tissue) can improve difficult Crohn’s disease fistulas around the anus. It’s designed for people whose Crohn’s fistulas have not responded to usual treatments.
Marseille, PACAAges 18 years+ - NCT01851642Recruiting
Study how lung disease affects white blood cells
This study looks at how lung disease changes a type of blood cell called white blood cells. It may help researchers understand what’s happening in the lungs and how to better monitor or treat lung problems.
Gainesville, FloridaAges 18 years+
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Common questions
- Are there clinical trials for pulmonary vascular disease?
- Yes. Clin2 currently lists 95 recruiting pulmonary vascular disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pulmonary vascular disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pulmonary vascular disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.