Clinical trials
Rheumatoid arthritis clinical trials
An autoimmune condition that causes painful swelling in the joints. We’re tracking 263 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04748809Recruiting
Diet trial for rheumatoid arthritis inflammation
This study tests whether an anti-inflammatory diet can help people with rheumatoid arthritis by lowering inflammation and disease activity. You may join if your symptoms are currently mild to moderate and you haven’t recently changed medications or your treatment plan.
La Jolla, CaliforniaAges 18 years+ - NCT07730723RecruitingPhase 2/Phase 3
Nicorandil for moderate to severe rheumatoid arthritis
This study tests whether a heart medication called nicorandil can help reduce arthritis symptoms when added to your current treatment. It is for people with moderate to severe rheumatoid arthritis who have been stable on their current treatments.
Cairo, AbbasiaAges 18 years+ - NCT06640309RecruitingPhase 2
Nicotinamide for rheumatoid arthritis: a clinical trial
This trial tests if taking a vitamin B3 supplement (nicotinamide) can improve outcomes for people with rheumatoid arthritis. Researchers want to see if adding this over-the-counter vitamin to your usual arthritis medicines helps reduce disease activity.
CairoAges 18–65 - NCT03976245RecruitingPhase 4
Tested new advanced treatment options for rheumatoid arthritis
This trial studies advanced medicines for rheumatoid arthritis (RA) in people whose RA is still active despite several standard treatments. It may help by testing whether a different advanced option can better control symptoms and joint inflammation.
London, OntarioAges 18 years+ - NCT07564154RecruitingPhase 1
Testing KT502 injections for active rheumatoid arthritis
This is an early-stage study testing a new injectable treatment called KT502 for people with moderate-to-severe rheumatoid arthritis (RA) that hasn't responded well to standard treatments. The study will check if the medication is safe and how the body responds to it.
Bayswater, VictoriaAges 18–75 - NCT06753565RecruitingPhase 2
L-carnitine supplement for rheumatoid arthritis
This trial tests whether adding L-carnitine (a natural substance) to your current treatment helps reduce rheumatoid arthritis symptoms. It could be an option if your arthritis is still active despite taking standard medications.
Cairo, DemerdashAges 18–60 - NCT05092984RecruitingPhase 3
Spironolactone for rheumatoid arthritis with active symptoms
This trial tests whether spironolactone can reduce symptoms and inflammation in people with rheumatoid arthritis that is still active despite standard arthritis medicines. You may be able to join if your rheumatoid arthritis remains active and your current treatment plan has been stable for at least several months.
Strasbourg, AlsaceAges 18 years+ - NCT06289114Recruiting
Can physical activity predict treatment success in rheumatoid arthritis?
This study tests if measuring your physical activity over a short time can help predict how well a new biologic medication will work for your rheumatoid arthritis. The goal is to find a simple way to see if the treatment is helping.
EsbjergAges 18 years+ - NCT07245732RecruitingPhase 4
Steroid pills vs. shots for rheumatoid arthritis flares
This trial compares steroid pills to steroid shots for controlling sudden worsening of rheumatoid arthritis symptoms. It aims to find which method works better and is easier for you.
Toronto, OntarioAges 18 years+ - NCT07234773RecruitingPhase 1
Study of a new injectable drug for rheumatoid arthritis
This early-stage study tests a new injectable medicine (KT501) for people with moderate to severe rheumatoid arthritis who have not responded well enough to other treatments and have specific antibodies in their blood. It aims to see how safe and well-tolerated the drug is.
BayswaterAges 18–75 - NCT04292067Recruiting
Study gut bacteria in people with arthritis
This study compares the gut microbiome (the bacteria in your intestines) in adults with spondyloarthritis or rheumatoid arthritis versus healthy adults. It aims to better describe differences that may help explain these diseases.
Boulogne-BillancourtAges 18 years+ - NCT06240299Recruiting
Neurofeedback for chronic pain in rheumatoid arthritis
This trial tests a brain-training technique called neurofeedback to see if it can help people with rheumatoid arthritis who also have chronic widespread pain. It uses a computer to show you your brain activity and teach you to control it, which may reduce pain.
