Clinical trials
Rheumatoid arthritis clinical trials
An autoimmune condition that causes painful swelling in the joints. We’re tracking 263 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07665086Enrolling by invitation
Isometric exercise for rheumatoid arthritis
This study tests whether simple isometric (holding still) exercises can help people with rheumatoid arthritis. The goal is to see if these exercises improve hand function and quality of life.
DenizliAges 18–65 - NCT07649265RecruitingPhase 1
Testing a new drug for autoimmune diseases
This study tests a new drug called HBM7020 to see if it is safe and how well it is absorbed by the body. It is for healthy people and people with certain autoimmune diseases like lupus, scleroderma, rheumatoid arthritis, or Sjögren's disease.
Brisbane, QueenslandAges 18–75 - NCT07558850Recruiting
CAR-T Cell Therapy for Treatment-Resistant Autoimmune Diseases
This study tests a new type of immune cell therapy (CAR-T cells) designed to treat severe autoimmune diseases like rheumatoid arthritis, lupus, dermatomyositis, and scleroderma that haven't responded well to standard treatments. The therapy works by modifying your own immune cells to target and eliminate the B cells that are causing your autoimmune disease.
Nanjing, JiangsuAges 18–70 - NCT06732674Recruiting
Home-based care for lung disease in rheumatic conditions
This trial tests whether people with lung disease caused by a rheumatic condition can safely manage their care at home using a smartphone or tablet. It aims to see if home monitoring is as effective as in-person visits for keeping your lungs healthy.
OsloAges 18 years+ - NCT07516769RecruitingPhase 3
Nicorandil to reduce inflammation in active rheumatoid arthritis
This study tests whether nicorandil, a heart medication with anti-inflammatory properties, can help reduce joint inflammation and swelling in people with active rheumatoid arthritis who are already taking conventional disease-modifying drugs. The goal is to see if it provides additional relief from symptoms.
Tanta, Gharbia GovernorateAges 18–70 - NCT06758817Recruiting
Nutrition, gut health, and rheumatoid arthritis study
This trial tests if a specific diet can improve your rheumatoid arthritis symptoms by affecting your gut bacteria. You may be eligible if you have active RA and are willing to follow a special meal plan for several weeks.
Lisbon, PortugalAges 18 years+ - NCT07515638Recruiting
Immune System Study for Autoimmune Diseases
This research study collects samples and information from people with rheumatoid arthritis, lupus, or scleroderma, plus healthy volunteers, to better understand how the immune system works in these conditions. By comparing these groups, researchers hope to find new ways to treat and manage autoimmune diseases.
MontpellierAges 18 years+ - NCT06189495RecruitingPhase 2
Study of Genakumab for lung scarring from connective tissue disease
This study tests a new injected medication (Genakumab) for people with connective tissue disease-related lung scarring. It aims to see if it helps stabilize or improve lung function safely.
Beijing, Beijing MunicipalityAges 18–75 - NCT07473154RecruitingPhase 1/Phase 2
Calming an overactive immune system with special cells
This trial tests a new type of cell therapy made from a patient's own white blood cells (called lymphocytes) that are designed to help control the immune system. The goal is to reduce inflammation and symptoms in people with hard-to-treat rheumatoid arthritis or a severe form of scleroderma (dcSSc).
DüsseldorfAges 18 years+ - NCT07463937Recruiting
Study of Methotrexate Injections in Rheumatoid Arthritis
This study looks at how well methotrexate injections work in people with rheumatoid arthritis. It is designed for patients who are starting or changing to this type of methotrexate treatment.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07469540Recruiting
Exercise to lower heart risk in kidney disease or arthritis
This study tests whether a supervised aerobic exercise program can lower heart and blood vessel risk in people with kidney disease or rheumatoid arthritis. If you have one of these conditions and are not on dialysis, you may be able to join.
BesançonAges 50 years+ - NCT07438652Recruiting
Mediterranean vs paleo diet for rheumatoid arthritis
This 12-week study compares two diets (Mediterranean and paleo) to see which one better helps rheumatoid arthritis symptoms, muscle health, and quality of life. It is for adults aged 40 to 60 who have been diagnosed with rheumatoid arthritis.
