Clinical trials
Recurrence clinical trials
Below are recruiting recurrence clinical trials, each written for real people, not researchers. We’re tracking 1,384 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06788990RecruitingPhase 2/Phase 3
Study of ficerafusp alfa with pembrolizumab for advanced head and neck cancer
This study tests a new drug called ficerafusp alfa (BCA101) combined with the immunotherapy pembrolizumab for people with advanced head and neck cancer that has not been treated before. The goal is to see if adding ficerafusp alfa helps shrink tumors better than pembrolizumab alone.
Birmingham, AlabamaAges 18 years+ - NCT06785415RecruitingPhase 1/Phase 2
Study of a drug combo for relapsed multiple myeloma
This trial tests a combination of two antibody drugs (elotuzumab and daratumumab) plus an oral pill (iberdomide) and a steroid (dexamethasone) for people whose multiple myeloma has come back after treatment. The goal is to see if this new mix works better than what's already available.
Rochester, MinnesotaAges 18 years+ - NCT06781879RecruitingPhase 4
Comparing bladder medication vs surgery for returning low-grade bladder cancer
This trial tests whether a chemotherapy drug placed directly into the bladder (chemoablation) works as well as surgery followed by chemotherapy for people whose low-grade bladder tumors have come back. It aims to find a less invasive option that still controls the cancer.
AalborgAges 18 years+ - NCT06770582RecruitingPhase 2
Adding immunotherapy to radiation for bladder cancer
This trial tests whether adding the immunotherapy drug pembrolizumab to radiation therapy works as well as or better than the usual chemotherapy given with radiation for a type of bladder cancer that has not invaded the muscle. It is for people whose cancer came back or has high-risk features and who would otherwise need to have their bladder removed.
Tucson, ArizonaAges 18 years+ - NCT06767800RecruitingPhase 2
Study of TQB2102 with immunotherapy for HER2-positive gastroesophageal cancer
This trial tests a new combination of drugs (TQB2102, benmelstobart, and pembrolizumab) with or without chemotherapy for people with HER2-positive gastroesophageal cancer that cannot be removed by surgery or has spread. It aims to see if this combination is more effective than current treatments.
Fuyang, AnhuiAges 18–75 - NCT06763965Enrolling by invitationPhase 1/Phase 2
BioTTT001 for recurrent high-grade glioma
This trial tests a new drug called BioTTT001 for people whose high-grade brain tumor has come back after standard treatment. The drug is given through a small device placed in the head to deliver it directly to the tumor area.
Beijing, Chaoyang DistrictAges 18 years+ - NCT06763341RecruitingPhase 1
Study of AOH1996 for relapsed or refractory acute myeloid leukemia
This trial tests an experimental drug called AOH1996 for people with acute myeloid leukemia (AML) that has come back or not responded to other treatments. The goal is to see if the drug is safe and helps control the leukemia.
Duarte, CaliforniaAges 18 years+ - NCT05894070Recruiting
Using your voice recordings to spot cancer coming back
This study looks at whether changes in your voice can help detect early return of laryngeal or hypopharyngeal cancer. If you’ve finished curative treatment and are disease-free for a certain period, your voice will be monitored to see if it can signal recurrence sooner.
BernAges 18 years+ - NCT06755515Enrolling by invitationPhase 2/Phase 3
Rulonilimab + Chemo for Advanced Cervical Cancer
This trial tests a new drug called Rulonilimab combined with chemotherapy, with or without bevacizumab, as the first treatment for cervical cancer that has spread or come back. It’s for people whose tumors have a specific marker (PD-L1) and who haven’t had other treatments for advanced disease.
Linyi, ShandongAges 18 years+ - NCT04532606RecruitingPhase 4
Remimazolam to improve outcomes after bladder tumor surgery
This trial tests whether the anesthesia medicine remimazolam can improve recovery and longer-term outcomes after surgery for early-stage bladder cancer. If you are having a bladder tumor procedure through the urethra, this study may help doctors understand whether this anesthesia choice matters for prognosis.
Beijing, Beijing MunicipalityAges 50–90 - NCT06748014Enrolling by invitationEarly Phase 1
Study of aescin plus MPFF for bleeding hemorrhoids
This study tests whether a combination of two medicines (aescin and MPFF) can stop bleeding from mild internal hemorrhoids (grade 1 or 2) and prevent it from coming back. If you have had active bleeding within the past 7 days, this trial may help you find an effective non-surgical treatment.
