Clinical trials
Rheumatoid arthritis clinical trials
An autoimmune condition that causes painful swelling in the joints. We’re tracking 267 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06726096Enrolling by invitationPhase 3
Trial of VDJ001 for moderate to severe rheumatoid arthritis
This trial tests a new medicine called VDJ001 for people with moderate to severe rheumatoid arthritis who are already taking methotrexate. The goal is to see if VDJ001 helps reduce joint pain and swelling better than a placebo.
Beijing, Beijing MunicipalityAges 18–75 - NCT06456489RecruitingPhase 3
Pulse steroids for hard-to-treat rheumatoid arthritis
This trial tests whether a high-dose steroid injection can help people with rheumatoid arthritis that hasn't improved with other treatments. If you have RA that's not well controlled, this may be an option for you.
CairoAges 20–65 - NCT07564154RecruitingPhase 1
Testing KT502 injections for active rheumatoid arthritis
This is an early-stage study testing a new injectable treatment called KT502 for people with moderate-to-severe rheumatoid arthritis (RA) that hasn't responded well to standard treatments. The study will check if the medication is safe and how the body responds to it.
Bayswater, VictoriaAges 18–75 - NCT03976245RecruitingPhase 4
Tested new advanced treatment options for rheumatoid arthritis
This trial studies advanced medicines for rheumatoid arthritis (RA) in people whose RA is still active despite several standard treatments. It may help by testing whether a different advanced option can better control symptoms and joint inflammation.
London, OntarioAges 18 years+ - NCT04292067Recruiting
Study gut bacteria in people with arthritis
This study compares the gut microbiome (the bacteria in your intestines) in adults with spondyloarthritis or rheumatoid arthritis versus healthy adults. It aims to better describe differences that may help explain these diseases.
Boulogne-BillancourtAges 18 years+ - NCT05092984RecruitingPhase 3
Spironolactone for rheumatoid arthritis with active symptoms
This trial tests whether spironolactone can reduce symptoms and inflammation in people with rheumatoid arthritis that is still active despite standard arthritis medicines. You may be able to join if your rheumatoid arthritis remains active and your current treatment plan has been stable for at least several months.
Strasbourg, AlsaceAges 18 years+ - NCT05197530RecruitingPhase 1
Imaging lymph vessels in rheumatoid arthritis before and during treatment
This Phase 1 study uses special imaging to look at lymph vessels in people with rheumatoid arthritis (RA). The goal is to better understand changes in the lymph system in early versus long-standing RA and during certain treatments.
Rochester, New YorkAges 18 years+ - NCT05305066Recruiting
Study for people with rheumatoid arthritis who tried standard medicines
This trial studies an add-on treatment approach for rheumatoid arthritis (RA) in adults whose symptoms did not improve with standard “first-line” medicines. It may help people who still have active RA after trying certain disease-modifying drugs.
Montreal, QuebecAges 18 years+ - NCT05760898Recruiting
Helping control blood pressure in people with rheumatoid arthritis
This study aims to improve blood pressure control in adults who have both uncontrolled high blood pressure and rheumatoid arthritis. It may help by testing ways to better coordinate care between primary care and rheumatology.
Durham, North CarolinaAges 18 years+ - NCT06240299Recruiting
Neurofeedback for chronic pain in rheumatoid arthritis
This trial tests a brain-training technique called neurofeedback to see if it can help people with rheumatoid arthritis who also have chronic widespread pain. It uses a computer to show you your brain activity and teach you to control it, which may reduce pain.
Glasgow, ScotlandAges 18–75 - NCT06289114Recruiting
Can physical activity predict treatment success in rheumatoid arthritis?
This study tests if measuring your physical activity over a short time can help predict how well a new biologic medication will work for your rheumatoid arthritis. The goal is to find a simple way to see if the treatment is helping.
EsbjergAges 18 years+ - NCT06527534RecruitingPhase 4
Filgotinib vs adalimumab for rheumatoid arthritis
This study compares two RA medications, filgotinib and adalimumab, to see how they affect your body's proteins and genetic signals. It may help your doctor know which treatment is better for your type of RA.
