Clinical trials
SCD clinical trials
Below are recruiting scd clinical trials, each written for real people, not researchers. We’re tracking 62 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07395609Recruiting
Brain stimulation to boost memory, movement, and mood in older adults
This study tests whether high-frequency electrical stimulation of the brain can help improve thinking, movement, and mood in older adults who may or may not have early signs of memory decline. Participants will get sessions of stimulation and complete thinking and walking tasks.
Gainesville, FloridaAges 65–89 - NCT07383311Recruiting
Natural supplements for memory and sleep
This study tests whether certain natural compounds (autophagy enhancers) can improve sleep in people with age-related memory concerns, including those with mild cognitive impairment and those with only subjective declines.
Greifswald, Mecklenburg-VorpommernAges 55–75 - NCT07289061Recruiting
Positive psychology for early memory changes
This trial tests whether positive psychology exercises can help improve memory and brain function in people with very early memory changes. It may be a good fit if you have noticed new memory concerns or a mild cognitive impairment.
ThessalonikiAges Any age - NCT07286448Recruiting
Digital Brain Training for Mild Memory Problems
This trial tests a personalized digital brain training program for people with mild memory or thinking problems. It aims to see if the training can boost cognitive fitness and help maintain your thinking skills.
Modena, Reggio Nell'Emilia (RE)Ages 50 years+ - NCT06887907Recruiting
Studying megakaryocytes in sickle cell disease
This trial looks at the cells that help make platelets (megakaryocytes) in people with sickle cell disease. By comparing these cells when you are feeling well and during a pain crisis or chest syndrome, researchers hope to learn more about the condition and find better treatments.
Toulouse, FranceAges 18 years+ - NCT06889818Recruiting
Alzheimer's treatment and diagnostics registry study
This study creates a registry for people who are using newly approved Alzheimer's medications. It tracks how these treatments work over time and may help researchers learn more about diagnosing and treating Alzheimer's.
IncheonAges 19 years+ - NCT07236190RecruitingPhase 2
Testing NPC-1 for people with Alzheimer's signs
This study tests whether a medicine called NPC-1 can help people with mild memory or thinking problems or early-stage Alzheimer's. It looks at a blood marker to see if the treatment may slow down the disease.
Boston, MassachusettsAges 55 years+ - NCT07224360RecruitingPhase 2
Safety of a new drug for sickle cell pain
This study tests a new medicine called anumigilimab to see if it is safe for people with sickle cell disease. The study focuses on those who have had pain crises recently, to help manage and prevent them.
Little Rock, ArkansasAges 18 years+ - NCT07212504Recruiting
Brain stimulation to improve memory in older adults with mild memory problems
This study tests a new type of brain stimulation called accelerated neuromodulation, aimed at improving memory and thinking in older adults with mild memory issues. It uses magnetic pulses to gently stimulate a part of the brain linked to memory.
Toronto, OntarioAges 55–85 - NCT07213700Recruiting
Alzheimer's disease long-term study
This study follows people with Alzheimer's disease over time to learn more about the condition and improve future care. It is an observational study, meaning participants receive their usual care while researchers collect information.
MelbourneAges 18 years+ - NCT07206095Recruiting
Better diagnosis for inherited red blood cell diseases
This trial aims to improve how doctors diagnose rare inherited anemias, including sickle cell disease and other conditions that destroy red blood cells. It may help if you have a confirmed or suspected diagnosis but need more clarity through advanced testing.
Barcelona, BarcelonaAges Any age - NCT07187973RecruitingPhase 1
Study of DISC-3405 for people with sickle cell disease
This trial tests an investigational drug called DISC-3405 in people with sickle cell disease (SCD) to see if it is safe and how it affects your body. It may be an option if you have certain SCD complications or lab results.
Birmingham, AlabamaAges 18 years+ - NCT07188766Recruiting
Different IV fluid amounts for sickle cell pain crisis
This study compares two ways of giving IV fluids (lighter vs. more fluids) to adults with sickle cell disease who are in the hospital for a painful crisis. The goal is to see which approach helps you feel better sooner.
Dammam, Eastern ProvinceAges 18–60 - NCT07130669RecruitingPhase 1/Phase 2
Memory and thinking study for older adults
This trial tests a program to help maintain or improve memory and thinking skills in older adults. You may join if you are 60-89, speak English, and live at home or in an assisted-living facility.
Palo Alto, CaliforniaAges 60–89 - NCT05014893Recruiting
Brain testing and rehab study for thinking changes
This study looks at how brain activity relates to thinking problems and whether a cognitive (thinking) assessment and rehab approach can help adults with memory or thinking changes. You may be asked to take thinking tests and complete study activities during rehab.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07064174Recruiting
Sickle cell kidney research study
This study collects kidney tissue samples from people with sickle cell disease and healthy volunteers to better understand how sickle cell affects the kidneys. If you have sickle cell disease or a related blood disorder, you may help researchers find new ways to protect kidney function.
Dallas, TexasAges 18–65 - NCT07015684RecruitingPhase 1
Radioactive antibody and transplant for advanced sickle cell disease
This trial tests a radioactive antibody (131I-apamistamab) as part of conditioning before a stem cell transplant from a matched sibling donor. It aims to make the transplant safer and more effective for people with severe sickle cell disease.
New York, New YorkAges 12–50 - NCT06941389Recruiting
Comparing stem cell transplant vs standard therapy for sickle cell disease
This study compares two treatment approaches for children with sickle cell anemia: a stem cell transplant from a matched family donor versus continuing regular disease-modifying medicines. It aims to see which treatment works better over time.
Birmingham, AlabamaAges 3–20 - NCT06896825Recruiting
Staying active with social support and stress relief
This study tests whether a program that combines social support and stress management can help older adults who live alone become more physically active. You'll use a smartphone to track your activity and get support from others.
Phoenix, ArizonaAges 60 years+ - NCT06619197Recruiting
Reflexology in Sickle Cell Disease Study
This study tests if foot reflexology, a gentle pressure technique on your feet, can help relieve pain from a sickle cell crisis while in the hospital. It is only for children and teens under 18.
BronAges Up to 18 years - NCT06761560RecruitingPhase 2/Phase 3
Hydroxyurea dosing for children with sickle cell anemia
This study looks at whether adjusting the dose of hydroxyurea based on drug levels in the blood works better than the standard approach for treating sickle cell disease in children. It aims to reduce side effects and improve treatment outcomes.
Montreal, QuebecAges 6 months–18 years - NCT06758154Recruiting
Electro-acupuncture for subjective cognitive decline
This study tests whether electro-acupuncture can improve thinking and memory in people with subjective cognitive decline (when you notice memory issues but standard tests are still normal). It involves receiving acupuncture and brain scans over a period of time.
Nanjing, JiangsuAges 55–79 - NCT06669546Recruiting
Quiet sounds during deep sleep for memory in older adults
This study tests whether playing a soft, silent sound (or no sound) during deep sleep can improve memory, brain activity, and blood markers. It is for older adults (60-85) who have mild memory issues but are otherwise healthy.
BernAges 60–85 - NCT06665997RecruitingPhase 4
Depot shot for pain in women with sickle cell disease
This study tests if a hormone shot (depot medroxyprogesterone acetate) can help reduce pain episodes in women with sickle cell disease. It aims to see if the shot improves pain and markers of inflammation.
Atlanta, GeorgiaAges 18–50
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Common questions
- Are there clinical trials for scd?
- Yes. Clin2 currently lists 62 recruiting scd studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a scd trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a scd trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.