Glasgow, ScotlandAges 18–75 - NCT05799768Enrolling by invitation
Ketogenic diet for rheumatoid arthritis symptoms and inflammation
This study tests whether a very low-carbohydrate, ketogenic diet can improve rheumatoid arthritis (RA). It’s designed for people whose RA treatment is already stable and who are not currently using a keto diet or certain medicines.
Oklahoma City, OklahomaAges 18–65 - NCT05760898Recruiting
Helping control blood pressure in people with rheumatoid arthritis
This study aims to improve blood pressure control in adults who have both uncontrolled high blood pressure and rheumatoid arthritis. It may help by testing ways to better coordinate care between primary care and rheumatology.
Durham, North CarolinaAges 18 years+ - NCT05305066Recruiting
Study for people with rheumatoid arthritis who tried standard medicines
This trial studies an add-on treatment approach for rheumatoid arthritis (RA) in adults whose symptoms did not improve with standard “first-line” medicines. It may help people who still have active RA after trying certain disease-modifying drugs.
Montreal, QuebecAges 18 years+ - NCT05197530RecruitingPhase 1
Imaging lymph vessels in rheumatoid arthritis before and during treatment
This Phase 1 study uses special imaging to look at lymph vessels in people with rheumatoid arthritis (RA). The goal is to better understand changes in the lymph system in early versus long-standing RA and during certain treatments.
Rochester, New YorkAges 18 years+ - NCT07301892Recruiting
AI help for rheumatoid arthritis diagnosis
This trial tests whether artificial intelligence (AI) can improve how doctors spot complications in people newly diagnosed with rheumatoid arthritis (RA), a condition that causes joint pain and swelling. The goal is to see if AI can make diagnosis faster and more accurate in real-world hospital settings.
Beijing, Beijing MunicipalityAges Any age - NCT07274124Recruiting
Pain education and nerve stimulation for rheumatoid arthritis
This study tests whether combining pain education with a mild nerve stimulation device can improve pain and recovery in people with rheumatoid arthritis. It may help you manage long-term pain better.
Istanbul, FatihAges 20–65 - NCT06913907RecruitingPhase 4
Methotrexate injection for new rheumatoid arthritis patients
This study tests a methotrexate injection (given under the skin) for people with moderate to severe rheumatoid arthritis who haven't taken methotrexate before. Researchers want to see how the medicine builds up in your body and if it helps control your symptoms.
Shinjuku-ku, TokyoAges 18 years+ - NCT06613490RecruitingEarly Phase 1
CAR NK cells for antibody syndrome and rheumatoid arthritis
This early-phase trial tests whether a new type of immune cell (CAR NK) can treat two conditions: antisynthetase antibody syndrome (a rare autoimmune disease) and rheumatoid arthritis. It's for people whose current treatments haven't worked well enough.
Nanjing, JiangsuAges 18–70 - NCT06965322Recruiting
Detecting lung problems in rheumatoid arthritis
This study uses CT scans and blood tests to look for lung signs related to rheumatoid arthritis. It aims to find lung issues early, which may help in managing the disease better.
Innsbruck, AustriaAges 18 years+ - NCT05413759Recruiting
Helping rheumatoid arthritis patients take medicines on schedule
This study looks at how well people with rheumatoid arthritis (RA) take their RA medicines—especially medicines like methotrexate and other targeted or biologic treatments. It may help improve medication adherence (taking doses correctly) and supports safer, more consistent treatment at home.
Pierre-Bénite, LyonAges 18 years+ - NCT07627542Recruiting
Smartphone use and neck posture in arthritis patients
This study looks at how much time people with rheumatoid arthritis or ankylosing spondylitis spend on smartphones and how it affects their neck posture, balance, and disability. Understanding this connection may help doctors give better advice about phone use and neck health.
Konya, MeramAges 18–65 - NCT07491016Recruiting
Telitacicept plus baricitinib for hard-to-treat rheumatoid arthritis
This study tests a combination of two drugs (telitacicept and baricitinib) for people with stubborn rheumatoid arthritis that hasn't improved with other treatments. The goal is to see if this combination is safe and effective in reducing joint pain and inflammation.
Hangzhou, ZhejiangAges 18–85
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Common questions
- Are there clinical trials for rheumatoid arthritis?
- Yes. Clin2 currently lists 263 recruiting rheumatoid arthritis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a rheumatoid arthritis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a rheumatoid arthritis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.