VeronaAges 18–65 - NCT06572696Recruiting
Shoulder Ultrasound in Rheumatoid Arthritis Without Pain
This study uses ultrasound to look for hidden shoulder problems in people with rheumatoid arthritis who have no shoulder pain. It aims to find early changes that might need treatment before pain starts.
IstanbulAges 18–75 - NCT06640309RecruitingPhase 2
Nicotinamide for rheumatoid arthritis: a clinical trial
This trial tests if taking a vitamin B3 supplement (nicotinamide) can improve outcomes for people with rheumatoid arthritis. Researchers want to see if adding this over-the-counter vitamin to your usual arthritis medicines helps reduce disease activity.
CairoAges 18–65 - NCT06753565RecruitingPhase 2
L-carnitine supplement for rheumatoid arthritis
This trial tests whether adding L-carnitine (a natural substance) to your current treatment helps reduce rheumatoid arthritis symptoms. It could be an option if your arthritis is still active despite taking standard medications.
Cairo, DemerdashAges 18–60 - NCT07234773RecruitingPhase 1
Study of a new injectable drug for rheumatoid arthritis
This early-stage study tests a new injectable medicine (KT501) for people with moderate to severe rheumatoid arthritis who have not responded well enough to other treatments and have specific antibodies in their blood. It aims to see how safe and well-tolerated the drug is.
BayswaterAges 18–75 - NCT07245732RecruitingPhase 4
Steroid pills vs. shots for rheumatoid arthritis flares
This trial compares steroid pills to steroid shots for controlling sudden worsening of rheumatoid arthritis symptoms. It aims to find which method works better and is easier for you.
Toronto, OntarioAges 18 years+ - NCT05799768Enrolling by invitation
Ketogenic diet for rheumatoid arthritis symptoms and inflammation
This study tests whether a very low-carbohydrate, ketogenic diet can improve rheumatoid arthritis (RA). It’s designed for people whose RA treatment is already stable and who are not currently using a keto diet or certain medicines.
Oklahoma City, OklahomaAges 18–65 - NCT05413759Recruiting
Helping rheumatoid arthritis patients take medicines on schedule
This study looks at how well people with rheumatoid arthritis (RA) take their RA medicines—especially medicines like methotrexate and other targeted or biologic treatments. It may help improve medication adherence (taking doses correctly) and supports safer, more consistent treatment at home.
Pierre-Bénite, LyonAges 18 years+ - NCT05638854RecruitingPhase 1
Test of ZB002 safety and dosing in rheumatoid arthritis
This early-phase study tests whether ZB002 is safe in people, and how the body handles the drug. It includes both healthy volunteers and people with rheumatoid arthritis (RA) to see if the drug has a predictable blood level pattern.
MelbourneAges 18–70 - NCT06613490RecruitingEarly Phase 1
CAR NK cells for antibody syndrome and rheumatoid arthritis
This early-phase trial tests whether a new type of immune cell (CAR NK) can treat two conditions: antisynthetase antibody syndrome (a rare autoimmune disease) and rheumatoid arthritis. It's for people whose current treatments haven't worked well enough.
Nanjing, JiangsuAges 18–70 - NCT06913907RecruitingPhase 4
Methotrexate injection for new rheumatoid arthritis patients
This study tests a methotrexate injection (given under the skin) for people with moderate to severe rheumatoid arthritis who haven't taken methotrexate before. Researchers want to see how the medicine builds up in your body and if it helps control your symptoms.
Shinjuku-ku, TokyoAges 18 years+ - NCT06965322Recruiting
Detecting lung problems in rheumatoid arthritis
This study uses CT scans and blood tests to look for lung signs related to rheumatoid arthritis. It aims to find lung issues early, which may help in managing the disease better.
Innsbruck, AustriaAges 18 years+ - NCT07301892Recruiting
AI help for rheumatoid arthritis diagnosis
This trial tests whether artificial intelligence (AI) can improve how doctors spot complications in people newly diagnosed with rheumatoid arthritis (RA), a condition that causes joint pain and swelling. The goal is to see if AI can make diagnosis faster and more accurate in real-world hospital settings.
Beijing, Beijing MunicipalityAges Any age
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Common questions
- Are there clinical trials for rheumatoid arthritis?
- Yes. Clin2 currently lists 267 recruiting rheumatoid arthritis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a rheumatoid arthritis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a rheumatoid arthritis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.