Chiang Mai, MaungAges 20 years+ - NCT05592886Recruiting
Oral probiotic-and-prebiotic drink to prevent colon polyps returning
This study tests whether an oral synbiotic (a probiotic plus a prebiotic) can reduce the chance that advanced colon growths come back after they were removed. It also looks at changes in stool-related bacterial “gene markers” that may signal lower risk over time.
Hohhot, Inner MongoliaAges 18–90 - NCT06358625Recruiting
Study of brain recurrence risk in HER2-positive breast cancer
This study looks at women with HER2-positive breast cancer who will get chemotherapy before surgery. The goal is to find out what factors might increase the chance of the cancer spreading to the brain later on.
RennesAges 18 years+ - NCT06732323RecruitingPhase 3
Study of ESG401 for triple-negative breast cancer that has spread
This trial tests a new drug, ESG401, for people with triple-negative breast cancer that has come back or spread and cannot be removed by surgery. It compares ESG401 to standard chemotherapy options to see which works better.
BeijingAges 18 years+ - NCT06736288RecruitingPhase 4
Buccalin® tablets to prevent repeat lung infections
This trial tests whether Buccalin® tablets can help adults who get frequent lower respiratory infections (like bronchitis or COPD flare-ups). It's a phase 4 study collecting more data on safety and how well the medicine works to prevent these infections from coming back.
AlessandriaAges 18–99 - NCT06735664RecruitingPhase 1
Zanubrutinib and odronextamab for Richter's transformation
This trial tests a combination of two targeted drugs for people with Richter's transformation, an aggressive lymphoma that can develop from CLL. The goal is to see if this combination can help control the disease.
Duarte, CaliforniaAges 18 years+ - NCT06731933RecruitingPhase 2
Gene therapy for skin cancer in recessive dystrophic epidermolysis bullosa
This trial tests a gene therapy called BVEC to see if it can prevent squamous cell carcinoma (a type of skin cancer) from coming back in people with a severe form of epidermolysis bullosa (fragile skin). It is for adults who have had a confirmed SCC and are willing to use the gene therapy.
Redwood City, CaliforniaAges 18 years+ - NCT06724588Enrolling by invitation
Bacteria and drug resistance in people with repeat UTIs
This study looks at bacteria in urine samples from people who get frequent urinary tract infections and have a certain type of catheter. It aims to learn why some bacteria are hard to treat and may help improve care for patients like you.
LeuvenAges 18 years+ - NCT06725173Recruiting
Retinoblastoma genetics and tumor spread study
This study looks at gene changes in retinoblastoma to understand why some tumors spread outside the eye. It may help find better ways to predict and treat the disease.
Seattle, WashingtonAges Any age - NCT06717919RecruitingPhase 4
Testing HOPE treatment to prevent liver cancer return after transplant
This study tests a special way of preserving donated livers, called HOPE, to see if it lowers the chance of liver cancer coming back after a liver transplant. If you have liver cancer and are waiting for a transplant, this trial might be an option for you.
New York, New YorkAges 18 years+ - NCT06710288RecruitingPhase 2
Immune cell therapy plus chemo for platinum-resistant ovarian cancer
This trial tests a new combination therapy for advanced ovarian cancer that has stopped responding to platinum-based chemo. You will receive your own immune cells (M-CENK) boosted with an immune stimulator (N-803) plus chemotherapy (gemcitabine) to see if this helps fight the cancer.
El Segundo, CaliforniaAges 18–85 - NCT05437965Recruiting
Registry study for repeat coronary blockages after stents
This study follows adults who have fast, unexplained re-narrowing of a coronary stent, to better understand what causes it and how to monitor it. You may help by allowing the study team to collect medical information over time.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06090890RecruitingPhase 4
Anti-inflammatory therapy for repeated stent blockages
This trial tests if anti-inflammatory drugs like prednisone or colchicine can prevent stents from blocking again in people who have already had multiple stent blockages. It may offer a new treatment option for those with recurrent in-stent restenosis.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06703892RecruitingPhase 1
CAR T-cell therapy for relapsed B-cell lymphoma
This trial tests a new type of CAR T-cell therapy that targets two proteins (CD20 and CD19) on your cancer cells. It is for people with certain types of lymphoma that have not responded to or have come back after at least two prior treatments.
TaipeiAges 18–70
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Common questions
- Are there clinical trials for recurrence?
- Yes. Clin2 currently lists 1,384 recruiting recurrence studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a recurrence trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a recurrence trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.