Clinical trials · Houston, TX
Recurrent Glioblastoma clinical trials in Houston
We’re tracking 12 recruiting recurrent glioblastoma studies with a site in or near Houston — including Phase 1, Phase 1/Phase 2, Phase 2/Phase 3 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies near Houston
- NCT03911388RecruitingPhase 1
HSV G207 for Children with Recurrent Cerebellar Brain Tumors
This trial is testing a virus called HSV G207, which is injected directly into the tumor, to treat children and young adults with a type of brain tumor in the cerebellum that has come back or not responded to standard treatments.
Houston, TexasAges 3–22 - NCT06815432RecruitingPhase 1
CAR T cells for recurrent glioblastoma that makes GPC3
This trial tests a treatment made from your own immune cells, called CAR T cells, which are engineered to find and attack brain tumor cells that have a marker called GPC3. It is for patients whose glioblastoma has come back and who are already scheduled to have another surgery to remove the tumor.
Houston, TexasAges 21–70 - NCT06672575RecruitingPhase 1/Phase 2
Ivonescimab for recurrent glioblastoma
This trial tests a new drug called ivonescimab for people whose glioblastoma has come back after standard treatment. The goal is to see if this drug can help shrink the tumor or slow its growth.
Houston, TexasAges 18 years+ - NCT05765812RecruitingPhase 1/Phase 2
Debio 0123 with temozolomide for recurrent or new glioblastoma
This early-phase study tests Debio 0123 (an anticancer medicine) combined with temozolomide, and for newly diagnosed patients also with radiation. It aims to see whether this treatment combination can slow or control glioblastoma in adults.
Houston, TexasAges 18 years+ - NCT07579208RecruitingPhase 1
CAR NK cells for recurrent glioblastoma brain tumors
This trial tests engineered immune cells (called NK cells) that are designed to fight glioblastoma, a deadly brain cancer. The cells are injected directly into the tumor and may help patients whose cancer has come back after standard treatment.
Houston, TexasAges 18 years+ - NCT04991870RecruitingPhase 1
Early-stage immune cell therapy for recurrent grade 4 brain tumors
This Phase 1 trial tests a gene-edited immune cell treatment given into the brain to treat recurrent (returning) grade 4 glioblastoma or related tumors. It aims to find a safe dose and see whether the treatment can slow tumor growth.
Houston, TexasAges 12 years+ - NCT05303467RecruitingPhase 1
Safety study of a glioblastoma device for recurring tumors
This early study tests whether a device called TheraSphere is safe when delivered into the brain to treat recurrent glioblastoma. It may help patients by trying a targeted treatment approach, while doctors carefully monitor side effects and safety.
Houston, TexasAges 18 years+ - NCT03596086RecruitingPhase 1/Phase 2
Study drug plus radiation and chemo for recurrent brain cancer
This Phase 1/2 study tests whether combining an HSV-tk “gene switch” treatment, valacyclovir tablets, focused radiation (SBRT), and chemotherapy can help people with recurrent glioblastoma or anaplastic astrocytoma. It may help shrink tumors or slow growth after standard treatments have already been tried.
Houston, TexasAges 18 years+ - NCT05902169RecruitingPhase 3
Ultrasound with carboplatin for recurrent glioblastoma
This trial tests a device that opens the blood-brain barrier using ultrasound, allowing chemotherapy to reach the brain tumor better. It compares this approach to standard chemotherapy for people whose glioblastoma has returned.
Houston, TexasAges 18 years+ - NCT04427384Recruiting
Brain tumor patients treated with GammaTiles registry
This study is a patient registry for people with brain tumors who had surgery to remove as much as safely possible and then had GammaTiles placed. It mainly collects information and follow-up imaging to understand how patients do after the treatment.
Houston, TexasAges Any age - NCT03896568RecruitingPhase 1
Trial of stem cell therapy for recurrent high-grade brain tumors
This Phase 1 study tests an advanced stem-cell treatment (hMSC-DNX2401) for recurrent high-grade glioma, including certain brain tumor types that come back. It aims to see if the treatment can be safely delivered and whether it can help control the tumor after standard therapies have already been tried.
Houston, TexasAges 18 years+ - NCT03970447RecruitingPhase 2/Phase 3
Testing several treatment options for new or returning glioblastoma
This trial studies different treatment regimens for people with glioblastoma that is either newly diagnosed or has come back. It aims to find which treatment approach works best for controlling the tumor and improving outcomes.
Houston, TexasAges 18 years+
Hear when a new Recurrent Glioblastoma trial opens near Houston, TX
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Recurrent Glioblastoma trials in other cities
Where these studies are running near Houston
Institutions with a site for the recruiting recurrent glioblastoma studies listed above.
- The University of Texas MD Anderson Cancer Center · 8 studies
- Houston Methodist Hospital · 2 studies
- Baylor College of Medicine
- Baylor St. Luke's Medical Center
- Texas Oncology - Gulf Coast
- The University of Texas Health Science Center at Houston
What taking part in a recurrent glioblastoma study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting recurrent glioblastoma studies in Texas.
Common questions
- Are there recurrent glioblastoma clinical trials near Houston?
- Yes. We're currently tracking 12 recruiting recurrent glioblastoma studies with a site near Houston, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a recurrent glioblastoma study near Houston?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Houston to take part?
- Not necessarily. These studies have a site near Houston, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a recurrent glioblastoma trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New recurrent glioblastoma studies open near Houston regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.