Cairo, Al-ManialAges 40–60 - NCT07423533RecruitingPhase 2
GenSci120 injection for moderate to severe rheumatoid arthritis
This trial tests a new injection called GenSci120 for people with moderate to severe rheumatoid arthritis who haven't improved enough after trying at least one standard arthritis medication. The goal is to see if this treatment can help reduce joint pain and swelling.
Beijing, Beijing MunicipalityAges 18–70 - NCT07403188Recruiting
Long-Term Follow-Up Study for KYV-101 Participants
This long-term follow-up study checks on the health and safety of people who have already received the experimental cell therapy KYV-101 in a previous clinical trial. It is a way for them to be monitored over time without any additional treatments.
Denver, ColoradoAges 18 years+ - NCT06129214Recruiting
Partial tendon cleaning to reduce knee clicking after replacement
This trial studies a partial cleaning procedure on the quadriceps tendon during knee replacement to reduce clicking or rubbing sensation (crepitus). It is only for people getting a specific type of knee implant (posterior-stabilized) and whose kneecap is not replaced.
Seoul, GangnamGuAges 19 years+ - NCT03987633Recruiting
Study links health records and samples to understand health gaps
This study asks people affected by a specific illness (or their family member) to share saliva (and sometimes blood) and answer health and quality-of-life questions. The goal is to better understand and reduce health inequality by matching new information with medical records.
Wolverhampton, West MidlandsAges 6 years+ - NCT07321340Recruiting
Optimizing insoles for rheumatoid arthritis patients
This trial tests whether custom-fit insoles can improve foot pain and walking for people with rheumatoid arthritis. It aims to find the best insole design for each patient.
Saint-EtienneAges 18 years+ - NCT07295847RecruitingPhase 1
Study of AZD0120 for autoimmune diseases
This trial tests if a new medication, AZD0120, is safe for people with autoimmune diseases. It aims to help patients by targeting the immune system.
Tucson, ArizonaAges 18–75 - NCT07246096RecruitingEarly Phase 1
CAR-T cell therapy for autoimmune diseases
This trial tests a new CAR-T cell treatment for people with certain autoimmune diseases that have not responded to standard therapies. The treatment uses your own immune cells modified to target and attack disease-causing cells.
ShanghaiAges 18–70 - NCT07237659RecruitingPhase 1
Testing safety of NTR-1011 in lupus and rheumatoid arthritis
This trial is testing a new medicine called NTR-1011 to see if it is safe and tolerable for people with lupus or rheumatoid arthritis. If you have active lupus or RA and are on a stable treatment plan, you may be able to join.
Apple Valley, CaliforniaAges 18–75 - NCT07221565Enrolling by invitationPhase 1/Phase 2
Immune mapping trial for autoimmune conditions
This trial is testing a new way to map the immune system using electromagnetic signals and forecast how your body's immune system will respond. It may help people with autoimmune conditions like lupus or rheumatoid arthritis find new treatment options.
New York, New YorkAges Any age - NCT05003934RecruitingPhase 1
IV stem cell treatment safety study for rheumatoid arthritis
This Phase 1 trial tests how safe an intravenous (through a vein) stem cell product is for people with rheumatoid arthritis. It is mainly looking for side effects and safety rather than proving it works yet.
St John'sAges Any age - NCT05904301Recruiting
Registry for autoimmune and autoinflammatory disease patients
This study builds a nationwide list (registry) of people with certain autoimmune or inflammation-related illnesses. It helps researchers understand these diseases better over time, which can guide future care.
YerevanAges Any age - NCT06776965Recruiting
Ultra-processed foods and rheumatic disease study
This study explores how eating ultra-processed foods affects people with chronic rheumatic diseases like rheumatoid arthritis, spondyloarthritis, or osteoarthritis. It aims to understand if diet plays a role in symptom management.
LyonAges 18 years+
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Common questions
- Are there clinical trials for rheumatoid arthritis?
- Yes. Clin2 currently lists 263 recruiting rheumatoid arthritis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a rheumatoid arthritis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a rheumatoid arthritis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.